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  3. Cargrel-AV 10 Tablet 10's

Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Sunny S , MBBS
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Manufacturer/Marketer :

Olcare Laboratories Pvt Ltd

Consume Type :

Oral

Return Policy :

Not Returnable

About Cargrel-AV 10 Tablet 10's

Cargrel-AV 10 Tablet 10's is a combination drug composed of a blood-thinning agent and cholesterol-lowering agent primarily used to prevent heart attack and stroke in the future. It lowers the raised level of cholesterol and fats (triglycerides) in our bodies. A heart attack occurs when your coronary arteries (blood vessels supplying blood and oxygen to the heart) becomes blocked due to the build-up of fats (plaque), including cholesterol. These plaques narrow the arteries, leading to atherosclerosis and coronary artery disease, mainly for most heart attacks.

Cargrel-AV 10 Tablet 10's is composed of two medicines, namely: Atorvastatin and Clopidogrel. Atorvastatin is a lipid-lowering medication which blocks the enzyme required to make cholesterol in the body. As a result, it lowers the bad cholesterol (low-density lipoproteins or LDL) and triglycerides (TG) and increases the levels of good cholesterol (high-density lipoproteins or HDL). Clopidogrel is a blood thinner (anticoagulant) that collectively prevents a clot in the blood vessels. Together Cargrel-AV 10 Tablet 10's reduces the increased levels of bad cholesterol (low-density lipoprotein and triglycerides) and prevents blood clots, thereby reducing the risk of heart attack, stroke and heart-related chest pain (angina).

You can take Cargrel-AV 10 Tablet 10's with food or without food. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. Your doctor will advise you on how often you take this medicine based on your medical condition. You may sometimes experience headaches, ankle swelling (oedema), slow heart rate, and nausea. Cargrel-AV 10 Tablet 10's is known to cause dizziness, so driving should be avoided. Most of these side effects of Cargrel-AV 10 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking a Cargrel-AV 10 Tablet 10's of your own. Suddenly stopping using Cargrel-AV 10 Tablet 10's may worsen your condition and increase your risk of a future heart attack. Let your doctor know if you are sensitive to atorvastatin or clopidogrel or have any active liver disease (liver enzyme abnormalities), active bleeding issues (like peptic ulcer, brain haemorrhage), or muscle problem (myopathy, rhabdomyolysis). The patient should inform the doctor they are taking Cargrel-AV 10 Tablet 10's before any surgery or any new medicine is taken. Atorvastatin, present in Cargrel-AV 10 Tablet 10's is a pregnancy category X drug, so it should not be given to pregnant women. It may cause harm to the foetus if administered to pregnant or breastfeeding women.

Uses of Cargrel-AV 10 Tablet 10's

Hyperlipidemia (Increased cholesterol), Prevention of heart attack, Prevention of stroke.

Directions for Use

Swallow the tablet as a whole with water; do not crush, break or chew it.

Key Benefits

Atorvastatin is a lipid-lowering medication that blocks the enzyme required to make cholesterol in the body. As a result, it lowers the bad cholesterol (low-density lipoproteins or LDL) and triglycerides (TG) and increases the levels of good cholesterol (high-density lipoproteins or HDL). Clopidogrel is a blood thinner (anticoagulant) that collectively prevents clot formation in the blood vessels. Together Cargrel-AV 10 Tablet 10's reduces the increased levels of bad cholesterol (low-density lipoprotein and triglycerides) and prevents blood clots, thereby reducing the risk of heart attack, stroke and heart-related chest pain (angina).

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Tell your doctor if you are sensitive to Atorvastatin or clopidogrel, have any active liver disease, active bleeding issues (like peptic ulcer, brain haemorrhage), are pregnant or planning to become pregnant or breastfeeding. The patient should inform the doctor that they are taking Cargrel-AV 10 Tablet 10's before any surgery is scheduled or any new medicine is taken. Atorvastatin present in Cargrel-AV 10 Tablet 10's is a pregnancy category X drug, so it is contraindicated in pregnant women. As it may cause harm to the foetus if administered to pregnant women. The risk of muscle disease might increase if Cargrel-AV 10 Tablet 10's is taken with an antibiotic (clarithromycin), anti-HIV drugs (ritonavir, lopinavir, darunavir, atazanavir, indinavir) and antifungal (itraconazole). Coadministration with anticoagulants like warfarin may cause gastric bleeding and other bleeding problems. So, if you are using any blood-thinning agents, let your doctor know about this. Cargrel-AV 10 Tablet 10's contains Atorvastatin which can cause muscle problems like myopathy and rhabdomyolysis. Patients with active liver disease should use the Cargrel-AV 10 Tablet 10's with caution. The safety and effectiveness of Cargrel-AV 10 Tablet 10's have not been established, so its use should be avoided in paediatric patients or children younger than ten years of age. Discontinuation of Cargrel-AV 10 Tablet 10's may lead to cardiovascular events like heart attack, stroke and angina (heart-related chest pain). Hence, you should consult a doctor before stopping the dose of Cargrel-AV 10 Tablet 10's.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Cargrel-AV 10 Tablet:
Taking Cargrel-AV 10 Tablet with Posaconazole can increase the blood levels of Cargrel-AV 10 Tablet. This can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between posaconazole with Cargrel-AV 10 Tablet, they can be taken together if advised by your doctor. However, contact the doctor if you experience unexplained muscle pain, weakness, fever, chills, joint pain or swelling, unusual bleeding, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark coloured urine, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cargrel-AV 10 Tablet:
Taking Cargrel-AV 10 Tablet together with mifepristone increases the risk of vaginal bleeding in women.

How to manage the interaction:
Although taking Cargrel-AV 10 Tablet with mifepristone is not recommended, that would certainly result in interaction, it can be taken if a doctor prescribes it. If you experience prolonged and heavy bleeding, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Cargrel-AV 10 Tablet:
When Selexipag and Cargrel-AV 10 Tablet are taken together, the body's ability to break down Selexipag may be reduced.

How to manage the interaction:
Taking Cargrel-AV 10 Tablet with Selexipag is not recommended, please consult your doctor before taking it. They can be taken if prescribed by your doctor.
How does the drug interact with Cargrel-AV 10 Tablet:
Coadministration of Nicotinamide with Cargrel-AV 10 Tablet can increase the risk and severity of side effects like rhabdomyolysis (breakdown of skeletal muscle) or kidney damage.

How to manage the interaction:
Taking Nicotinamide with Cargrel-AV 10 Tablet together is used with caution as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unexplained muscle pain, muscle stiffness or tenderness, fever, dark-colored urine, or weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
AtorvastatinTelithromycin
Severe
How does the drug interact with Cargrel-AV 10 Tablet:
Using Cargrel-AV 10 Tablet together with telithromycin may significantly increase the blood levels of Cargrel-AV 10 Tablet.

How to manage the interaction:
Taking Telithromycin with Cargrel-AV 10 Tablet together can result in an interaction, but it can be taken if a doctor has advised it. You should seek immediate medical attention if you develop fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes. Do not stop using any medications without talking to a doctor.
AtorvastatinNefazodone
Severe
How does the drug interact with Cargrel-AV 10 Tablet:
Using Cargrel-AV 10 Tablet together with nefazodone may significantly increase the blood levels of Cargrel-AV 10 Tablet.

How to manage the interaction:
Taking Cargrel-AV 10 Tablet with Nefazodone together can result in an interaction, but it can be taken if a doctor has advised it. You should seek immediate medical attention if you develop fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.
How does the drug interact with Cargrel-AV 10 Tablet:
Taking Cargrel-AV 10 Tablet with indinavir may considerably raise Cargrel-AV 10 Tablet levels in the blood.

How to manage the interaction:
Taking Cargrel-AV 10 Tablet and indinavir together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
AtorvastatinTroleandomycin
Severe
How does the drug interact with Cargrel-AV 10 Tablet:
Using Cargrel-AV 10 Tablet together with troleandomycin may significantly increase the blood levels of Cargrel-AV 10 Tablet.

How to manage the interaction:
Taking Cargrel-AV 10 Tablet with Troleandomycin together can result in an interaction, but it can be taken if a doctor has advised it. You should seek immediate medical attention if you develop fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.
How does the drug interact with Cargrel-AV 10 Tablet:
Coadministration of Erlotinib with Cargrel-AV 10 Tablet can raise the chance of side effects (liver injury and rhabdomyolysis, an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury).

How to manage the interaction:
Taking Erlotinib with Cargrel-AV 10 Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unexplained muscle pain, muscle stiffness or tenderness, fever, dark-colored urine, or weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Cargrel-AV 10 Tablet:
Using Cargrel-AV 10 Tablet together with itraconazole may significantly increase the blood levels of Cargrel-AV 10 Tablet.

How to manage the interaction:
Coadministration of Cargrel-AV 10 Tablet along with itraconazole together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark-colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Low cholesterol diet along with a regular exercise regime is found to complement treatment with Cargrel-AV 10 Tablet 10's effectively.
  • Stick to a freshly prepared home-cooked meal and avoid processed, packed foods that contain hidden sugar and extra calories.
  • Try to replace most of your saturated fats with unsaturated fats to reduce total cholesterol and LDL cholesterol (bad cholesterol) quickly.
  • Foods like avocados, olive oil, fatty fish and nuts contain many heart-healthy unsaturated fats, so eating them regularly is beneficial.
  • Include a diet enriched in fats like fish oils, polyunsaturated oils, and omega-3 fatty acids, which are good for heart health.
  • Quit smoking and avoid excessive intake of alcohol.

Side Effects of Cargrel-AV 10 Tablet 10's

  • Bleeding (stomach, gastrointestinal, nose bleeding)
  • Rash
  • Diarrhoea
  • Stomach ulcer
  • Muscle disease (like myopathy, rhabdomyolysis)
  • Abdominal pain

Habit Forming

No

Therapeutic Class

[CARDIOVASCULAR AGENTS]

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Yes, Cargrel-AV 10 Tablet 10's contains clopidogrel which prevents blood clotting. It works by preventing platelets (a type of blood cell) from sticking together and forming clots which in turn prevents the risk of heart attack and stroke.

Yes, taking Cargrel-AV 10 Tablet 10's can increase the risk of bleeding as it contains aspirin and clopidogrel which belongs to a class of blood-thinning agents. So, please be very cautious while shaving, cutting fingernails or toenails, or using sharp objects to avoid any bleeding. Let your doctor know before going any surgical procedure, that you are taking Cargrel-AV 10 Tablet 10's.

No. Cargrel-AV 10 Tablet 10's contains Atorvastatin which is pregnancy category X medicine and can cause harm to both pregnant mother and unborn baby. Even if you are planning for pregnancy tell your doctor that you are using Cargrel-AV 10 Tablet 10's.

Yes, prolonged use of Cargrel-AV 10 Tablet 10's may cause muscle diseases like myopathy and rhabdomyolysis. So if you feel any musculoskeletal pain after taking Cargrel-AV 10 Tablet 10's consult your doctor about this issue.

Do not drink grapefruit juice while taking Cargrel-AV 10 Tablet 10's. Grapefruit juice may increase the blood-thinning effect of your medicine.

Drinking alcohol with Cargrel-AV 10 Tablet 10's may damage your liver and increase liver enzymes like transaminase. So, Cargrel-AV 10 Tablet 10's should be used with caution who consume alcohol and/or have past history of liver disease.

If you accidentally take an overdose of Cargrel-AV 10 Tablet 10's you may have liver problems (increased secretion of liver enzymes) and bleeding complications. If problems persist you should immediately go to the nearby clinic or hospital.

You should have a total lipid profile (TG, HDL, LDL, VLDL, TC) and Blood coagulation tests like Complete blood count (CBC), Factor V assay, Fibrinogen Test, Prothrombin time (PT or PT-INR), Platelet count, Thrombin time and Bleeding time to analyze your blood clot timing and cholesterol level.

Drug-Drug Interactions Checker List

  • CLARITHROMYCIN
  • RITONAVIR
  • LOPINAVIR
  • DARUNAVIR
  • ATAZANAVIR
  • INDINAVIR
  • ITRACONAZOLE
  • WARFARIN
  • COUMADIN
  • HEPARIN
  • COLCHICINE
  • DIGOXIN
  • CYCLOSPORINE

Special Advise

  • If you have a high cholesterol level, try to have a lipid profile test (LFT) every 6 months.

 

Disease/Condition Glossary

Atherosclerosis: Atherosclerosis occurs when fats, cholesterol, and other substances known as plaque deposit on your artery walls that restrict blood flow. This plaque formation triggers blood clots, narrows the arteries' size, and hardens them. This, in turn, can lead to various heart complications like atherosclerosis, heart attack, heart-related chest pain (angina), and stroke. However, it can also affect the body's arteries apart from the heart.

Have a query?

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Alcohol

Safe if prescribed

Cargrel-AV 10 Tablet 10's should not be taken with alcohol as it may worsen your liver condition with increased secretion of liver enzymes like transaminase. Keep your doctor informed if you drink alcohol.

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Pregnancy

Consult your doctor

Cargrel-AV 10 Tablet 10's contains Atorvastatin which is a pregnancy category X medicine. It may cause harm to both the pregnant mother and the fetus. Hence, it is not recommended for pregnant women and those who are planning for a pregnancy. Your doctor might prescribe you only in an extreme case.

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Breast Feeding

Consult your doctor

Take Cargrel-AV 10 Tablet 10's only when prescribed, it is known to pass on in a limited quantity via breast milk to the child.

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Driving

Safe if prescribed

Drive with caution, Cargrel-AV 10 Tablet 10's usually causes blurry vision and may affect driving ability.

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Liver

Consult your doctor

Cargrel-AV 10 Tablet 10's to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Consult your doctor

Cargrel-AV 10 Tablet 10's to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

Cargrel-AV 10 Tablet 10's is not recommended for children below the age of 10 years. The safety and effectiveness of Cargrel-AV 10 Tablet 10's have not been established in children due to limited testing of Cargrel-AV 10 Tablet 10's on children by competent authorities worldwide.

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