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Written By Divya L , PharmaD
Reviewed By Sunny S , MBBS
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Composition :

BUTORPHANOL-1MG

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Butodol Injection 1 ml

Butodol Injection 1 ml belongs to the class of 'narcotic analgesics' primarily used to treat moderate to severe pain post-surgery, muscle pain, and migraine-related headaches. Butodol Injection 1 ml is also used as an anaesthesia adjunct during surgery and early labor. Pain is a symptom triggered by the nervous system, which causes uncomfortable sensations in the body. 

Butodol Injection 1 ml contains 'Butorphanol' which works by blocking the transmission of pain signals located in the brain that controls pain, pleasure, and addictive behaviors. Butorphanol also acts as a pre-anaesthetic during surgery, antitussive (cough suppressant), and antiemetic (prevents vomiting) medication.

Use this medicine as prescribed by your doctor. Your doctor will decide the dose and duration based on the severity of your pain and response to treatment. Common side effects of Butodol Injection 1 ml include headache, dizziness, sleepiness, vomiting, nausea, and constipation. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Inform your doctor beforehand if you have liver, kidney, or heart diseases, breathing problems, mood disorders, brain-related problems, gastrointestinal disorders, underactive thyroid (hypothyroidism), drug addiction, and urination problems before starting Butodol Injection 1 ml. It is essential to let your doctor know if you are pregnant, planning to conceive, or a breastfeeding mother. Butodol Injection 1 ml causes dizziness and drowsiness, so do not drive or operate machinery until you are mentally alert. Avoid alcohol to further prevent the worsening of side effects. Butodol Injection 1 ml is not recommended for people below 18 years of age.

Uses of Butodol Injection 1 ml

Pain relief.

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Butodol Injection 1 ml contains 'Butorphanol', an opioid analgesic that helps relieve moderate to severe pain post-surgery, muscle pain and migraine headaches. Butodol Injection 1 ml is also used as a part of anaesthesia during surgery and early labor. It helps relieve pain in various conditions like toothache, rheumatoid arthritis, and osteoarthritis. It works by acting on the opioid receptors and blocking the transmission of pain signals.

Storage

Store in a cool and dry place away from sunlight
Side effects of Butodol Injection 1 ml
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • A blocked nose can be relieved by drinking more water, which helps clear fluids.
  • Use saline nasal spray available over the counter to relieve blockage or blow harder to remove the mucus.
  • Use nasal strips that can be placed on the nose to widen nostrils and increase airflow.
  • Keep a humidifier around to moisten air at home/workplace.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

Drug Warnings

Inform your doctor if you have a history of liver, kidney or heart diseases, abdominal problems (gallbladder disease, pancreatitis), adrenal gland diseases (Addison's disease), brain disorders (fits, tumours, increased intracranial pressure), heart problems (irregular heartbeat, chest pain, a recent history of heart attack), high blood pressure and breathing problems (asthma, chronic obstructive pulmonary disease-COPD, sleep apnoea) before starting Butodol Injection 1 ml. If you have any mood disorders (toxic psychosis), spine problems (kyphoscoliosis), gastrointestinal problems (diarrhoea, paralytic ileus), personal or a family history of a substance use disorder like overuse of or addiction to drugs or alcohol, urination problems (enlarged prostate or urethral stricture) and an underactive thyroid (hypothyroidism), inform your doctor in advance before starting Butodol Injection 1 ml. Please consult your doctor if you are pregnant, planning to conceive or a breastfeeding mother. Butodol Injection 1 ml causes dizziness and drowsiness, so do not drive until you are mentally alert. Avoid alcohol to prevent the worsening of side effects further. Butodol Injection 1 ml is not recommended for anyone below 18 years of age.

Drug-Drug Interactions

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ButorphanolGabapentin
Severe
ButorphanolFosaprepitant
Severe

Drug-Drug Interactions

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ButorphanolGabapentin
Severe
How does the drug interact with Butodol Injection 1 ml:
Co-administration of Butodol Injection 1 ml and Gabapentin may cause central nervous system depression and lead to serious side effects such as respiratory distress (build-up of fluid in the air sacs of the lungs).

How to manage the interaction:
Although there is a possible interaction between Gabapentin and Butodol Injection 1 ml, you can take these medicines together if prescribed by a doctor. However, if you experience shortness of breath, fast heart rate, fast breathing, extreme tiredness, fever, cough with phlegm, or shallow breaths, please consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
ButorphanolFosaprepitant
Severe
How does the drug interact with Butodol Injection 1 ml:
Coadministration of Fosaprepitant with Butodol Injection 1 ml can reduce the metabolism and increase the levels of Ivabradine in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Co-administration of Fosaprepitant with Butodol Injection 1 ml can result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms like dizziness, confusion, faintness, tiredness, irregular heartbeat, trouble breathing, feeling lightheaded, trouble focusing, or having trouble breathing make sure to call a doctor right away. Do not stop using any medications without a doctor's advice.
ButorphanolFluconazole
Severe
How does the drug interact with Butodol Injection 1 ml:
Co-administration of Butodol Injection 1 ml with Fluconazole may increase the blood levels of Butodol Injection 1 ml and may increase side effects.

How to manage the interaction:
Although there is a possible interaction between Fluconazole and Butodol Injection 1 ml, you can take these medicines together if prescribed by a doctor. If you notice any symptoms like feeling tired, dizzy, or having trouble breathing, it's important to call a doctor right away. Do not stop using any medications without talking to a doctor.
ButorphanolMorphine
Severe
How does the drug interact with Butodol Injection 1 ml:
Using Morphine together with Butodol Injection 1 ml can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Co-administration of Morphine with Butodol Injection 1 ml can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, or poor speed and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.
ButorphanolNevirapine
Severe
How does the drug interact with Butodol Injection 1 ml:
When Butodol Injection 1 ml is taken with Nevirapine may reduce the blood levels of Butodol Injection 1 ml. This can lead to low treatment outcomes.

How to manage the interaction:
Although taking Nevirapine and Butodol Injection 1 ml together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience watery eyes, runny nose, sneezing, yawning, excessive sweating, goose bumps, fever, chills, flushing, restlessness, irritability, anxiety, depression, pupil dilation, tremor, rapid heartbeat, body aches, involuntary twitching and kicking, abdominal cramping, loss of appetite, nausea, vomiting, diarrhea, and weight loss call a doctor right away. Do not discontinue any medications without consulting a doctor.
ButorphanolFentanyl
Severe
How does the drug interact with Butodol Injection 1 ml:
Taking fentanyl and Butodol Injection 1 ml together can increase the risk of side effects.

How to manage the interaction:
Although taking Fentanyl together with Butodol Injection 1 ml can result in an interaction, they can be taken together if prescribed by your doctor. Do not stop using any medications without talking to your doctor.
ButorphanolOxazepam
Severe
How does the drug interact with Butodol Injection 1 ml:
Combining Oxazepam with Butodol Injection 1 ml can increase the risk of CNS depression.

How to manage the interaction:
Although taking Oxazepam and Butodol Injection 1 ml together can evidently cause an interaction, it can be taken if your doctor has suggested it. Contact your doctor immediately if you notice any symptoms like dizziness, drowsiness, difficulty concentrating, impaired judgment, reduced reaction speed, and motor coordination. Avoid driving or operating hazardous machinery until you know how it affects you, and avoid self-medication. Do not discontinue any medications without consulting your doctor.
ButorphanolZolpidem
Severe
How does the drug interact with Butodol Injection 1 ml:
Using Zolpidem together with Butodol Injection 1 ml can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Butodol Injection 1 ml and Zolpidem together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment, or reaction speed, avoid driving or operating hazardous machinery consult a doctor. Do not stop using any medications without a doctor's advice.
ButorphanolVoriconazole
Severe
How does the drug interact with Butodol Injection 1 ml:
Taking Butodol Injection 1 ml with Voriconazole may significantly increase the blood levels of Butodol Injection 1 ml which increases risk of side effects.

How to manage the interaction:
Although taking Butodol Injection 1 ml and Voriconazole together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience dizziness, or difficulty concentrating consult a doctor. Do not stop using any medications without consulting a doctor.
ButorphanolChloramphenicol
Severe
How does the drug interact with Butodol Injection 1 ml:
Taking Chloramphenicol and Butodol Injection 1 ml can significantly increase the blood levels of Butodol Injection 1 ml that may increase the risk of side effects.

How to manage the interaction:
Although taking Chloramphenicol with Butodol Injection 1 ml can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience dizziness, lightheadedness, headache, flushing, fainting, and heart palpitations feeling tired, having trouble moving, difficulty swallowing or having seizures contact your doctor know. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle exercises like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listen to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

Yes

Therapeutic Class

OPIOID ANALGESIC AND ANESTHESIA ADJUNCT

Butodol Injection 1 ml Substitute

Substitutes safety advice
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    35.10per tablet

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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FAQs

Butodol Injection 1 ml contains 'Butorphanol', an opioid pain reliever that blocks the transmission of pain signals by acting on specific centres of the brain. Thus Butodol Injection 1 ml reduces pain associated with various conditions like surgery pain, muscle pain, migraine headaches, arthritis pain and toothache.

Butodol Injection 1 ml may cause your blood pressure to drop upon administration of nasal spray. This may lead to fainting, light-headedness and dizziness after its use in the first hour. To prevent this from happening, remain sitting or lying down after using Butodol Injection 1 ml.

It is not recommended to suddenly stop taking Butodol Injection 1 ml since it may produce withdrawal symptoms, especially when you used Butodol Injection 1 ml for a longer time or in high doses. Please seek medical advice on how to stop taking Butodol Injection 1 ml safely. Your doctor may lower your dose slowly to prevent withdrawal symptoms.

Butodol Injection 1 ml can cause side effects like dizziness and drowsiness, hence it is advised to remain sitting or lying after taking Butodol Injection 1 ml. You are also advised not to drive or operate machinery until you are mentally alert.

Butodol Injection 1 ml may sometimes cause addiction despite its medical benefits. The risk of habit-forming or addiction is higher in people with a history of substance use disorder like overuse of drugs and alcohol. It is strictly recommended to use Butodol Injection 1 ml in the dose and duration prescribed by your doctor. Do not double the dose.

Drug-Drug Interactions Checker List

  • OXYMETAZOLINE
  • CODEINE
  • HYDROCODONE
  • ALPRAZOLAM
  • CYCLOBENZAPRINE
  • CETIRIZINE
  • DIPHENHYDRAMINE
  • KETOCONAZOLE
  • ERYTHROMYCIN
  • RITONAVIR
  • CLONAZEPAM
  • PHENYTOIN
  • METHYLENE BLUE
  • PROCARBAZINE
  • PHENELZINE
  • SELEGILINE
  • RASAGILINE
  • NALTREXONE

Special Advise

  • Let your doctor know that you are taking Butodol Injection 1 ml if you are undergoing any medical tests.
  • Monitor your blood pressure regularly since Butodol Injection 1 ml may affect your blood pressure.
  • Butodol Injection 1 ml may interfere with lab tests of amylase and lipase, hence inform your laboratory staff in advance that you are taking Butodol Injection 1 ml.

Disease/Condition Glossary

Pain: It is not a disease but a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp, it might be constant or may come and go. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific area of the body). Pain can be considered a good thing as it helps us know that something is wrong in the body and thereby helps diagnose the condition. The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures, arthritis and stomach ache. 

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