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  1. Home
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  3. Brufungin 50 Injection

Brufungin 50 Injection, Pack of 1 Injection
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
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Composition :

CASPOFUNGIN-50MG

Manufacturer/Marketer :

Brawn Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Brufungin 50 Injection

Brufungin 50 Injection belongs to the class of medicines known as 'antifungals' used to treat various fungal infections. A fungal infection is caused when a fungus invades and affects any body part.

Brufungin 50 Injection contains Caspofungin, which inhibits the formation of a fungal cell wall component required for the fungus to continue living and growing. When fungal cells are exposed to Caspofungin, their cell walls become partial or faulty, making them fragile and unable to grow. As a result, fungal cells get killed, or their growth is minimized.

A qualified healthcare professional will administer Brufungin 50 Injection. In some cases, you may experience certain common side effects, such as injection site reactions, headaches, dizziness, nausea, vomiting, diarrhoea, stomach pain, tremors, sweating, high blood pressure, difficulty sleeping and swelling of the hands, ankles, or feet. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before taking Brufungin 50 Injection, inform your doctor about your medical condition, sensitivities, and medications. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not use any other medicines with Brufungin 50 Injection without a doctor's recommendation. Brufungin 50 Injection may cause dizziness; therefore, avoid driving vehicles or operating machinery until you return to normal. Avoid the consumption of alcohol while on Caspofungin therapy.

Uses of Brufungin 50 Injection

Fungal infections

Directions for Use

A qualified healthcare professional will administer Brufungin 50 Injection. Kindly do not self-administer.

Medicinal Benefits

Brufungin 50 Injection is an antifungal agent, a medicine used to treat several fungal infections. It can be used to treat fungal infections that other drugs have failed to treat. It is also used to treat serious fungal infections in persons who have a reduced immune system. Brufungin 50 Injection works by killing or preventing fungi or yeast by inhibiting an enzyme in fungi responsible for its membrane formation. As a result, fungal cells get killed, or their growth is minimized.

Storage

Store in a cool and dry place away from sunlight
Side effects of Brufungin 50 Injection
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Eat foods rich in vitamin C, beta-carotene, and antioxidants, such as citrus fruits, orange vegetables, and berries.
  • Include healthy fats like fatty fish, avocados, and nuts in your diet.
  • Drink plenty of water and limit sun exposure to maintain skin hydration and protect against damage.
  • Practice stress management and relaxation techniques like deep breathing exercises, progressive muscle relaxation, and meditation.
  • Limit or avoid processed foods, sugary drinks, and excessive alcohol to prevent premature aging.
  • Consult a dermatologist if you experience significant changes in skin colour.
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.

Drug Warnings

It is recommended not to use Brufungin 50 Injection if you are allergic to any component present, so inform your doctor about your sensitivities with medicines and foods. Also, let your doctor know about your medical condition and the medications you are currently using. Do not use any other drugs with Brufungin 50 Injection without a doctor’s recommendation. Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Drug-Drug Interactions

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CaspofunginPhenytoin
Severe
CaspofunginEfavirenz
Severe

Drug-Drug Interactions

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CaspofunginPhenytoin
Severe
How does the drug interact with Brufungin 50 Injection:
Coadministration of Phenytoin and Brufungin 50 Injection may decrease the blood levels of Brufungin 50 Injection, which may make Brufungin 50 Injection less effective.

How to manage the interaction:
Although taking Phenytoin and Brufungin 50 Injection together can result in an interaction, it can be taken if your doctor has prescribed it. If your infection gets worse or if your symptoms don't go away, it is advised to consult a doctor. Without consulting a doctor, never stop taking any drugs.
CaspofunginEfavirenz
Severe
How does the drug interact with Brufungin 50 Injection:
Taking Brufungin 50 Injection and Efavirenz together reduces the levels and effectiveness of Brufungin 50 Injection.

How to manage the interaction:
Although taking Brufungin 50 Injection and Efavirenz together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without a doctor's advice.
CaspofunginLeflunomide
Severe
How does the drug interact with Brufungin 50 Injection:
Leflunomide can cause liver problems, and combining it with other drugs, such as binimetinib, can raise the risk.

How to manage the interaction:
There may be a possibility of interaction between Leflunomide and Brufungin 50 Injection, but it can be taken if prescribed by a doctor. If you have any of these symptoms, contact your doctor right away. These symptoms include liver problems, fever, rash, itching, loss of appetite, dark urine, stomach pain, unusual bleeding or bruising, feeling tired, and yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.
CaspofunginRifampicin
Severe
How does the drug interact with Brufungin 50 Injection:
Taking Rifampicin in combination with Brufungin 50 Injection may make Brufungin 50 Injection less effective.

How to manage the interaction:
There may be a possibility of interaction between Brufungin 50 Injection and Rifampicin, but it can be taken if prescribed by a doctor. Contact your doctor if your symptoms do not improve. Do not stop using any medications without first talking to your doctor.
CaspofunginCarbamazepine
Severe
How does the drug interact with Brufungin 50 Injection:
Taking carbamazepine and Brufungin 50 Injection together may result in decreasing the effects of Brufungin 50 Injection.

How to manage the interaction:
Although taking carbamazepine and Brufungin 50 Injection together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
CaspofunginFosphenytoin
Severe
How does the drug interact with Brufungin 50 Injection:
Coadministration of Brufungin 50 Injection and Fosphenytoin can reduce the levels of Brufungin 50 Injection in the body. This can lead to low treatment outcomes.

How to manage the interaction:
Although there is a possible interaction between Brufungin 50 Injection and Fosphenytoin, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without first talking to your doctor.
CaspofunginDexamethasone
Severe
How does the drug interact with Brufungin 50 Injection:
Co-administration of Dexamethasone with Brufungin 50 Injection may cause Brufungin 50 Injection to be less effective.

How to manage the interaction:
Although there is a possible interaction between Brufungin 50 Injection and Dexamethasone, you can take these medicines together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
CaspofunginKetoconazole
Severe
How does the drug interact with Brufungin 50 Injection:
Coadministration of ketoconazole with Brufungin 50 Injection may raise the risk of liver damage.

How to manage the interaction:
Although taking Ketoconazole and Brufungin 50 Injection together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor. Do not discontinue any medication without consulting a doctor.
CaspofunginNevirapine
Severe
How does the drug interact with Brufungin 50 Injection:
Using nevirapine together with Brufungin 50 Injection may cause Brufungin 50 Injection to be less effective.

How to manage the interaction:
Although there is a possible interaction between Brufungin 50 Injection and Nevirapine, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • It is advisable to follow a candida diet during fungal infections. This diet excludes sugar, gluten, certain dairy products, and alcohol. Switch to low-sugar fruits, non-starchy vegetables and gluten-free foods. A very high sugar or high-carbohydrate diet may increase the count of Candida in some people.
  • Create a well-balanced and healthy diet that includes vegetables, fruits, whole grains, legumes, omega-3-rich foods, and lean protein sources.
  • Limit or avoid alcohol consumption.
  • Quitting smoking is the best strategy to lower the risk of any disease.
  • Avoid sharing towels, combs, bedsheets, shoes or socks with others.
  • Wash your bedsheets and towels regularly.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS

Brufungin 50 Injection Substitute

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:49 AM IST

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Drug-Drug Interactions Checker List

  • KETOCONAZOLE
  • CARBAMAZEPINE
  • PHENYTOIN
  • EFAVIRENZ
  • NELFINAVIR

Disease/Condition Glossary

Fungal infections: Fungal infection occurs when a fungus enters, infects and multiplies in the body. Fungi can live in water, soil, air and plants. Fungi affect any body part, including the mouth, throat, oesophagus, lungs, bladder, genital area and blood. Mild fungal skin infections are common and can cause rashes. Fungal infections affecting body organs like the lungs can cause flu or tuberculosis. Some fungal diseases like cryptococcal meningitis and blood infections can be fatal. A few common fungal infections are yeast infections that affect the genital area, oesophagus and urinary tract caused by Candida.

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