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  3. Calcium Folinate Injection 5 ml

Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Whats That

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Synonym :

LEUCOVORIN

Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Calcium Folinate Injection 5 ml

Calcium Folinate Injection 5 ml belongs to the class of medicines known as detoxifying agents or folic acid analogues used in cancer treatment as an antidote to reduce the toxic effects of certain cancer drugs, such as methotrexate. Besides this, it can also use in combination with 5-fluorouracil in cancer treatment (cytotoxic therapy).

Calcium Folinate Injection 5 ml contains calcium folinate, also known as Leucovorin, which is a form of vitamin B. It is folic acid in its active form. Calcium Folinate Injection 5 ml works by preventing healthy cells from the toxic effects of methotrexate (cancer medicines) while accepting it to enter and kill the cancer cells. It should be administered as soon as possible after taking methotrexate.

Calcium Folinate Injection 5 ml will be administered by a qualified healthcare professional. You may experience nausea, diarrhoea, rash, vomiting, itching, urticaria or hives and stomatitis (oral mucositis). Most of these side effects of Calcium Folinate Injection 5 ml do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.

Before taking the Calcium Folinate Injection 5 ml, let your doctor know if you are allergic to any ingredient in it. Inform your doctor about your medical history and other medications you are currently taking to rule out any potential negative effects. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding or if you have pernicious anaemia or other forms of megaloblastic anaemia caused by vitamin B12 deficiency, GI toxicity, renal impairment and seizures.

Uses of Calcium Folinate Injection 5 ml

Prevention of harmful effects of methotrexate

Directions for Use

Calcium Folinate Injection 5 ml will be administered by a qualified healthcare professional.

Medicinal Benefits

Calcium Folinate Injection 5 ml belongs to the class of medicines known as detoxifying agents or folic acid analogues used in cytotoxic therapy as an antidote to reduce the toxicity and effect of certain cancer drugs such as methotrexate. Calcium Folinate Injection 5 ml works by preventing healthy cells from the toxic effects of methotrexate (or other cancer medicines) while accepting it to enter and kill the cancer cells. Besides this, it can also use in combination with the drug 5-fluorouracil in cancer treatment (cytotoxic therapy).

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Before taking the Calcium Folinate Injection 5 ml, inform your doctor if you are allergic to any of its ingredients. If you are pregnant, planning to become pregnant, or breastfeeding, or if you have pernicious anaemia or other kinds of megaloblastic anaemia caused by vitamin B12 deficiency, GI toxicity, renal impairment, or seizures, please notify your doctor. And also, inform your doctor about your medical history and current drugs to rule out potential side effects.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Calcium Folinate Injection 5 ml Injection 5 ml:
Co-administration of Calcium Folinate Injection 5 ml with Trimethoprim may increase rates of treatment failure.

How to manage the interaction:
Although there is an interaction between Calcium Folinate Injection 5 ml and trimethoprim, but it can be taken together if prescribed by the doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Cancer can take a toll on anyone. Make sure you regularly see a therapist and take care of your mental health.
  • Meditation and yoga have also proven very effective in helping cancer patients maintain a healthy attitude and body.
  • Eat lean meats, healthy fats, fruits, vegetables and whole-grain foods to give you more energy. 
  • Stay hydrated by drinking plenty of water, as dehydration is often seen in cancers.
  • Taking a stroll in the garden or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired. 
  • Avoid taking Calcium Folinate Injection 5 ml with alcohol as there may be an interaction.
  • Avoid tobacco use.

Habit Forming

No

Therapeutic Class

DETOXIFYING AGENTS

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Drug-Drug Interactions Checker List

  • FLUOROURACIL
  • CAPECITABINE
  • PAFOLACIANINE
  • TRIMETHOPRIM
  • CEFTRIAXONE

Disease/Condition Glossary

Harmful effects of methotrexate: Methotrexate treats cancer, severe rheumatoid arthritis, and severe psoriasis. It can cause side effects like swollen gums, headaches, hair loss, dizziness, etc. Infrequently, it can cause fatal side effects. Harmful effects of methotrexate include vision loss, seizures/ fits, loss of consciousness, etc. It can damage the blood, liver, bone marrow, lungs, etc. The drug can lead to birth defects and death in unborn babies.

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