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  3. Biotil 500 Tablet 10's

Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Non returnable*
COD available

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Composition :

CEFUROXIME-500MG

Manufacturer/Marketer :

Shef Biotech Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Biotil 500 Tablet

Biotil 500 Tablet belongs to the class of antibiotics known as cephalosporin, indicated for treating a wide range of bacterial infections. It helps in the treatment of urinary tract infections (UTI), Mild to moderate lower respiratory tract infections (bronchitis), severe lower respiratory tract infections (pneumonia), pyelonephritis (kidney inflammation due to the bacterial infection), uncomplicated gonorrhoea (sexually transmitted infection), Lyme disease (caused due to biting of infected black-legged tick insect) in adults and children above 12 years of age.

Biotil 500 Tablet is a broad-spectrum antibiotic that kills a wide range of bacteria (bactericidal). It kills the bacterial cell by binding to the outer layer of the bacteria and blocking the activity of the enzyme that makes peptidoglycan (a vital component of the bacterial cell wall). As a result, the bacterial cell cannot grow and multiply and finally gets killed.

You should take Biotil 500 Tablet only if your doctor has prescribed you. Biotil 500 Tablet is available in various forms, such as oral tablets, dispersible tablets, and oral suspension. Most bacterial infections get treated within one week, while some conditions might take longer. So, it would be best if you tried to complete the dose your doctor prescribed for the specific bacterial infection. During the treatment with Biotil 500 Tablet , you may observe some mild and transient nature of common side effects like headache, dizziness,  stomach upset, overgrowth of candida (fungal skin infection), unpleasant taste in the mouth, diaper rashes, and eosinophilia (increased disease-fighting cells WBCs). These side effects are usually in the initial phase and then resolved after some time. However, if these side effects persist, let your doctor know about them.

Overdosage of Biotil 500 Tablet can cause brain problems (cerebral irritation with fits or convulsions attack). There is no clinical evidence of a Biotil 500 Tablet effect on the mother or baby during pregnancy. However, one should take the Biotil 500 Tablet with caution. Biotil 500 Tablet is excreted in the breastmilk, so the nursing mother should cautiously take Biotil 500 Tablet . This antibiotic may cause dizziness, so patients should be cautious while driving a motor vehicle or operating machinery. Biotil 500 Tablet is not recommended for people allergic or hypersensitive to Biotil 500 Tablet , penicillin, or other beta-lactam antibiotics. In the initial stage of the treatment, you might have diarrhoea and abdominal cramps due to loss of gut flora (good intestinal/gut bacteria that aids digestion). So, the doctor may prescribe you prebiotics or probiotics to increase the number of gut flora. You can drink alcoholic beverages while taking amoxicillin, as it does not interact with Biotil 500 Tablet . Liver and kidney-affected people should take this medication with caution.

Uses of Biotil 500 Tablet

Bacterial infections

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it.Suspension/Syrup: Shake the bottle well before use. Check the label for directions and take Biotil 500 Tablet in doses as prescribed by your doctor with the help of a measuring cup.Dispersible Tablet: Check the label for directions before use. Disperse the tablet in the prescribed amount of water and swallow the whole contents.

Medicinal Benefits

Biotil 500 Tablet treats a wide range of bacterial infections caused due to gram-positive and gram-negative bacteria. It helps treat respiratory tract infections, ear infections, skin infections, genitourinary infections, and bone infections. Besides this, Biotil 500 Tablet also prevents in spreading of the infection after surgery and in the early treatment of Lyme disease caused by bacteria (Borrelia burgdorferi) in adults and children over the age of 12 years. The usual course of Biotil 500 Tablet is seven days (5-10 days). But, your doctor might prescribe you Biotil 500 Tablet for a longer duration depending on the condition of infection. Biotil 500 Tablet has excellent antibacterial activity against gram-positive and gram-negative bacteria, including Staphylococcus aureus, Haemophilus para influenza, Streptococcus pneumonia, S. pyrogens, Haemophilus influenzae, Klebsiella pneumoniae, Moraxella catarrhalis, and Neisseria gonorrhoeae.

Storage

Store in a cool and dry place away from sunlight
Side effects of Biotil 500 Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Stay hydrated by taking water, juices and soups etc.
  • Eat fruits and vegetables which contain vitamins.
  • Take iron rich food like dry fruits, green leafy vegetables and sea food etc.
  • Reduce intake of milk, cheese, yogurt, soy, chocolate, ice cream, grapes, popcorn, canned salmon, pomegranate.
  • Regular exercise like walking, jogging is helpful.
  • Eosinophil levels can be lowered by eating fruits and vegetables, avoiding smoking, and consuming alcohol in moderation.
  • Several foods, such as ginger, garlic, pepper, turmeric, and honey, might boost immunity.
  • Avoid dairy products, including cheese, yoghurt, and milk.
  • Drink water and keep yourself hydrated.
  • Inflammation of Vagina needs immediate attention and cannot be ignored.
  • Get a physical examination and prevent wearing clothes that can hold heat and moisture.
  • Avoid using vaginal sprays or perfumed soaps that increase itching and irritation.
  • Follow your doctor's instructions, and rest well with proper medication.
  • Take a balanced diet and get regular screenings to reduce inflammation.
  • High levels of liver enzymes need immediate medical attention.
  • Watch your diet and consume low-fat foods, like green leafy vegetables, fish, whole grains, nuts, etc.
  • Regularly do strengthening exercises to control your cholesterol levels.
  • Avoid drinking alcohol as it can affect your liver.
  • Focus on losing weight as it can help control cholesterol and maintain liver enzymes.
  • Practice yoga and meditation to improve liver functioning and overall health.
Managing Medication-Triggered Thrombophlebitis (Inflammation of a vein): A Step-by-Step Guide:
  • If you have symptoms such as pain, swelling, redness, or warmth in your veins after taking medication, contact your doctor right once. Share information about your symptoms, medication regimen, and medical history.
  • Your doctor will then assess your medication regimen to determine if it's contributing to the thrombophlebitis. This assessment will help identify the best course of action to manage your condition and prevent further complications.
  • Your doctor may suggest certain diet and lifestyle changes to help manage your condition. This may include increasing your intake of foods rich in omega-3 fatty acids, staying hydrated, exercising regularly, and maintaining a healthy weight. Your doctor may also advise medications to reduce inflammation, prevent blood clots, or manage pain if necessary.
  • If your condition does not improve or persists, consult your doctor and report your condition. Your doctor will assess your progress, adjust your treatment plan if necessary, and provide appropriate advice to ensure the best possible outcome.

Drug Warnings

Special care should be taken by the people taking Biotil 500 Tablet who have allergic reactions to penicillin or other beta-lactam antibiotics. Use with other antibiotics may lead to a fungal skin infection known as Candida. Prolonged use of Biotil 500 Tablet may also cause an overgrowth of other pathogens (like enterococci and Clostridium difficile), which can be prevented by stopping Biotil 500 Tablet . The case of colitis (inflammatory bowel disease) has been reported using Biotil 500 Tablet . Hence, it is important to consider the proper diagnosis of the patients who developed diarrhoea after taking Biotil 500 Tablet . If the symptom of diarrhoea persists for a longer duration, the patient may experience abdominal cramps. In this situation, you should discontinue the intake of Biotil 500 Tablet immediately. The Jarisch-Herxheimer reaction (caused due to toxins released by the death of bacteria within the body during antibiotic treatment) has been seen in the patients taking Biotil 500 Tablet for the treatment of Lyme disease. Your ability to perform tasks that require judgment, cognitive, or body movement may be affected, and you may have dizziness. So patients taking Biotil 500 Tablet should be warned to be cautious when driving or operating machinery.

Drug-Drug Interactions

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CefuroximeBCG vaccine
Severe
CefuroximeLepirudin
Severe

Drug-Drug Interactions

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CefuroximeBCG vaccine
Severe
How does the drug interact with Biotil 500 Tablet:
Co-administration of Biotil 500 Tablet may reduce the anti-tumor activity of BCG in the bladder.

How to manage the interaction:
Talk to your doctor before receiving BCG if you are currently being treated with Biotil 500 Tablet. To ensure adequate response to your treatment, you should not receive BCG until after you complete your antibiotic therapy. Do not discontinue the medication without consulting a doctor.
CefuroximeLepirudin
Severe
How does the drug interact with Biotil 500 Tablet:
The therapeutic efficacy of Lepirudin can be decreased when used in combination with Biotil 500 Tablet.

How to manage the interaction:
Although taking Biotil 500 Tablet and Lepirudin together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without a doctor's advice.
How does the drug interact with Biotil 500 Tablet:
Co-administration of Dalteparin and Biotil 500 Tablet can increase the blood levels and effects of Dlateparin.

How to manage the interaction:
Taking Biotil 500 Tablet with Dalteparin together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Biotil 500 Tablet:
Taking these medications together might make it harder for your body to absorb atazanavir, which could make it less effective.

How to manage the interaction:
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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • It would be best to take probiotics after taking the full course of Biotil 500 Tablet to restore some of the healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Thus fibre foods may help restore healthy gut bacteria after taking a course of antibiotics. Whole grains like whole-grain bread, and brown rice, should be included in your diet.
  • Avoid taking too much calcium enriched foods and drinks as it might affect the working of Biotil 500 Tablet .
  • Avoid intake of alcoholic beverages with Biotil 500 Tablet as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Biotil 500 Tablet in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTI- BACTERIALS

Author Details

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Drug-Diseases Interactions

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CEFUROXIME-500MGOther gastroenteritis and colitis of infectious and unspecified origin
Severe
CEFUROXIME-500MGChronic kidney disease
Moderate

Drug-Diseases Interactions

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CEFUROXIME-500MGOther gastroenteritis and colitis of infectious and unspecified origin
Severe
How does the disease interact with Biotil 500 Tablet:
Colitis: In some cases the use of Biotil 500 Tablet may cause ranging from mild diarrhea to fatal colitis. Colitis is commonly Clostridioides difficile-associated diarrhea (CDAD). Discontinue therapy if signs of CDAD are confirmed.

How to manage the interaction:
Antibiotics may cause Clostridioides difficile-associated diarrhoea (CDAD), which may range from mild diarrhoea to fatal colitis. Biotil 500 Tablet should be used with caution in patients with a history of gastrointestinal disease, particularly colitis (inflammation of the colon) or pseudomembranous colitis (a severe inflammation of the inner lining of the large intestine). Appropriate fluid and electrolyte management, protein supplementation, antibacterial treatment of C difficile, and surgical evaluation is advised.
CEFUROXIME-500MGChronic kidney disease
Moderate
How does the disease interact with Biotil 500 Tablet:
Renal dysfunction: Biotil 500 Tablet is eliminated by the kidney in an unchanged form. Thus the plasma levels of the drug increase and prolongs the half-life. Adjust the doses of Biotil 500 Tablet as necessary.

How to manage the interaction:
The serum concentration may be increased in patients with impaired kidney function as most beta-lactam antibiotics are eliminated by the kidney. Dose adjustment may be necessary for patients with kidney dysfunction. Regular renal function tests are advised during prolonged or high-dose therapy.
CEFUROXIME-500MGDependence on enabling machines and devices, not elsewhere classified
Moderate
How does the disease interact with Biotil 500 Tablet:
Dialysis : Most of the antibiotics are eliminated by hemodialysis. Therefore, administer Biotil 500 Tablet after dialysis or an additional dosage to be administered.

How to manage the interaction:
Biotil 500 Tablet serum levels may be decreased by hemodialysis and peritoneal dialysis. Supplemental doses should be given at the end of each hemodialysis session.
CEFUROXIME-500MGConvulsions, not elsewhere classified
Moderate
How does the disease interact with Biotil 500 Tablet:
seizure disorders: In some patients, seizures were reported with whom renal dysfunction which incase of dosage adjustment was not done. Discontinue Biotil 500 Tablet if seizures are reported.

How to manage the interaction:
Cephalosporin antibiotics may trigger seizures. Biotil 500 Tablet should be discontinued if seizures associated with drug therapy occur.
CEFUROXIME-500MGOther diseases of liver
Moderate
How does the disease interact with Biotil 500 Tablet:
liver disease: With Biotil 500 Tablet, a transient increase in the AST, ALT, and alkaline phosphatase levels was observed. Use with caution and closely monitor for hepatic function is recommended.

How to manage the interaction:
Caution and monitoring is recommended in patients with liver disease as cases of hepatitis have been reported with the use of certain cephalosporins.
CEFUROXIME-500MGOther diseases of liver
Moderate
How does the disease interact with Biotil 500 Tablet:
Rarely, cephalosporins use may cause hypoprothrombinemia, with or without bleeding. Monitor for Prothrombin time.

How to manage the interaction:
Cephalosporins may be associated with reduced prothrombin activity/prolonged prothrombin time (blood takes too long to form a clot). Prothrombin time should be monitored in at-risk patients and managed as needed.

FAQs

Drug-Drug Interactions Checker List

  • OMEPRAZOLE
  • PROBENECID
  • MYCOPHENOLIC ACID

Disease/Condition Glossary

A bacterial infection is a condition in which harmful bacteria enter, multiply and infect our body. It can target any body part and multiple very quickly. When you get infected with bacteria, you can experience generalized symptoms like fevers, chills, and fatigue. Bacteria are of various forms comprising commonly spherical, rod, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. Few harmful bacteria that cause infections include Streptococcus, Staphylococcus, and E. coli. Anyone can become infected with a bacterial infection. But, people with weak immune systems or taking immunosuppressive medicine can make you more prone to bacterial infection.

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