Biopiper TZ Injection 4.5 gm

Written By Divya L , PharmaD

Reviewed By Sunny S , MBBS

MRP ₹447

(Inclusive of all Taxes)

₹67.0 Cashback (15%)

Provide Delivery Location

Non returnable*

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COD available

Online payment accepted

Prescription drug

Whats That

About Biopiper TZ Injection

Biopiper TZ Injection belongs to the 'Antibiotics' class of drugs, primarily used to treat bacterial infections. It is used to treat various hospital-acquired and ventilator-associated pneumonia, urinary tract infections, intra-abdominal infections, skin and soft tissue infections (like diabetic foot infections) and uterine infections. Bacterial infection occurs when harmful bacteria grow in the body and causes illness. It can infect any part of the body and multiply very quickly.

Biopiper TZ Injection contains two medicines, namely: Piperacillin (Penicillin antibiotic) and Tazobactam (beta-lactamase inhibitor). Piperacillin belongs to the class of 'Penicillin antibiotics.' It has bactericidal (ability to kill bacteria) activity against gram-positive and gram-negative aerobic (requires oxygen to survive) and anaerobic (survives with little or no oxygen) bacteria. Piperacillin acts by binding to the penicillin-binding proteins (PBPs) inside the bacterial cell wall and inhibits its cell wall synthesis. Tazobactam is a beta-lactamase inhibitor. Beta-lactamases are the enzymes produced by bacteria to gain multi-resistance to β-lactam antibiotics, such as penicillins and cephalosporins. Tazobactam prevents the breakdown of other antibiotics by beta-lactamase enzyme-producing organisms. In Biopiper TZ Injection , Tazobactam works by preventing bacteria from destroying Piperacillin.

Biopiper TZ Injection will be administered by a healthcare professional. Like all medicines, Biopiper TZ Injection also causes side effects, although not everybody gets them. Common side effects of Biopiper TZ Injection include nausea, constipation, diarrhoea, headache, and trouble sleeping. If any of these effects persist or worsen, seek medical advice promptly.

Brief your medical history to the doctor if you have any allergic reactions to antibiotics. Please inform your doctor if you have any liver, kidney diseases, bleeding disorders, and fits before using Biopiper TZ Injection . Do not use Biopiper TZ Injection while having vaccinations with live bacterial vaccines (typhoid vaccine) since Biopiper TZ Injection may affect vaccines' activity. Biopiper TZ Injection should be used during pregnancy only if the doctor advises you. It is also excreted into breast milk in small amounts. Hence, it is recommended to consult your doctor if you are pregnant or breastfeeding before taking Biopiper TZ Injection .

Uses of Biopiper TZ Injection

Bacterial infections, hospital-acquired and ventilator-associated pneumonia, urinary tract infections, intra-abdominal infections, skin and soft tissue infections, and uterine infections.

Directions for Use

Biopiper TZ Injection will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Biopiper TZ Injection contains two medicines, namely: Piperacillin and Tazobactam. Piperacillin is a Penicillin antibiotic. It acts by binding to the penicillin-binding proteins (PBPs) inside the bacterial cell wall and inhibits its cell wall synthesis. Tazobactam is a beta-lactamase inhibitor that prevents the breakdown of other antibiotics by beta-lactamase enzyme-producing organisms. In Biopiper TZ Injection , Tazobactam works by preventing bacteria from destroying Piperacillin. Thus, Biopiper TZ Injection helps treat various bacterial infections of the stomach, lungs, skin and uterus.

Storage

Keep out of sight and reach of children.

Side effects of Biopiper TZ Injection 4.5 gm

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Constipation

Here are the steps to cope with constipation as a side effect of medication:

Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Vomiting

To prevent, manage, and treat Constipation caused by medication usage, follow these steps:

Preventing Vomiting (Before it Happens)
Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
Having a small meal before taking your medication can help reduce nausea and vomiting.
Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
Managing Vomiting (If it Happens)
Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
What to Do if Vomiting Persists
Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Indigestion

Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:

Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

Stomach Pain

Drink water or other clear fluids.
To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
Include bland foods like rice, toast, crackers, and rice in your diet.
Avoid lying down immediately after eating as it may cause indigestion or heartburn.
Avoid acidic and spicy food as it may cause indigestion.

Loose Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Drug Warnings

If you have a history of any cystic fibrosis (damaged lungs and digestive system), kidney disease, fits, colitis (inflammation of the colon), bleeding disorders, or heart or liver diseases, please inform your doctor before starting Biopiper TZ Injection . Please seek medical advice if you are pregnant or breastfeeding before taking Biopiper TZ Injection . Patients aged above 65 years are not at an increased risk of having side effects. However, the dosage should be adjusted if the patient has a history of renal impairment. Safety and efficacy of Biopiper TZ Injection in children less than two months of age have not been established.

Drug-Drug Interactions

PiperacillinVancomycin

Severe

PiperacillinHeparin

Severe

Drug-Drug Interactions

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PiperacillinVancomycin

Severe

How does the drug interact with Biopiper TZ Injection 4.5 gm:
Coadministration of Vancomycin with Biopiper TZ Injection 4.5 gm can increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Vancomycin with Biopiper TZ Injection 4.5 gm may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medication without consulting a doctor.

PiperacillinHeparin

Severe

How does the drug interact with Biopiper TZ Injection 4.5 gm:
When used together Biopiper TZ Injection 4.5 gm will raise the amount of anticoagulant(blood thinners, are chemical substances that prevent or reduce clotting of blood) effect of heparin.

How to manage the interaction:
Although there is a possible interaction between Biopiper TZ Injection 4.5 gm and Heparin, you can take these medicines together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Include more fibre-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread, and brown rice should be included in your diet.
Eating grapefruit during antibiotics treatment can prevent the body from utilizing Biopiper TZ Injection properly. So, avoid intake of grapefruit or grapefruit juice with the antibiotic.
Avoid intake of alcoholic beverages with Biopiper TZ Injection as it can make you dehydrated and affect your sleep. This can make it more challenging for your body to aid the Biopiper TZ Injection in fighting off infections.
Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
Do not walk barefoot at places like gym showers to prevent bacterial infections.

Side Effects of Biopiper TZ Injection

Nausea
Constipation
Diarrhoea
Headache
Trouble sleeping

Habit Forming

No

Therapeutic Class

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Author Details

Written By

Divya L

PharmaD

Reviewed By

Sunny S

MBBS

Last Updated

Jul 8, 2025 | 9:33 AM IST

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Biopiper TZ Injection work?

Biopiper TZ Injection contains Piperacillin and Tazobactam. Piperacillin inhibits bacterial cell wall synthesis, and Tazobactam prevents the bacteria from gaining resistance against Piperacillin. Thus Biopiper TZ Injection helps in treating various bacterial infections.

In which conditions should I stay cautious while using Biopiper TZ Injection ?

Biopiper TZ Injection should be used with proper caution and doctor consultation if you have any cystic fibrosis (damaged lungs and digestive system), kidney disease, fits, colitis (inflammation of the colon), bleeding disorders, heart or liver diseases and undergoing dialysis.

I am undergoing vaccination for typhoid this week, can I use Biopiper TZ Injection ?

Biopiper TZ Injection can affect live vaccines like typhoid vaccine and decrease their effectiveness. Please consult a doctor before you start Biopiper TZ Injection if you are undergoing any vaccinations.

Can I stop taking Biopiper TZ Injection on my own?

It is recommended to complete the course of Biopiper TZ Injection even if you feel better as it is an antibiotic, and stopping it midway may lead to recurring infections. Continue taking Biopiper TZ Injection for as long as your doctor has prescribed to treat your condition effectually.

Drug-Drug Interactions Checker List

HEPARIN
METHOTREXATE
TOBRAMYCIN
VANCOMYCIN
PROBENECID
VECURONIUM

Special Advise

Renal, hepatic, and blood function tests are advised during prolonged therapy to rule out any toxicity caused due to overdose of Biopiper TZ Injection .
Clostridium difficile-associated diarrhoea (CDAD) is reported during the usage of antibiotics like Biopiper TZ Injection . Please see your doctor if you experience prolonged diarrhoea.
Penicillin antibiotics are easily removed during dialysis; hence let your doctor know if you are undergoing dialysis treatment so that the dose can be scheduled after the dialysis.
Biopiper TZ Injection may also affect urine glucose tests; hence inform your doctor beforehand if you are using Biopiper TZ Injection .

Disease/Condition Glossary

Bacterial infection occurs when harmful bacteria grow in the body and causes illness. It can infect any part of the body and multiply very quickly. Bacteria occur in three basic shapes: spherical, rod and spiral-shaped. Bacteria may be gram-positive (have thick cell wall) or gram-negative (do not have a cell wall). Some common symptoms of a bacterial infection include cough, fever and tiredness.

Hospital-acquired pneumonia/ nosocomial pneumonia: It is a lower respiratory infection of the lungs that occurs during a hospital stay.

Ventilator-associated pneumonia: A lung infection occurs in people who are on mechanical ventilation breathing machines in hospitals.