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Written By Divya L , PharmaD
Reviewed By Sureshvarma D , MPharma
Non returnable*
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Composition :

BUPIVACAINE-0.5%

Manufacturer/Marketer :

Themis Medicare Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About BUPICAIN INJECTION 5ML

BUPICAIN INJECTION 5ML belongs to the class of 'local anaesthetics', primarily used to reduce pain and discomfort during labour, surgery, dental treatment and other medical procedures. It produces local numbness and relieves pain. BUPICAIN INJECTION 5ML is given in the form of an epidural injection at the spinal cord to prevent pain during labour and Caesarean section. Pain is a symptom triggered by the nervous system, which causes uncomfortable sensations in the body. Pain may be dull or sharp, it might be constant or intermittent. The tolerance level of pain might vary from person to person.

BUPICAIN INJECTION 5ML contains 'Bupivacaine' that belongs to the group of medicines called 'amide-type anaesthetics'. Bupivacaine is a numbing medication that blocks the transmission of pain signals in the pain area by acting on the nervous system and nerves. This blockage causes the loss of pain sensation and promotes temperature, touch, deep pressure and muscle control. Thus BUPICAIN INJECTION 5ML helps in numbing the area and provides relief from pain.

Your doctor will decide the dose and duration based on the severity of your pain and response to treatment. Common side effects of BUPICAIN INJECTION 5ML include weakness, numbness or tingling, restlessness, drowsiness, tremors or shakiness, headache, blurred vision, irregular heartbeat, chills or shivering, back pain, nausea and vomiting. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Inform your doctor if you have liver, kidney or heart diseases, high or low blood pressure, excess fat in the body and breathing problems before starting BUPICAIN INJECTION 5ML. It is essential to let your doctor know if you are pregnant, planning to conceive or a breastfeeding mother before using BUPICAIN INJECTION 5ML. BUPICAIN INJECTION 5ML causes drowsiness, so do not drive until you are mentally alert. Avoid alcohol to further prevent the worsening of side effects like drowsiness. BUPICAIN INJECTION 5ML is not recommended for children less than one year of age.

Uses of BUPICAIN INJECTION 5ML

Temporary pain relief.

Directions for Use

BUPICAIN INJECTION 5ML will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

BUPICAIN INJECTION 5ML contains 'Bupivacaine,' a local anaesthetic used to relieve pain and discomfort during labour, surgery, dental treatment and other medical procedures. It works by blocking the transmission of pain signals in the pain area by acting on the nervous system and nerves. This blockage causes the loss of pain sensation and promotes temperature, touch, deep pressure and muscle control. Thus BUPICAIN INJECTION 5ML helps in numbing the localized area and provides relief from pain. BUPICAIN INJECTION 5ML, when injected as an epidural injection at the spinal cord, it prevents pain during labour and Caesarean section.

Storage

Store in a cool and dry place away from sunlight
Side effects of Bupicain Injection 5ml
  • Exercising regularly helps lower the risk of heart problems.
  • Maintain a healthy diet, including vegetables and fruits.
  • Rest well; get enough sleep.
  • Manage stress with yoga and meditation.
  • Limit alcohol and smoking.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Change positions or take a break from activity to relieve symptoms.
  • Avoid postures that put a lot of pressure on just one area of the body.
  • If you have vitamin deficiency, take supplements or change your diet.
  • Exercise regularly like cycling, walking or swimming.
  • Avoid sitting with your legs crossed.
  • Clench and unclench your fists and wiggle your toes.
  • Massage the affected area.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Drug Warnings

Brief your medical history to the doctor if you have any liver, kidney or heart diseases, high or low blood pressure, excess fat in the body, breathing problems, excess fluid in womb during pregnancy (a condition called hydramnios), a tumour of the ovary, blood poisoning (septicaemia) and fluid around lungs before starting BUPICAIN INJECTION 5ML. Let your doctor know if you use any prescription and non-prescription medications, including vitamins and herbal supplements, before starting BUPICAIN INJECTION 5ML. BUPICAIN INJECTION 5ML may affect the foetus when used by a pregnant mother. It is also released into breast milk during breastfeeding. Please consult your doctor know if you are pregnant, planning to conceive or a breastfeeding mother. BUPICAIN INJECTION 5ML causes dizziness and drowsiness, so do not drive until you are mentally alert. Avoid alcohol to prevent the worsening of side effects further. BUPICAIN INJECTION 5ML is not recommended in children younger than one year of age.

Drug-Drug Interactions

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BupivacaineTrimethoprim
Severe
BupivacaineLevobupivacaine
Severe

Drug-Drug Interactions

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BupivacaineTrimethoprim
Severe
How does the drug interact with Bupicain Injection 5ml:
Taking Bupicain Injection 5ml and Trimethoprim may cause methemoglobinemia, (blood disorder that affects how red blood cells deliver oxygen throughout the body).

How to manage the interaction:
Although there is an interaction between Bupicain Injection 5ml and trimethoprim, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience nausea, headache, dizziness, lightheadedness, fatigue, or shortness of breath. Do not discontinue any medications without consulting a doctor.
BupivacaineLevobupivacaine
Severe
How does the drug interact with Bupicain Injection 5ml:
C0administration of Bupicain Injection 5ml with levobupivacaine can have additive toxic effects, so using them together increases the risk of serious side effects like methemoglobinemia (a condition that can deprive tissues and organs of oxygen), reactions in the central nervous system (e.g-convulsions, unconsciousness, coma, respiratory arrest), and cardiovascular disorders (e.g- low blood pressure, heart block, irregular heart rhythm).

How to manage the interaction:
There may be a possibility of interaction between Bupicain Injection 5ml and Levobupivacaine, but it can be taken if prescribed by a doctor. However, if you experience pale, grey, or blue-coloured skin, headache, rapid heart rate, shortness of breath, lightheadedness, or fatigue, consult a doctor. Do not stop using any medications without a doctor's advice.
BupivacaineFlutamide
Severe
How does the drug interact with Bupicain Injection 5ml:
Taking Bupicain Injection 5ml and Flutamide may cause methemoglobinemia, (a condition in which the iron in the hemoglobin molecule -the red blood pigment is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Bupicain Injection 5ml and Flutamide together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
BupivacaineMexiletine
Severe
How does the drug interact with Bupicain Injection 5ml:
Taking Mexiletine with Bupicain Injection 5ml may cause serious side effects including methemoglobinemia, a serious blood disorder in which too little oxygen is delivered to your cells and heart problems.

How to manage the interaction:
Although taking Bupicain Injection 5ml and mexiletine together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor immediately if you develop pale, grey, or blue-coloured skin, abnormal blood colouration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, Jerking movements of the arms and legs, Loss of consciousness, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without talking to a doctor.
BupivacaineNitrofurantoin
Severe
How does the drug interact with Bupicain Injection 5ml:
Taking Bupicain Injection 5ml and Nitrofurantoin may cause methemoglobinemia, (a condition in which the iron in the hemoglobin molecule -the red blood pigment is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Taking Bupicain Injection 5ml and nitrofurantoin together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
BupivacainePhenazopyridine
Severe
How does the drug interact with Bupicain Injection 5ml:
Taking phenazopyridine with Bupicain Injection 5ml can increase the risk of methemoglobinemia,(a blood disorder that affects how red blood cells deliver oxygen throughout your body).

How to manage the interaction:
Although taking Bupicain Injection 5ml and phenazopyridine together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
BupivacaineRopivacaine
Severe
How does the drug interact with Bupicain Injection 5ml:
Combining Ropivacaine with Bupicain Injection 5ml can have additive toxic effects, so using them together increases the risk of serious side effects like methemoglobinemia (a condition that can deprive tissues and organs of oxygen), reactions in the central nervous system (e.g-convulsions, unconsciousness, coma, respiratory arrest), and cardiovascular disorders (e.g- low blood pressure, heart block, irregular heart rhythm).

How to manage the interaction:
Although there is a possible interaction between Ropivacaine and Bupicain Injection 5ml, you can take these medicines together if prescribed by a doctor. However, if you experience pale, grey, or blue-coloured skin, headache, rapid heart rate, shortness of breath, lightheadedness, or fatigue, consult a doctor. Do not stop using any medications without consulting a doctor.
BupivacaineNitric oxide
Severe
How does the drug interact with Bupicain Injection 5ml:
Taking Bupicain Injection 5ml and Nitric oxide may cause methemoglobinemia, (a condition in which the iron in the hemoglobin molecule -the red blood pigment is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Bupicain Injection 5ml and nitric oxide together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
BupivacainePhenytoin
Severe
How does the drug interact with Bupicain Injection 5ml:
Coadministration of Phenytoin and Bupicain Injection 5ml can induce methemoglobinemia (a condition in which the iron in the hemoglobin molecule - the red blood pigment is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Bupicain Injection 5ml and phenytoin together may cause an interaction, it is safe to do so if a doctor has prescribed it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
BupivacainePrimaquine
Severe
How does the drug interact with Bupicain Injection 5ml:
Coadministration of Primaquine and Bupicain Injection 5ml can induce methemoglobinemia, (a condition in which the iron in the hemoglobin molecule -the red blood pigment is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Bupicain Injection 5ml and primaquine together may cause an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms such as gray discoloration of the skin, nausea, headache, dizziness, lightheadedness, fatigue, breathing difficulty, rapid or shallow breathing, a rapid heartbeat, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle exercises like 20-30 minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, apply a cold or hot compress on the painful areas for 15-20 minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listen to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

LOCAL ANESTHETICS

BUPICAIN INJECTION 5ML Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

BUPICAIN INJECTION 5ML temporarily blocks the pain signals from the nerves of the painful area to the brain, thereby causing numbness at the affected site and provides relief from pain.

BUPICAIN INJECTION 5ML may affect your blood pressure. It is advised to inform your doctor before using BUPICAIN INJECTION 5ML if you have high blood pressure during pregnancy or low blood pressure.

You are recommended to consult your doctor to know the after-effects of BUPICAIN INJECTION 5ML if you are using an epidural injection of BUPICAIN INJECTION 5ML. Some epidural numbing medications may have long-lasting or permanent effects on body functions like bowel movement or bladder control, sexual function and movement in your legs. Please discuss the risks and benefits thoroughly with your doctor.

After using BUPICAIN INJECTION 5ML, you may not be able to move your body or the localized part for certain time. You may feel numbness in the injected area. When you are injected with an epidural, you may not be able to move your lower part of the body for a certain period. It is advised to stay careful during such times to avoid any injuries. After a dental procedure with the usage of BUPICAIN INJECTION 5ML, please don't eat, chew gum or drink hot beverages until your mouth is completely free of numbness.

BUPICAIN INJECTION 5ML should be used with caution and only under doctor's supervision if you have any liver, kidney or heart diseases, high or low blood pressure, excess fat in the body, breathing problems, excess fluid in womb during pregnancy (a condition called hydramnios), a tumour of the ovary, blood poisoning (septicaemia) and fluid around lungs. Please let your doctor know if you suffer from any medical issues before using BUPICAIN INJECTION 5ML.

Drug-Drug Interactions Checker List

  • LIDOCAINE
  • AMIODARONE
  • MEXILETINE
  • ASPIRIN
  • ATENOLOL
  • BISOPROLOL

Special Advise

  • Let your doctor know that you are taking BUPICAIN INJECTION 5ML if you are undergoing any medical tests.
  • Monitor your blood pressure regularly since BUPICAIN INJECTION 5ML may affect your blood pressure.

Disease/Condition Glossary

Pain is not a disease but a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp; it might be constant or intermittent. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific area of the body). Pain can be considered a good thing as it helps us know that something is wrong in the body and thereby helps diagnose the condition. The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures, arthritis and stomach ache.

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