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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

About Cabotres 20 mg Tablet 30's

Cabotres 20 mg Tablet 30's is an anti-cancer medicine used in the treatment of renal cell carcinoma. It is a disease in which cancer cells grow uncontrollably in the kidney and form a tumor. Cabotres 20 mg Tablet 30's is used in treating advanced renal cell carcinoma as first-line therapy for advanced renal cell carcinoma in combination with nivolumab and hepatocellular carcinoma in patients who have previously been treated with sorafenib.

Cabotres 20 mg Tablet 30's contains Cabozantinib as an active ingredient, which belongs to the class of medicines known as kinase inhibitors. It works by inhibiting the action of an enzyme (tyrosine kinase) and thus stops the abnormal growth of cancer cells.

Cabotres 20 mg Tablet 30's may cause certain side effects such as diarrhea, decreased appetite, nausea, vomiting, increased blood pressure, muscle cramps, decreased weight, dizziness, and constipation. Inform your doctor if any of these side effects bother you. Cabotres 20 mg Tablet 30's should be taken as advised by your doctor.

Avoid taking Cabotres 20 mg Tablet 30's if you are allergic to it or any other components of it. Before taking Cabotres 20 mg Tablet 30's, inform your doctor if you have/had liver or kidney disease, gastrointestinal disorders, heart problems, blood or bleeding disorders, open or healing wounds, and a history of recent surgery. This medicine is known to cause embryo-fetal toxicity. Hence, it is not recommended for use in pregnancy and breastfeeding.

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Non returnable*
COD available

Online payment accepted

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

Uses of Cabotres 20 mg Tablet 30's

Renal Cell Carcinoma, Hepatocellular carcinoma.

Medicinal Benefits

Cabotres 20 mg Tablet 30's contains Cabozantinib, which is used in treating advanced renal cell carcinoma and liver cancer. It works by stopping the action of a tyrosine kinase enzyme that causes the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body. It also decreases the blood supply to cancer tumors to slow down the growth of the tumor.  In this way, Cabotres 20 mg Tablet 30's stops the body's production, spread and growth of cancerous cells.

Side Effects of Cabotres 20 mg Tablet 30's

  • Nausea
  • Vomiting
  • Diarrhoea
  • Loss of appetite
  • Increased blood pressure
  • Tiredness
  • Chest pain
  • Dizziness
  • Weakness
  • Difficulty speaking
  • Muscle pain
  • Cough
  • Shortness of breath

Directions for Use

Take Cabotres 20 mg Tablet 30's as prescribed by the doctor. It should be taken at least one hour before food or 2 hours after food. Swallow it as a whole with a glass of water. Do not crush, break, or chew the medicine. Avoid taking more than the prescribed dose of medicine.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

To treat your condition effectually, continue taking Cabotres 20 mg Tablet 30's for the period that your doctor has prescribed. Caution should be exercised if you have/had liver or kidney disease, any planned surgery, heart disease, blood or bleeding disorders, open/healing of wound, or gastrointestinal disorders. Inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment, as this medicine is known to cause embryo-fetal toxicity. Cabotres 20 mg Tablet 30's may cause hypertension, thrombotic events, hemorrhagic events, gastrointestinal perforation and fistula, Reversible Posterior Leukoencephalopathy Syndrome (RPLS), hepatotoxicity, severe diarrhoea, Osteonecrosis of the jaw (ONJ), Palmar-Plantar Erythrodysesthesia (PPE), adrenal insufficiency, impaired wound healing, and proteinuria in some patients. Hence, inform your doctor about your complete medication and medical history before taking Cabotres 20 mg Tablet 30's. Breastfeeding should be discontinued in nursing mothers during the treatment as it passes into breast milk and may cause a possible risk to the infant. Avoid driving and operating machines, as this medicine may cause dizziness. This medicine is not recommended for use in children below 18 years of age as the safety and efficacy are not established.

Therapeutic Class

ANTINEOPLASTIC

Drug-Drug Interactions

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CabozantinibAzithromycin
Severe
CabozantinibIbrutinib
Severe

Drug-Drug Interactions

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CabozantinibAzithromycin
Severe
How does the drug interact with Cabotres 20 mg Tablet 30's:
Taking azithromycin with cabozantinb may increase the risk of an abnormal heart rhythm.

How to manage the interaction:
Although using azithromycin alongside cabozantinb can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
CabozantinibIbrutinib
Severe
How does the drug interact with Cabotres 20 mg Tablet 30's:
Co-administration of Ibrutinib with Cabotres 20 mg Tablet 30's can increase the risk of bleeding and hemorrhage.

How to manage the interaction:
Taking Ibrutinib with Cabotres 20 mg Tablet 30's together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
CabozantinibErythromycin
Severe
How does the drug interact with Cabotres 20 mg Tablet 30's:
Taking Cabotres 20 mg Tablet 30's together with erythromycin increases the risk of an irregular heart rhythm.

How to manage the interaction:
Although taking Erythromycin and Cabotres 20 mg Tablet 30's together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you notice any symptoms like dizziness, fainting, irregular heart rhythm, diarrhea, or vomiting, contact your doctor right away. Do not stop using any medications without talking to your doctor.
CabozantinibAtomoxetine
Severe
How does the drug interact with Cabotres 20 mg Tablet 30's:
Taking Atomoxetine with Cabotres 20 mg Tablet 30's can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Co-administration of Atomoxetine with Cabotres 20 mg Tablet 30's can result in an interaction, but it can be taken if a doctor has advised it. However, if you notice any irregular heart rhythm, heart problems, or other symptoms like diarrhea, dizziness, or shortness of breath, call a doctor right away. Do not stop using any medications without a doctor's advice.
CabozantinibKetorolac
Severe
How does the drug interact with Cabotres 20 mg Tablet 30's:
Using Cabotres 20 mg Tablet 30's together with ketorolac may increase the risk of bleeding.

How to manage the interaction:
Taking Ketorolac with Cabotres 20 mg Tablet 30's together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience bleeding, problems, bruising, feeling dizzy or lightheaded, having red or black, sticky stools, severe headache, weakness, bleeding or vomiting contact your doctor right away. Do not stop using any medications without a doctor's advice.
CabozantinibOfloxacin
Severe
How does the drug interact with Cabotres 20 mg Tablet 30's:
Coadministration of amisulpride together with ofloxacin may raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Despite the fact that Ofloxacin and Amisulpride interact, they can be used if prescribed by a doctor. Consult a doctor if you have sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
CabozantinibApixaban
Severe
How does the drug interact with Cabotres 20 mg Tablet 30's:
Coadministration of Cabotres 20 mg Tablet 30's and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Cabotres 20 mg Tablet 30's and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
CabozantinibDasatinib
Severe
How does the drug interact with Cabotres 20 mg Tablet 30's:
Using Cabotres 20 mg Tablet 30's together with Dasatinib can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Dasatinib with Cabotres 20 mg Tablet 30's can result in an interaction, but it can be taken if a doctor has advised it. Call a doctor immediately if you notice any of these symptoms - dizziness, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
CabozantinibIbuprofen
Severe
How does the drug interact with Cabotres 20 mg Tablet 30's:
The combined use of Cabotres 20 mg Tablet 30's and Ibuprofen can increase the risk of bleeding.

How to manage the interaction:
using Cabotres 20 mg Tablet 30's and Ibuprofen can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black tarry stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
CabozantinibArtesunate
Severe
How does the drug interact with Cabotres 20 mg Tablet 30's:
Taking Artesunate with Cabotres 20 mg Tablet 30's may increase blood levels and effects of artesunate and increase the risk of side effects.

How to manage the interaction:
Although taking artesunate with Cabotres 20 mg Tablet 30's together can result in an interaction, they can be taken if a doctor has prescribed it. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CLARITHROMYCIN
  • RITONAVIR
  • ITRACONAZOLE
  • KETOCONAZOLE
  • DILTIAZEM
  • ERYTHROMYCIN
  • CARBAMAZEPINE
  • PHENYTOIN
  • PHENOBARBITAL
  • RIFAMPICIN

Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles, reduces fatigue, helps in weight loss, and gives strength. Gentle activities like 20-30 minutes of walking or swimming would be helpful.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Getting adequate sleep as resting helps improve your health and mental ability and improves attention.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
  • Eat food rich in antioxidants such as berries, spinach, etc.
  • Foods containing fibre help in better digestion. These include beans, peas, lentils, whole grains, nuts, and seeds.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight.

Habit Forming

No

Special Advise

  • Your doctor may suggest periodic liver function tests, kidney function tests, and urine tests to monitor the function of the liver kidney and the presence of protein in urine due to the use of Cabotres 20 mg Tablet 30's.
  • Seek medical attention immediately if you have swelling in your lower legs, fast heartbeats, or trouble breathing, as it may be a sign of a heart problem.
  • It is advised to use effective contraceptive methods while using Cabotres 20 mg Tablet 30's to prevent pregnancy.

Disease/Condition Glossary

Renal Cell Carcinoma: Also known as kidney cancer. It is the most common type of cancer seen in adults. This condition occurs when cancer/ malignant cells grow uncontrollably in the kidney and form a tumor. Advanced kidney cancer (metastatic renal cell carcinoma) occurs when the malignant cells spread to other parts of the body. Symptoms include red, orange, or pink-coloured urine due to the presence of blood in the urine.

Hepatocellular carcinoma: Also known as liver cancer. It occurs when the cancer/ malignant cells grow out of control. This infects the liver, destroys the liver cells and affects the ability of the liver to work properly. Symptoms may include abdominal pain, loss of appetite, weight loss, and pale bowel motions.

Cabotres 20 mg Tablet 30's Substitute

Substitutes safety advice
  • Cazanat 20 Tablet 30's

    133.93per tablet
  • Cabotib 20 mg Tablet 30's

    133.93per tablet
  • Cabolong 20 mg Tablet 30's

    198.99per tablet
  • Cabdual-20 Tablet 30's

    136.53per tablet
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