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Written By Divya L , PharmaD
Reviewed By Sureshvarma D , MPharma

About Bupicain-0.5% Injection 20 ml

Bupicain-0.5% Injection 20 ml belongs to the class of 'local anaesthetics', primarily used to reduce pain and discomfort during labour, surgery, dental treatment and other medical procedures. It produces local numbness and relieves pain. Bupicain-0.5% Injection 20 ml is given in the form of an epidural injection at the spinal cord to prevent pain during labour and Caesarean section. Pain is a symptom triggered by the nervous system, which causes uncomfortable sensations in the body. Pain may be dull or sharp, it might be constant or intermittent. The tolerance level of pain might vary from person to person.

Bupicain-0.5% Injection 20 ml contains 'Bupivacaine' that belongs to the group of medicines called 'amide-type anaesthetics'. Bupivacaine is a numbing medication that blocks the transmission of pain signals in the pain area by acting on the nervous system and nerves. This blockage causes the loss of pain sensation and promotes temperature, touch, deep pressure and muscle control. Thus Bupicain-0.5% Injection 20 ml helps in numbing the area and provides relief from pain.

Your doctor will decide the dose and duration based on the severity of your pain and response to treatment. Common side effects of Bupicain-0.5% Injection 20 ml include weakness, numbness or tingling, restlessness, drowsiness, tremors or shakiness, headache, blurred vision, irregular heartbeat, chills or shivering, back pain, nausea and vomiting. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Inform your doctor if you have liver, kidney or heart diseases, high or low blood pressure, excess fat in the body and breathing problems before starting Bupicain-0.5% Injection 20 ml. It is essential to let your doctor know if you are pregnant, planning to conceive or a breastfeeding mother before using Bupicain-0.5% Injection 20 ml. Bupicain-0.5% Injection 20 ml causes drowsiness, so do not drive until you are mentally alert. Avoid alcohol to further prevent the worsening of side effects like drowsiness. Bupicain-0.5% Injection 20 ml is not recommended for children less than one year of age.

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Whats That

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Non returnable*
COD available

Online payment accepted

Composition

BUPIVACAINE-5MG

Consume Type

PARENTERAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of Bupicain-0.5% Injection 20 ml

Temporary pain relief.

Medicinal Benefits

Bupicain-0.5% Injection 20 ml contains 'Bupivacaine,' a local anaesthetic used to relieve pain and discomfort during labour, surgery, dental treatment and other medical procedures. It works by blocking the transmission of pain signals in the pain area by acting on the nervous system and nerves. This blockage causes the loss of pain sensation and promotes temperature, touch, deep pressure and muscle control. Thus Bupicain-0.5% Injection 20 ml helps in numbing the localized area and provides relief from pain. Bupicain-0.5% Injection 20 ml, when injected as an epidural injection at the spinal cord, it prevents pain during labour and Caesarean section.

Side Effects of Bupicain-0.5% Injection 20 ml

  • Weakness
  • Numbness or tingling
  • Restlessness
  • Drowsiness
  • Tremors or shakiness
  • Headache
  • Blurred vision
  • Irregular heartbeat
  • Hypotension
  • Chills or shivering
  • Back pain
  • Nausea
  • Vomiting 

Directions for Use

Bupicain-0.5% Injection 20 ml will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Brief your medical history to the doctor if you have any liver, kidney or heart diseases, high or low blood pressure, excess fat in the body, breathing problems, excess fluid in womb during pregnancy (a condition called hydramnios), a tumour of the ovary, blood poisoning (septicaemia) and fluid around lungs before starting Bupicain-0.5% Injection 20 ml. Let your doctor know if you use any prescription and non-prescription medications, including vitamins and herbal supplements, before starting Bupicain-0.5% Injection 20 ml. Bupicain-0.5% Injection 20 ml may affect the foetus when used by a pregnant mother. It is also released into breast milk during breastfeeding. Please consult your doctor know if you are pregnant, planning to conceive or a breastfeeding mother. Bupicain-0.5% Injection 20 ml causes dizziness and drowsiness, so do not drive until you are mentally alert. Avoid alcohol to prevent the worsening of side effects further. Bupicain-0.5% Injection 20 ml is not recommended in children younger than one year of age.

Therapeutic Class

LOCAL ANESTHETICS

Drug-Drug Interactions

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BupivacainePhenytoin
Severe
BupivacaineAmyl nitrite
Severe

Drug-Drug Interactions

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BupivacainePhenytoin
Severe
How does the drug interact with Bupicain-0.5% Injection 20 ml:
Coadministration of Phenytoin and Bupicain-0.5% Injection 20 ml can induce methemoglobinemia (a condition in which the iron in the hemoglobin molecule - the red blood pigment is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Bupicain-0.5% Injection 20 ml and phenytoin together may cause an interaction, it is safe to do so if a doctor has prescribed it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
BupivacaineAmyl nitrite
Severe
How does the drug interact with Bupicain-0.5% Injection 20 ml:
Combining Bupicain-0.5% Injection 20 ml with Amyl nitrite can increase the risk of methemoglobinemia( a rare condition that can lead to oxygen deprivation in tissues and vital organs due to reduced oxygen-carrying capacity of the blood.)

How to manage the interaction:
Taking Bupicain-0.5% Injection 20 ml with Amyl nitrite together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, call a doctor right away. Do not stop using any medications without a doctor's advice.
BupivacaineNitrofurantoin
Severe
How does the drug interact with Bupicain-0.5% Injection 20 ml:
Taking Bupicain-0.5% Injection 20 ml and Nitrofurantoin may cause methemoglobinemia, (a condition in which the iron in the hemoglobin molecule -the red blood pigment is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Taking Bupicain-0.5% Injection 20 ml and nitrofurantoin together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
BupivacaineProcaine
Severe
How does the drug interact with Bupicain-0.5% Injection 20 ml:
C0-administration of Bupicain-0.5% Injection 20 ml with procaine can have additive toxic effects, so using them together increases the risk of serious side effects like methemoglobinemia (a condition that can deprive tissues and organs of oxygen), reactions in the central nervous system (e.g-convulsions, unconsciousness, coma, respiratory arrest), and cardiovascular disorders (e.g- low blood pressure, heart block, irregular heart rhythm).

How to manage the interaction:
Co-administration of Bupicain-0.5% Injection 20 ml with Procaine can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience pale, grey, or blue-coloured skin, headache, rapid heart rate, shortness of breath, lightheadedness, or fatigue, consult a doctor. Do not stop using any medications without consulting a doctor.
BupivacaineNitric oxide
Severe
How does the drug interact with Bupicain-0.5% Injection 20 ml:
Taking Bupicain-0.5% Injection 20 ml and Nitric oxide may cause methemoglobinemia, (a condition in which the iron in the hemoglobin molecule -the red blood pigment is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Bupicain-0.5% Injection 20 ml and nitric oxide together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
BupivacaineIfosfamide
Severe
How does the drug interact with Bupicain-0.5% Injection 20 ml:
Taking Bupicain-0.5% Injection 20 ml and Ifosfamide may cause methemoglobinemia, (a condition in which the iron in the hemoglobin molecule -the red blood pigment is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Bupicain-0.5% Injection 20 ml and ifosfamide together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
BupivacainePrimaquine
Severe
How does the drug interact with Bupicain-0.5% Injection 20 ml:
Coadministration of Primaquine and Bupicain-0.5% Injection 20 ml can induce methemoglobinemia, (a condition in which the iron in the hemoglobin molecule -the red blood pigment is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Bupicain-0.5% Injection 20 ml and primaquine together may cause an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms such as gray discoloration of the skin, nausea, headache, dizziness, lightheadedness, fatigue, breathing difficulty, rapid or shallow breathing, a rapid heartbeat, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
BupivacaineSulfasalazine
Severe
How does the drug interact with Bupicain-0.5% Injection 20 ml:
Coadministration of Bupicain-0.5% Injection 20 ml and sulfasalazine may result in methemoglobinemia, an uncommon disorder that lowers the blood's ability to carry oxygen, which can induce oxygen deprivation in tissues and essential organs.

How to manage the interaction:
Although taking Bupicain-0.5% Injection 20 ml and sulfasalazine together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as grey discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
BupivacaineGlyceryl trinitrate
Severe
How does the drug interact with Bupicain-0.5% Injection 20 ml:
Coadministration of Bupicain-0.5% Injection 20 ml and glyceryl trinitrate can increase the risk and severity of developing methemoglobinemia, (Red blood cells are unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Bupicain-0.5% Injection 20 ml and glyceryl trinitrate together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
BupivacaineMetoclopramide
Severe
How does the drug interact with Bupicain-0.5% Injection 20 ml:
Coadministration of Bupicain-0.5% Injection 20 ml and Metoclopramide can increase the risk of methemoglobinemia (a condition in which the iron in the hemoglobin molecule (the red blood pigment) is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although there is a possible interaction between metoclopramide and Bupicain-0.5% Injection 20 ml, you can take these medicines together if prescribed by a doctor. However, if you experience symptoms such as grey discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • LIDOCAINE
  • AMIODARONE
  • MEXILETINE
  • ASPIRIN
  • ATENOLOL
  • BISOPROLOL

Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle exercises like 20-30 minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, apply a cold or hot compress on the painful areas for 15-20 minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listen to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Special Advise

  • Let your doctor know that you are taking Bupicain-0.5% Injection 20 ml if you are undergoing any medical tests.
  • Monitor your blood pressure regularly since Bupicain-0.5% Injection 20 ml may affect your blood pressure.

Author Details

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Disease/Condition Glossary

Pain is not a disease but a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp; it might be constant or intermittent. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific area of the body). Pain can be considered a good thing as it helps us know that something is wrong in the body and thereby helps diagnose the condition. The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures, arthritis and stomach ache.

Bupicain-0.5% Injection 20 ml Substitute

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