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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Divya L , PharmaD
Non returnable*
COD available

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Composition :

TESTOSTERONE-1000MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Cernos Depot Injection 4 ml

Cernos Depot Injection 4 ml belongs to a group of medicines called androgens indicated for testosterone replacement therapy in adult men for conditions associated with a deficiency/absence of endogenous testosterone, such as primary hypogonadism and hypogonadotropic hypogonadism. 
 
Cernos Depot Injection 4 ml contains Testosterone, which helps replenish the deficient testosterone levels in adult men. Thereby, Cernos Depot Injection 4 ml helps in treating deficiency/absence of endogenous testosterone. Testosterone is the anabolic steroid and primary sex hormone in males, which plays an important role in developing male reproductive tissues like the prostate and testes.
 
Cernos Depot Injection 4 ml will be administered by a healthcare professional; do not self-administer. In some cases, you may experience side effects such as injection site reactions, polycythemia (high number of red blood cells), headache, and depression. You are advised to talk to your doctor if the side effects persist or worsen.
 
Let your doctor know if you are allergic to any of the components in Cernos Depot Injection 4 ml. Do not use Cernos Depot Injection 4 ml if you are pregnant or breastfeeding. Cernos Depot Injection 4 ml is not recommended for children below 12 years as safety and effectiveness have not been established. Keep your doctor informed about your health conditions and medications to rule out any side effects/interactions.

Uses of Cernos Depot Injection 4 ml

Testosterone replacement therapy.

Directions for Use

Cernos Depot Injection 4 ml will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Cernos Depot Injection 4 ml belongs to a group of medicines called androgens indicated for testosterone replacement therapy in adult men for conditions associated with a deficiency/absence of endogenous testosterone. Cernos Depot Injection 4 ml contains Testosterone, which helps replenish the deficient testosterone levels in adult men. Thereby, Cernos Depot Injection 4 ml helps in treating deficiency/absence of endogenous testosterone. 

Storage

Store in a cool and dry place away from sunlight
Side effects of Cernos Depot Injection 4 ml
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Managing Medication-Triggered Erythema (Redness of the Skin or Skin redness): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Injection site reaction can include numbness or redness.
  • Get a physical examination, follow your doctor's instructions, if it worsens or gets swollen.
  • Apply cold compress for pain relief.
  • Practice good hygiene and keep the injection site away from heat and pressure.
  • Apply pressure for 5-10 minutes to reduce bleeding.
  • Apply cold compresses or ice packs for 15-20 minutes, repeat every few hours.
  • Consult the doctor and use antihistamines if advised to minimise injection site reaction.
  • Use pain relief medication, like acetaminophen if recommended by the doctor, but avoid NSAIDs if bleeding is a concern.
  • Rotate injection sites and use proper needle size and technique if you are self-administering the medication.
  • Monitor signs such as increased pain, redness, warmth, or pus, and seek medical attention if symptoms worsen.
  • Always wear loose-fitting clothes suitable for your activity during hot flashes.
  • Include a diet containing fruits like watermelon, grapes, bananas and green leafy vegetables.
  • Drink plenty of water and stay hydrated.
  • Stay calm and lower your anxiety by practising yoga or meditation.

Drug Warnings

Do not take Cernos Depot Injection 4 ml if you are allergic to any of its contents; or if you have prostate cancer or breast cancer. Cernos Depot Injection 4 ml is not intended for use in women. Inform your doctor if you have a high blood cell count or high haemoglobin laboratory value, urinary problems due to an enlarged prostate, heart problems, diabetes, sleep apnoea (breathing problem while sleeping), or liver or kidney problems. Cernos Depot Injection 4 ml is not recommended for children below 12 years as safety and effectiveness have not been established. 

Drug-Drug Interactions

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TestosteroneMorphine
Severe
TestosteroneCarfilzomib
Severe

Drug-Drug Interactions

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TestosteroneMorphine
Severe
How does the drug interact with Cernos Depot Injection 4 ml:
Taking Cernos Depot Injection 4 ml with Morphine may increase the blood levels and side effects of morphine.

How to manage the interaction:
Co-administration of Morphine with Cernos Depot Injection 4 ml can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, tiredness, cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reduced reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.
TestosteroneCarfilzomib
Severe
How does the drug interact with Cernos Depot Injection 4 ml:
The combined use of Cernos Depot Injection 4 ml and Carfilzomib can increase the risk of blood clots.

How to manage the interaction:
Co-administration of Cernos Depot Injection 4 ml and Carfilzomib can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
TestosteroneLeflunomide
Severe
How does the drug interact with Cernos Depot Injection 4 ml:
Co-administration of Leflunomide and Cernos Depot Injection 4 ml can increase the risk of liver problems.

How to manage the interaction:
Although there is an interaction between leflunomide and Cernos Depot Injection 4 ml, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TestosteroneWarfarin
Severe
How does the drug interact with Cernos Depot Injection 4 ml:
Coadministration of Warfarin with Cernos Depot Injection 4 ml can increase the risk of unusual bleeding.

How to manage the interaction:
Although taking Cernos Depot Injection 4 ml and warfarin together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
TestosteroneLomitapide
Severe
How does the drug interact with Cernos Depot Injection 4 ml:
Co-administration of Lomitapide and Cernos Depot Injection 4 ml can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Lomitapide and Cernos Depot Injection 4 ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
TestosteroneLenalidomide
Severe
How does the drug interact with Cernos Depot Injection 4 ml:
Coadministration of Lenalidomide with Cernos Depot Injection 4 ml can increase levels of Cernos Depot Injection 4 ml in the blood.

How to manage the interaction:
Coadministration of Cernos Depot Injection 4 ml with Lenalidomide together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting your doctor.
TestosteronePazopanib
Severe
How does the drug interact with Cernos Depot Injection 4 ml:
Co-administration of Pazopanib with Cernos Depot Injection 4 ml may significantly increase the blood levels of pazopanib, which can develop serious side effects such as liver problems, irregular heart rhythm, bleeding, and high blood pressure

How to manage the interaction:
Co-administration of Pazopanib and Cernos Depot Injection 4 ml can lead to an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, and yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
TestosteroneBosentan
Moderate
How does the drug interact with Cernos Depot Injection 4 ml:
Bosentan may lower Cernos Depot Injection 4 ml levels in the blood and its effects.

How to manage the interaction:
Although using Bosentan and Cernos Depot Injection 4 ml together can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor if your condition worsens. Do not stop taking any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Tuna, egg yolks, fortified cereals, oysters, shell fish, and beans are good sources of Testosterone.
  • Maintain a healthy diet and exercise regularly.
  • Get ample rest and proper sleep.
  • Reduce stress levels by doing yoga or meditation. 
  • Consume foods that are rich in zinc, such as nuts, crab, beans, lobster, and whole grains.

Habit Forming

Yes

Therapeutic Class

ANABOLIC STEROID

Cernos Depot Injection 4 ml Substitute

Substitutes safety advice
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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Cernos Depot Injection 4 ml helps in replenishing the deficient testosterone levels in adult men. Thereby, helps in treating deficiency/absence of endogenous testosterone.

Cernos Depot Injection 4 ml should be used with caution in patients with benign prostatic hyperplasia (BPH) as they are at an increased risk for worsening of signs and symptoms of BPH.

Cernos Depot Injection 4 ml might increase the risk of prostate cancer. It is recommended to evaluate patients for prostate cancer prior to initiating and during the treatment with Cernos Depot Injection 4 ml.

Cernos Depot Injection 4 ml may cause changes in anticoagulant activity. Therefore, frequent monitoring of prothrombin time and International Normalised Ratio (INR) is advised.

Cernos Depot Injection 4 ml may cause venous thromboembolism (formation of a blood clot in the vein), including deep vein thrombosis (blood clot develops in a deep vein) and pulmonary embolism (blockage in the lung artery). Consult your doctor if you experience pain, oedema (swelling), warmth, and erythema (skin redness) in lower proximity or shortness of breath.

Drug-Drug Interactions Checker List

  • PROPRANOLOL

Special Advise

  • Regular monitoring of blood pressure, blood sugar levels, red blood cell count, and haemoglobin levels is advised.
  • Consult your doctor if you notice any signs and symptoms of a blood clot in your leg, such as pain, swelling or redness or signs and symptoms of a blood clot in your lungs, like difficulty breathing or chest pain.
  • Consult your doctor immediately if you have changes in mood or depression.

Disease/Condition Glossary

Testosterone replacement therapy: Testosterone replacement therapy, also known as androgen replacement therapy, is used to treat low levels of testosterone. Testosterone is the anabolic steroid and primary sex hormone in males, which plays an important role in the development of male reproductive tissues like the prostate and testes. Symptoms of low testosterone include reduced sex drive, erectile dysfunction, low/zero sperm count, loss of pubic/armpit hair, shrinking testicles, and hot flushes.

Primary hypogonadism: Primary hypogonadism is a condition in which the gonads (testes in men and ovaries in women) produce insufficient sex hormones. Sex hormones are responsible for secondary sexual characteristics, such as testicular development in men and breast development in women. Autoimmune disorders, genetic disorders, severe infections, pituitary disorders, and inflammatory diseases could be the causes of hypogonadism. Symptoms of hypogonadism include abnormal breast growth, erectile dysfunction, muscle loss, loss of body hair, osteoporosis, low sex drive, infertility, fatigue, hot flushing, and difficulty concentrating.

Hypogonadotropic hypogonadism: It is a form of hypogonadism that occurs due to a problem with the hypothalamus or pituitary gland. It is caused due to lack of the gonadotropin-releasing hormone, follicle-stimulating hormone (FSH), and luteinising hormone (LH). Damage to the pituitary gland, genetic defects, high prolactin levels, severe stress, nutritional problems, and certain medical conditions could be the causes of hypogonadotropic hypogonadism. 

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