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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
COD available

Online payment accepted

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Composition :

CEFDINIR-300MG

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

Cefrine 300 mg Capsule belongs to a class of medication called 'antibiotics' used to treat several bacterial infections of the urinary tract, bones and joints, heart, lungs, brain, chest, ears, skin or soft tissues. The bacterial infection is a condition in which harmful bacteria grows in the body and cause infection. It can infect any part of the body and multiple very quickly. Cefrine 300 mg Capsule does not work against infections caused by a virus such as flu or a common cold. 

Cefrine 300 mg Capsule contains 'Cefdinir' a cephalosporin antibiotic that works by interfering with the formation of the bacterial cell wall (a protective covering) necessary for their survival. Thereby damages the bacterial cell wall and kills bacteria.

Take Cefrine 300 mg Capsule as prescribed by your doctor. You are advised to take Cefrine 300 mg Capsule for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience diarrhoea, nausea, stomach pain, vomiting, rash, headache or vaginal itching or discharge. Most of these side effects of Cefrine 300 mg Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Cefrine 300 mg Capsule , cephalosporin antibiotics or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, inform your doctor before taking Cefrine 300 mg Capsule . Cefrine 300 mg Capsule is not recommended for babies below 6 months of age as the safety and effectiveness were not established. Drive only if you are alert as Cefrine 300 mg Capsule may cause dizziness. You are advised to maintain a time gap of a minimum of 2 hours between taking Cefrine 300 mg Capsule and antacids containing aluminium, magnesium, iron supplements and multivitamins containing iron. These may reduce the absorption of Cefrine 300 mg Capsule by the body.

Bacterial infections
Tablet/Capsule: Swallow it as a whole with a glass of water. Do not crush, chew or break it. Syrup: Take it by mouth using the measuring cup provided with the pack. Shake the bottle well before each use.

Cefrine 300 mg Capsule contains Cefdinir a cephalosporin antibiotic used in the treatment of several bacterial infections. Cefdinir is a broad-spectrum antibiotic that acts against both aerobic (grow in the presence of oxygen) and anaerobic (grow in the absence of oxygen) gram-negative and gram-positive bacteria. It interferes with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Thereby damages the bacterial cell wall and kills bacteria. 

Store in a cool and dry place away from sunlight

Side Effects of Cefrine 300 mg Capsule

  • Diarrhoea
  • Nausea
  • Stomach pain
  • Vomiting
  • Rash
  • Headache
  • Vaginal itching or discharge

If you are allergic to Cefrine 300 mg Capsule , cephalosporin antibiotics or any other medicines, please tell your doctor. If you have kidney problems or inflammation of the large intestine, inform your doctor before taking Cefrine 300 mg Capsule . If you are pregnant or breastfeeding, consult a doctor before taking Cefrine 300 mg Capsule . Cefrine 300 mg Capsule is not recommended for babies below 6 months of age as the safety and effectiveness were not established. Drive only if you are alert as Cefrine 300 mg Capsule may cause dizziness. You are recommended to complete the full course of Cefrine 300 mg Capsule as prescribed by your doctor for effective results. Cefrine 300 mg Capsule may interact with specific tests such as glucose (sugar) in urine and coomb’s test, giving false-positive results. Therefore, inform your doctor that you are taking Cefrine 300 mg Capsule before undergoing any tests. You are advised to maintain a time gap of a minimum of 2 hours between taking Cefrine 300 mg Capsule and antacids containing aluminium, magnesium, iron supplements and multivitamins containing iron. These may reduce the absorption of Cefrine 300 mg Capsule by the body. 

Drug-Drug Interactions

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CefdinirBCG vaccine
Critical
CefdinirFondaparinux
Severe

Drug-Drug Interactions

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CefdinirBCG vaccine
Critical
How does the drug interact with Cefrine 300 mg Capsule:
Taking Cefrine 300 mg Capsule with BCG vaccine may reduce the effects of BCG vaccine.

How to manage the interaction:
Taking Cefrine 300 mg Capsule with BCG vaccine is not recommended, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
CefdinirFondaparinux
Severe
How does the drug interact with Cefrine 300 mg Capsule:
Taking fondaparinux and Cefrine 300 mg Capsule may increase the effects of fondaparinux.

How to manage the interaction:
Although taking Cefrine 300 mg Capsule and Fondaparinux can evidently cause an interaction, it can be taken if your doctor has suggested it. In case you experience aby unusual effects like lightheadedness, dizziness, unusual bruising, bleeding tendencies, blood in stools or urine, consult a doctor. Do not stop using any medications without a doctor's advice.
CefdinirArgatroban
Severe
How does the drug interact with Cefrine 300 mg Capsule:
Taking Cefrine 300 mg Capsule with argatroban may lead to increase in the effects of Argatroban.

How to manage the interaction:
Although taking Cefrine 300 mg Capsule and Argatroban together can evidently cause an interaction, but it can be taken if prescribed by a doctor. In case you experience any side effects like chest tightness, shortness of breath, swelling of legs, or palpitations, consult a doctor. Do not stop using any medications without first talking to your doctor.
CefdinirDalteparin
Severe
How does the drug interact with Cefrine 300 mg Capsule:
Taking Cefrine 300 mg Capsule with dalteparin together may decrease the therapeutic effects of dalteparin.

How to manage the interaction:
Although taking Cefrine 300 mg Capsule and dalteparin can evidently cause an interaction, it can be taken if your doctor has suggested it. In case you experience aby unusual effects like lightheadedness, dizziness, unusual bruising, bleeding tendencies, blood in stools or urine, consult a doctor. Do not stop using any medications without a doctor's advice.
CefdinirBivalirudin
Severe
How does the drug interact with Cefrine 300 mg Capsule:
Taking Cefrine 300 mg Capsule with bivalirudin may increase the effects of bivalirudin.

How to manage the interaction:
Although taking Cefrine 300 mg Capsule and Argatroban together can evidently cause an interaction, but it can be taken if prescribed by a doctor. In case you experience any side effects like chest tightness, shortness of breath, swelling of legs, or palpitations, consult a doctor. Do not stop using any medications without first talking to your doctor.
CefdinirHeparin
Severe
How does the drug interact with Cefrine 300 mg Capsule:
Taking Cefrine 300 mg Capsule with heparin may enhance the effects of heparin by anticoagulation(preventing blood from clotting).

How to manage the interaction:
Although taking Cefrine 300 mg Capsule and Heparin can cause an interaction, it can be taken if a doctor has suggested it. In case you experience aby unusual effects like lightheadedness, dizziness, unusual bruising, bleeding tendencies, blood in stools or urine, consult a doctor. Do not stop using any medications without a doctor's advice.
CefdinirLepirudin
Severe
How does the drug interact with Cefrine 300 mg Capsule:
Taking Cefrine 300 mg Capsule with lepirudin may reduce the beneficial effects of therapy.

How to manage the interaction:
Although taking Cefrine 300 mg Capsule and Lepirudin together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without first talking to your doctor.
CefdinirCholera, live attenuated
Severe
How does the drug interact with Cefrine 300 mg Capsule:
Taking Cefrine 300 mg Capsule with Cholera vaccine can reduce the activity of the Cholera vaccine.

How to manage the interaction:
Taking Cefrine 300 mg Capsule with Cholera, live attenuated together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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CEFDINIR-300MGVitamin B complex foods, Vitamin B12 rich foods
Moderate

Drug-Food Interactions

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CEFDINIR-300MGVitamin B complex foods, Vitamin B12 rich foods
Moderate
Common Foods to Avoid:
Avocado, Beetroot, Cereals, Cheese, Chicken, Black Beans, Eggs, Clams, Chickpea, Whole Grains, Shellfish, Spinach, Salmon, Red Meat, Oysters, Potatoes, Kidney Beans, Mackerel, Milk, Kale, Tuna, Yogurt, Liver, Low-Fat Milk, Trout, Fortified Breakfast Cereal, Fish, Beef

How to manage the interaction:
Cefrine 300 mg Capsule and multivitamin with minerals should not be taken orally at the same time. Iron-containing products decreases the effects of Cefrine 300 mg Capsule. Although there is an interaction between Cefrine 300 mg Capsule and multivitamins, it can be taken if advised by a doctor. It should be taken two hours either before or after the dosage of the multivitamin with minerals.
  • Take probiotics after completing the full course of Cefrine 300 mg Capsule to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhea.
  • Certain fermented foods like cheese, yogurt, kombucha, sauerkraut, and kimchi can help to restore the good bacteria of the intestine.
  • Include fiber-rich foods, as they can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fiber-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains such as brown rice and whole-grain bread should be included in your diet.
  • Make sure you drink plenty of water or other fluids every day while you are taking Cefrine 300 mg Capsule .
  • Avoid alcohol consumption as it may increase adverse effects.
No
ANTIBIOTICS

Cefrine 300 mg Capsule Substitute

Substitutes safety advice
  • Sefdin 300 mg Capsule 10's

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    53.82per tablet
  • Avonir-300 Capsule 10's

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    42.30per tablet
  • ALDINIR 300MG CAPSULE

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    4.43per tablet
  • Cefdiel 300 mg Capsule 10's

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    34.96per tablet
  • Cefrine Capsule 4's

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    32.98per tablet

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Cefrine 300 mg Capsule contains Cefdinir, an antibiotic that works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Thereby damages the bacterial cell wall and kills bacteria.

You are not recommended to take Cefrine 300 mg Capsule with probenecid (used to lower high uric acid levels) as it may increase the levels of Cefrine 300 mg Capsule in blood and increase the risk of adverse effects such as diarrhoea, kidney problems, vomiting and nausea. However, please consult your doctor before taking Cefrine 300 mg Capsule with other medicines.

Cefrine 300 mg Capsule may cause diarrhoea as a common side effect. However, if the condition persists, worsens or if you notice blood or mucus in stools, avoid taking Cefrine 300 mg Capsule and consult a doctor immediately.

Cefrine 300 mg Capsule may interfere with urine test (for sugar) and Coomb’s test (blood test) giving false-positive results. Therefore, if you are about to undergo any laboratory tests, inform your doctor or lab technician that you are taking Cefrine 300 mg Capsule .

Cefrine 300 mg Capsule is not used to treat viral infections. Cefrine 300 mg Capsule is an antibiotic which is used to treat only bacterial infections.

You are advised to maintain a time gap of minimum 2 hours between taking Cefrine 300 mg Capsule and antacids containing aluminium and magnesium as they may reduce the absorption of Cefrine 300 mg Capsule by the body. However, please consult a doctor before taking other medicines with Cefrine 300 mg Capsule .

Drug-Drug Interactions Checker List

  • PROBENECID

If you are about to undergo any blood or urine tests, inform your doctor that you are taking Cefrine 300 mg Capsule as it may interfere with urine test (for sugar) and Coomb’s test (blood test).

Bacterial infection: It is a condition in which harmful bacteria grows in the body and cause infection. It can target any part of the body and multiply very quickly. Bacteria come in three basic shapes, namely spherical, rod or spiral-shaped. Bacteria may be gram-positive (have thick cell wall) or gram-negative (do not have cell wall). Appropriate tests are done to identify bacterial strains, and based on the results, proper medication is prescribed. Some common symptoms of bacterial infection include cough, fever and tiredness. 

Side effects of Cefrine 300 mg Capsule
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Your doctor may adjust the dose of your medication, discontinue, or switch to alternative medicines to manage your symptoms.
  • Drink plenty of water and caffeine-free drinks.
  • Eat more fibre by consuming fruits, vegetables, and whole grains.
  • Avoid processed, spicy, or fatty foods.
  • Try not to skip meals, delay eating, or eat too quickly.
  • Regular exercise can help improve digestion and promote better stool movement.
Managing Medication-Triggered Moniliasis (a yeast infection): A Step-by-Step Guide:
  • If you experience symptoms like itching, burning, redness, or discharge after taking medication, consult your doctor immediately and share your symptoms, medication regimen, and medical history.
  • Your doctor will assess your medication regimen to determine if it's contributing to the moniliasis and identify the best course of action to manage your condition.
  • Your doctor may prescribe antifungal medications or recommend other treatments to help clear up the infection. They may also suggest self-care measures to help manage symptoms and prevent future infections.
  • If your condition doesn't improve or persists, consult your doctor and report it. Your doctor will assess your progress, adjust your treatment plan, and provide advice to ensure the best outcome.
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