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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
COD available

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Manufacturer/Marketer :

Knoll Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Clopinol-AT Tablet

Clopinol-AT Tablet is a combination drug composed of a blood-thinning agent and cholesterol-lowering agent primarily used to prevent heart attack and stroke in the future. It lowers the raised level of cholesterol and fats (triglycerides) in our bodies. A heart attack occurs when your coronary arteries (blood vessels supplying blood and oxygen to the heart) becomes blocked due to the build-up of fats (plaque), including cholesterol. These plaques narrow the arteries, leading to atherosclerosis and coronary artery disease, mainly for most heart attacks.

Clopinol-AT Tablet is composed of two medicines, namely: Atorvastatin and Clopidogrel. Atorvastatin is a lipid-lowering medication which blocks the enzyme required to make cholesterol in the body. As a result, it lowers the bad cholesterol (low-density lipoproteins or LDL) and triglycerides (TG) and increases the levels of good cholesterol (high-density lipoproteins or HDL). Clopidogrel is a blood thinner (anticoagulant) that collectively prevents a clot in the blood vessels. Together Clopinol-AT Tablet reduces the increased levels of bad cholesterol (low-density lipoprotein and triglycerides) and prevents blood clots, thereby reducing the risk of heart attack, stroke and heart-related chest pain (angina).

You can take Clopinol-AT Tablet with food or without food. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. Your doctor will advise you on how often you take this medicine based on your medical condition. You may sometimes experience headaches, ankle swelling (oedema), slow heart rate, and nausea. Clopinol-AT Tablet is known to cause dizziness, so driving should be avoided. Most of these side effects of Clopinol-AT Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking a Clopinol-AT Tablet of your own. Suddenly stopping using Clopinol-AT Tablet may worsen your condition and increase your risk of a future heart attack. Let your doctor know if you are sensitive to atorvastatin or clopidogrel or have any active liver disease (liver enzyme abnormalities), active bleeding issues (like peptic ulcer, brain haemorrhage), or muscle problem (myopathy, rhabdomyolysis). The patient should inform the doctor they are taking Clopinol-AT Tablet before any surgery or any new medicine is taken. Atorvastatin, present in Clopinol-AT Tablet is a pregnancy category X drug, so it should not be given to pregnant women. It may cause harm to the foetus if administered to pregnant or breastfeeding women.

Uses of Clopinol-AT Tablet

Hyperlipidemia (Increased cholesterol), Prevention of heart attack, Prevention of stroke.

Directions for Use

Swallow the tablet as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Atorvastatin is a lipid-lowering medication that blocks the enzyme required to make cholesterol in the body. As a result, it lowers the bad cholesterol (low-density lipoproteins or LDL) and triglycerides (TG) and increases the levels of good cholesterol (high-density lipoproteins or HDL). Clopidogrel is a blood thinner (anticoagulant) that collectively prevents clot formation in the blood vessels. Together Clopinol-AT Tablet reduces the increased levels of bad cholesterol (low-density lipoprotein and triglycerides) and prevents blood clots, thereby reducing the risk of heart attack, stroke and heart-related chest pain (angina).

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Tell your doctor if you are sensitive to Atorvastatin or clopidogrel, have any active liver disease, active bleeding issues (like peptic ulcer, brain haemorrhage), are pregnant or planning to become pregnant or breastfeeding. The patient should inform the doctor that they are taking Clopinol-AT Tablet before any surgery is scheduled or any new medicine is taken. Atorvastatin present in Clopinol-AT Tablet is a pregnancy category X drug, so it is contraindicated in pregnant women. As it may cause harm to the foetus if administered to pregnant women. The risk of muscle disease might increase if Clopinol-AT Tablet is taken with an antibiotic (clarithromycin), anti-HIV drugs (ritonavir, lopinavir, darunavir, atazanavir, indinavir) and antifungal (itraconazole). Coadministration with anticoagulants like warfarin may cause gastric bleeding and other bleeding problems. So, if you are using any blood-thinning agents, let your doctor know about this. Clopinol-AT Tablet contains Atorvastatin which can cause muscle problems like myopathy and rhabdomyolysis. Patients with active liver disease should use the Clopinol-AT Tablet with caution. The safety and effectiveness of Clopinol-AT Tablet have not been established, so its use should be avoided in paediatric patients or children younger than ten years of age. Discontinuation of Clopinol-AT Tablet may lead to cardiovascular events like heart attack, stroke and angina (heart-related chest pain). Hence, you should consult a doctor before stopping the dose of Clopinol-AT Tablet .

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Clopinol-AT Tablet:
When Selexipag and Clopinol-AT Tablet are taken together, the body's ability to break down Selexipag may be reduced.

How to manage the interaction:
Taking Clopinol-AT Tablet with Selexipag is not recommended, please consult your doctor before taking it. They can be taken if prescribed by your doctor.
How does the drug interact with Clopinol-AT Tablet:
Taking Clopinol-AT Tablet together with mifepristone increases the risk of vaginal bleeding in women.

How to manage the interaction:
Although taking Clopinol-AT Tablet with mifepristone is not recommended, that would certainly result in interaction, it can be taken if a doctor prescribes it. If you experience prolonged and heavy bleeding, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Clopinol-AT Tablet:
Taking Clopinol-AT Tablet with Posaconazole can increase the blood levels of Clopinol-AT Tablet. This can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between posaconazole with Clopinol-AT Tablet, they can be taken together if advised by your doctor. However, contact the doctor if you experience unexplained muscle pain, weakness, fever, chills, joint pain or swelling, unusual bleeding, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark coloured urine, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Clopinol-AT Tablet:
Taking loperamide with Clopinol-AT Tablet may significantly increase the blood levels of loperamide. This can lead to serious and complications such as irregular heart rhythm.

How to manage the interaction:
Although talking Clopinol-AT Tablet with loperamide may result in an interaction, it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, or shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Clopinol-AT Tablet:
Taking fluvoxamine can lower the levels of Clopinol-AT Tablet in the blood, which can result in a decreased effectiveness of Clopinol-AT Tablet.

How to manage the interaction:
Taking Clopinol-AT Tablet and Fluvoxamine together possibly has an interaction, but you can take these medications together if your doctor has advised it. However, if you experience shortness of breath, dizziness, loss of balance, or trouble walking, consult your doctor immediately. Do not discontinue any medication without consulting your doctor.
How does the drug interact with Clopinol-AT Tablet:
Taking Clopinol-AT Tablet with Ibrutinib can increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Clopinol-AT Tablet and Ibrutinib, they can be taken together if prescribed by a doctor. However, if you experience any feeling dizzy or lightheaded, red or black, sticky stools, severe headache, or weakness, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Clopinol-AT Tablet:
Taking Clopinol-AT Tablet with Tirofiban can make the antiplatelet effects of Tirofiban stronger.

How to manage the interaction:
There may be a possibility of interaction between Tirofiban and Clopinol-AT Tablet, but it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Clopinol-AT Tablet:
Coadministration of Clopinol-AT Tablet with modafinil can reduce the effectiveness of Clopinol-AT Tablet.

How to manage the interaction:
Although taking Clopinol-AT Tablet with Modafinil may possibly result in interaction, but it can be taken together if prescribed by a doctor. Do not stop using any medications without talking to your doctor.
How does the drug interact with Clopinol-AT Tablet:
Clopinol-AT Tablet increases the blood levels of Repaglinide, which results in increased effectiveness of Repaglinide. When these medicines are taken together, you may experience low blood sugar (hypoglycemia).

How to manage the interaction:
Although taking Clopinol-AT Tablet with Repaglinide may result in interaction, it can be taken if prescribed by a doctor. However, if you experience any signs of hypoglycemia (low blood sugar), consult your doctor immediately. Common symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, weakness, tremor, nausea, hunger, sweating, and palpitation. It is advised to monitor your blood sugar levels if you experience the above symptoms. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Clopinol-AT Tablet:
Taking cabozantinib together with Clopinol-AT Tablet may increase the risk of bleeding.

How to manage the interaction:
Taking Clopinol-AT Tablet with Cabozantinib together can result in an interaction, but it can be taken if your doctor has advised it. Contact your doctor immediately if you notice symptoms like bleeding, bruising, dizziness, or black stools. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Low cholesterol diet along with a regular exercise regime is found to complement treatment with Clopinol-AT Tablet effectively.
  • Stick to a freshly prepared home-cooked meal and avoid processed, packed foods that contain hidden sugar and extra calories.
  • Try to replace most of your saturated fats with unsaturated fats to reduce total cholesterol and LDL cholesterol (bad cholesterol) quickly.
  • Foods like avocados, olive oil, fatty fish and nuts contain many heart-healthy unsaturated fats, so eating them regularly is beneficial.
  • Include a diet enriched in fats like fish oils, polyunsaturated oils, and omega-3 fatty acids, which are good for heart health.
  • Quit smoking and avoid excessive intake of alcohol.

Habit Forming

No

Therapeutic Class

CARDIOVASCULAR AGENTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Yes, Clopinol-AT Tablet contains clopidogrel which prevents blood clotting. It works by preventing platelets (a type of blood cell) from sticking together and forming clots which in turn prevents the risk of heart attack and stroke.

Yes, taking Clopinol-AT Tablet can increase the risk of bleeding as it contains aspirin and clopidogrel which belongs to a class of blood-thinning agents. So, please be very cautious while shaving, cutting fingernails or toenails, or using sharp objects to avoid any bleeding. Let your doctor know before going any surgical procedure, that you are taking Clopinol-AT Tablet .

No. Clopinol-AT Tablet contains Atorvastatin which is pregnancy category X medicine and can cause harm to both pregnant mother and unborn baby. Even if you are planning for pregnancy tell your doctor that you are using Clopinol-AT Tablet .

Yes, prolonged use of Clopinol-AT Tablet may cause muscle diseases like myopathy and rhabdomyolysis. So if you feel any musculoskeletal pain after taking Clopinol-AT Tablet consult your doctor about this issue.

Do not drink grapefruit juice while taking Clopinol-AT Tablet . Grapefruit juice may increase the blood-thinning effect of your medicine.

Drinking alcohol with Clopinol-AT Tablet may damage your liver and increase liver enzymes like transaminase. So, Clopinol-AT Tablet should be used with caution who consume alcohol and/or have past history of liver disease.

If you accidentally take an overdose of Clopinol-AT Tablet you may have liver problems (increased secretion of liver enzymes) and bleeding complications. If problems persist you should immediately go to the nearby clinic or hospital.

You should have a total lipid profile (TG, HDL, LDL, VLDL, TC) and Blood coagulation tests like Complete blood count (CBC), Factor V assay, Fibrinogen Test, Prothrombin time (PT or PT-INR), Platelet count, Thrombin time and Bleeding time to analyze your blood clot timing and cholesterol level.

Drug-Drug Interactions Checker List

  • CLARITHROMYCIN
  • RITONAVIR
  • LOPINAVIR
  • DARUNAVIR
  • ATAZANAVIR
  • INDINAVIR
  • ITRACONAZOLE
  • WARFARIN
  • COUMADIN
  • HEPARIN
  • COLCHICINE
  • DIGOXIN
  • CYCLOSPORINE

Special Advise

  • If you have a high cholesterol level, try to have a lipid profile test (LFT) every 6 months.

 

Disease/Condition Glossary

Atherosclerosis: Atherosclerosis occurs when fats, cholesterol, and other substances known as plaque deposit on your artery walls that restrict blood flow. This plaque formation triggers blood clots, narrows the arteries' size, and hardens them. This, in turn, can lead to various heart complications like atherosclerosis, heart attack, heart-related chest pain (angina), and stroke. However, it can also affect the body's arteries apart from the heart.

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