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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Composition

ENOXAPARIN-20MG

Manufacturer/Marketer

Sanofi India Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Clexane 20mg Injection

Clexane 20mg Injection belongs to a class of medications known as blood thinners or anticoagulants. It helps to treat harmful blood clots in your blood. Furthermore, Clexane 20mg Injection can prevent or treat blood clots caused by a variety of medical conditions, such as unstable angina, after an operation or long periods of bed rest due to illness, after a heart attack, and blood clots forming in your dialysis machine's tubes. A blood clot is a mass of blood that forms when platelets, proteins, and cells in the blood stick together. A blood clot can occur in any body part, leading to a heart attack, stroke, and organ damage (even coma or death).

Clexane 20mg Injection contains Enoxaparin, which is low molecular weight heparin. Clexane 20mg Injection works by preventing existing blood clots from growing larger, allowing your body to break them down and prevent them from harming you. On the other hand, it inhibits the formation of new blood clots in your blood.

Clexane 20mg Injection will be administered by a healthcare professional; do not self-administer. You may experience bleeding, increased liver enzymes, skin rash (hives, urticaria), itchy red skin, bruising or pain at the injection site, and headache as side effects of Clexane 20mg Injection . Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, report to your doctor immediately. 

If you are known to be allergic to Clexane 20mg Injection or any other medicines, inform your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before receiving the Clexane 20mg Injection . Also, disclose to your doctor if you have any pre-existing medical conditions like a stomach ulcer, recent surgery of the brain or eyes or spine, recent bleeding stroke, diabetes, high blood pressure, or recent onset of stroke or kidney or liver disorders. And also, let your doctor know if you are underweight or overweight or if you have high levels of potassium in your blood.

Uses of Clexane 20mg Injection

Treatment and prevention of blood clots

Directions for Use

Clexane 20mg Injection will be administered by a qualified healthcare professional. Kindly do not self-administer.

Medicinal Benefits

Clexane 20mg Injection contains Enoxaparin, which is low molecular weight heparin or LMWH. It helps to treat harmful blood clots that are in your blood. Besides, this Clexane 20mg Injection can stop blood clots due to several medical conditions, including unstable angina, after an operation or long periods of bed rest due to illness, after a heart attack, and blood clots forming in the tubes of your dialysis machine. Clexane 20mg Injection works by stopping existing blood clots from getting any bigger; this helps your body to break them down and prevents them from causing you harm. On the other hand, it stops new blood clots from forming in your blood.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Clexane 20mg Injection

  • Bleeding
  • Increases in liver enzymes
  • Bruise more easily than usual
  • Pink patches on your skin 
  • Skin rash (hives, urticaria)
  • Itchy red skin
  • Bruising or pain at the injection site
  • Decreased red blood cell count
  • High platelet counts in the blood
  • Headache

Drug Warnings

Patients should inform the doctor if they are on active treatment with this Clexane 20mg Injection before any surgery is scheduled. If you are known to be allergic to Clexane 20mg Injection or any other medicines, inform your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using the Clexane 20mg Injection . Before using this Clexane 20mg Injection , disclose to your doctor if you have any pre-existing medical conditions like stomach ulcer, recent surgery of the brain or eyes or spine, recent bleeding stroke, diabetes, high blood pressure, or recent onset of stroke or kidney or liver disorders, And also let your doctor know if you are underweight or overweight or if you have high levels of potassium in your blood.

Drug-Drug Interactions

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EnoxaparinDefibrotide
Critical
EnoxaparinMifepristone
Critical

Drug-Drug Interactions

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EnoxaparinDefibrotide
Critical
How does the drug interact with Clexane 20mg Injection 0.2 ml:
Combining Defibrotide with Clexane 20mg Injection 0.2 ml can increase the risk of bleeding.

How to manage the interaction:
Taking Clexane 20mg Injection 0.2 ml with Defibrotide is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
EnoxaparinMifepristone
Critical
How does the drug interact with Clexane 20mg Injection 0.2 ml:
Combining Mifepristone with Clexane 20mg Injection 0.2 ml can increase the risk or severity of side effects of vaginal bleeding.

How to manage the interaction:
Taking Clexane 20mg Injection 0.2 ml with Mifepristone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience prolonged, excessive bleeding, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
EnoxaparinClopidogrel
Severe
How does the drug interact with Clexane 20mg Injection 0.2 ml:
Taking Clexane 20mg Injection 0.2 ml with clopidogrel can increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between clopidogrel and Clexane 20mg Injection 0.2 ml, but they can be taken together if prescribed by a doctor. However, If you experience any unusual bleeding or have other signs of bleeding like feeling dizzy or lightheaded, red or black, sticky stools, or headache, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
EnoxaparinEtodolac
Severe
How does the drug interact with Clexane 20mg Injection 0.2 ml:
Taking Etodolac with Clexane 20mg Injection 0.2 ml can increase the risk of bleeding and hemorrhage.

How to manage the interaction:
Co-administration of Etodolac with Clexane 20mg Injection 0.2 ml can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these signs like difficulty with bleeding, bleeding, bruising, swelling, throwing up, headache, feeling lightheaded, weakness, or seeing blood in your urine or stools it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
EnoxaparinRuxolitinib
Severe
How does the drug interact with Clexane 20mg Injection 0.2 ml:
Taking Clexane 20mg Injection 0.2 ml with ruxolitinib can increase the risk or severity of bleeding.

How to manage the interaction:
Taking Clexane 20mg Injection 0.2 ml with Ruxolitinib together can result in an interaction, but it can be taken if your doctor has advised it. If you notice any symptoms like bleeding, bruising, dizziness, severe headaches, black or tarry stools, weakness, and vomiting other symptoms to watch out for include black or tarry stools, weakness, and vomiting. Do not discontinue any medications without consulting a doctor.
EnoxaparinIbrutinib
Severe
How does the drug interact with Clexane 20mg Injection 0.2 ml:
Co-administration of Ibrutinib with Clexane 20mg Injection 0.2 ml can increase the risk or severity of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Ibrutinib and Clexane 20mg Injection 0.2 ml, but it can be taken if prescribed by a doctor. If you have any symptoms like unusual bleeding or bruising, dizziness, black or bloody stools, coughing up blood, vomiting blood, severe headache, or weakness, contact a doctor immediately. Do not stop using any medications without a doctor's advice.
EnoxaparinSulindac
Severe
How does the drug interact with Clexane 20mg Injection 0.2 ml:
Taking Sulindac with Clexane 20mg Injection 0.2 ml can increase the risk or severity of bleeding.

How to manage the interaction:
Coadministration of Clexane 20mg Injection 0.2 ml with Sulindac can result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these signs of difficulty with bleeding, bleeding, bruising, swelling, throwing up, headache, feeling lightheaded, weakness, or seeing blood in your urine or stools, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
EnoxaparinIndometacin
Severe
How does the drug interact with Clexane 20mg Injection 0.2 ml:
Using Indomethacin with Clexane 20mg Injection 0.2 ml can increase the risk of bleeding and hemorrhage.

How to manage the interaction:
Taking Indometacin with Clexane 20mg Injection 0.2 ml together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
EnoxaparinPhenylbutazone
Severe
How does the drug interact with Clexane 20mg Injection 0.2 ml:
Taking Clexane 20mg Injection 0.2 ml together with phenylbutazone can increase the risk or severity of bleeding complications.

How to manage the interaction:
Although taking Clexane 20mg Injection 0.2 ml and Phenylbutazone together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any of these signs like difficulty with bleeding, bleeding, bruising, swelling, throwing up, headache, feeling lightheaded, weakness, or blood in your urine or stools it's important to contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EnoxaparinWarfarin
Severe
How does the drug interact with Clexane 20mg Injection 0.2 ml:
Coadministration of Warfarin with Clexane 20mg Injection 0.2 ml can increase the risk or severity of bledding.

How to manage the interaction:
There may be a possible interaction between Clexane 20mg Injection 0.2 ml and Warfarin, but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A low cholesterol diet and a regular exercise regime complement treatment with Clexane 20mg Injection effectively.
  • As a precautionary measure, you are recommended not to consume alcohol, or junk food items from outside, stick to a freshly prepared home-cooked meal and rest properly for a speedy recovery.
  • And also, trying to replace most of your saturated fats with unsaturated fats can reduce total cholesterol and LDL in a short time.
  • Foods like avocados, olive oil, fatty fish, and nuts contain many heart-healthy unsaturated fats, so eating them regularly is beneficial.
  • Option for foods high in vitamin K (liver, leafy green vegetables, or vegetable oils) as Clexane 20mg Injection may lower Vitamin K in your body.
  • Avoid drinking alcohol as it increases the risk of gastrointestinal ulcer/bleeding.
  • Cranberry juice, grapefruit juice, noni juice, and pomegranate juice may interact with Clexane 20mg Injection and lead to unwanted side effects. Hence try to avoid these juices while taking Clexane 20mg Injection .

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

Clexane 20mg Injection Substitute

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ASPIRIN
  • IBUPROFEN
  • HEPARIN
  • WARFARIN
  • RIVAROXABAN
  • DEXTRAN INJECTION
  • PREDNISOLONE
  • DEXAMETHASONE

Special Advise

Regular blood tests are advised while taking Clexane 20mg Injection to monitor prothrombin, platelets, and coagulation time on a regular basis.

Disease/Condition Glossary

A blood clot can occur in any part of the body, leading to a heart attack, stroke, and damage to organs (even coma or death). Blood clots can reach your arteries or veins in the organs like the brain, kidney, heart, lungs, and limbs. Conditions like atherosclerosis, diabetes, heart failure, irregular heartbeat (arrhythmia), and obesity/overweight can trigger excessive blood clotting in the brain and heart. On the other hand, deep vein thrombosis (blood clot in veins), peripheral artery disease (narrowed arteries due to fat deposit or blood clot), and atherosclerosis (fat built upon the walls of the arteries) can cause a blood clot in your limbs.

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