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Drug-Drug Interactions
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Severe
Drug-Drug Interactions
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Severe
How does the drug interact with Clindacef 300mg Capsule:
Co-administration of Clindacef 300mg Capsule with Atracurium can increase the risk of muscle weakness.
How to manage the interaction:
Taking Clindacef 300mg Capsule with Atracurium together can possibly result in an interaction, but it can be taken if a doctor has advised it. "Clindacef 300mg Capsule can affect the muscles and nerves in your body. When used with other medications that also affect the muscles and nerves, it can cause a serious problem called neuromuscular blockade. If you have trouble breathing or can't breathe at all, please call your doctor right away." Do not stop using any medications without a doctor's advice.
Co-administration of Clindacef 300mg Capsule with Atracurium can increase the risk of muscle weakness.
How to manage the interaction:
Taking Clindacef 300mg Capsule with Atracurium together can possibly result in an interaction, but it can be taken if a doctor has advised it. "Clindacef 300mg Capsule can affect the muscles and nerves in your body. When used with other medications that also affect the muscles and nerves, it can cause a serious problem called neuromuscular blockade. If you have trouble breathing or can't breathe at all, please call your doctor right away." Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Clindacef 300mg Capsule:
Co-administration of Carbamazepine and Clindacef 300mg Capsule together may result in reduced blood levels of Clindacef 300mg Capsule, which could make it less effective in treating your disease.
How to manage the interaction:
Although taking carbamazepine and Clindacef 300mg Capsule together can possibly result in an interaction, it can be taken if a doctor has prescribed it. If you experience any symptoms like fever, it is advised to consult a doctor. Without consulting a doctor, never stop taking any medications.
Co-administration of Carbamazepine and Clindacef 300mg Capsule together may result in reduced blood levels of Clindacef 300mg Capsule, which could make it less effective in treating your disease.
How to manage the interaction:
Although taking carbamazepine and Clindacef 300mg Capsule together can possibly result in an interaction, it can be taken if a doctor has prescribed it. If you experience any symptoms like fever, it is advised to consult a doctor. Without consulting a doctor, never stop taking any medications.
Severe
How does the drug interact with Clindacef 300mg Capsule:
Co-administration of Clindacef 300mg Capsule with Balsalazide may reduce the effectiveness of Balsalazide.
How to manage the interaction:
Although there is a possible interaction, Clindacef 300mg Capsule can be taken with balsalazide if prescribed by the doctor. Consult the prescriber if you have any concerns, the doctor may prescribe alternatives that do not interact, dose adjustment, or more frequent monitoring to safely use both medications. Do not discontinue the medication without consulting a doctor.
Co-administration of Clindacef 300mg Capsule with Balsalazide may reduce the effectiveness of Balsalazide.
How to manage the interaction:
Although there is a possible interaction, Clindacef 300mg Capsule can be taken with balsalazide if prescribed by the doctor. Consult the prescriber if you have any concerns, the doctor may prescribe alternatives that do not interact, dose adjustment, or more frequent monitoring to safely use both medications. Do not discontinue the medication without consulting a doctor.
Severe
How does the drug interact with Clindacef 300mg Capsule:
Co-administration of of Clindacef 300mg Capsule with gentamicin may increase the risk of kidney and/or nerve damage.
How to manage the interaction:
Although there is a possible interaction, Clindacef 300mg Capsule can be taken with gentamicin if prescribed by the doctor. Consult the prescriber if you experience signs and symptoms of kidney damage such as sudden weight gain or weight loss, nausea, vomiting, fluid retention, loss of appetite, increased or decreased urination, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. If you develop diarrhea or vomiting during treatment with these medications, drink plenty of fluids to prevent dehydration, as dehydration may also harm the kidney.
Co-administration of of Clindacef 300mg Capsule with gentamicin may increase the risk of kidney and/or nerve damage.
How to manage the interaction:
Although there is a possible interaction, Clindacef 300mg Capsule can be taken with gentamicin if prescribed by the doctor. Consult the prescriber if you experience signs and symptoms of kidney damage such as sudden weight gain or weight loss, nausea, vomiting, fluid retention, loss of appetite, increased or decreased urination, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. If you develop diarrhea or vomiting during treatment with these medications, drink plenty of fluids to prevent dehydration, as dehydration may also harm the kidney.
How does the drug interact with Clindacef 300mg Capsule:
Taking Clindacef 300mg Capsule with Botulinum toxin can increase the risk or severity of side effects.
How to manage the interaction:
Taking Clindacef 300mg Capsule with Botulinum toxin together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Taking Clindacef 300mg Capsule with Botulinum toxin can increase the risk or severity of side effects.
How to manage the interaction:
Taking Clindacef 300mg Capsule with Botulinum toxin together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClindamycinCholera, live attenuated
Severe
How does the drug interact with Clindacef 300mg Capsule:
Co-administration of Clindacef 300mg Capsule may reduce the activity of the cholera vaccine.
How to manage the interaction:
Talk to your doctor before receiving the Cholera vaccine if you are currently being treated with Clindacef 300mg Capsule or have been treated within the last 14 days. To ensure adequate vaccine response, you should not receive cholera vaccine until at least 14 days after you complete antibiotic therapy. Do not discontinue the medication without consulting a doctor.
Co-administration of Clindacef 300mg Capsule may reduce the activity of the cholera vaccine.
How to manage the interaction:
Talk to your doctor before receiving the Cholera vaccine if you are currently being treated with Clindacef 300mg Capsule or have been treated within the last 14 days. To ensure adequate vaccine response, you should not receive cholera vaccine until at least 14 days after you complete antibiotic therapy. Do not discontinue the medication without consulting a doctor.
Severe
How does the drug interact with Clindacef 300mg Capsule:
Concomitant use of Clindacef 300mg Capsule with indinavir may increase the effects of Clindacef 300mg Capsule.
How to manage the interaction:
Although there is a possible interaction, Clindacef 300mg Capsule can be taken with indinavir if prescribed by the doctor. Consult the prescriber if you experience persistent vomiting, nausea, abdominal pain, or diarrhoea.
Concomitant use of Clindacef 300mg Capsule with indinavir may increase the effects of Clindacef 300mg Capsule.
How to manage the interaction:
Although there is a possible interaction, Clindacef 300mg Capsule can be taken with indinavir if prescribed by the doctor. Consult the prescriber if you experience persistent vomiting, nausea, abdominal pain, or diarrhoea.
How does the drug interact with Clindacef 300mg Capsule:
Taking Clindacef 300mg Capsule with clarithromycin may increase the effects of Clindacef 300mg Capsule.
How to manage the interaction:
Although there is a possible interaction, Clindacef 300mg Capsule can be taken with clarithromycin if prescribed by the doctor. Consult the prescriber if you experience persistent vomiting, nausea, abdominal pain, or diarrhea. Do not discontinue the medication without consulting a doctor.
Taking Clindacef 300mg Capsule with clarithromycin may increase the effects of Clindacef 300mg Capsule.
How to manage the interaction:
Although there is a possible interaction, Clindacef 300mg Capsule can be taken with clarithromycin if prescribed by the doctor. Consult the prescriber if you experience persistent vomiting, nausea, abdominal pain, or diarrhea. Do not discontinue the medication without consulting a doctor.
Severe
How does the drug interact with Clindacef 300mg Capsule:
Coadministration of use of Clindacef 300mg Capsule with ketoconazole can increase the effects of Clindacef 300mg Capsule.
How to manage the interaction:
Although there is a possible interaction, Clindacef 300mg Capsule can be taken with ketoconazole if prescribed by the doctor. Consult the prescriber if you experience persistent vomiting, nausea, abdominal pain or diarrhea. Do not discontinue any medication without consulting a doctor. Do not discontinue any medication without consulting a doctor.
Coadministration of use of Clindacef 300mg Capsule with ketoconazole can increase the effects of Clindacef 300mg Capsule.
How to manage the interaction:
Although there is a possible interaction, Clindacef 300mg Capsule can be taken with ketoconazole if prescribed by the doctor. Consult the prescriber if you experience persistent vomiting, nausea, abdominal pain or diarrhea. Do not discontinue any medication without consulting a doctor. Do not discontinue any medication without consulting a doctor.
ClindamycinAmprenavir
Severe
How does the drug interact with Clindacef 300mg Capsule:
Co-administration of Amprenavir together with Clindacef 300mg Capsule can increase the effects of Clindacef 300mg Capsule.
How to manage the interaction:
Co-administration of Clindacef 300mg Capsule with Amprenavir can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have ongoing feelings of sickness, throwing up, having loose stools, or pain in your stomach, it's important to contact your doctor right away. Do not stop using any medications without talking to a doctor.
Co-administration of Amprenavir together with Clindacef 300mg Capsule can increase the effects of Clindacef 300mg Capsule.
How to manage the interaction:
Co-administration of Clindacef 300mg Capsule with Amprenavir can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have ongoing feelings of sickness, throwing up, having loose stools, or pain in your stomach, it's important to contact your doctor right away. Do not stop using any medications without talking to a doctor.
Drug-Food Interactions
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
Drug-Food Interactions
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Drug-Diseases Interactions
CLINDAMYCIN-300MGOther bacterial intestinal infections
Severe
CLINDAMYCIN-300MGDisorders related to short gestation and low birth weight, not elsewhere classified
Severe
Drug-Diseases Interactions
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CLINDAMYCIN-300MGOther bacterial intestinal infections
Severe
How does the disease interact with Clindacef 300mg Capsule:
Almost all antibacterial medications have been associated with reports of Clostridioides difficile-associated diarrhoea (CDAD), formerly known as pseudomembranous colitis. It can vary from mild diarrhoea to deadly colitis.
How to manage the interaction:
Clostridioides difficile-associated diarrhea (CDAD) ranging from mild diarrhoea to colitis has been reported during treatment with antibacterial agents. Therapy should be administered cautiously in patients with history of gastrointestinal disease, particularly colitis and pseudomembranous colitis. Appropriate fluid and electrolyte management, protein supplementation, and antibacterial treatment of C difficile is advised.
Almost all antibacterial medications have been associated with reports of Clostridioides difficile-associated diarrhoea (CDAD), formerly known as pseudomembranous colitis. It can vary from mild diarrhoea to deadly colitis.
How to manage the interaction:
Clostridioides difficile-associated diarrhea (CDAD) ranging from mild diarrhoea to colitis has been reported during treatment with antibacterial agents. Therapy should be administered cautiously in patients with history of gastrointestinal disease, particularly colitis and pseudomembranous colitis. Appropriate fluid and electrolyte management, protein supplementation, and antibacterial treatment of C difficile is advised.
CLINDAMYCIN-300MGDisorders related to short gestation and low birth weight, not elsewhere classified
Severe
How does the disease interact with Clindacef 300mg Capsule:
Benzyl alcohol is frequently used as a preservative in the formulation of multidose vials for parenteral medicines. Manufacturers of pharmaceuticals believe that using them in neonates, especially preterm and underweight newborns, is contraindicated. In low birth weight preterm newborns, the use of benzyl alcohol in bacteriostatic saline intravascular flush and endotracheal tube lavage solutions has been linked to mortality and serious respiratory and metabolic problems.
How to manage the interaction:
Parenteral medications containing benzyl alcohol as a preservative are contraindicated in neonates, particularly premature infants and infants of low birth weight.
Benzyl alcohol is frequently used as a preservative in the formulation of multidose vials for parenteral medicines. Manufacturers of pharmaceuticals believe that using them in neonates, especially preterm and underweight newborns, is contraindicated. In low birth weight preterm newborns, the use of benzyl alcohol in bacteriostatic saline intravascular flush and endotracheal tube lavage solutions has been linked to mortality and serious respiratory and metabolic problems.
How to manage the interaction:
Parenteral medications containing benzyl alcohol as a preservative are contraindicated in neonates, particularly premature infants and infants of low birth weight.
CLINDAMYCIN-300MGOther diseases of liver
Moderate
How does the disease interact with Clindacef 300mg Capsule:
The liver is the primary site of Clindacef 300mg Capsule metabolism. Patients with significantly impaired hepatic function may have a rise in the blood concentration of Clindacef 300mg Capsule and a prolongation of the half-life. Additionally, the drug's usage may result in abnormal liver enzyme levels and jaundice. Patients with liver problems should receive Clindacef 300mg Capsule therapy with caution. When given every 8 hours, dosage modifications might not be required. However, with high-dose therapy, serum concentrations should be observed, and during prolonged therapy, regular liver function tests should be carried out.
How to manage the interaction:
Clindacef 300mg Capsule is primarily metabolized by the liver. Therapy with Clindacef 300mg Capsule should be administered cautiously in patients with liver disease. Serum concentrations should be monitored during high-dose therapy, and periodic liver function tests should be performed during prolonged therapy.
The liver is the primary site of Clindacef 300mg Capsule metabolism. Patients with significantly impaired hepatic function may have a rise in the blood concentration of Clindacef 300mg Capsule and a prolongation of the half-life. Additionally, the drug's usage may result in abnormal liver enzyme levels and jaundice. Patients with liver problems should receive Clindacef 300mg Capsule therapy with caution. When given every 8 hours, dosage modifications might not be required. However, with high-dose therapy, serum concentrations should be observed, and during prolonged therapy, regular liver function tests should be carried out.
How to manage the interaction:
Clindacef 300mg Capsule is primarily metabolized by the liver. Therapy with Clindacef 300mg Capsule should be administered cautiously in patients with liver disease. Serum concentrations should be monitored during high-dose therapy, and periodic liver function tests should be performed during prolonged therapy.
CLINDAMYCIN-300MGOther disorders of kidney and ureter, not elsewhere classified
Moderate
How does the disease interact with Clindacef 300mg Capsule:
Clindacef 300mg Capsule is partially removed by the kidney. Clindacef 300mg Capsule should be used with caution in individuals with significantly impaired renal function. Dosage changes are probably to be required. Serum Clindacef 300mg Capsule concentrations should be monitored throughout high-dose therapy, and renal function tests should be conducted on a regular basis during extended medication.
How to manage the interaction:
Therapy with Clindacef 300mg Capsule should be administered cautiously in patients with severely impaired renal function. Serum Clindacef 300mg Capsule concentrations should be monitored during high-dose therapy, and periodic renal function tests should be performed during prolonged therapy.
Clindacef 300mg Capsule is partially removed by the kidney. Clindacef 300mg Capsule should be used with caution in individuals with significantly impaired renal function. Dosage changes are probably to be required. Serum Clindacef 300mg Capsule concentrations should be monitored throughout high-dose therapy, and renal function tests should be conducted on a regular basis during extended medication.
How to manage the interaction:
Therapy with Clindacef 300mg Capsule should be administered cautiously in patients with severely impaired renal function. Serum Clindacef 300mg Capsule concentrations should be monitored during high-dose therapy, and periodic renal function tests should be performed during prolonged therapy.
CLINDAMYCIN-300MGOther disorders of kidney and ureter, not elsewhere classified
Moderate
How does the disease interact with Clindacef 300mg Capsule:
Clindacef 300mg Capsule is partially removed by the kidney. Clindacef 300mg Capsule should be used with caution in individuals with significantly impaired renal function. Dosage changes are probably to be required. Serum Clindacef 300mg Capsule concentrations should be monitored throughout high-dose therapy, and renal function tests should be conducted on a regular basis during extended medication.
How to manage the interaction:
Therapy with Clindacef 300mg Capsule should be administered cautiously in patients with severely impaired renal function. Serum Clindacef 300mg Capsule concentrations should be monitored during high-dose therapy, and periodic renal function tests should be performed during prolonged therapy.
Clindacef 300mg Capsule is partially removed by the kidney. Clindacef 300mg Capsule should be used with caution in individuals with significantly impaired renal function. Dosage changes are probably to be required. Serum Clindacef 300mg Capsule concentrations should be monitored throughout high-dose therapy, and renal function tests should be conducted on a regular basis during extended medication.
How to manage the interaction:
Therapy with Clindacef 300mg Capsule should be administered cautiously in patients with severely impaired renal function. Serum Clindacef 300mg Capsule concentrations should be monitored during high-dose therapy, and periodic renal function tests should be performed during prolonged therapy.
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