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  3. CELKERAN 5MG TABLET

CELKERAN 5MG TABLET, Pack of 1 TABLET
CELKERAN 5MG TABLET, Pack of 1 TABLET
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
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Whats That

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Composition :

CHLORAMBUCIL-5MG

Manufacturer/Marketer :

Levin Life Sciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About CELKERAN 5MG TABLET

CELKERAN 5MG TABLET belongs to a class of cytotoxic drugs, also known as chemotherapeutic agents, primarily used to treat various cancer conditions such as Hodgkin's disease, certain forms of non-Hodgkin's lymphoma, Chronic lymphocytic leukaemia, Waldenstrom's macroglobulinaemia, advanced Ovarian adenocarcinoma and Breast cancer. Cancer is a genetic change in which the body's cells divide uncontrollably and spread into surrounding tissues.

CELKERAN 5MG TABLET contains Chlorambucil, which works by slowing or stopping the growth of cancer cells in the body. Thus, it treats cancer efficiently.

Use CELKERAN 5MG TABLET as directed by your doctor. It may cause side effects, such as a drop in the number of blood cells and platelets, feeling sick (nausea), being sick (vomiting), sores in the mouth and throat, tiredness and missed menstrual periods (in girls and women). Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if any of these side effects persist or worsen.

Tell your doctor before prescribing CELKERAN 5MG TABLET if you have a history of bleeding disorders, heart or liver problems, radiation treatment, or any infection. Many other medications can interact with or be impacted by CELKERAN 5MG TABLET, so let your doctor know all your medications. This medicine has been shown to reduce the number of blood cells, making you more susceptible to infections. During treatment with this medication, you will need to have regular blood tests to assess your blood cells, as well as your kidney, liver, and heart function.

Do not take CELKERAN 5MG TABLET if you are allergic (hypersensitive) to Chlorambucil or any of the other ingredients of this medicine. Chlorambucil may increase the risk of developing other cancers. CELKERAN 5MG TABLET can disrupt a woman's natural menstrual cycle (period) and stop sperm production in men. It may induce permanent infertility (difficulty becoming pregnant); If you are pregnant, inform your doctor before starting this medication. It is not recommended for use in the first trimester of pregnancy. Effective birth control measures are advised for men and women while on treatment with this medicine. Call your doctor right away if you become pregnant while taking Chlorambucil. 

Uses of CELKERAN 5MG TABLET

Cancer

Directions for Use

Swallow the medicine as a whole with a glass of water. Do not break, crush or chew the tablet.

Medicinal Benefits

CELKERAN 5MG TABLET is a cytotoxic medicine, also known as a chemotherapeutic agent, primarily used to treat various cancer conditions such as Hodgkin's disease, certain forms of non-Hodgkin's lymphoma, Chronic lymphocytic leukaemia, Waldenstrom's macroglobulinaemia, Advanced ovarian adenocarcinoma and breast cancer. Chlorambucil, present in CELKERAN 5MG TABLET, works by slowing or stopping the growth of cancer cells in your body. Thus, it treats cancer efficiently.

Storage

Store in a cool and dry place away from sunlight
Side effects of Celkeran 5mg Tablet
  • Aim for at least five servings of a well-balanced diet per day that is full of vibrant fruits and vegetables.
  • Eat more whole foods, lean meats, and plant-based foods, and eat healthy fruits like bananas, oranges, and berries.
  • Limit alcohol intake and abstain from smoking to promote general wellbeing.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.

Drug Warnings

Before taking CELKERAN 5MG TABLET, inform your doctor about your medical history and ongoing therapies to rule out potential adverse effects or interactions. Always take CELKERAN 5MG TABLET as prescribed by your doctor. It's crucial to take your medication as directed. The dosage of this medicine is based on your condition. Your doctor may adjust your dose during therapy based on the treatment results. The drug chlorambucil can reduce the number of blood cells in your bone marrow. Your doctor will request laboratory testing before, during, and after therapy to determine whether this drug affects your blood cells. Keep all lab appointments. Before taking CELKERAN 5MG TABLET, inform your doctor if you are pregnant or breastfeeding. If you become pregnant while on treatment with Chlorambucil, tell your doctor.

Drug-Drug Interactions

verifiedApollotooltip
ChlorambucilBaricitinib
Severe
ChlorambucilCladribine
Severe

Drug-Drug Interactions

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ChlorambucilBaricitinib
Severe
How does the drug interact with Celkeran 5mg Tablet:
Coadministration of baricitinib and Celkeran 5mg Tablet can raise the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Celkeran 5mg Tablet if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscular aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.
ChlorambucilCladribine
Severe
How does the drug interact with Celkeran 5mg Tablet:
The combined Cladribine with Celkeran 5mg Tablet can increase the risk of developing serious infections.

How to manage the interaction:
Taking Cladribine with Celkeran 5mg Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
ChlorambucilTofacitinib
Severe
How does the drug interact with Celkeran 5mg Tablet:
Taking Tofacitinib with Celkeran 5mg Tablet may increase the risk of serious infection.

How to manage the interaction:
There may be a possibility of interaction between Tofacitinib and Celkeran 5mg Tablet, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blo, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
ChlorambucilThalidomide
Severe
How does the drug interact with Celkeran 5mg Tablet:
Taking thalidomide together with Celkeran 5mg Tablet may increase the risk of blood clots.

How to manage the interaction:
Although taking thalidomide and Celkeran 5mg Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
ChlorambucilEtanercept
Severe
How does the drug interact with Celkeran 5mg Tablet:
When Etanercept is used with Celkeran 5mg Tablet, the likelihood or severity of infection may increase.

How to manage the interaction:
Although taking Etanercept and Celkeran 5mg Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • After your treatment begins, several dietary adjustments can help you control side effects.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • Plant-based proteins are among the greatest meals to take during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans and legumes.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast and fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

CELKERAN 5MG TABLET Substitute

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:49 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

CELKERAN 5MG TABLET contains Chlorambucil, which works by slowing or stopping the growth of cancer cells in your body. Thus, it treats cancer efficiently.

Attend all your doctor's appointments while taking CELKERAN 5MG TABLET to ensure the therapy is effective. Regular blood tests and weight checks must be performed. While taking the CELKERAN 5MG TABLET, both men and women should use an effective means of contraception. Do not use any other medications unless prescribed by the doctor.

Do not stop taking CELKERAN 5MG TABLET on your own. Take CELKERAN 5MG TABLET for as long as your doctor prescribes it, depending on your medical condition. Do not hesitate to speak with your doctor if you experience difficulty taking CELKERAN 5MG TABLET.

Chlorambucil can cause a significant decrease in the number of blood cells and platelets. Your doctor may suggest laboratory tests before and during the treatment.

Chlorambucil may increase the risk that you will develop other cancers. Talk to your doctor about this risk.

Some dietary changes can help you manage side effects; for example, in case of diarrhoea-Choose foods or drinks with sodium (sports drinks or broth) and potassium (bananas and all-natural fruit juices).

Drug-Drug Interactions Checker List

  • BCG VACCINE
  • MUMPS (LIVE ATTENUATED)
  • INFLUENZA VIRUS VACCINE
  • ADALIMUMAB
  • CLOZAPINE
  • DEUCRAVACITINIB
  • CLADRIBINE
  • ETANERCEPT
  • FINGOLIMOD
  • LEFLUNOMIDE

Special Advise

  • When you take CELKERAN 5MG TABLET, your doctor will suggest regular blood tests to monitor the count of blood cells.

Disease/Condition Glossary

Cancer: Cancer is a genetic change in which the body's cells divide uncontrollably and spread into surrounding tissues. There are two types of cancer: benign (localized) and metastatic (spread to the whole body). Types of cancer include blood, lung, breast, etc. Cancer growth can be prevented by chemotherapy, radiation, and stem cell therapy.

Hodgkin's disease: Hodgkin lymphoma, commonly known as Hodgkin's disease, is a kind of cancer that affects the lymphatic system. Your lymphatic system is a component of your immune system. It aids in the defence of your body against infection and sickness. The lymph system comprises tissues and organs that generate, store, and transport white blood cells.

Chronic lymphocytic leukaemia: The most prevalent type of leukaemia in adults is chronic lymphocytic leukaemia (CLL). It is a form of cancer that begins in the bone marrow in cells that develop into specific white blood cells (called lymphocytes). Cancer (leukaemia) cells begin in the bone marrow and subsequently spread to the blood.

Waldenström macroglobulinemia: Waldenström macroglobulinemia is a rare bone marrow malignancy characterized by an excess of aberrant white blood cells. These aberrant cells resemble both B cells, which are white blood cells (lymphocytes), and plasma cells, which are more mature cells generated from B cells.

Ovarian cancer: Ovarian cancer begins in the ovaries (one of a pair of female reproductive glands in which the ova, or eggs, are formed). Advanced ovarian cancer indicates that the cancer has progressed beyond the ovary. It could have spread within the pelvis or abdomen or gone to other parts of the body, such as the lungs.

Breast Cancer: Breast cancer is a type of cancer that develops in breast cells. Breast cancer may form in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), the fatty tissue or the fibrous connective tissue within the breast. The tumour cells invade other healthy breast cells and can travel to lymph nodes, a primary pathway for the cancer cells to move to other body parts.

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