Clexane 60 Injection 0.6 ml

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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

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MRP ₹705

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About Clexane 60 Injection

Clexane 60 Injection belongs to a class of medications known as blood thinners or anticoagulants. It helps to treat harmful blood clots in your blood. Furthermore, Clexane 60 Injection can prevent or treat blood clots caused by a variety of medical conditions, such as unstable angina, after an operation or long periods of bed rest due to illness, after a heart attack, and blood clots forming in your dialysis machine's tubes. A blood clot is a mass of blood that forms when platelets, proteins, and cells in the blood stick together. A blood clot can occur in any body part, leading to a heart attack, stroke, and organ damage (even coma or death).

Clexane 60 Injection contains Enoxaparin, which is low molecular weight heparin. Clexane 60 Injection works by preventing existing blood clots from growing larger, allowing your body to break them down and prevent them from harming you. On the other hand, it inhibits the formation of new blood clots in your blood.

Clexane 60 Injection will be administered by a healthcare professional; do not self-administer. You may experience bleeding, increased liver enzymes, skin rash (hives, urticaria), itchy red skin, bruising or pain at the injection site, and headache as side effects of Clexane 60 Injection . Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, report to your doctor immediately.

If you are known to be allergic to Clexane 60 Injection or any other medicines, inform your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before receiving the Clexane 60 Injection . Also, disclose to your doctor if you have any pre-existing medical conditions like a stomach ulcer, recent surgery of the brain or eyes or spine, recent bleeding stroke, diabetes, high blood pressure, or recent onset of stroke or kidney or liver disorders. And also, let your doctor know if you are underweight or overweight or if you have high levels of potassium in your blood.

Uses of Clexane 60 Injection

Treatment and prevention of blood clots

Directions for Use

Clexane 60 Injection will be administered by a qualified healthcare professional. Kindly do not self-administer.

Medicinal Benefits

Clexane 60 Injection contains Enoxaparin, which is low molecular weight heparin or LMWH. It helps to treat harmful blood clots that are in your blood. Besides, this Clexane 60 Injection can stop blood clots due to several medical conditions, including unstable angina, after an operation or long periods of bed rest due to illness, after a heart attack, and blood clots forming in the tubes of your dialysis machine. Clexane 60 Injection works by stopping existing blood clots from getting any bigger; this helps your body to break them down and prevents them from causing you harm. On the other hand, it stops new blood clots from forming in your blood.

Storage

Do not freeze

Side effects of Clexane 60 Injection 0.6 ml

Low Platelet Count

Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
If you experience severe bleeding or bruising, seek emergency medical attention immediately.

Asymptomatic Increase In Alanine Transaminase

Follow a balanced diet by including fruits, vegetables, and whole grains.
Increase fibre intake as it aids toxin removal.
Avoid processed foods and sugary drinks.
Aim for moderate-intensity exercise for most days of the week.
Quit smoking, as it can worsen liver health.
Manage stress with meditation or yoga.
Monitor liver function through regular blood tests.

Aspartate Aminotransferase Increased Asymptomatically

Consume more fruits, vegetables, and cruciferous foods like cabbage, kale, and broccoli.
Reduced alcohol intake can enhance liver enzyme function.
Oxidative stress can be managed by eating foods rich in antioxidants, such as vitamins C and E.
Liver function tests regularly can help manage increased levels of AST.

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Bruised Injection Site

Apply pressure for 5-10 minutes to reduce bleeding.
Apply cold compresses or ice packs for 15-20 minutes, repeat every few hours.
Consult the doctor and use antihistamines if advised to minimise injection site reaction.
Use pain relief medication, like acetaminophen if recommended by the doctor, but avoid NSAIDs if bleeding is a concern.
Rotate injection sites and use proper needle size and technique if you are self-administering the medication.
Monitor signs such as increased pain, redness, warmth, or pus, and seek medical attention if symptoms worsen.

Injection Site Reaction

Injection site reaction can include numbness or redness.
Get a physical examination, follow your doctor's instructions, if it worsens or gets swollen.
Apply cold compress for pain relief.
Practice good hygiene and keep the injection site away from heat and pressure.

Drug Warnings

Patients should inform the doctor if they are on active treatment with this Clexane 60 Injection before any surgery is scheduled. If you are known to be allergic to Clexane 60 Injection or any other medicines, inform your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using the Clexane 60 Injection . Before using this Clexane 60 Injection , disclose to your doctor if you have any pre-existing medical conditions like stomach ulcer, recent surgery of the brain or eyes or spine, recent bleeding stroke, diabetes, high blood pressure, or recent onset of stroke or kidney or liver disorders, And also let your doctor know if you are underweight or overweight or if you have high levels of potassium in your blood.

Drug-Drug Interactions

EnoxaparinDefibrotide

Critical

EnoxaparinMifepristone

Critical

Drug-Drug Interactions

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EnoxaparinDefibrotide

Critical

How does the drug interact with Clexane 60 Injection 0.6 ml:
Combining Defibrotide with Clexane 60 Injection 0.6 ml can increase the risk of bleeding.

How to manage the interaction:
Taking Clexane 60 Injection 0.6 ml with Defibrotide is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.

EnoxaparinMifepristone

Critical

How does the drug interact with Clexane 60 Injection 0.6 ml:
Combining Mifepristone with Clexane 60 Injection 0.6 ml can increase the risk or severity of side effects of vaginal bleeding.

How to manage the interaction:
Taking Clexane 60 Injection 0.6 ml with Mifepristone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience prolonged, excessive bleeding, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.

EnoxaparinHeparin

Severe

How does the drug interact with Clexane 60 Injection 0.6 ml:
Taking Heparin with Clexane 60 Injection 0.6 ml may increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Heparin and Clexane 60 Injection 0.6 ml, but it can be taken if prescribed by a doctor. However, consult a doctor, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop using any medications without a doctor's advice.

EnoxaparinFenoprofen

Severe

How does the drug interact with Clexane 60 Injection 0.6 ml:
Combining Fenoprofen with Clexane 60 Injection 0.6 ml can increase the risk of bleeding and hemorrhage.

How to manage the interaction:
There may be a possibility of interaction between Fenoprofen and Clexane 60 Injection 0.6 ml, but it can be taken if advised by a doctor. If you notice any symptoms like bruising, swelling, vomiting, headache, blood in your urine or stools, dizziness, or weakness make sure to contact a doctor immediately. Do not stop using any medications without a doctor's advice.

EnoxaparinIbrutinib

Severe

How does the drug interact with Clexane 60 Injection 0.6 ml:
Co-administration of Ibrutinib with Clexane 60 Injection 0.6 ml can increase the risk or severity of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Ibrutinib and Clexane 60 Injection 0.6 ml, but it can be taken if prescribed by a doctor. If you have any symptoms like unusual bleeding or bruising, dizziness, black or bloody stools, coughing up blood, vomiting blood, severe headache, or weakness, contact a doctor immediately. Do not stop using any medications without a doctor's advice.

EnoxaparinPiroxicam

Severe

How does the drug interact with Clexane 60 Injection 0.6 ml:
Taking Piroxicam with Clexane 60 Injection 0.6 ml can increase the risk or severity of bleeding.

How to manage the interaction:
Although there is a possible interaction between Clexane 60 Injection 0.6 ml and Piroxicam, you can take these medicines together if prescribed by your doctor. If you notice any of these signs, it's important to contact a doctor right away: bleeding, bruising, swelling, throwing up, headache, feeling lightheaded, weakness, or seeing blood in your urine or stools. Do not discontinue any medications without consulting a doctor.

EnoxaparinFondaparinux

Severe

How does the drug interact with Clexane 60 Injection 0.6 ml:
Taking fondaparinux with Clexane 60 Injection 0.6 ml can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Fondaparinux and Clexane 60 Injection 0.6 ml, you can take these medicines together if prescribed by your doctor. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

EnoxaparinVorapaxar

Severe

How does the drug interact with Clexane 60 Injection 0.6 ml:
Combining Vorapaxar with Clexane 60 Injection 0.6 ml can increase the risk of bleeding and hemorrhage.

How to manage the interaction:
Co-administration of Clexane 60 Injection 0.6 ml with Vorapaxar can result in an interaction, but it can be taken if your doctor has advised it. If you are taking other medications that also increase the risk of bleeding, like blood thinners, the risk can be even higher. If you notice any of these symptoms like back pain, numbness, constipation, bleeding, severe headaches, or vomiting it's important to call a doctor right away. Do not stop using any medications without a doctor's advice.

EnoxaparinAspirin

Severe

How does the drug interact with Clexane 60 Injection 0.6 ml:
Using Clexane 60 Injection 0.6 ml along with aspirin, may enhance the risk of bleeding problems.

How to manage the interaction:
Although there is a possible interaction between aspirin and Clexane 60 Injection 0.6 ml, you can take these medicines together if prescribed by a doctor. However, if you notice unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness while taking these drugs, inform a doctor immediately. Do not stop using any medications without consulting a doctor.

EnoxaparinDiclofenac

Severe

How does the drug interact with Clexane 60 Injection 0.6 ml:
Taking Diclofenac with Clexane 60 Injection 0.6 ml can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between Diclofenac and Clexane 60 Injection 0.6 ml, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

A low cholesterol diet and a regular exercise regime complement treatment with Clexane 60 Injection effectively.
As a precautionary measure, you are recommended not to consume alcohol, or junk food items from outside, stick to a freshly prepared home-cooked meal and rest properly for a speedy recovery.
And also, trying to replace most of your saturated fats with unsaturated fats can reduce total cholesterol and LDL in a short time.
Foods like avocados, olive oil, fatty fish, and nuts contain many heart-healthy unsaturated fats, so eating them regularly is beneficial.
Option for foods high in vitamin K (liver, leafy green vegetables, or vegetable oils) as Clexane 60 Injection may lower Vitamin K in your body.
Avoid drinking alcohol as it increases the risk of gastrointestinal ulcer/bleeding.
Cranberry juice, grapefruit juice, noni juice, and pomegranate juice may interact with Clexane 60 Injection and lead to unwanted side effects. Hence try to avoid these juices while taking Clexane 60 Injection .

Side Effects of Clexane 60 Injection

Bleeding
Increases in liver enzymes
Bruise more easily than usual
Pink patches on your skin
Skin rash (hives, urticaria)
Itchy red skin
Bruising or pain at the injection site
Decreased red blood cell count
High platelet counts in the blood
Headache

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Clexane 60 Injection work?

Clexane 60 Injection contains Enoxaparin, which is low molecular weight heparin or LMWH. Clexane 60 Injection works by stopping existing blood clots from getting any bigger. This helps your body to break them down and prevents them from causing you harm. On the other hand, it stops new blood clots from forming in your blood.

Does the dose of Clexane 60 Injection vary based on body composition?

Yes, this Clexane 60 Injection is given based on your age and body weight. If you have low body weight, the chances of increased risk of bleeding are high, so mostly low doses are prescribed by your doctor. You may be monitored closely for signs of clot formation.

Can I take this Clexane 60 Injection if I have stomach ulcer?

No, do not take this Clexane 60 Injection if you have a stomach ulcer. Please inform your doctor about this condition before receiving it.

Does Clexane 60 Injection cause bleeding?

Yes, Clexane 60 Injection may cause bleeding. If you notice purple spots on the skin or unusual bruising, blood in urine, black tarry stools, or unusual bleeding from the gums or nose, please inform your doctor immediately as these are signs of bleeding more easily.

Does Clexane 60 Injection cause increases in liver enzymes?

Increases in liver enzymes are the most common side effect with Clexane 60 Injection . Regular lipid profile tests are recommended to avoid any additional complications.

Drug-Drug Interactions Checker List

ASPIRIN
IBUPROFEN
HEPARIN
WARFARIN
RIVAROXABAN
DEXTRAN INJECTION
PREDNISOLONE
DEXAMETHASONE

Special Advise

Regular blood tests are advised while taking Clexane 60 Injection to monitor prothrombin, platelets, and coagulation time on a regular basis.

Disease/Condition Glossary

A blood clot can occur in any part of the body, leading to a heart attack, stroke, and damage to organs (even coma or death). Blood clots can reach your arteries or veins in the organs like the brain, kidney, heart, lungs, and limbs. Conditions like atherosclerosis, diabetes, heart failure, irregular heartbeat (arrhythmia), and obesity/overweight can trigger excessive blood clotting in the brain and heart. On the other hand, deep vein thrombosis (blood clot in veins), peripheral artery disease (narrowed arteries due to fat deposit or blood clot), and atherosclerosis (fat built upon the walls of the arteries) can cause a blood clot in your limbs.