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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Whats That

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Composition :

CANGRELOR-50MG

Manufacturer/Marketer :

Msn Laboratories Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Canreal Injection

Canreal Injection belongs to the group of medicines called 'antiplatelet agents' used to prevent the formation of blood clots, thereby reducing the chance of Myocardial infarction. Canreal Injection is used during percutaneous coronary intervention (PCI) procedure to reduce the chance of blood clot formation.

Canreal Injection contains Cangrelor, which works by inhibiting the clumping of platelets, thereby reducing the chance of blood clot formation. This results in lower cardiovascular events like myocardial infarction (heart attack), repeat coronary revascularization, and stent thrombosis (ST).

Canreal Injection will be administered by your doctor. So, do not self-administer. The dose of the medicine will be decided by your doctor based on your health condition. Canreal Injection may cause certain side effects such as nose bleeds, skin rash, bleeding in the bowels, blood in urine, low haemoglobin, indigestion and bruising. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

Canreal Injection should not be used if you ever had a brain stroke, bleeding in the brain or transient ischemic attack (stroke). Talk to your doctor before receiving Canreal Injection, have/had a recent severe injury or surgery due to risk of severe bleeding problems. If you are pregnant or breastfeeding, inform your doctor before receiving this medicine. Canreal Injection is not recommended for children as efficacy and safety have not been established.

Uses of Canreal Injection

Myocardial infarction (heart attack)

Directions for Use

A trained healthcare professional will administer Canreal Injection. Hence do not self-administer.

Medicinal Benefits

Canreal Injection belongs to the group of medicines called antiplatelet agents (P2Y12 platelet inhibitors) used to prevent the formation of blood clots. Canreal Injection helps in reducing the chance of having a myocardial infarction (heart attack), repeat coronary revascularization, and stent thrombosis (ST). Canreal Injection works by inhibiting the clumping of platelets, thereby reducing the chance of blood clot formation. This helps in reducing the rate of cardiovascular events such as myocardial infarction (heart attack) or stroke, especially in people who have had heart surgery, known as angioplasty.

Storage

Store in a cool and dry place away from sunlight
Side effects of Canreal Injection
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
  • Apply an ice pack to slow bleeding and reduce swelling.
  • Keep your head raised to help blood drain away from your eye.
  • Take rest and avoid intense activities that raise pressure in the eye.
  • If the bleeding is severe or does not improve within 24 hours, consult a doctor.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Drug Warnings

Do not receive Canreal Injection if you are allergic to it or if you have a medical condition that causes bleeding from the stomach or intestine, had a transient ischemic attack (stroke) or if you are suffering from severe liver disease. Let your doctor know if you have bleeding problems, had/have a recent serious injury or surgery, or kidney or liver disease before receiving this medicine. Consult your doctor immediately if you develop a medical condition called thrombotic thrombocytopenic purpura (blood disorder) while on treatment with Canreal Injection. Pregnant or breastfeeding mothers should inform their doctor before receiving this medicine. Canreal Injection is not recommended for children as efficacy and safety have not been established. People affected with active pathological bleeding (peptic ulcer, intracranial or brain haemorrhage) and a history of stroke or transient ischemic attack (TIA) should not take Canreal Injection.

Drug-Drug Interactions

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CangrelorPonatinib
Severe

Drug-Drug Interactions

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How does the drug interact with Canreal Injection:
Co-administration of Canreal Injection with Mifepristone may increase the risk and/or severity of vaginal bleeding in women.

How to manage the interaction:
Although there is an interaction, Canreal Injection can be taken with Mifepristone if prescribed by the doctor. Consult the prescriber if you notice prolonged or heavy bleeding. Do not discontinue the medication without consulting a doctor.
CangrelorPonatinib
Severe
How does the drug interact with Canreal Injection:
Co-administration of Canreal Injection with Ponatinib may increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction, Canreal Injection can be taken with ponatinib if prescribed by the doctor. Consult the prescriber if you notice any unusual bleeding or bruising or other signs and symptoms of bleeding such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Canreal Injection:
Taking Canreal Injection with Fondaparinux can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Canreal Injection and Fondaparinux, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting. Do not stop using any medications without talking to a doctor.
How does the drug interact with Canreal Injection:
Co-administration of Canreal Injection with Warfarin may increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction, Canreal Injection can be taken with warfarin if prescribed by the doctor. Consult a prescriber if you notice any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not continue the medication without consulting a doctor.
How does the drug interact with Canreal Injection:
Co-administration of Canreal Injection with Heparin can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Although there is a possible interaction between Heparin and Canreal Injection, you can take these medicines together if prescribed by a doctor. However, if you have any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, you should seek immediate medical attention. Do not stop using any medications without a doctor's advice.
CangrelorDesirudin
Severe
How does the drug interact with Canreal Injection:
Co-administration of Desirudina and Canreal Injection may increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Canreal Injection and Desirudin, but it can be taken if prescribed by a doctor. If you notice any of these signs, it's important to contact your doctor right away: difficulty with bleeding, complications, bruising, feeling dizzy or lightheaded, dark or sticky stools, intense headache, weakness, or bleeding and vomiting. Do not stop using any medications without a doctor's advice.
How does the drug interact with Canreal Injection:
Co-administration of Tirofiban with Canreal Injection can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Tirofiban and Canreal Injection, you can take these medicines together if prescribed by your doctor. However, consult doctor immediately if you experience any unusual bleeding or bruising, or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness. Do not stop using any medications without a doctor's advice.
How does the drug interact with Canreal Injection:
Co-administration of Canreal Injection with Prasugrel and reduce its effectiveness if used at the same time.

How to manage the interaction:
Taking Canreal Injection may block the action of prasugrel and reduce its effectiveness if used at the same time. Therefore, prasugrel should be given after the Canreal Injection infusion is complete. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Canreal Injection:
Co-administration of Canreal Injection with Alteplase can increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Canreal Injection and Alteplase, but it can be taken if prescribed by a doctor. If you notice any of these signs, it's important to contact a doctor right away: difficulty with bleeding, complications, bruising, feeling dizzy or lightheaded, dark or sticky stools, intense headache, weakness, or bleeding or vomiting. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Canreal Injection:
Coadministration of Canreal Injection and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Canreal Injection and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a diet rich in whole grains, vegetables, fruits, skinless poultry, fish, eggs, and low-fat dairy products.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight with proper diet and exercise.
  • Managing stress with meditation, yoga, and massage.
  • Avoid eating fried food, fast food, boxed food, canned food, and processed frozen meals.

Habit Forming

No

Therapeutic Class

PLATELET AGGREGATION INHIBITOR

Drug-Diseases Interactions

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CANGRELOR-50MGHaemorrhage, not elsewhere classified
Severe

Drug-Diseases Interactions

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CANGRELOR-50MGHaemorrhage, not elsewhere classified
Severe
How does the disease interact with Canreal Injection:
Patients taking a TNF blocker alone or in combination with other immunosuppressive or myelosuppressive medications should have infections thoroughly watched for.

How to manage the interaction:
Canreal Injection is contraindicated in people with active bleeding.

FAQs

Canreal Injection works by inhibiting the clumping of platelets, thereby reducing the chance of blood clot formation. This helps in reducing the rate of cardiovascular events such as myocardial infarction (heart attack), repeat coronary revascularization, and stent thrombosis (ST).

Canreal Injection prevents the formation of blood clots, so it might increase the risk of bleeding during a percutaneous coronary intervention (PCI) procedure. Consult a doctor immediately if you notice excess bleeding.

Canreal Injection may cause anaemia (low haemoglobin and low red blood cell count). So it would be best if you include iron-rich food in your diet to prevent anaemia.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • IBUPROFEN
  • CELECOXIB
  • CLOPIDOGREL
  • ENOXAPARIN
  • TICAGRELOR
  • PRASUGREL
  • RIVAROXABAN

Special Advise

 

Disease/Condition Glossary

Blood clot: Platelets are small cell particles that circulate in the blood. When the blood vessel is damaged or cut, the platelets clump together and lead to the formation of a clot. Thus it prevents bleeding. The formation of clots in arteries can cut off the blood supply, leading to heart attack, stroke or death. Clot formation in the arteries that supply blood to the heart may cause reduced blood flow which could lead to unstable angina (chest pain).

Myocardial infarction: Myocardial infarction, also known as a heart attack or stroke, could occur due to the lack of blood and oxygen supply in the heart. Symptoms include chest pain, upper body pain, sweating, weakness, trouble breathing, lightheadedness and nausea.

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