Bonestat Capsule 15's

Bonestat Capsule 15's belongs to the class of ‘Multi-minerals’ primarily used to treat low blood calcium levels. Bonestat Capsule 15's effectively treats various conditions caused by low calcium levels in the body, such as osteoporosis (weak and brittle bones), osteomalacia/rickets (weak bones), hypoparathyroidism (low levels of parathyroid hormone), and latent tetany (a muscle disease with low blood calcium levels). Bonestat Capsule 15's can also be given to pregnant, nursing, and postmenopausal women to ensure that they are getting enough calcium. Additionally, Bonestat Capsule 15's is used to treat hyperparathyroidism (overactive parathyroid glands) and metabolic bone disease in people with chronic kidney disease, surgery, or other conditions.

Bonestat Capsule 15's consists of three medicines, namely: Calcium carbonate (mineral), Calcitriol (Vitamin D3), and  Zinc (mineral). Calcium is a mineral that is used to prevent or treat a calcium deficiency. It provides essential nutrients to maintain bone formation and maintenance. Calcitriol is a synthetic version of Vitamin D3 and treats calcium deficiency with hypoparathyroidism (the parathyroid glands' decreased activity) and metabolic bone diseases in people with chronic kidney failure. It raises Vitamin D levels and thereby increases calcium levels in the blood. This helps in improving the absorption rate of calcium from the intestine. Zinc is a mineral that has an essential role in bone health. Zinc helps to stimulate osteoblastic bone formation and mineralization.

Take Bonestat Capsule 15's as instructed by your doctor. In some cases, Bonestat Capsule 15's can cause side effects like constipation or stomach upset, nausea, vomiting, loss of appetite, mood changes, weakness, tiredness, fast or pounding heartbeat, bone/muscle pain, and headache. Most of these side effects of Bonestat Capsule 15's do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

If you are known to be allergic to Bonestat Capsule 15's or its inactive components, please inform your doctor. Pregnant or breastfeeding women should consult their doctor before taking Bonestat Capsule 15's. Higher doses of Vitamin D than the recommended daily dose should be used in pregnant women only when advised by the doctor. Bonestat Capsule 15's may pass into the breast milk. Hence breastfeeding mothers need to seek medical advice before starting Bonestat Capsule 15's. Bonestat Capsule 15's may contain sugar or sorbitol; hence caution should be taken to have sugar intolerance, diabetes, and phenylketonuria (increased levels of an amino acid called phenylalanine).

Bonestat Capsule 15's is a combination of three drugs, namely; Calcium carbonate (mineral), Calcitriol (Vitamin D3) and Zinc (mineral) used to treat low blood calcium levels and various associated conditions caused by low calcium levels in the body, such as osteoporosis (weak and brittle bones), osteomalacia/rickets (weak bones), hypoparathyroidism (low levels of parathyroid hormone), and tetany (a muscle disease with low blood calcium levels). Calcium carbonate is a mineral and prevents or treats calcium deficiency. It helps to maintain bone and teeth health. Calcitriol, a synthetic form of Vitamin D3, treats calcium deficiency with hypoparathyroidism (the parathyroid glands' decreased activity) and metabolic bone diseases in people with chronic kidney failure. Zinc is an important mineral in the normal growth and development of the skeletal system. It helps maintain bone density by increasing protein synthetase, which helps protect bone health.

• Nausea
• Vomiting
• Headache
• Stomach pain
• Constipation
• Mood changes
• Tiredness/ weakness
• Fast or pounding heartbeat

If you are known to be allergic to Bonestat Capsule 15's or any other medicines, please tell your doctor. If you are pregnant or planning to become pregnant, it is advised to inform your doctor before using Bonestat Capsule 15's. Higher doses of Vitamin D than the recommended daily dose should be used in pregnant women only when advised by the doctor. Calcitriol in higher doses may harm the fetus. Bonestat Capsule 15's may pass into the breast milk; hence consult your doctor before taking Bonestat Capsule 15's if you are a breastfeeding mother. Bonestat Capsule 15's should be used with caution in children and only if recommended by a doctor. Calcitriol in Bonestat Capsule 15's can affect growth in children. Inform your doctor if your child is not growing at a normal rate while using Bonestat Capsule 15's. Bonestat Capsule 15's is not recommended if you have hypercalcemia (high calcium levels), metastatic calcification (extra deposits of calcium in the body), hypervitaminosis D (high vitamin D levels), and malabsorption syndrome (difficulty absorbing nutrition from food). Inform your doctor before taking Bonestat Capsule 15's if you have any heart/kidney/liver/blood vessel diseases, kidney stones, sarcoidosis (growth of inflammatory cells in different parts of the body), Crohn's disease (inflammatory bowel disease), Whipple's disease (bacterial infection affecting joints and digestive system), achlorhydria (little or no stomach acid), low levels of bile, and phosphate imbalance. Bonestat Capsule 15's contains sugar or sorbitol; hence caution should be taken to have an intolerance to sugars, diabetes, and phenylketonuria (increased levels of an amino acid called phenylalanine).

Drug-Drug Interactions: Bonestat Capsule 15's may interact with anti-cancer medication (estramustine), Cholestyramine (cholesterol-lowering agent), Digitalis (used to treat heart problems), medicines to treat bacterial infections such as Ciprofloxacin, Levofloxacin, Gatifloxacin, Sparfloxacin, Ofloxacin; Ketoconazole (treat fungal infections).

Drug-Food Interactions: Avoid or reduce the intake of caffeine, soft drinks, and alcohol that inhibit calcium absorption.

Drug-Disease Interactions: Inform your doctor if you have myeloma, bone metastases, primary hyperparathyroidism, Nephrolithiasis/nephrocalcinosis., Renal failure, or Hypervitaminosis D.

• ESTRAMUSTINE
• CHOLESTYRAMINE
• DIGITALIS
• CIPROFLOXACIN
• LEVOFLOXACIN
• GATIFLOXACIN
• SPARFLOXACIN
• OFLOXACIN
• KETOCONAZOLE

• Include dairy products like milk, yogurt, cheese, or milk-based custard in your diet.
• Eat daily a serving of broccoli, cabbage, bok choy, spinach, and other green leafy vegetables.
• Snack on calcium-rich nuts like Brazil nuts or almonds.
• Sprinkle sesame seeds over your food, vegetables, and salads. Sesame seeds are high in calcium.
• Avoid or reduce the intake of caffeine, soft drinks, and alcohol that inhibit calcium absorption.
• Replace the meat with tofu or tempeh for extra calcium in your food.

• Clinical monitoring of serum electrolyte concentrations and cardiac function is recommended.
• A low phosphate diet is recommended to control serum phosphorus levels in patients undergoing dialysis.

Osteoporosis: It is a bone disease that weakens and brittle bones by decreasing bone density.  As bones become less dense, they weaken and are more likely to break. Breaking a bone is a serious complication of osteoporosis, especially with older patients. Women are much more likely to develop osteoporosis than are men. Signs and symptoms include back pain caused by a fractured or collapsed vertebra, loss of height over time, a stooped posture, a bone that breaks much more easily than expected.

Osteomalacia/Rickets: A bone disease caused by softening and weakening bones in children due to inadequate vitamin D. Adults can experience a similar condition known as osteomalacia. It causes bone pain, poor growth, and soft, weak bones that can lead to bone deformities.

Tetany: A disease condition due to low levels of calcium (hypocalcemia) in the body causes cramps and spasms in the hands, feet, and larynx (voice box).

Hypoparathyroidism: It is a disease characterized by low levels of parathyroid hormone. This can cause low calcium levels and trigger tetany.