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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Non returnable*
COD available

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Composition :

CLONIDINE-150MCG

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Cloneon Injection 1 ml

Cloneon Injection 1 ml belongs to a class of medicines called antihypertensives used to treat hypertension (high blood pressure). Besides this, Cloneon Injection 1 ml is also used alone or in combination with opiate medicines for the treatment of severe pain in cancer patients which is not sufficiently relieved by opioid analgesics alone. 
 
Cloneon Injection 1 ml relaxes and widens the blood vessels making it easier for the heart to pump blood to all parts of the body. This helps in lowering the blood pressure and the risk of having a heart attack or stroke. Also, Cloneon Injection 1 ml prevents the transmission of pain signals to the brain, thereby providing relief from pain.
 
In some cases, Cloneon Injection 1 ml may cause dry mouth, headache, dizziness, nausea, postural hypotension and low blood pressure. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Cloneon Injection 1 ml is not recommended for obstetrical (related to childbirth), post-partum, or peri-operative pain management. Consult your doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding while taking Cloneon Injection 1 ml. Cloneon Injection 1 ml may cause dizziness, so drive only if you are alert. Keep your doctor informed about your health condition and medications to rule out any interactions/side effects.

Uses of Cloneon Injection 1 ml

Hypertension (high blood pressure), Pain relief

Directions for Use

Cloneon Injection 1 ml will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Cloneon Injection 1 ml is used to treat hypertension (high blood pressure). Cloneon Injection 1 ml relaxes and widens the blood vessels making it easier for the heart to pump blood to all parts of the body. This helps in lowering the blood pressure and the risk of having a heart attack or stroke. Cloneon Injection 1 ml is also used alone or in combination with opiate medicines for the treatment of severe pain in cancer patients which is not sufficiently relieved by opioid analgesics alone. Cloneon Injection 1 ml prevents the transmission of pain signals to the brain, thereby providing relief from pain.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Cloneon Injection 1 ml if you are allergic to any of its contents. Inform your doctor if you have/had bleeding problems, circulation problems, stroke, depression, diabetes, nervous problems, constipation, phaeochromocytoma (tumour of adrenal glands), heart, kidney or liver problems. Consult your doctor if you are pregnant or breastfeeding. Cloneon Injection 1 ml is not recommended for children as safety and effectiveness have not been established. Cloneon Injection 1 ml may cause dizziness, so avoid driving or operating machinery unless you are alert.

Drug-Drug Interactions

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ClonidineAmoxapine
Severe
ClonidineMetoprolol Tartrate
Severe

Drug-Drug Interactions

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ClonidineAmoxapine
Severe
How does the drug interact with Cloneon Injection 1 ml:
Co-administration of Cloneon Injection 1 ml and Amoxapine may increase the risk and severity of increased side effects.

How to manage the interaction:
Although there is a possible interaction between Cloneon Injection 1 ml and Amoxapine, you can take these medicines together if prescribed by a doctor. However, contact a doctor if you experience sweating, nausea, vomiting, dizziness, flushing, stiff neck, headache, or heart palpitations. Do not discontinue the medication without consulting a doctor.
ClonidineMetoprolol Tartrate
Severe
How does the drug interact with Cloneon Injection 1 ml:
Co-administration of Cloneon Injection 1 ml and Metoprolol Tartrate together may lower blood pressure and slower heart rate.

How to manage the interaction:
Although there is a possible interaction between Cloneon Injection 1 ml and Metoprolol Tartrate, you can take these medicines together if prescribed by a doctor. However, if you experience headaches, slow heartbeat, or dizziness, contact a doctor. You are advised to maintain your blood pressure. Do not discontinue the medication without consulting a doctor.
ClonidineSodium oxybate
Severe
How does the drug interact with Cloneon Injection 1 ml:
Co-administration of Cloneon Injection 1 ml can enhance the sedative effects of Sodium oxybate on the central nervous system.

How to manage the interaction:
Co-administration of Cloneon Injection 1 ml with Sodium oxybate can possibly result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on your health and be aware of any changes. If you notice any of these signs - feeling tired, dizzy, lightheaded, confused, sad, having low blood pressure, or difficulty breathing - make sure to contact your doctor right away. Do not stop using any medications without talking to a doctor.
ClonidineImipramine
Severe
How does the drug interact with Cloneon Injection 1 ml:
Co-administration of Cloneon Injection 1 ml and Imipramine may increase the risk and severity of increased blood pressure.

How to manage the interaction:
Although there is a possible interaction between Cloneon Injection 1 ml and Imipramine, you can take these medicines together if prescribed by a doctor. However, if you experience sweating, nausea, vomiting, dizziness, flushing, stiff neck, headache, or heart palpitations, contact a doctor. Do not discontinue the medication without consulting a doctor.
ClonidineNebivolol
Severe
How does the drug interact with Cloneon Injection 1 ml:
Co-administration of Cloneon Injection 1 ml and nebivolol together may lower blood pressure and slow your heart rate.

How to manage the interaction:
Taking Cloneon Injection 1 ml and nebivolol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClonidineMetoprolol
Severe
How does the drug interact with Cloneon Injection 1 ml:
Co-administration of Cloneon Injection 1 ml and Metoprolol may lower blood pressure and slow the heart rate.

How to manage the interaction:
Although there is a possible interaction between Cloneon Injection 1 ml and Metoprolol, you can take these medicines together if prescribed by your doctor. However, if you experience headaches, slow heartbeat, dizziness, or feeling like you might pass out, contact your doctor. Do not stop using any medications without first talking to your doctor.
ClonidineCarteolol
Severe
How does the drug interact with Cloneon Injection 1 ml:
Co-administration of Cloneon Injection 1 ml and Carteolol may lower blood pressure and slower heart rate.

How to manage the interaction:
Although there is a possible interaction between Cloneon Injection 1 ml and Carteolol, you can take these medicines together if prescribed by a doctor. However, if you experience headaches, slow heartbeat, dizziness, or feeling like you might pass out, contact a doctor. Do not discontinue the medication without consulting a doctor.
ClonidineAmitriptyline
Severe
How does the drug interact with Cloneon Injection 1 ml:
Co-administration of Cloneon Injection 1 ml and Amitriptyline may increase the risk and severity of increased side effects.

How to manage the interaction:
Although there is a possible interaction between Cloneon Injection 1 ml and Amitriptyline, you can take these medicines together if prescribed by a doctor. However, contact a doctor if you experience sweating, nausea, vomiting, dizziness, flushing, stiff neck, headache, or heart palpitations. Do not stop any medication without doctor's advise.
ClonidineNadolol
Severe
How does the drug interact with Cloneon Injection 1 ml:
Co-administration of Cloneon Injection 1 ml and Nadolol may lower blood pressure and slower heart rate.

How to manage the interaction:
Although there is a possible interaction between Cloneon Injection 1 ml and Nadolol, you can take these medicines together if prescribed by your doctor. However, if you experience headaches, slow heartbeat, dizziness, or feeling like you might pass out, contact your doctor. Do not discontinue the medication without consulting a doctor.
ClonidineNortriptyline
Severe
How does the drug interact with Cloneon Injection 1 ml:
Co-administration of Cloneon Injection 1 ml and Nortriptyline may increase the risk and severity of increased blood pressure.

How to manage the interaction:
Although there is a possible interaction between Cloneon Injection 1 ml and Nortriptyline, you can take these medicines together if prescribed by your doctor. However, if you experience sweating, nausea, vomiting, dizziness, flushing, stiff neck, headache or heart palpitations, contact a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • You are advised to consume low salt and low-fat diet while taking Cloneon Injection 1 ml. 
  • Regular exercise is also recommended to complement treatment with Cloneon Injection 1 ml.
  • Eat a diet rich in whole grains, vegetables, and fruits.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight with proper diet and exercise.
  • Manage stress with meditation, yoga, and massage.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Author Details

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Drug-Diseases Interactions

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CLONIDINE-150MCGAbnormalities of heart beat
Moderate
CLONIDINE-150MCGDepressive episode
Moderate

Drug-Diseases Interactions

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CLONIDINE-150MCGAbnormalities of heart beat
Moderate
How does the disease interact with Cloneon Injection 1 ml:
Alpha-2 adrenoreceptor agonists in the central nervous system decrease sympathetic outflow. Atrioventricular block and sinus bradycardia may develop or worsen as a result of the reduced heart rate. Patients with conduction problems such sinus node dysfunction or AV nodal illness should use caution while receiving therapy with central alpha-2 adrenoreceptor agonists.

How to manage the interaction:
Cloneon Injection 1 ml should be used with caution in patients with heart problems.
CLONIDINE-150MCGDepressive episode
Moderate
How does the disease interact with Cloneon Injection 1 ml:
In patients who have a history of depression, central alpha-2 adrenoreceptor agonists should be administered with caution since they can occasionally result in mental depression.

How to manage the interaction:
Cloneon Injection 1 ml should be used with caution in patients with a history of depression.
CLONIDINE-150MCGHypotension
Moderate
How does the disease interact with Cloneon Injection 1 ml:
As a result of decreased sympathetic outflow from the central nervous system caused by central alpha-2 adrenoreceptor agonists, blood pressure, peripheral and renovascular resistance, and heart rate all decreased. Patients who have hypotension or illnesses that could be made worse by low blood pressure and perfusion, such as coronary insufficiency, peripheral vascular disease (like Raynaud's syndrome), cerebrovascular disease, or a recent myocardial infarction, should use these medications with caution.

How to manage the interaction:
Cloneon Injection 1 ml should be used with caution in patients with hypotension (low blood pressure) or conditions that may worsen by decreased blood pressure, such as coronary insufficiency (inadequate blood circulation through coronary arteries), peripheral vascular disease (e.g., Raynaud's syndrome), cerebrovascular disease (conditions that affect blood flow to your brain), or recent myocardial infarction (heart attack).
CLONIDINE-150MCGHypotension
Moderate
How does the disease interact with Cloneon Injection 1 ml:
As a result of decreased sympathetic outflow from the central nervous system caused by central alpha-2 adrenoreceptor agonists, blood pressure, peripheral and renovascular resistance, and heart rate all decreased. Patients who have hypotension or illnesses that could be made worse by low blood pressure and perfusion, such as coronary insufficiency, peripheral vascular disease (like Raynaud's syndrome), cerebrovascular disease, or a recent myocardial infarction, should use these medications with caution.

How to manage the interaction:
Cloneon Injection 1 ml should be used with caution in patients with hypotension (low blood pressure) or conditions that may worsen by decreased blood pressure, such as coronary insufficiency (inadequate blood circulation through coronary arteries), peripheral vascular disease (e.g., Raynaud's syndrome), cerebrovascular disease (conditions that affect blood flow to your brain), or recent myocardial infarction (heart attack).
CLONIDINE-150MCGHypotension
Moderate
How does the disease interact with Cloneon Injection 1 ml:
As a result of decreased sympathetic outflow from the central nervous system caused by central alpha-2 adrenoreceptor agonists, blood pressure, peripheral and renovascular resistance, and heart rate all decreased. Patients who have hypotension or illnesses that could be made worse by low blood pressure and perfusion, such as coronary insufficiency, peripheral vascular disease (like Raynaud's syndrome), cerebrovascular disease, or a recent myocardial infarction, should use these medications with caution.

How to manage the interaction:
Cloneon Injection 1 ml should be used with caution in patients with hypotension (low blood pressure) or conditions that may worsen by decreased blood pressure, such as coronary insufficiency (inadequate blood circulation through coronary arteries), peripheral vascular disease (e.g., Raynaud's syndrome), cerebrovascular disease (conditions that affect blood flow to your brain), or recent myocardial infarction (heart attack).
CLONIDINE-150MCGOther disorders of kidney and ureter, not elsewhere classified
Moderate
How does the disease interact with Cloneon Injection 1 ml:
The kidney is principally responsible for the unaltered elimination of Cloneon Injection 1 ml. Patients may benefit from a lower initial dose since the serum concentrations and half-life of Cloneon Injection 1 ml may be enhanced in those with impaired renal function. The degree of renal impairment should be taken into consideration while modifying the dosage. There is no need to provide more Cloneon Injection 1 ml after dialysis since only a little quantity of Cloneon Injection 1 ml is eliminated during regular hemodialysis.

How to manage the interaction:
Dose adjustments may be required based on the degree of kidney impairment. Therefore, inform your doctor if you have any kidney problems before taking Cloneon Injection 1 ml.
CLONIDINE-150MCGOther disorders of kidney and ureter, not elsewhere classified
Moderate
How does the disease interact with Cloneon Injection 1 ml:
The kidney is principally responsible for the unaltered elimination of Cloneon Injection 1 ml. Patients may benefit from a lower initial dose since the serum concentrations and half-life of Cloneon Injection 1 ml may be enhanced in those with impaired renal function. The degree of renal impairment should be taken into consideration while modifying the dosage. There is no need to provide more Cloneon Injection 1 ml after dialysis since only a little quantity of Cloneon Injection 1 ml is eliminated during regular hemodialysis.

How to manage the interaction:
Dose adjustments may be required based on the degree of kidney impairment. Therefore, inform your doctor if you have any kidney problems before taking Cloneon Injection 1 ml.

FAQs

Cloneon Injection 1 ml relaxes and widens the blood vessels making it easier for the heart to pump blood to all parts of the body. This helps in lowering the blood pressure and the risk of having a heart attack or stroke. Cloneon Injection 1 ml prevents the transmission of pain signals to the brain, thereby provides relief from pain.

Dry mouth could be a side effect of Cloneon Injection 1 ml. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.

Postural hypotension could be a side-effect of Cloneon Injection 1 ml. Postural hypotension is a sudden lowering in blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead lie down and get up slowly only when you feel better.

Sudden cessation of treatment with Cloneon Injection 1 ml may cause symptoms such as agitation, headache, nervousness, tremor, and rise in blood pressure. Your doctor will reduce the dose gradually to avoid withdrawal symptoms.

Please consult your doctor before taking other medicines with Cloneon Injection 1 ml. Particularly, inform your doctor if you are taking medicines used to treat high blood pressure, heart problems, depression, mood swings, or pain relievers.

Drug-Drug Interactions Checker List

  • DIGITALIS
  • FLUPHENAZINE

Special Advise

  • Regularly monitor blood pressure levels to prevent hypotension (low blood pressure).
  • Get up slowly while rising from lying or sitting position as Cloneon Injection 1 ml may cause dizziness.
  • Your doctor may advise you to get regular kidney function tests and potassium levels tested whilst on treatment with Cloneon Injection 1 ml. 

Disease/Condition Glossary

High blood pressure (hypertension): It is a condition in which the blood exerts increased pressure on the walls of blood vessels leading to hypertension. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack. Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. Symptoms of high blood pressure include headache, dizziness, nose bleed, changes in vision, chest pain, weakness and dyspnoea (shortness of breath). However, most of the time, the signs and symptoms of hypertension are none.

Pain: It is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp; it might be constant or may come and go. The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures, arthritis, stomach ache, and certain medical conditions.

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