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Written By Divya L , PharmaD
Reviewed By Veda Maddala , M Pharmacy
Non returnable*
COD available

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Composition :

FLUCONAZOLE-200MG

Manufacturer/Marketer :

Medimarck Biotech

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Canzol-IV 200 mg Injection 1 ml

Canzol-IV 200 mg Injection 1 ml belongs to the class of medicines called 'antifungals' used to treat a broad range of infections caused by fungi and yeast. A fungal infection is caused when a fungus invades and affects any part of the body, including the mouth, throat, oesophagus, lungs, bladder, genital area, and blood.

Canzol-IV 200 mg Injection 1 ml contains ‘Fluconazole’ that kills or prevents fungi or yeast growth by inhibiting an enzyme responsible for its normal fat metabolism. This interferes with the formation of the fungal cell membrane. As a result, fungal or yeast cells get killed or their growth is minimized.

Canzol-IV 200 mg Injection 1 ml may cause common side effects like headache, diarrhoea, nausea, stomach upset, dizziness, stomach pain, and altered food tastes. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Inform your doctor if you are allergic to any of the components in Canzol-IV 200 mg Injection 1 ml. Let your doctor know if you have any liver, kidney or heart problems before starting Canzol-IV 200 mg Injection 1 ml. Pregnant and breastfeeding women should consult their doctor before starting Canzol-IV 200 mg Injection 1 ml. It is advised to avoid alcohol intake while using Canzol-IV 200 mg Injection 1 ml to prevent any undesirable effects.

Uses of Canzol-IV 200 mg Injection 1 ml

Fungal infections.

Directions for Use

Canzol-IV 200 mg Injection 1 ml will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Canzol-IV 200 mg Injection 1 ml is used to treat various fungal or yeast infections, such as vaginal candidiasis, oropharyngeal candidiasis (thrush, oral thrush), oesophagal candidiasis (candida esophagitis), candida infections (urinary tract infections, peritonitis), and cryptococcal meningitis. Besides this, Canzol-IV 200 mg Injection 1 ml is also used to prevent candidiasis and coccidioidomycosis in patients who receive cancer or radiation treatment while undergoing bone marrow transplantation. Canzol-IV 200 mg Injection 1 ml is effective in treating soft tissue and pulmonary infections when compared to other azole antifungal drugs. It works by killing the fungus/yeast and preventing its growth by inhibiting the fungal cell membrane formation.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Canzol-IV 200 mg Injection 1 ml

  • Headache
  • Diarrhoea
  • Nausea
  • Stomach upset
  • Dizziness
  • Stomach pain
  • Altered food tastes

Drug Warnings

Please inform your doctor if you use any prescription, or non-prescription medicines, including vitamin and herbal supplements before using Canzol-IV 200 mg Injection 1 ml. Do not use Canzol-IV 200 mg Injection 1 ml if you are allergic to any of its components. Let your doctor know if you have any liver, kidney, or heart problems, a weakened immune system, diabetes, cancer, or low blood magnesium or potassium levels. Pregnant or lactating women should consult the doctor before taking Canzol-IV 200 mg Injection 1 ml. Do not drive or operate machinery if you experience dizziness or other side effects that may affect your mental ability to drive. Avoid alcohol consumption along with Canzol-IV 200 mg Injection 1 ml to avoid undesirable effects.

Drug-Drug Interactions

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FluconazoleEliglustat
Critical
FluconazoleLomitapide
Critical

Drug-Drug Interactions

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FluconazoleEliglustat
Critical
How does the drug interact with Canzol-IV 200 mg Injection 1 ml:
When Eliglustat and Canzol-IV 200 mg Injection 1 ml are taken together, Canzol-IV 200 mg Injection 1 ml can significantly increase the blood levels of eliglustat.

How to manage the interaction:
Taking Canzol-IV 200 mg Injection 1 ml with Eliglustat together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, slow heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without consulting a doctor.
FluconazoleLomitapide
Critical
How does the drug interact with Canzol-IV 200 mg Injection 1 ml:
When Lomitapide is taken with Canzol-IV 200 mg Injection 1 ml, may increase the blood levels of lomitapide.

How to manage the interaction:
Taking Canzol-IV 200 mg Injection 1 ml with Lomitapide together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
FluconazoleErythromycin
Critical
How does the drug interact with Canzol-IV 200 mg Injection 1 ml:
Taking Canzol-IV 200 mg Injection 1 ml with Erythromycin can increase the risk of heart rhythm problems.

How to manage the interaction:
Taking Canzol-IV 200 mg Injection 1 ml with Erythromycin together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
FluconazoleAstemizole
Critical
How does the drug interact with Canzol-IV 200 mg Injection 1 ml:
When Astemizole is taken with Canzol-IV 200 mg Injection 1 ml, the body's ability to break down Astemizole may be reduced.

How to manage the interaction:
Taking Canzol-IV 200 mg Injection 1 ml with Astemizole can lead to an interaction, please consult a doctor before taking it. Do not discontinue the medications without of consulting a doctor.
FluconazoleRanolazine
Severe
How does the drug interact with Canzol-IV 200 mg Injection 1 ml:
Co-administration of Ranozaline with Canzol-IV 200 mg Injection 1 ml may increase the blood levels and effects of Ranolazine.

How to manage the interaction:
Although there is a possible interaction, Canzol-IV 200 mg Injection 1 ml can be taken with Ranolazine if prescribed by the doctor. Consult the doctor if you experience sudden lightheadedness, dizziness, shortness of breath, fainting, or heart palpitations during treatment with these medications. Do not discontinue the medications without consulting a doctor.
FluconazoleVemurafenib
Severe
How does the drug interact with Canzol-IV 200 mg Injection 1 ml:
Taking Canzol-IV 200 mg Injection 1 ml with vemurafenib may increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction, Canzol-IV 200 mg Injection 1 ml can be taken with vemurafenib if prescribed by the doctor. Consult the doctor if you experience sudden lightheadedness, dizziness, shortness of breath, fainting, or heart palpitations during treatment with these medications. Do not discontinue the medications without a doctor's advice.
FluconazoleAcetohexamide
Severe
How does the drug interact with Canzol-IV 200 mg Injection 1 ml:
Co-administration of Canzol-IV 200 mg Injection 1 ml with Acetohexamide may increase the blood levels and effects of Acetohexamide and more likely to experience hypoglycemia (low blood glucose levels).

How to manage the interaction:
Although taking Canzol-IV 200 mg Injection 1 ml and Acetohexamide together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these symptoms - low blood sugar, headache, dizziness, feeling tired, feeling anxious, confusion, shaking, feeling sick, feeling hungry, weakness, or a fast heartbeat - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
FluconazoleTeriflunomide
Severe
How does the drug interact with Canzol-IV 200 mg Injection 1 ml:
Co-administration of Teriflunomide with Canzol-IV 200 mg Injection 1 ml may increase the risk of liver problems.

How to manage the interaction:
There may be a possibility of interaction between Canzol-IV 200 mg Injection 1 ml and Teriflunomide, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away: liver problems, fever, feeling cold, joint discomfort, swelling, bruising, skin irritation, itching, not feeling hungry, tiredness, feeling sick, throwing up, stomach ache, dark urine, liver harm, or bleeding. Do not stop using any medications without a doctor's advice.
FluconazoleAlfentanil
Severe
How does the drug interact with Canzol-IV 200 mg Injection 1 ml:
Co-administration of Alfentanil and Canzol-IV 200 mg Injection 1 ml may significantly increase the blood levels of ALfentanil which may increase the risk and/or severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Alfentanil and Canzol-IV 200 mg Injection 1 ml, you can take these medicines together if prescribed by a doctor. These symptoms include feeling very tired, having trouble breathing, feeling dizzy or lightheaded, having low blood pressure, having an irregular heartbeat, or having any other problems. Do not stop using any medications without a doctor's advice.
FluconazoleDicoumarol
Severe
How does the drug interact with Canzol-IV 200 mg Injection 1 ml:
Taking Canzol-IV 200 mg Injection 1 ml with Dicumarol may increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction, Canzol-IV 200 mg Injection 1 ml can be taken with Dicumarol if prescribed by the doctor. Consult the doctor if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue the medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Use mild soap while taking baths and prefer warm baths.
  • Avoid harsh products on your skin.
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Avoid or limit the intake of alcohol and caffeine.
  • Take non-starchy vegetables and gluten-free foods.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS

Canzol-IV 200 mg Injection 1 ml Substitute

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Author Details

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Drug-Diseases Interactions

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FLUCONAZOLE-200MGOther diseases of liver
Severe
FLUCONAZOLE-200MGOther cardiac arrhythmias
Moderate

Drug-Diseases Interactions

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FLUCONAZOLE-200MGOther diseases of liver
Severe
How does the disease interact with Canzol-IV 200 mg Injection 1 ml:
Hepatotoxicity has only sometimes been linked to the usage of Canzol-IV 200 mg Injection 1 ml. There have been cases of reversible idiosyncratic hepatitis, cholestasis, and deadly fulminant hepatic failure; the latter generally affects people with substantial underlying medical disorders who are also taking several concurrent drugs. Patients with pre-existing hepatic problems should have periodic liver function tests done, especially during prolonged medication. If liver enzyme levels continue to rise or worsen, treatment should be stopped.

How to manage the interaction:
In patients with preexisting liver abnormalities, particularly during prolonged therapy, liver function tests should be done regularly. Treatment should be withdrawn if persistent elevations or worsening of liver enzyme levels occur.
FLUCONAZOLE-200MGOther cardiac arrhythmias
Moderate
How does the disease interact with Canzol-IV 200 mg Injection 1 ml:
The QT interval on the ECG has been shown to be prolonged by some azole antifungals. During postmarketing experience, there have been a few isolated incidences of QT prolongation and torsade de pointes; these reports typically involved critically ill patients with a number of complicating risk factors, including structural cardiac disease, electrolyte problems, and concurrent medicines. Patients with illnesses that could cause proarrhythmic symptoms should take these medications cautiously. It is best to avoid using drugs that could potentially enhance the risk of cardiotoxicity concurrently.

How to manage the interaction:
It should be administered with caution to patients with heart problems. Concomitant use with other medications that have potential to increase the risk of cardiotoxicity should be avoided.
FLUCONAZOLE-200MGCare involving dialysis
Moderate
How does the disease interact with Canzol-IV 200 mg Injection 1 ml:
Hemodialysis effectively removes Canzol-IV 200 mg Injection 1 ml from the body. Following three hours of dialysis, it has been demonstrated that plasma levels of Canzol-IV 200 mg Injection 1 ml decrease by 50%. After hemodialysis, Canzol-IV 200 mg Injection 1 ml should be taken.

How to manage the interaction:
Canzol-IV 200 mg Injection 1 ml should be administered after hemodialysis.

FAQs

Canzol-IV 200 mg Injection 1 ml works by killing the fungus/yeast and preventing its growth by inhibiting the fungal cell membrane formation. Thus, it treats fungal infections.

Co-administration of terfenadine (anti-histamine), cisapride (antacid) with Canzol-IV 200 mg Injection 1 ml is not recommended. However, consult your doctor before taking Canzol-IV 200 mg Injection 1 ml with other medicines.

Canzol-IV 200 mg Injection 1 ml may not be suitable for some people who have a weakened immune system, diabetes, cancer, or low blood magnesium or potassium levels. However, seek a doctor's advice before using Canzol-IV 200 mg Injection 1 ml if you have a previous medical history.

Diarrhoea could be a side effect of Canzol-IV 200 mg Injection 1 ml. Drink plenty of fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if your condition does not improve or if it worsens.

Drug-Drug Interactions Checker List

  • TERFENADINE
  • ASTEMIZOLE
  • CISAPRIDE
  • PHENYTOIN
  • CYCLOSPORIN
  • TACROLIMUS
  • RIFAMPIN
  • THEOPHYLLINE
  • RIFABUTIN

Special Advise

  • Regular liver function tests are advised while on treatment with Canzol-IV 200 mg Injection 1 ml.
  • Inform your doctor immediately if you develop rashes or lesions while on treatment with Canzol-IV 200 mg Injection 1 ml.

Disease/Condition Glossary

Fungal infection: It occurs when a fungus enters, infects, and multiplies in the body. Fungi can live in water, soil, air, and plants. Fungi affect any part of the body, including the mouth, throat, oesophagus, lungs, bladder, genital area, and blood. Mild fungal skin infections are common and can cause rashes. Fungal infections affecting body organs like the lungs can cause flu or tuberculosis. Some fungal diseases like cryptococcal meningitis and blood infections can be fatal.

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