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Prescription drugWhats That
Composition
CEFIXIME-200MG + CLAVULANIC ACID-125MG
Manufacturer/Marketer
Zydus Pharma Ltd
Consume Type
ORAL
Return Policy
Not Returnable
Expires on or after
Apr-24
for this medicine
Drug-Drug Interactions
CefiximeCholera, live attenuated
Severe
Drug-Drug Interactions
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CefiximeCholera, live attenuated
Severe
How does the drug interact with Clavicef Tablet:
Co-administration of Clavicef Tablet with Cholera vaccine may reduce the effectiveness of the vaccine.
How to manage the interaction:
Talk to your doctor before receiving the cholera vaccine if you are currently being treated with Clavicef Tablet or have been treated within the last 14 days. To ensure adequate vaccine response, you should not receive cholera vaccine until at least 14 days after you complete your antibiotic therapy. Do not discontinue the medication without consulting a doctor.
Co-administration of Clavicef Tablet with Cholera vaccine may reduce the effectiveness of the vaccine.
How to manage the interaction:
Talk to your doctor before receiving the cholera vaccine if you are currently being treated with Clavicef Tablet or have been treated within the last 14 days. To ensure adequate vaccine response, you should not receive cholera vaccine until at least 14 days after you complete your antibiotic therapy. Do not discontinue the medication without consulting a doctor.
Drug-Food Interactions
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
Drug-Food Interactions
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Product Substitutes
Author Details
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Drug-Diseases Interactions
CEFIXIME-200MG+CLAVULANIC ACID-125MGOther bacterial intestinal infections
Severe
CEFIXIME-200MG+CLAVULANIC ACID-125MGDisorders resulting from impaired renal tubular function
Moderate
Drug-Diseases Interactions
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CEFIXIME-200MG+CLAVULANIC ACID-125MGOther bacterial intestinal infections
Severe
How does the disease interact with Clavicef Tablet:
Almost all antibacterial medications have been associated to reports of Clostridioides difficile-associated diarrhoea (CDAD), formerly known as pseudomembranous colitis. It can vary from mild diarrhoea to deadly colitis. Clindamycin and lincomycin are two of the most frequent offenders.
How to manage the interaction:
Antibiotics may cause Clostridioides difficile-associated diarrhoea (CDAD), which may range from mild diarrhoea to fatal colitis. Appropriate fluid and electrolyte management, protein supplementation, antibacterial treatment of C difficile, and surgical evaluation is advised.
Almost all antibacterial medications have been associated to reports of Clostridioides difficile-associated diarrhoea (CDAD), formerly known as pseudomembranous colitis. It can vary from mild diarrhoea to deadly colitis. Clindamycin and lincomycin are two of the most frequent offenders.
How to manage the interaction:
Antibiotics may cause Clostridioides difficile-associated diarrhoea (CDAD), which may range from mild diarrhoea to fatal colitis. Appropriate fluid and electrolyte management, protein supplementation, antibacterial treatment of C difficile, and surgical evaluation is advised.
CEFIXIME-200MG+CLAVULANIC ACID-125MGDisorders resulting from impaired renal tubular function
Moderate
How does the disease interact with Clavicef Tablet:
The kidneys remove the majority of beta-lactam antibiotics as unaltered drugs and, in certain situations, as metabolites as well. In individuals with poor renal function, the blood concentrations of beta-lactam antibiotics and their metabolites may rise and their half-lives may be prolonged. According to the particular product package labelling, dosage modifications may be required. These alterations should be based on the severity of the infection as well as the degree of renal impairment. Renal function tests should be carried out on a regular basis during extended and/or high-dose therapy since these medicines have occasionally been linked to nephrotoxicity and changes in renal function.
How to manage the interaction:
The serum concentration may be increased in patients with impaired kidney function as most beta-lactam antibiotics are eliminated by the kidney. Dose adjustment may be necessary for patients with kidney dysfunction. Regular renal function tests are advised.
The kidneys remove the majority of beta-lactam antibiotics as unaltered drugs and, in certain situations, as metabolites as well. In individuals with poor renal function, the blood concentrations of beta-lactam antibiotics and their metabolites may rise and their half-lives may be prolonged. According to the particular product package labelling, dosage modifications may be required. These alterations should be based on the severity of the infection as well as the degree of renal impairment. Renal function tests should be carried out on a regular basis during extended and/or high-dose therapy since these medicines have occasionally been linked to nephrotoxicity and changes in renal function.
How to manage the interaction:
The serum concentration may be increased in patients with impaired kidney function as most beta-lactam antibiotics are eliminated by the kidney. Dose adjustment may be necessary for patients with kidney dysfunction. Regular renal function tests are advised.
CEFIXIME-200MG+CLAVULANIC ACID-125MGAbnormal serum enzyme levels
Moderate
How does the disease interact with Clavicef Tablet:
Hepatitis cases have been associated to the usage of several cephalosporins. Alkaline phosphatase, AST, and ALT levels have all shown a brief spike. When these medications are provided to people with hepatic problems, caution and close observation are advised.
How to manage the interaction:
Caution and monitoring is recommended in patients with liver disorders.
Hepatitis cases have been associated to the usage of several cephalosporins. Alkaline phosphatase, AST, and ALT levels have all shown a brief spike. When these medications are provided to people with hepatic problems, caution and close observation are advised.
How to manage the interaction:
Caution and monitoring is recommended in patients with liver disorders.
CEFIXIME-200MG+CLAVULANIC ACID-125MGEpilepsy
Moderate
How does the disease interact with Clavicef Tablet:
It has been suggested that cephalosporins can cause seizures. In particular in patients with a history of epilepsy and/or where prescribed doses of cephalosporins were exceeded because of renal impairment, cephalosporins have been associated with nonconvulsive status epilepticus (NCSE), encephalopathy, coma, asterixis, neuromuscular excitability, and myoclonia. Depending on the creatinine clearance, change the dosage. In individuals with known seizure disorders, anticonvulsant medication should be maintained. Patients should get a neurological exam to see if medication should be stopped if CNS side effects like seizures happen.
How to manage the interaction:
Cephalosporin antibiotics may trigger seizures. Dose adjustment may be needed.
It has been suggested that cephalosporins can cause seizures. In particular in patients with a history of epilepsy and/or where prescribed doses of cephalosporins were exceeded because of renal impairment, cephalosporins have been associated with nonconvulsive status epilepticus (NCSE), encephalopathy, coma, asterixis, neuromuscular excitability, and myoclonia. Depending on the creatinine clearance, change the dosage. In individuals with known seizure disorders, anticonvulsant medication should be maintained. Patients should get a neurological exam to see if medication should be stopped if CNS side effects like seizures happen.
How to manage the interaction:
Cephalosporin antibiotics may trigger seizures. Dose adjustment may be needed.
