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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
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Manufacturer/Marketer :

Lupin Ltd

Consume Type :

INHALATION

Return Policy :

Not Returnable

Expires on or after :

About Budamate 400 Transhaler

Budamate 400 Transhaler belongs to the respiratory combination medication primarily used to treat asthma symptoms and chronic obstructive pulmonary diseases (COPD). Asthma is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty breathing. COPD is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes).

Budamate 400 Transhaler is a combination of two drugs: Budesonide (corticosteroid) and Formoterol (LABA - long-acting beta-agonists or bronchodilator). Budesonide belongs to the corticosteroids class that works by reducing the irritation and swelling by acting inside the nasal passage and airways lining cells and stops the release of certain chemicals responsible for causing inflammatory reactions and allergies. Thereby, it provides relief from sneezing, runny or blocked nose and sinus discomfort. On the other hand, Formoterol belongs to LABA - long-acting beta-agonists or bronchodilators that relaxes and widens respiratory airways muscles, making it easier for asthma and COPD patient to breathe. 

Use Budamate 400 Transhaler as prescribed. Your doctor will recommend how often you use Budamate 400 Transhaler based on your medical condition. Some people may experience fungal infection in the mouth, headache, sore throat, hoarse voice, upper respiratory tract infection, flu, cough, back pain, increased heart rate, and trembling. Most of these side effects of Budamate 400 Transhaler do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to lactose (a form of sugar) or have lactose intolerance, Budamate 400 Transhaler or any other ingredients, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Budamate 400 Transhaler. Budamate 400 Transhaler is not recommended for children below 6 years of age. If your breathing worsens or you often wake up at night with asthma, experience chest tightness in the morning or last longer than usual, please consult a doctor immediately. These might be signs indicating that your asthma is not controlled properly and requires an alternate or additional treatment. Regular monitoring of potassium levels is recommended while taking Budamate 400 Transhaler as it may cause low potassium levels in the blood. If you have high blood pressure, diabetes, hypokalaemia (low potassium levels in the blood), glaucoma, cataracts, osteoporosis (weak bones), fits, immune system problems, chickenpox, measles, thyroid, lung, heart, liver or adrenal gland problems, inform your doctor before taking Budamate 400 Transhaler. Prolonged use of LABA (long-acting beta-agonists) or vasodilators drugs may cause symptoms like chest pain (angina), increased blood pressure (hypertension), a fast and irregular heart rate (palpitation), headache, tremor, and nervousness.

Uses of Budamate 400 Transhaler

Asthma, Chronic obstructive pulmonary disease (COPD)

Directions for Use

Inhaler/Transhaler/Turbuhaler: Shake the inhaler/Transhaler/turbuhaler well and check the label for directions before using it. Hold the inhaler/Transhaler/turbuhaler with the mouthpiece downwards. Put the mouthpiece between your teeth and seal the lips around it. Then, press down the inhaler once to release the medication. Breathe in slowly and hold your breath for 5 to 10 seconds. Breathe out slowly. Repeat the process until you have inhaled the number of puffs prescribed by the doctor. Rinse your mouth with water and spit it out after using inhaler/Transhaler/turbuhaler to avoid fungal infections in mouth and throat. Rotacaps/Transcaps/Instacaps/Redicaps: The capsule should be placed at the base of rotahaler/transhaler/instahaler/redihaler and completely twist the mouthpiece until you hear a click sound. Then, breathe in through the mouthpiece deeply and hold your breath for 10 seconds. It is for inhalation only. Do not swallow capsule. Respules/Smartules: Check the label for directions before using it. Twist the respule/smartule top, squeeze all the liquid into the nebulizer and use immediately after opening.

Medicinal Benefits

Budamate 400 Transhaler is a combination of two drugs, namely: Budesonide and Formoterol that is used to treat symptoms of asthma and chronic obstructive pulmonary diseases (COPD). Budesonide belongs to the class of corticosteroids that works by reducing the irritation and swelling by acting inside cells of the nasal lining and stops the release of certain chemicals in the body that cause inflammatory reactions. Thereby, provides relief from sneezing, runny or blocked nose and sinus discomfort. Formoterol belongs to the class of bronchodilators that works by relaxing muscles and widening the airways of the lungs. Thus, it makes breathing easier.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Budamate 400 Transhaler

  • Fungal infection in the mouth
  • Headache
  • Sore throat, hoarse voice
  • Upper respiratory tract infection
  • Flu, cough
  • Back pain
  • Increased heart rate
  • Shaking or trembling

Drug Warnings

If you are allergic to lactose, Budamate 400 Transhaler or any other ingredients, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Budamate 400 Transhaler. Budamate 400 Transhaler is not recommended for children below 6 years of age. If your breathing worsens or you often wake up at night with asthma, experience chest tightness in the morning or lasts longer than usual, please consult a doctor immediately as these might be signs indicating that your asthma is not controlled properly and requires an alternate or additional treatment. Regular monitoring of potassium levels is recommended while taking Budamate 400 Transhaler as it may cause low potassium levels in the blood. Avoid contact with people who have infections or who are sick as Budamate 400 Transhaler may weaken the immune system causing infections easily. If you have high blood pressure, diabetes, hypokalaemia (low potassium levels in the blood), glaucoma, cataracts, osteoporosis (weak bones), fits, immune system problems, chickenpox, measles, thyroid, lung, heart, liver or adrenal gland problems, inform your doctor before taking Budamate 400 Transhaler.

Drug-Drug Interactions

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BudesonideRibociclib
Critical
BudesonideMifepristone
Critical

Drug-Drug Interactions

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BudesonideRibociclib
Critical
How does the drug interact with Budamate 400 Transhaler:
Coadministration of Budamate 400 Transhaler and Ribociclib may increase the absorption of the medication from Budamate 400 Transhaler into the blood stream.

How to manage the interaction:
Taking Ribociclib with Budamate 400 Transhaler can cause an interaction, consult a doctor before taking it. Consult a doctor if experience swelling, weight gain, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist. Do not stop using any medications without talking to a doctor.
BudesonideMifepristone
Critical
How does the drug interact with Budamate 400 Transhaler:
Using mifepristone together with Budamate 400 Transhaler may significantly reduce the effects of Budamate 400 Transhaler.

How to manage the interaction:
Taking Budamate 400 Transhaler with Mifepristone is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
FormoterolLabetalol
Severe
How does the drug interact with Budamate 400 Transhaler:
Co-administration of labetalol and Budamate 400 Transhaler together could decrease the effects of both medications.

How to manage the interaction:
Although taking Labetalol and Budamate 400 Transhaler together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
FormoterolPropranolol
Severe
How does the drug interact with Budamate 400 Transhaler:
Coadministration of propranolol with Budamate 400 Transhaler can reduce the effects of both medications.

How to manage the interaction:
Although taking propranolol and Budamate 400 Transhaler together can result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
FormoterolTimolol
Severe
How does the drug interact with Budamate 400 Transhaler:
Taking timolol with Budamate 400 Transhaler could reduce the benefits of both medications because they have opposite effects on the body.

How to manage the interaction:
Although taking Budamate 400 Transhaler and timolol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms, contact your doctor immediately. Do not stop using any medications without talking to your doctor.
FormoterolSotalol
Severe
How does the drug interact with Budamate 400 Transhaler:
Taking sotalol with Budamate 400 Transhaler could reduce the benefits of both medications because they have opposite effects on the body.

How to manage the interaction:
Although there is an interaction between Sotalol and Budamate 400 Transhaler, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
FormoterolMetipranolol
Severe
How does the drug interact with Budamate 400 Transhaler:
Using Budamate 400 Transhaler together with metipranolol can reduce the effects of both medications.

How to manage the interaction:
Although there is an interaction between Budamate 400 Transhaler and metipranolol, they can be taken together if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
FormoterolPindolol
Severe
How does the drug interact with Budamate 400 Transhaler:
Using Budamate 400 Transhaler with pindolol together could decrease the effects of both medications.

How to manage the interaction:
Although there is an interaction between Budamate 400 Transhaler and Pindolol, they can be taken together if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
FormoterolEpinephrine
Severe
How does the drug interact with Budamate 400 Transhaler:
Using epinephrine together with Budamate 400 Transhaler may increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Budamate 400 Transhaler and Epinephrine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
FormoterolPenbutolol
Severe
How does the drug interact with Budamate 400 Transhaler:
Using Budamate 400 Transhaler together with penbutolol can reduce the effect of both medications.

How to manage the interaction:
There may be a possibility of interaction between Penbutolol and Budamate 400 Transhaler, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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BUDESONIDE-400MCG+FORMOTEROL-6MCGFruit juices, Fruits
Moderate

Drug-Food Interactions

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BUDESONIDE-400MCG+FORMOTEROL-6MCGFruit juices, Fruits
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Budamate 400 Transhaler levels in your body can grow due to grapefruit, which will result in more side effects. While using Budamate 400 Transhaler, you must stay away from consuming grapefruits and grapefruit juice. In case of any unusual side effects, consult a doctor. Do not discontinue any medication without consulting a doctor.

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to strengthen your breathing muscles and boost your immune system.
  • Avoid foods such as cabbage, beans, garlic, onions, shrimp, pickled food, dried fruits, fried foods, carbonated drinks, wine, bottled lemon and lime juice as it may worsen asthma symptoms.
  • Do meditation, deep breathing, regular exercise and try progressive muscle relaxation techniques to get relief from stress and reduce the risk of an asthma attack.
  • Quit smoking as it may reduce the effectiveness of the Budamate 400 Transhaler and irritate the lungs worsening breathing problem.
  • Learning breathing exercises will help you move more air in and out of your lungs.

Habit Forming

No

Therapeutic Class

RESPIRATORY STIMULANTS

Budamate 400 Transhaler Substitute

Substitutes safety advice
  • Foracort 400 Rotacaps 30's

    by Others

    7.01per tablet
  • Foracort 400 Synchrobreathe Inhaler 120 mdi

    by AYUR

    4.09per tablet
  • Budamate 400 Transcaps 30's

    by Others

    7.01per tablet
  • Formonide 400 Inhaler 120 mdi

    by Others

    3.39per tablet
  • Formonide 400 Respicaps 30's

    by Others

    7.01per tablet

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Yes, Budamate 400 Transhaler may cause fungal infection in the mouth (oral thrush) as a common side effect. It is not necessary for everyone taking Budamate 400 Transhaler to experience this side effect. However, to avoid such side effects, brush your teeth or rinse your mouth with water after using Budamate 400 Transhaler every time.

Budamate 400 Transhaler should be used with caution in osteoporosis (low bone density resulting in weak and brittle bones) patients as it may worsen the condition. Therefore, inform your doctor if you have osteoporosis before taking Budamate 400 Transhaler so that the dose may be adjusted or an alternate medicine may be prescribed.

No, you are not recommended to take ketoconazole or other antifungal drugs such as itraconazole, posaconazole and voriconazole with Budamate 400 Transhaler as co-administration of these medicines may increase the absorption of Budamate 400 Transhaler into the bloodstream and increase the risk of adverse effects such as high blood pressure, weight gain, depression, muscle weakness, swelling, acne, skin thinning, cataracts, excessive growth of facial or body hair, stretch marks, high blood glucose levels, menstrual irregularities, loss of bone density, easy bruising and abnormal distribution of body fat, especially in the waist, back, neck and face, neck. However, please consult a doctor before using other medicines with Budamate 400 Transhaler.

You are not recommended to take more than the prescribed dose of Budamate 400 Transhaler as it may cause adverse effects such as fast heartbeat, trembling or headache. However, if you experience any of these symptoms while taking Budamate 400 Transhaler, please consult a doctor immediately.

You are not recommended to stop taking Budamate 400 Transhaler without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Budamate 400 Transhaler for as long as your doctor has prescribed it, and if you experience any difficulty while taking Budamate 400 Transhaler, please consult your doctor.

Budamate 400 Transhaler does not relieve a sudden asthma attack. Therefore, it is advised to carry a rescue inhaler always to treat sudden asthma symptoms.

Throat irritation or pain, oral thrush (fungal infection), respiratory tract infections, low potassium level and sinusitis (sinus inflammation) are some of the common side effects of Budamate 400 Transhaler, which might occur in some patients.

In rare cases, Budamate 400 Transhaler may cause low potassium level. So if you experience tiredness, muscle cramps, weakness, abnormal heart rhythms (arrhythmias) and constipation contact doctor for the advice.

People with heart problems (including high blood pressure, chest pain, fast heartbeat, fits (seizures), thyroid problems, diabetes, immune system problem, weak bones or osteoporosis, eye problems (glaucoma, cataracts) and liver problems should consult a doctor before using Budamate 400 Transhaler.

Drug-Drug Interactions Checker List

  • ALBUTEROL
  • PREDNISONE
  • FUROSEMIDE
  • ASPIRIN
  • AZITHROMYCIN
  • DULOXETINE
  • METOPROLOL
  • ITRACONAZOLE
  • KETOCONAZOLE
  • VORICONAZOLE
  • POSACONAZOLE
  • RITONAVIR

Special Advise

  • You are advised to rinse your mouth with water after each dose of Budamate 400 Transhaler because it not only removes the taste of medicine inhaled but also helps to avoid fungal infections (oral thrush) in the mouth and throat. After rinsing your mouth thoroughly, you may drink water, milk or any liquids.
  • Avoid using more than 12 inhalations in a day and more than 6 inhalations at once.

Disease/Condition Glossary

Asthma: It is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus leading to difficulty in breathing. The symptoms of asthma include wheezing (whistling sound while breathing), shortness of breath, chest tightness and cough especially at night. The symptoms of mild persistent asthma may occur more than 2 times in a week and up to 4 nights in a month whereas, in case of severe persistent asthma, the symptoms occur several times every day and most nights. The treatment for asthma includes medication, breathing exercises and self-care.

Chronic obstructive pulmonary disease (COPD): It is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes). The major cause of COPD is smoking tobacco. Also, long-term exposure to fumes and chemicals may lead to COPD. The symptoms include chronic cough, shortness of breath or wheezing (whistle sound while breathing).

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