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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Consume Type

TOPICAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Bupreplast 5Mcg/Hr Transdermal Patch 2'S

Bupreplast 5Mcg/Hr Transdermal Patch 2'S belongs to a class of drugs called 'opioid analgesics' primarily used to treat, prevent and treat severe pain. Pain can be temporary (acute) or long-lasting (chronic) in nature. Acute pain is caused by damage to the tissues of the muscle, bone, or other organs for a short time. Chronic pain lasts for a long duration and is caused due to pathologies like nerve damage and osteoarthritis.

Bupreplast 5Mcg/Hr Transdermal Patch 2'S contains 'Buprenorphine', an opioid partial agonist-antagonists. It works by blocking a chemical messenger in the brain responsible for causing pain. This provides pain relief by acting on specific receptors in the brain and helps in relieving pain.

Use Bupreplast 5Mcg/Hr Transdermal Patch 2'S as advised by your doctor. You may experience certain side effects in some cases, including drowsiness, dry mouth, vomiting, blurred vision, constipation, application site reactions, dizziness or tiredness. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Bupreplast 5Mcg/Hr Transdermal Patch 2'S should be avoided if you are allergic to it or any ingredients of it or opioids. Do not use Bupreplast 5Mcg/Hr Transdermal Patch 2'S if you are pregnant or breastfeeding. Bupreplast 5Mcg/Hr Transdermal Patch 2'S is not recommended for children below 18 years of age. Bupreplast 5Mcg/Hr Transdermal Patch 2'S is a habit-forming drug; hence there is a risk of dependence. Do not stop using this medicine without consulting your doctor, as it may cause withdrawal symptoms like anxiety, increased heart rate, tremors or general unwell feelings. Bupreplast 5Mcg/Hr Transdermal Patch 2'S may decrease fertility in men and women. Do not consume alcohol while using Bupreplast 5Mcg/Hr Transdermal Patch 2'S as it may increase the risk of side effects.

Uses of Bupreplast 5Mcg/Hr Transdermal Patch 2'S

Pain

Directions for Use

Transdermal Patch: Use Bupreplast 5Mcg/Hr Transdermal Patch 2'S only as prescribed by a doctor. Do not use this medicine for a prolonged period.

Medicinal Benefits

The Bupreplast 5Mcg/Hr Transdermal Patch 2'S contains Buprenorphine. It provides pain relief by acting on specific receptors in the brain and helps in relieving pain. Compared to other opioid analgesics like methadone, Bupreplast 5Mcg/Hr Transdermal Patch 2'S has the advantage of having less sedation (sleepiness), decreased respiratory depression, decreased risk of diversion, fewer withdrawal symptoms and lower risk of toxicity at higher doses. 

Storage

Store in a cool and dry place away from sunlight

Side Effects of Bupreplast 5Mcg/Hr Transdermal Patch 2'S

  • Weakness
  • Anxiety
  • Nervousness
  • Dizziness
  • Headache
  • Constipation
  • Diarrhea
  • Nausea
  • Vomiting
  • Sweating
  • Application site reactions

Drug Warnings

Please do not stop using Bupreplast 5Mcg/Hr Transdermal Patch 2'S suddenly, as it may cause withdrawal symptoms. Avoid frequent or high doses as it may lead to addiction. If you are known to be allergic to Bupreplast 5Mcg/Hr Transdermal Patch 2'S or any other medicines, please tell your doctor. Do not use Bupreplast 5Mcg/Hr Transdermal Patch 2'S if you are pregnant or breastfeeding, as it may cause adverse effects on the baby. Bupreplast 5Mcg/Hr Transdermal Patch 2'S is not recommended for children below 18 years of age. Avoid consuming alcohol with Bupreplast 5Mcg/Hr Transdermal Patch 2'S as it may increase the risk of side effects. Do not use this medicine if you have used an MAO inhibitor (antidepressants) in the past 14 days, as a dangerous drug interaction could occur. Bupreplast 5Mcg/Hr Transdermal Patch 2'S should be taken with extreme caution in patients who have a history of alcoholism or drug abuse. Inform your doctor if you have severe breathing problems, asthma, delirium tremens (confusion and shaking after stopping drinking alcohol), hallucinations (seeing and hearing things that are not there), kidney or liver problems, head injury or brain disease, low blood pressure, urinary disorders (especially linked to enlarged prostate), thyroid problems, adrenocortical disorder (Addison’s disease), depression or other conditions that are treated with antidepressants. 

Drug-Drug Interactions

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BuprenorphineZiprasidone
Critical
BuprenorphineAlvimopan
Critical

Drug-Drug Interactions

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BuprenorphineZiprasidone
Critical
How does the drug interact with Bupreplast 5Mcg/Hr Transdermal Patch:
Taking Ziprasidone with Bupreplast 5Mcg/Hr Transdermal Patch can increase the risk of serious side effects.

How to manage the interaction:
Taking Ziprasidone with Bupreplast 5Mcg/Hr Transdermal Patch is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment. Do not discontinue any medications without consulting a doctor.
BuprenorphineAlvimopan
Critical
How does the drug interact with Bupreplast 5Mcg/Hr Transdermal Patch:
Using alvimopan together with Bupreplast 5Mcg/Hr Transdermal Patch can cause side effects (abdominal pain, nausea, vomiting, and diarrhea).

How to manage the interaction:
Taking Alvimopan with Bupreplast 5Mcg/Hr Transdermal Patch is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
BuprenorphinePhenobarbital
Severe
How does the drug interact with Bupreplast 5Mcg/Hr Transdermal Patch:
Using phenobarbital along with Bupreplast 5Mcg/Hr Transdermal Patch may lead to significant adverse effects (respiratory distress, and unconsciousness), and may drastically lower Bupreplast 5Mcg/Hr Transdermal Patch levels in the blood, making the medicine less effective in treating disease.

How to manage the interaction:
Although taking phenobarbital and Bupreplast 5Mcg/Hr Transdermal Patch together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience restlessness, irritability, anxiety, depression, pupil dilation, tremor, rapid heartbeat, body aches, involuntary shaking and kicking, abdominal pain, decreased hunger, nausea, vomiting, diarrhea, and weight loss, consult the doctor Do not stop using any medications without talking to a doctor.
BuprenorphinePregabalin
Severe
How does the drug interact with Bupreplast 5Mcg/Hr Transdermal Patch:
Using Pregabalin together with Bupreplast 5Mcg/Hr Transdermal Patch causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Bupreplast 5Mcg/Hr Transdermal Patch and Pregabalin together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in- judgment, reaction speed and motor coordination, consult the doctor immediately. Avoid driving or operating dangerous machinery. Do not exceed the doses, frequency, or duration of usage advised by the doctor. Do not discontinue any medications without consulting a doctor.
BuprenorphineTapentadol
Severe
How does the drug interact with Bupreplast 5Mcg/Hr Transdermal Patch:
Using Tapentadol together with Bupreplast 5Mcg/Hr Transdermal Patch can increase the risk or severity of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.

How to manage the interaction:
Taking Bupreplast 5Mcg/Hr Transdermal Patch with Tapentadol can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience signs such as drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not discontinue any medications without consulting a doctor.
BuprenorphineTrimethadione
Severe
How does the drug interact with Bupreplast 5Mcg/Hr Transdermal Patch:
When Bupreplast 5Mcg/Hr Transdermal Patch is used with trimethadione, it may lead to significant adverse effects such as respiratory difficulties, unconsciousness.

How to manage the interaction:
Concomitant administration of Bupreplast 5Mcg/Hr Transdermal Patch alongside trimethadione can result in an interaction, it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. You should avoid driving or operating hazardous machinery until you're aware of how these medications effect you. Do not discontinue any medications without consulting a doctor.
BuprenorphineGabapentin
Severe
How does the drug interact with Bupreplast 5Mcg/Hr Transdermal Patch:
Co-administration of Bupreplast 5Mcg/Hr Transdermal Patch and Gabapentin may cause central nervous system depression and lead to serious side effects (respiratory distress -build-up of fluid in the air sacs of the lungs).

How to manage the interaction:
Although there is a possible interaction between Gabapentin and Bupreplast 5Mcg/Hr Transdermal Patch, you can take these medicines together if prescribed by a doctor. However, if you experience shortness of breath, fast heart rate, fast breathing, extreme tiredness, fever, cough with phlegm, or shallow breaths, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
BuprenorphineChlorpromazine
Severe
How does the drug interact with Bupreplast 5Mcg/Hr Transdermal Patch:
Taking Bupreplast 5Mcg/Hr Transdermal Patch with chlorpromazine can increase the risk of serious side effects.

How to manage the interaction:
Taking Bupreplast 5Mcg/Hr Transdermal Patch with chlorpromazine can result in an interaction, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience unusual symptoms. Do not discontinue any medications without consulting a doctor.
BuprenorphineAlprazolam
Severe
How does the drug interact with Bupreplast 5Mcg/Hr Transdermal Patch:
Using Alprazolam together with Bupreplast 5Mcg/Hr Transdermal Patch can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although the combination of Alprazolam and Bupreplast 5Mcg/Hr Transdermal Patch may cause an interaction, they can be used if prescribed by a doctor. Consult a doctor if you have any symptoms such as dizziness, drowsiness, difficulty concentrating, or impairment in judgment, reaction speed, or control of movements. Do not discontinue any medications without consulting a doctor.
BuprenorphineCitalopram
Severe
How does the drug interact with Bupreplast 5Mcg/Hr Transdermal Patch:
Taking Bupreplast 5Mcg/Hr Transdermal Patch with citalopram increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Concomitant administration of Bupreplast 5Mcg/Hr Transdermal Patch alongside citalopram can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical help immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching and low-impact aerobic exercises like walking on a treadmill, bike riding, and swimming. You can also strengthen your muscles by lifting light weights.
  • Drink plenty of water during treatment with Bupreplast 5Mcg/Hr Transdermal Patch 2'S to avoid dry mouth.
  • Maintain a fibre-rich diet and eat plenty of fresh fruits and vegetables to avoid constipation while using Bupreplast 5Mcg/Hr Transdermal Patch 2'S.
  • Avoid consumption of alcohol and quit smoking.

Habit Forming

Yes

Therapeutic Class

OPIOID ANTAGONISTS

Bupreplast 5Mcg/Hr Transdermal Patch 2'S Substitute

Substitutes safety advice
  • Zuprinor 5 Transdermal Patch 1's

    by Others

    539.10per tablet
  • Buvalor 5 mcg/h Transdermal Patch 2's

    by AYUR

    391.05per tablet
  • Buprigesic 5mcg/Hr Transdermal Patch 2's

    by AYUR

    682.20per tablet

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ESCITALOPRAM
  • CITALOPRAM
  • METHADONE
  • FLUOXETINE
  • DIAZEPAM
  • CODEINE
  • MORPHINE
  • AMITRIPTYLINE
  • PROMETHAZINE
  • VENLAFAXINE

Special Advise

  • Do not use Bupreplast 5Mcg/Hr Transdermal Patch 2'S for a prolonged time, as it may lead to mental or physical dependence on Bupreplast 5Mcg/Hr Transdermal Patch 2'S.
  • To avoid getting addicted to this drug, take it in prescribed quantities and as directed by your doctor. Do not self-medicate.
  • Bupreplast 5Mcg/Hr Transdermal Patch 2'S causes drowsiness. Avoid doing activities that require your complete focus and attention, like driving when on this drug.
  • An abrupt stoppage of Bupreplast 5Mcg/Hr Transdermal Patch 2'S can lead to significant withdrawal symptoms. Always discuss with your doctor about decreasing the dosage before completely stopping its usage.
  • Avoid consuming alcohol while on this medication, as it can lead to dangerous side effects.

Disease/Condition Glossary

Pain: It can be short-term (acute) or long-term (chronic) in nature. Acute pain is, for a short time, caused by damage to the tissues of the muscle, bone, or organs. Chronic pain lasts for a longer duration and is caused due to pathologies like nerve damage, osteoarthritis, and dental pain due to damage to the tooth nerve, infection, decay, extraction, or injury. Many women have painful periods known as dysmenorrhea, most often menstrual cramps. On the other hand, Osteoarthritis is a degenerative disease that results in chronic pain in joints (especially knee) and stiffness, making daily tasks difficult.

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