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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Clome 50 Tablet

Clome 50 Tablet belongs to the group of medications called 'ovulation stimulants' used to treat infertility in women who are not ovulating (producing an egg) properly or have irregular or no menstrual cycle. The problem with ovulation is a common cause of infertility in women.

Clome 50 Tablet contains 'Clomifene Citrate' that works by stimulating the production of hormones responsible for the ovulation process.

Take Clome 50 Tablet as prescribed by your doctor. The common side-effects of Clome 50 Tablet are flushing (reddening of the skin, especially the face), headache, tiredness, dizziness, breast pain or tenderness, heavy periods, or bleeding between periods. Tell your doctor if any of these side effects persist or worsen.

Do not take Clome 50 Tablet if you are allergic to any of its ingredients, have liver disease, unexplained and unusual menstrual bleeding, have a type of cancer that gets worse by hormones, or have an ovarian cyst. Clome 50 Tablet is not recommended for pregnant women, children, adolescents, men, and post-menopausal women. Inform your doctor if you are breastfeeding as this medicine may affect the amount of breast milk produced.

Uses of Clome 50 Tablet

Female infertility

Directions for Use

Swallow Clome 50 Tablet as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Clome 50 Tablet belongs to the group of medications called 'ovulation stimulants' used for fertility enhancement in women experiencing infertility due to problems with ovulation (production and release of an egg from the ovary). It works by stimulating the hormones that are necessary for the ovulation process.

Storage

Store in a cool and dry place away from sunlight
Side effects of Clome 50 Tablet
  • Schedule a comprehensive medical evaluation with a specialized women's health expert.
  • Adhere to a personalized medication regimen to alleviate symptoms and promote ovarian health.
  • Embrace a holistic approach to wellness, incorporating nutritious eating habits and consistent physical activity.
  • Refrain from engaging in physically demanding tasks that may exacerbate discomfort.
  • Prioritize rejuvenation and relaxation, ensuring adequate sleep and downtime.
  • Explore complementary therapies, like acupuncture or botanical supplements, under the guidance of a qualified medical professional.
  • Inform your doctor about the hot flushes you're experiencing to assess whether the medication is causing the issue.
  • Your doctor may prescribe alternative medications or adjust your current dosage to minimize hot flushes.
  • To help alleviate symptoms, maintain a balanced diet rich in whole foods, fruits, vegetables, and omega-3 fatty acids.
  • To help reduce hot flashes, incorporate lifestyle changes such as regular exercise, stress management techniques, and adequate sleep.
  • Stay hydrated by drinking plenty of water and avoiding caffeine and alcohol.
  • Use fans or air conditioners to keep your environment cool and avoid triggers like spicy foods and hot beverages.
  • Consider incorporating foods and herbs that may help alleviate hot flushes, such as soy, flaxseeds, and black cohosh, into your diet.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Always wear loose-fitting clothes suitable for your activity during hot flashes.
  • Include a diet containing fruits like watermelon, grapes, bananas and green leafy vegetables.
  • Drink plenty of water and stay hydrated.
  • Stay calm and lower your anxiety by practising yoga or meditation.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Use hot or cold packs on your breasts to help alleviate discomfort.
  • Choose a supportive, well-fitting bra, preferably one that has been professionally fitted.
  • Practice relaxation techniques to manage stress and anxiety that may accompany severe breast pain.
  • Limit or avoid caffeine consumption.
  • Eat a low-fat diet and focus on foods rich in complex carbohydrates.
  • Rubbing evening primrose oil on your breasts may help balance fatty acids in the cells and reduce pain.
  • Keep track of when your breast pain occurs and any other symptoms to determine if the pain is regular or not.
  • Vitamin E supplements may help reduce pain for women who experience pain linked to their menstrual cycle.
  • Over-the-counter pain relievers like acetaminophen or ibuprofen can provide relief, but be sure to consult your doctor for the correct dosage, as prolonged use may cause side effects.
  • Get plenty of fresh air.
  • Take regular sips of a cold drink.
  • Take ginger containing foods like ginger tea and ginger biscuits.
  • Do not take heavy meals at a time, take small and frequent meals.

Drug Warnings

Do not consume Clome 50 Tablet if you are allergic or hypersensitive to Clomifene Citrate or any other ingredients of Clome 50 Tablet . Inform your doctor if you are having an early menopause, diagnosed as infertile, menstrual periods were stopped due to being underweight, previously diagnosed with fits or seizures (fits), uterine fibroids (non-cancerous tumours in the womb), polycystic ovaries (presence of small cysts on the enlarged ovaries), swollen ovaries, or hypertriglyceridemia (increased fat levels in the body) or a family history of hypertriglyceridemia.

Drug-Drug Interactions

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clomipheneOspemifene
Critical
clomipheneBexarotene
Severe

Drug-Drug Interactions

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clomipheneOspemifene
Critical
How does the drug interact with Clome 50 Tablet:
Co-administration of Clomifene with Ospemifene can increase the seriousness of side effects.

How to manage the interaction:
Taking Clome 50 Tablet with Ospemifene is not recommended, please consult a doctor before taking it.
clomipheneBexarotene
Severe
How does the drug interact with Clome 50 Tablet:
Co-administration of Clome 50 Tablet with Bexarotene may increase the risk of pancreatitis, or inflammation of the pancreas.

How to manage the interaction:
Although there is an interaction, Clome 50 Tablet can be taken with Bexarotene if prescribed by the doctor. Consult the prescriber if you experience symptoms of pancreatitis such as persistent nausea, vomiting, abdominal tenderness, and upper abdominal pain, especially that which is made worse after eating or radiates to the back. Do not discontinue the medication without consulting a doctor.
clomipheneFluoroestradiol (18f)
Severe
How does the drug interact with Clome 50 Tablet:
Co-administration of Fluoroestradiol F 18 together with Clome 50 Tablet may reduce the action of Fluoroestradiol F 18.

How to manage the interaction:
Taking Clome 50 Tablet with Fluoroestradiol (18f) together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Consume a healthy diet rich in fibre and proteins and low in carbohydrates and fats. 
  • Avoid processed or high-sugar foods. 
  • Stay active and shed excess weight if you are overweight or obese. Do not perform intense exercises as they may negatively impact your reproductive health. Increase the intensity of exercise gradually.
  • Being underweight may also reduce your chances of getting pregnant. So, prepare a diet chart that can help you gain weight healthily. 
  • Avoid stress as it may decrease your chances of getting pregnant. Try relaxation techniques and receive support and counselling if necessary. 
  • Limit alcohol and caffeine intake.
  • Quit smoking.

Habit Forming

No

Therapeutic Class

GYNECOLOGY RELATED DRUGS

Author Details

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Drug-Diseases Interactions

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CLOMIFENE CITRATE-50MGOther abnormal uterine and vaginal bleeding
Severe
CLOMIFENE CITRATE-50MGHepatic failure, not elsewhere classified
Severe

Drug-Diseases Interactions

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CLOMIFENE CITRATE-50MGOther abnormal uterine and vaginal bleeding
Severe
How does the disease interact with Clome 50 Tablet:
Abnormal uterine bleeding: In patients who are not diagnosed with abnormal genital bleeding, Clome 50 Tablet is contraindicated. Evaluate the patients for the presence of neoplastic lesions.

How to manage the interaction:
The use of Clome 50 Tablet is contraindicated in patients with undiagnosed, abnormal genital bleeding.
CLOMIFENE CITRATE-50MGHepatic failure, not elsewhere classified
Severe
How does the disease interact with Clome 50 Tablet:
Hepatic dysfunction: Clome 50 Tablet is contraindicated for patients who have liver failure or a past history of hepatic dysfunction. The Clome 50 Tablet is primarily metabolized in the liver and enters into enterohepatic circulation. Thus, there will be increase in serum concentration and half-life of Clome 50 Tablet.

How to manage the interaction:
The use of Clome 50 Tablet is contraindicated in patients with liver disease or history of hepatic dysfunction.
CLOMIFENE CITRATE-50MGDisorders of endocrine glands in diseases classified elsewhere
Severe
How does the disease interact with Clome 50 Tablet:
Pituitary activity: Clome 50 Tablet is contraindicated for patients who have uncontrolled thyroid or adrenal dysfunction, or who have an organic intracranial lesion such as a pituitary tumour. Clome 50 Tablet interacts with oestrogen receptors in several tissues, including the pituitary, causing a rise in pituitary gonadotropin secretion.

How to manage the interaction:
Clome 50 Tablet is contraindicated in patients with uncontrolled thyroid, adrenal dysfunction or pituitary tumour.
CLOMIFENE CITRATE-50MGOther disorders of adrenal gland
Severe
How does the disease interact with Clome 50 Tablet:
Uncontrolled adrenal dysfunction : Clome 50 Tablet is contraindicated in patients with uncontrolled adrenal function. Adrenal dysfunction can make pregnancy difficult. Clome 50 Tablet therapy may cause changes in steroid production and/or fluid balance.

How to manage the interaction:
The use of Clome 50 Tablet is contraindicated in patients with uncontrolled adrenal function.
CLOMIFENE CITRATE-50MGDisorders of lipoprotein metabolism and other lipidaemias
Moderate
How does the disease interact with Clome 50 Tablet:
Hyperlipidemia: Some patients who are on Clome 50 Tablet therapy have reported hypertriglyceridemia. Preexisting hyperlipidemia or a family history of hyperlipidemia, Higher doses of Clome 50 Tablet for a long period are related to an increased risk of hypertriglyceridemia. In this conditions, Monitor plasma triglycerides regular basis and also at base line before initiating the therapy with Clome 50 Tablet.

How to manage the interaction:
Hypertriglyceridemia may occur during Clome 50 Tablet therapy, especially in patients with a family history of hyperlipidemia and use of higher than the recommended dose and/or longer duration of treatment. Periodic monitoring of plasma triglycerides is recommended in patients with preexisting or family history of hyperlipidemia. Pretreatment screening of triglyceride levels is advised in patients initiating Clome 50 Tablet therapy.

FAQs

Clome 50 Tablet works by stimulating the production of necessary hormones for ovulation. Thus, it enhances fertility by inducing ovulation in women with fertility problems.

In most cases, women ovulate within 7 to 10 days after taking this medicine. However, ask your doctor if you have any questions regarding the benefits of Clome 50 Tablet .

Clome 50 Tablet can only enhance your chances of fertility. Not getting pregnant after taking this medicine may be due to low dosage, other underlying causes of infertility, or any comorbid conditions that interfere with Clome 50 Tablet action. Consult your doctor to know the exact reason.

Most women ovulate 7 to 10 days following their last Clome 50 Tablet dose. It would help if you had intercourse every day or every other day from Day 11 through Day 21 of your cycle.

Clome 50 Tablet is a fertility medicine used to treat a variety of infertility difficulties. It works by increasing the development of eggs inside the ovaries' follicles. This can also help develop more mature follicles, resulting in the release of numerous eggs during ovulation, increasing your chances of conceiving a twin, triplet, or more.

Clome 50 Tablet is not a cure for infertility. It can only enhance your chance of getting pregnant by inducing ovulation.

Drug-Drug Interactions Checker List

  • BEXAROTENE

Special Advise

Clome 50 Tablet may cause multiple pregnancies (pregnant with more than one child at the same time) or ectopic pregnancy (growing foetus outside the womb). These conditions may also occur if you are not taking this medicine. However, discuss with your doctor the possible risks before taking Clome 50 Tablet .

Disease/Condition Glossary

Female Infertility: A woman is said to have fertility problems when she cannot become pregnant within a year of trying. If a woman gets pregnant but experiences miscarriages or stillbirths, it is also included in infertility. The most common cause of infertility is the problem with ovulation or damage to the uterus.

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