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Whats That
About Closol-CZ Cream
Closol-CZ Cream is a dermatological combination medication used to reduce swelling, itching, and redness caused due to certain fungal skin infections. Fungal infection is a skin disease in which a fungus attacks the skin tissue and causes infection. Fungal infections may be contagious (spread from one person to another).
Closol-CZ Cream contains Clobetasol (corticosteroid), Miconazole (antifungal), and Zinc sulfate (antiseptic and astringent). Clobetasol belongs to the class of corticosteroids that works by acting inside skin cells and inhibiting the release of certain chemical messengers in the body that cause redness, itching, and swelling. When the skin reacts to any allergens, such chemicals are released normally. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Miconazole works by causing holes in the fungal cell membranes and kills fungi. Zinc sulfate has anti-inflammatory properties and relieves the redness, irritation, and scars caused by acne.
Closol-CZ Cream is only for external use. Take a small amount of Closol-CZ Cream on the finger and apply it as a thin layer on the clean and dry affected area. Avoid contact of Closol-CZ Cream with nose, ears, mouth, or eyes. In case Closol-CZ Cream comes in contact with these areas accidentally, rinse with water thoroughly. Some people may experience dry skin, itching, irritation, redness, or burning sensation at the application site. Most of these side effects of Closol-CZ Cream do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are known to be allergic to Closol-CZ Cream or any other medicines, please tell your doctor. If you are pregnant or a nursing mother, it is advised to consult a doctor before using Closol-CZ Cream. Do not use Closol-CZ Cream in more than prescribed doses or for prolonged periods as it may cause adverse effects. Do not wrap or cover the treated area with bandages unless your doctor advises. Avoid using Closol-CZ Cream for more than five days in children and on the face. Do not apply Closol-CZ Cream to broken skin or cuts. Do not swallow Closol-CZ Cream. In case of accidental swallowing, contact a nearby poison control centre or consult a doctor immediately. Avoid smoking or going near naked flames, as the Closol-CZ Cream catches fire and burns easily. If you have glaucoma, cataracts, diabetes, psoriasis, adrenal gland, or liver problems, inform your doctor before taking Closol-CZ Cream.
Uses of Closol-CZ Cream
Directions for Use
Medicinal Benefits
Closol-CZ Cream is a combination of three drugs: Clobetasol, Miconazole, and Zinc sulfate. Closol-CZ Cream is used to reduce swelling, itching, and redness caused due to fungal skin infections. Clobetasol is a corticosteroid that acts inside skin cells and inhibits the release of certain chemical messengers in the body that cause redness, itching, and swelling. When the skin reacts to any allergens, such chemicals are released normally. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Miconazole is an antifungal that causes holes in the fungal cell membranes and kills fungi. Zinc sulfate is antiseptic and astringent that heals skin wounds and ulcers. It also has anti-inflammatory properties and relieves the redness, irritation, and scars caused by acne. It has peeling and antioxidant effects and cleanses the skin, tightens pores, and reduces oil production.
Storage
Side Effects of Closol-CZ Cream
Drug Warnings
Avoid contact of Closol-CZ Cream with nose, mouth, or eyes as it may irritate. In case Closol-CZ Cream comes in contact with these areas accidentally, rinse with water thoroughly. If you are pregnant or a nursing mother, it is advised to consult a doctor before using Closol-CZ Cream. Inform your doctor if you are allergic to Closol-CZ Cream or other medicines. Do not apply Closol-CZ Cream to broken skin or cuts. Do not swallow Closol-CZ Cream. In case of accidental swallowing, contact a nearby poison control centre or consult a doctor immediately. Avoid smoking or going near naked flames as Closol-CZ Cream catches fire and burns easily. If you have glaucoma, cataracts, diabetes, psoriasis, adrenal gland, or liver problems, inform your doctor before taking Closol-CZ Cream. Closol-CZ Cream is not recommended for use in neonates and infants (up to 2 years) as absorption by immature skin may be enhanced, and kidneys may be immature, leading to toxicity.
Diet & Lifestyle Advise
Habit Forming
Therapeutic Class
Closol-CZ Cream is a combination of three drugs, namely Clobetasol, Miconazole, and Zinc sulfate. Clobetasol acts inside skin cells and inhibits certain chemical messenger's release in the body that cause redness, itching, and swelling. Miconazole causes holes in the fungal cell membranes and kills fungi. Zinc sulfate is antiseptic and astringent that heals skin wounds and ulcers.
Closol-CZ Cream is for topical (for skin use) application only. Avoid Closol-CZ Cream contact with eyes, nose, and mouth. Do not put a bandage or a dressing on the affected area while using Closol-CZ Cream unless advised by the doctor.
Closol-CZ Cream should be used with proper caution and doctor consultation if you have any active infections, history of liver, kidney diseases, glaucoma, cataract, poor blood circulation, immune system problems, diabetes, and adrenal gland diseases.
Closol-CZ Cream consists of Clobetasol, a corticosteroid that affects blood sugar levels. It is advised to consult your doctor before using Closol-CZ Cream and monitor your blood sugar levels regularly.
Closol-CZ Cream is not recommended for diaper rash since Clobetasol may be rapidly absorbed and can cause adrenal suppression, Cushing's syndrome (high cortisol levels), and intracranial hypertension (increased pressure around the brain) in infants. Your baby's pediatrician will suggest other medicines for the treatment of diaper rash.
Closol-CZ Cream, when used for longer periods, can cause thinning and weakening of the skin. Please stop using Closol-CZ Cream and immediately consult your doctor if you notice these symptoms.
Closol-CZ Cream should be used with caution in children if prescribed by a doctor as Closol-CZ Cream contains a steroid and may increase the risk of Cushing’s syndrome, HPA axis suppression (suppression of inflammatory and immune responses), adrenal insufficiency, delayed growth, and weight gain. However, please consult a doctor before using Closol-CZ Cream in children.
Yes, fungal infection is a contagious skin condition that spreads from one person to another through direct skin-to-skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, it is recommended to avoid close direct contact until the infection is clear and avoid sharing things with the infected person as it can also spread the infection.
Drug-Drug Interactions Checker List
Special Advise
Disease/Condition Glossary
Fungal infection: It is a skin disease in which a fungus attacks the tissue and causes infection. Fungal infections may be contagious (spread from one person to another). Fungal infection symptoms include scaly skin, blisters, itching, swelling, irritation, and redness. Antifungal medicines are usually used to treat fungal infections. Avoid sharing things to prevent the spread of infection. Keep the affected area clean and dry, wear flip-flops or sandals in locker rooms and avoid tight-fitting shoes or clothes to prevent fungal infections.