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Written By Veda Maddala , M Pharmacy
Reviewed By Sureshvarma D , MPharma
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer :

Calren Care Lifesciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Celvir 450Mg Tablet

Celvir 450Mg Tablet belongs to a class of drugs called antivirals used to treat cytomegalovirus (CMV) infection of the retina of the eye in adult AIDS patients. Also, Celvir 450Mg Tablet is used to prevent CMV infection in patients who received an organ transplant from a donor infected with CMV. Cytomegalovirus (CMV) retinitis is a viral infection of the retina (light-sensing cells) caused by cytomegalovirus.

Celvir 450Mg Tablet contains Valganciclovir which works by getting converted to ganciclovir in the body and inhibits the multiplication of the virus. Thereby, it helps to control the infection.  

Take Celvir 450Mg Tablet as prescribed by your doctor. You are advised to take Celvir 450Mg Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience diarrhea, loss of appetite, cough, headache, stomach pain, nausea, fever, tiredness, or sinusitis (sinus infection). Most of these side effects of Celvir 450Mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Celvir 450Mg Tablet or any other medicines, please tell your doctor. Avoid taking Celvir 450Mg Tablet if you are pregnant as it may cause birth defects. If you are breastfeeding, do not take Celvir 450Mg Tablet as it may be excreted in human milk and cause adverse effects in the baby. Women are recommended to use effective contraceptive measures while taking Celvir 450Mg Tablet and for 30 days after treatment with Celvir 450Mg Tablet. Drive only if you are alert as Celvir 450Mg Tablet may cause dizziness, tiredness, drowsiness, shakiness, or confusion.

Uses of Celvir 450Mg Tablet

Cytomegalovirus (CMV) infection of the retina

Directions for Use

Take Celvir 450Mg Tablet with food or as prescribed by your doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it.

Medicinal Benefits

Celvir 450Mg Tablet contains Valganciclovir, an antiviral drug used to treat cytomegalovirus (CMV) infection of the retina of the eye in adult AIDS patients. Celvir 450Mg Tablet gets converted to ganciclovir in the body and inhibits the multiplication of the virus. Thereby, it helps to control the infection.  Additionally, Celvir 450Mg Tablet is used to prevent CMV infection in patients who received an organ transplant from a donor infected with CMV.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Celvir 450Mg Tablet

  • Diarrhoea
  • Loss of appetite
  • Cough
  • Headache
  • Stomach pain
  • Nausea
  • Fever
  • Tiredness
  • Sinusitis (sinus infection)

Drug Warnings

If you are allergic to Celvir 450Mg Tablet or any other medicines, please tell your doctor. If you have a low number of platelets, white blood cells or red blood cells and kidney problems, inform your doctor before taking Celvir 450Mg Tablet. Avoid taking Celvir 450Mg Tablet if you are pregnant as it may cause birth defects. If you are breastfeeding, do not take Celvir 450Mg Tablet as it may be excreted in human milk and cause adverse effects in the baby. Women are recommended to use effective contraceptive measures while taking Celvir 450Mg Tablet and 30 days after treatment with Celvir 450Mg Tablet. Men are advised to continue using contraceptive measures for 90 days after treatment with Celvir 450Mg Tablet. Drive only if you are alert as Celvir 450Mg Tablet may cause dizziness, tiredness, drowsiness, shakiness or confusion. If you are having blood dialysis or radiotherapy, please inform your doctor before taking Celvir 450Mg Tablet.

Drug-Drug Interactions

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ValganciclovirCidofovir
Critical
ValganciclovirAdalimumab
Severe

Drug-Drug Interactions

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ValganciclovirCidofovir
Critical
How does the drug interact with Celvir 450Mg Tablet:
Taking cidofovir with Celvir 450Mg Tablet can increase the risk of kidney problems.

How to manage the interaction:
Taking Celvir 450Mg Tablet with Cidofovir is not recommended as it can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
ValganciclovirAdalimumab
Severe
How does the drug interact with Celvir 450Mg Tablet:
The combined use of adalimumab and Celvir 450Mg Tablet can increase the risk of serious infections.

How to manage the interaction:
There may be a possibility of interaction between Celvir 450Mg Tablet and Adalimumab, but it can be taken if prescribed by a doctor. If you notice any of the following symptoms - fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain or burning while peeing - reach out to your doctor right away. Do not stop using any medications without talking to your doctor.
ValganciclovirCertolizumab
Severe
How does the drug interact with Celvir 450Mg Tablet:
Taking Celvir 450Mg Tablet and Certolizumab may increase the risk of serious infection.

How to manage the interaction:
Although there is a possible interaction between Celvir 450Mg Tablet and Certolizumab, you can take these medicines together if prescribed by your doctor. If you notice any of the following symptoms - fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain, or burning while urinating - contact your doctor right away. Do not discontinue any medications without consulting your doctor.
ValganciclovirDeferiprone
Severe
How does the drug interact with Celvir 450Mg Tablet:
Taking Celvir 450Mg Tablet and Deferiprone may increase the risk of severe infections.

How to manage the interaction:
There may be a possibility of interaction between Celvir 450Mg Tablet and Deferiprone, but it can be taken if prescribed by a doctor. If you're having any of these symptoms - like infection, fever, chills, diarrhea, sore throat, trouble breathing, losing weight, or pain while peeing - contact your doctor right away. Do not stop using any medications without a doctor's advice.
ValganciclovirEtanercept
Severe
How does the drug interact with Celvir 450Mg Tablet:
The combined use of etanercept and Celvir 450Mg Tablet can increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction between Celvir 450Mg Tablet and Etanercept, you can take these medicines together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
ValganciclovirMaribavir
Severe
How does the drug interact with Celvir 450Mg Tablet:
When Celvir 450Mg Tablet is used with Maribavir, it may make Celvir 450Mg Tablet less effective in treating your condition

How to manage the interaction:
Although there is a possible interaction between Celvir 450Mg Tablet and Maribavir, you can take these medicines together if prescribed by your doctor. If you're having any unusual symptoms, contact a doctor right away. Do not stop using any medications without talking to your doctor.
ValganciclovirTenofovir alafenamide
Severe
How does the drug interact with Celvir 450Mg Tablet:
When Celvir 450Mg Tablet is taken with Tenofovir alafenamide it may increase the risk of kidney problems.

How to manage the interaction:
Although taking Tenofovir alafenamide and Celvir 450Mg Tablet together can cause an interaction, it can be taken if your doctor has suggested it. However, consult your doctor immediately if you experience symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to your doctor.
ValganciclovirZidovudine
Severe
How does the drug interact with Celvir 450Mg Tablet:
Combining Celvir 450Mg Tablet with Zidovudine can increase the risk of side effects.

How to manage the interaction:
Although taking Celvir 450Mg Tablet and Zidovudine together can cause an interaction, it can be taken if your doctor has suggested it. If you experience any complications or symptoms, make sure to contact your doctor right away. Do not stop using any medications without a doctor's advice.
ValganciclovirGolimumab
Severe
How does the drug interact with Celvir 450Mg Tablet:
The combined use of golimumab and Celvir 450Mg Tablet can increase the risk of infections.

How to manage the interaction:
Although taking Celvir 450Mg Tablet and Golimumab together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any of the following symptoms - fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain or burning while peeing - contact your doctor right away. Do not stop using any medications without talking to your doctor.
ValganciclovirCladribine
Severe
How does the drug interact with Celvir 450Mg Tablet:
The combined use of cladribine and Celvir 450Mg Tablet can increase the risk of infections.

How to manage the interaction:
Taking Cladribine with Celvir 450Mg Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms - infection, fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain, or burning while urinating - contact your doctor right away. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as dark-green, yellow, orange, and red vegetables and fruits as it helps to boost your immune system. Opt for lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
  • Eat bland and low-fat foods and avoid spicy or oily foods if you experience nausea or vomiting.

Habit Forming

No

Therapeutic Class

ANTIVIRALS

Celvir 450Mg Tablet Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Celvir 450Mg Tablet contains Valganciclovir that works by getting converted to ganciclovir in the body and inhibits the multiplication of the virus. Thereby, it helps to control the infection.

Celvir 450Mg Tablet may be used to prevent cytomegalovirus infection in patients who received an organ transplant from a donor infected with CMV.

Celvir 450Mg Tablet may cause diarrhoea as a temporary side effect. However, if the condition persists or worsens, please consult a doctor.

Celvir 450Mg Tablet should be used with caution in patients with kidney problems and only in doses as prescribed by a doctor. However, regular blood tests are recommended while taking Celvir 450Mg Tablet to monitor kidney functioning.

You are not recommended to take Celvir 450Mg Tablet with tacrolimus (immunosuppressant) as it may increase the risk of kidney or nerve damage, cause side effects affecting bone marrow function leading to a low number of blood cells. Therefore, please consult a doctor before taking Celvir 450Mg Tablet with other medicines.

Drug-Drug Interactions Checker List

  • TRIMETHOPRIM
  • DAPSONE
  • PROBENECID
  • AMPHOTERICIN B
  • IMIPENEM+CILASTATIN
  • FLUCYTOSINE
  • PENTAMIDINE
  • VINBLASTINE
  • HYDROXYUREA
  • VINCRISTINE
  • DOXORUBICIN
  • TACROLIMUS
  • MYCOPHENOLATE MOFETIL
  • CICLOSPORIN
  • TENOFOVIR DISOPROXIL
  • ZIDOVUDINE
  • STAVUDINE
  • ADEFOVIR
  • DIDANOSINE

Special Advise

  • Regular eye tests are recommended if you have a history of cytomegalovirus retinitis to identify issues related to eye health.
  •  If you touch damaged tablets accidentally, wash your hands with soap and water thoroughly. If any powder from tablets gets into your eyes, rinse with sterile or clean water.

Disease/Condition Glossary

Cytomegalovirus (CMV) retinitis: It is a viral infection of the retina (light-sensing cells) caused by cytomegalovirus. In serious cases, it may lead to blindness. CMV retinitis is more likely to affect people with a weakened immune system from HIV/AIDS. The symptoms include blurred vision, a blind spot in vision, floaters in the eye, loss of peripheral vision or flashes in the eye.

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