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Not for online sale
Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Whats That

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Composition :

BUPRENORPHINE-10MG

Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

TOPICAL

Return Policy :

Not Returnable

Expires on or after :

About Bupreplast 10Mcg/Hr Transdermal Patch

Bupreplast 10Mcg/Hr Transdermal Patch belongs to a class of drugs called 'opioid analgesics' primarily used to treat, prevent and treat severe pain. Pain can be temporary (acute) or long-lasting (chronic) in nature. Acute pain is caused by damage to the tissues of the muscle, bone, or other organs for a short time. Chronic pain lasts for a long duration and is caused due to pathologies like nerve damage and osteoarthritis.

Bupreplast 10Mcg/Hr Transdermal Patch contains 'Buprenorphine', an opioid partial agonist-antagonists. It works by blocking a chemical messenger in the brain responsible for causing pain. This provides pain relief by acting on specific receptors in the brain and helps in relieving pain.

Use Bupreplast 10Mcg/Hr Transdermal Patch as advised by your doctor. You may experience certain side effects in some cases, including drowsiness, dry mouth, vomiting, blurred vision, constipation, application site reactions, dizziness or tiredness. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Bupreplast 10Mcg/Hr Transdermal Patch should be avoided if you are allergic to it or any ingredients of it or opioids. Do not use Bupreplast 10Mcg/Hr Transdermal Patch if you are pregnant or breastfeeding. Bupreplast 10Mcg/Hr Transdermal Patch is not recommended for children below 18 years of age. Bupreplast 10Mcg/Hr Transdermal Patch is a habit-forming drug; hence there is a risk of dependence. Do not stop using this medicine without consulting your doctor, as it may cause withdrawal symptoms like anxiety, increased heart rate, tremors or general unwell feelings. Bupreplast 10Mcg/Hr Transdermal Patch may decrease fertility in men and women. Do not consume alcohol while using Bupreplast 10Mcg/Hr Transdermal Patch as it may increase the risk of side effects.

Uses of Bupreplast 10Mcg/Hr Transdermal Patch

Pain

Directions for Use

Transdermal Patch: Use Bupreplast 10Mcg/Hr Transdermal Patch only as prescribed by a doctor. Do not use this medicine for a prolonged period.

Medicinal Benefits

The Bupreplast 10Mcg/Hr Transdermal Patch contains Buprenorphine. It provides pain relief by acting on specific receptors in the brain and helps in relieving pain. Compared to other opioid analgesics like methadone, Bupreplast 10Mcg/Hr Transdermal Patch has the advantage of having less sedation (sleepiness), decreased respiratory depression, decreased risk of diversion, fewer withdrawal symptoms and lower risk of toxicity at higher doses. 

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Please do not stop using Bupreplast 10Mcg/Hr Transdermal Patch suddenly, as it may cause withdrawal symptoms. Avoid frequent or high doses as it may lead to addiction. If you are known to be allergic to Bupreplast 10Mcg/Hr Transdermal Patch or any other medicines, please tell your doctor. Do not use Bupreplast 10Mcg/Hr Transdermal Patch if you are pregnant or breastfeeding, as it may cause adverse effects on the baby. Bupreplast 10Mcg/Hr Transdermal Patch is not recommended for children below 18 years of age. Avoid consuming alcohol with Bupreplast 10Mcg/Hr Transdermal Patch as it may increase the risk of side effects. Do not use this medicine if you have used an MAO inhibitor (antidepressants) in the past 14 days, as a dangerous drug interaction could occur. Bupreplast 10Mcg/Hr Transdermal Patch should be taken with extreme caution in patients who have a history of alcoholism or drug abuse. Inform your doctor if you have severe breathing problems, asthma, delirium tremens (confusion and shaking after stopping drinking alcohol), hallucinations (seeing and hearing things that are not there), kidney or liver problems, head injury or brain disease, low blood pressure, urinary disorders (especially linked to enlarged prostate), thyroid problems, adrenocortical disorder (Addison’s disease), depression or other conditions that are treated with antidepressants. 

Drug-Drug Interactions

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BuprenorphineAlvimopan
Critical
BuprenorphineZiprasidone
Critical

Drug-Drug Interactions

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BuprenorphineAlvimopan
Critical
How does the drug interact with Bupreplast 10Mcg/Hr Transdermal Patch:
Using alvimopan together with Bupreplast 10Mcg/Hr Transdermal Patch can cause side effects (abdominal pain, nausea, vomiting, and diarrhea).

How to manage the interaction:
Taking Alvimopan with Bupreplast 10Mcg/Hr Transdermal Patch is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
BuprenorphineZiprasidone
Critical
How does the drug interact with Bupreplast 10Mcg/Hr Transdermal Patch:
Taking Ziprasidone with Bupreplast 10Mcg/Hr Transdermal Patch can increase the risk of serious side effects.

How to manage the interaction:
Taking Ziprasidone with Bupreplast 10Mcg/Hr Transdermal Patch is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment. Do not discontinue any medications without consulting a doctor.
BuprenorphineChlordiazepoxide
Severe
How does the drug interact with Bupreplast 10Mcg/Hr Transdermal Patch:
Coadministration of Bupreplast 10Mcg/Hr Transdermal Patch with Chlordiazepoxide can increase the risk or severity of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.

How to manage the interaction:
Taking Bupreplast 10Mcg/Hr Transdermal Patch and chlordiazepoxide together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience drowsiness, shortness of breath, palpitations, numbness in hands and feet, or hypersensitivity to light and noise, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
BuprenorphineParamethadione
Severe
How does the drug interact with Bupreplast 10Mcg/Hr Transdermal Patch:
Using Bupreplast 10Mcg/Hr Transdermal Patch together with Paramethadione can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although there is a possible interaction between Paramethadione and Bupreplast 10Mcg/Hr Transdermal Patch, you can take these medicines together if prescribed by a doctor. Doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
BuprenorphineHydroxychloroquine
Severe
How does the drug interact with Bupreplast 10Mcg/Hr Transdermal Patch:
Taking Bupreplast 10Mcg/Hr Transdermal Patch with hydroxychloroquine increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Concomitant administration of Bupreplast 10Mcg/Hr Transdermal Patch alongside hydroxychloroquine can result in an interaction, and it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical help immediately. Do not discontinue any medications without consulting a doctor.
BuprenorphineChlorpromazine
Severe
How does the drug interact with Bupreplast 10Mcg/Hr Transdermal Patch:
Taking Bupreplast 10Mcg/Hr Transdermal Patch with chlorpromazine can increase the risk of serious side effects.

How to manage the interaction:
Taking Bupreplast 10Mcg/Hr Transdermal Patch with chlorpromazine can result in an interaction, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience unusual symptoms. Do not discontinue any medications without consulting a doctor.
BuprenorphineMoxifloxacin
Severe
How does the drug interact with Bupreplast 10Mcg/Hr Transdermal Patch:
Taking Bupreplast 10Mcg/Hr Transdermal Patch with Moxifloxacin increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Coadministration of Bupreplast 10Mcg/Hr Transdermal Patch alongside Moxifloxacin can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness, shortness of breath, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
BuprenorphineCeritinib
Severe
How does the drug interact with Bupreplast 10Mcg/Hr Transdermal Patch:
Taking ceritinib together with Bupreplast 10Mcg/Hr Transdermal Patch can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Bupreplast 10Mcg/Hr Transdermal Patch and ceritinib, but can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
BuprenorphineClomipramine
Severe
How does the drug interact with Bupreplast 10Mcg/Hr Transdermal Patch:
Using Bupreplast 10Mcg/Hr Transdermal Patch together with Clomipramine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking clomipramine and Bupreplast 10Mcg/Hr Transdermal Patch together can cause an interaction, it can be taken if a doctor has suggested it. However, contact a doctor immediately if you experience any symptoms such as confusion, hallucinations, seizures, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination. Do not discontinue any medications without consulting a doctor.
BuprenorphineDivalproex
Severe
How does the drug interact with Bupreplast 10Mcg/Hr Transdermal Patch:
Co-administration of Bupreplast 10Mcg/Hr Transdermal Patch with divalproex may increase the risk of developing side effects.

How to manage the interaction:
Co-administration of Bupreplast 10Mcg/Hr Transdermal Patch with Divalproex can result in an interaction, it can be taken when a doctor has advised it. However, if you experience shortness of breath, irregular heart rhythms, nausea, vomiting, and diarrhea contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching and low-impact aerobic exercises like walking on a treadmill, bike riding, and swimming. You can also strengthen your muscles by lifting light weights.
  • Drink plenty of water during treatment with Bupreplast 10Mcg/Hr Transdermal Patch to avoid dry mouth.
  • Maintain a fibre-rich diet and eat plenty of fresh fruits and vegetables to avoid constipation while using Bupreplast 10Mcg/Hr Transdermal Patch.
  • Avoid consumption of alcohol and quit smoking.

Habit Forming

Yes

Therapeutic Class

OPIOID ANTAGONISTS

Bupreplast 10Mcg/Hr Transdermal Patch Substitute

Substitutes safety advice
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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Bupreplast 10Mcg/Hr Transdermal Patch consists of Buprenorphine is an opioid partial agonist. It provides pain relief by acting on specific receptors in the brain that change how your body feels and responds to pain.

No, you are not recommended to take Bupreplast 10Mcg/Hr Transdermal Patch with antidepressants (medicines used to treat depression), and antipsychotics (medicines used to treat bipolar disorder and psychosis) as co-administration of these medicines with Bupreplast 10Mcg/Hr Transdermal Patch may cause life-threatening respiratory depression and death have occurred. However, please consult a doctor before taking Bupreplast 10Mcg/Hr Transdermal Patch with other medicines.

Yes, Bupreplast 10Mcg/Hr Transdermal Patch may cause withdrawal symptoms such as sweating, feeling hot and cold, runny eyes and nose, feeling or being sick, diarrhoea, stomach cramps, poor sleep, and just feeling awful. Therefore, if you experience any difficulty while using Bupreplast 10Mcg/Hr Transdermal Patch, do not stop using it suddenly and consult your doctor so that the dose may be reduced gradually to avoid withdrawal symptoms.

Yes, Bupreplast 10Mcg/Hr Transdermal Patch may cause addiction, especially if taken for a prolonged time. Therefore, Bupreplast 10Mcg/Hr Transdermal Patch should be given only for a short duration under strict medical supervision, particularly to patients susceptible to drug abuse. Take Bupreplast 10Mcg/Hr Transdermal Patch only as advised by a doctor, as overuse or misuse of Bupreplast 10Mcg/Hr Transdermal Patch can lead to overdose or death.

Drug-Drug Interactions Checker List

  • ESCITALOPRAM
  • CITALOPRAM
  • METHADONE
  • FLUOXETINE
  • DIAZEPAM
  • CODEINE
  • MORPHINE
  • AMITRIPTYLINE
  • PROMETHAZINE
  • VENLAFAXINE

Special Advise

  • Do not use Bupreplast 10Mcg/Hr Transdermal Patch for a prolonged time, as it may lead to mental or physical dependence on Bupreplast 10Mcg/Hr Transdermal Patch.
  • To avoid getting addicted to this drug, take it in prescribed quantities and as directed by your doctor. Do not self-medicate.
  • Bupreplast 10Mcg/Hr Transdermal Patch causes drowsiness. Avoid doing activities that require your complete focus and attention, like driving when on this drug.
  • An abrupt stoppage of Bupreplast 10Mcg/Hr Transdermal Patch can lead to significant withdrawal symptoms. Always discuss with your doctor about decreasing the dosage before completely stopping its usage.
  • Avoid consuming alcohol while on this medication, as it can lead to dangerous side effects.

Disease/Condition Glossary

Pain: It can be short-term (acute) or long-term (chronic) in nature. Acute pain is, for a short time, caused by damage to the tissues of the muscle, bone, or organs. Chronic pain lasts for a longer duration and is caused due to pathologies like nerve damage, osteoarthritis, and dental pain due to damage to the tooth nerve, infection, decay, extraction, or injury. Many women have painful periods known as dysmenorrhea, most often menstrual cramps. On the other hand, Osteoarthritis is a degenerative disease that results in chronic pain in joints (especially knee) and stiffness, making daily tasks difficult.

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