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About Cilamin-250 Capsule
Cilamin-250 Capsule belongs to the group of medicines called ‘chelating agents’ used to treat severe rheumatoid arthritis, Wilsons disease, and cystinuria. Rheumatoid arthritis is a joint disorder in which our immune system attacks our body cells. Wilson disease is a genetic problem characterized by excess copper deposited in body parts like the eye, brain, and liver leading to metal toxicity. Cystinuria is the excess build-up of an amino acid called cystine in the urinary bladder and kidney, leading to harmful effects.
Cilamin-250 Capsule contains Penicillamine which works by blocking the action of certain chemical messengers responsible for inflammation and slows the progress of the condition with certain joint diseases. It works in Wilson's disease by binding to the extra copper in the body and causing it to leave the body through the urine. Decreasing copper levels improves liver function, and mental, mood, and nerve problems (like confusion, and difficulty speaking or walking) caused due to Wilson's disease. Besides this, Cilamin-250 Capsule is also used to treat cystinuria (kidney and bladder stone) and lead poisoning.
Take Cilamin-250 Capsule exactly as prescribed by your doctor. You are advised to take Cilamin-250 Capsule for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side effects such as protein in the urine, low blood platelets, stomach upset or throwing up, diarrhoea, change in taste, loss of appetite, mouth irritation, and mouth sores. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
To treat your condition effectually, continue taking Cilamin-250 Capsule for as long as your doctor has prescribed. To avoid recurring symptoms, do not stop it midway. Do not take Cilamin-250 Capsule if you are pregnant or planning for pregnancy as Cilamin-250 Capsule causes serious congenital disabilities. Cilamin-250 Capsule should not be taken by breastfeeding mothers as it passes into breast milk. Your doctor may advise you to undergo regular blood tests, and kidney and liver tests to monitor your condition. Inform your doctor about your health condition and medicines to rule out any unpleasant side effects.
Uses of Cilamin-250 Capsule
Directions for Use
Medicinal Benefits
Cilamin-250 Capsule contains Penicillamine primarily used to treat Wilson's disease (copper builds up in the body and may result in serious symptoms) and cystinuria (kidney stones). It is also used in combination with other treatments to treat severe rheumatoid arthritis. The treatment of rheumatoid arthritis Cilamin-250 Capsule reduces pain, inflammation, and slow joint damage and disease progression over time; hence Cilamin-250 Capsule is known as a disease-modifying anti-rheumatic drug (DMARD). In Wilson's disease, Cilamin-250 Capsule works by binding to the extra copper in the body and causing it to leave the body through the urine. Decreasing copper levels improves liver function and the mental, mood, and nerve problems (such as confusion, and difficulty speaking/walking) caused by Wilson's disease. In cystinuria, it helps decrease the amount of a certain substance (cystine) by binding to that substance which can cause kidney stones and prevent it from building up and forming stones. Besides this, Cilamin-250 Capsule is also used to treat lead poisoning.
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Drug Warnings
Do not take Cilamin-250 Capsule if you are allergic (hypersensitive) to penicillamine or any of the other ingredients in it. Inform your doctor if you have severe kidney problems, lupus erythematosus (an auto-immune disorder), agranulocytosis (a low white cell blood count), aplastic anaemia (symptoms including feeling tired, breathless, having pale skin and more susceptible to infection) or thrombocytopenia (a blood disorder which causes bleeding into your skin, bruising and bleeding more than normal). Do not take Cilamin-250 Capsule if you are pregnant or planning to get pregnant and breastfeeding. This medicine may cause harm to the unborn baby if you take it while you are pregnant. Caution should be required while taking Cilamin-250 Capsule by elderly patients as they may be at greater risk of suffering side effects if you are taking Cilamin-250 Capsule over a long time, especially if you are on a restricted diet, as this medicine increases the requirement for pyridoxine (Vitamin B6) so your doctor may also prescribe this vitamin for you. If you are taking iron tablets, antacids, or digoxin (used to treat heart failure), please maintain two hours gap between these tablets and Cilamin-250 Capsule . Low blood cell counts have happened while taking Cilamin-250 Capsule . If blood cell counts get very low, this can lead to bleeding problems, infections, or anaemia, and sometimes, these have been deadly.
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Cilamin-250 Capsule works by blocking the action of certain chemical messengers that are responsible for inflammation and prevents joint stiffness, thereby provides relief from rheumatoid arthritis.
Wilson’s disease is a condition where the body cannot get rid of copper properly and cause damage the liver, brain, and other organs. Cilamin-250 Capsule contains penicillamine that works by helping the body to remove excess copper.
Avoid taking other medicines at the same time while taking Cilamin-250 Capsule . If you take an iron supplement, take it at least 2 hours before or after you take Cilamin-250 Capsule . Iron can make it harder for your body to absorb Cilamin-250 Capsule . Avoid taking mineral supplements, unless your doctor advised you to. Do not drink milk within 1 hour before or after you take Cilamin-250 Capsule . Do not take copper-containing foods like shellfish, chocolate, nuts, mushroom, and organ meats (liver pate, sweetbreads etc.)
Cilamin-250 Capsule may cause side-effects such as protein in urine, low blood platelets, stomach upset or throwing up, diarrhea , change in taste, loss of appetite, mouth irritation, mouth sores. These side-effects are usually mild and temporary. However, if any of these side-effects persist or get worse, inform your doctor immediately.
Cilamin-250 Capsule should not be taken during pregnancy or if you are trying to become pregnant as Cilamin-250 Capsule can cause birth defects, miscarriages or harm unborn babies. Avoid becoming pregnant for at least 6 months after stopping the treatment with Cilamin-250 Capsule .
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Special Advise
Disease/Condition Glossary
Rheumatoid arthritis: It is an autoimmune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Symptoms of rheumatoid arthritis include pain, inflammation of joints, difficulty moving, and swelling.
Wilson’s disease: It is a rare genetic disorder that causes excess copper in the body. Copper plays an important role in developing healthy nerves, bones, collagen, and the skin pigment melanin. Normally, copper is absorbed from the food; the liver filters out excess copper and releases it through urine. In People with Wilson’s disease, the liver cannot remove the extra copper properly, and the extra copper then builds up in organs such as the brain, liver, and eyes.
Cystinuria: It is the condition in which the amino acid called cystine in the urine, leading to the formation of cystine stones in the kidneys, ureters, and bladder. Cystinuria symptoms are usually sharp pain in the lower back or side of the abdomen (renal colic), blood in the urine (hematuria), obstruction of the urinary tract, and infections of the urinary tract.
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Alcohol
Unsafe
You are recommended to avoid alcohol consumption while taking Cilamin-250 Capsule . It could lead to increased dizziness and drowsiness.
Pregnancy
Unsafe
Cilamin-250 Capsule is a pregnancy category D drug. It is not recommended to take Cilamin-250 Capsule while you are pregnant. Cilamin-250 Capsule may cause serious birth defects.
Breast Feeding
Unsafe
Cilamin-250 Capsule should not be used in breastfeeding mothers as Cilamin-250 Capsule passes into breast milk.
Driving
Caution
Cilamin-250 Capsule may cause dizziness, drowsiness and tiredness; do not drive or operate heavy machinery if you feel dizzy.
Liver
Unsafe
Cilamin-250 Capsule is not recommended for the liver patients.
Kidney
Caution
Cilamin-250 Capsule should be used with caution in patients with kidney diseases. Dose adjustments may be necessary.
Children
Safe if prescribed
Cilamin-250 Capsule should be used in children under the care of the doctor. The dose may depend on the weight and age of the child.