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  3. Clostran Sachet 9gm

Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
COD available

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Composition :

CHOLESTYRAMINE-4GM

Manufacturer/Marketer :

Medi Globe Corporation

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Clostran Sachet 9gm

Clostran Sachet 9gm belongs to the class of cholesterol-lowering medicines called bile acid-binding resins primarily used to lower bad cholesterol levels, thereby reducing the risk of heart attack and stroke in future. Clostran Sachet 9gm also treats itching caused by a blockage in the gallbladder's bile ducts. High cholesterol, known as hyperlipidaemia or dyslipidemia, occurs when there is an excess of the unhealthy balance of cholesterol in the blood. When the cholesterol level is high in the blood, your arteries get narrowed and clogged, contributing to heart diseases like stroke and heart attack.

Clostran Sachet 9gm contains Cholestyramine that works by binding to bile acids which aid fat digestion in the intestine and prevent its reabsorption into the bloodstream, thereby excreting it via faeces. This, in turn, triggers the liver to produce more bile acids from the blood's cholesterol and decreases bad cholesterol (LDL) levels in the blood. Thus, Clostran Sachet 9gm reduces the risk of stroke or heart attack by reducing the brain's excess cholesterol deposition and the heart's major blood vessels.

Take Clostran Sachet 9gm as instructed by your doctor. Some people may experience constipation, nausea, vomiting, diarrhoea, stomach pain or flatulence (gas). Most of these side effects of Clostran Sachet 9gm do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are allergic to Clostran Sachet 9gm or any other medicines, please tell your doctor. Before taking Clostran Sachet 9gm, please consult a doctor if you are pregnant or breastfeeding. Clostran Sachet 9gm is not recommended for children below 6 years of age, as the safety and effectiveness were not established. Avoid taking Clostran Sachet 9gm if you have gallstones or blockage in the stomach or intestines. You are recommended to take other medicines 1 hour before or 4-6 hours after taking Clostran Sachet 9gm as taking at the same time may reduce the effectiveness of other medicines. 

Uses of Clostran Sachet 9gm

Hyperlipidemia (high cholesterol), Prevention of heart attack and stroke

Directions for Use

Take Clostran Sachet 9gm as instructed by your doctor. Sprinkle the contents in 150 ml of fruit juice, water, skimmed milk, fruit smoothies, sauces (apple sauce) or thin soups. Then allow it to stand for 1 or 2 minutes. Stir or shake it to mix in thoroughly and drink immediately.

Medicinal Benefits

Clostran Sachet 9gm contains Cholestyramine that binds to bile acids (help in the digestion of fats consumed in the diet) in the intestine and removes them from the body. This makes the liver to produce more bile acids from the cholesterol in the blood and decreases cholesterol levels. Also, Clostran Sachet 9gm reduces the risk of stroke or heart attack by reducing the excess cholesterol deposition in the major blood vessels of brain and heart.

Storage

Store in a cool and dry place away from sunlight
Side effects of Clostran Sachet 9gm
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
  • Weak and brittle bones can be strengthened by regular exercise, like swimming, walking, and yoga.
  • Physical therapy, including stretching, strengthening exercises, TENS (a type of therapy using electrical pulses), and gentle massage, can help enhance and improve movement.
  • Swallow calcium-rich foods to make bones strong.
  • Rest well and avoid sudden jerky movements, which may lead to fractures.
  • Walk slowly and refrain from lifting heavy objects.

Drug Warnings

If you are allergic to Clostran Sachet 9gm or any other medicines, please tell your doctor. Before taking Clostran Sachet 9gm, please consult a doctor if you are pregnant or breastfeeding. Clostran Sachet 9gm is not recommended for children below 6 years of age, as the safety and effectiveness were not established. Maintain a low-fat diet along with Clostran Sachet 9gm for effective results. Avoid taking Clostran Sachet 9gm if you have gall stones or blockage in the stomach or intestines.  If you have diabetes, thyroid disorder, kidney, liver or heart problems, inform your doctor before taking Clostran Sachet 9gm. You are recommended to take other medicines 1 hour before or 4 to 6 hours after taking Clostran Sachet 9gm as taking at the same time may reduce the effectiveness of other medicines. Drink plenty of water while taking Clostran Sachet 9gm to prevent constipation as one of the side effect of Clostran Sachet 9gm in some cases. 

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Clostran Sachet 9gm:
Co-administration of Mycophenolic acid and Clostran Sachet 9gm may decrease the effectiveness of Mycophenolic acid.

How to manage the interaction:
Although there is an interaction between Mycophenolic acid and Clostran Sachet 9gm, it can be taken together if your doctor has prescribed them. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Clostran Sachet 9gm:
Co-administration of Clostran Sachet 9gm and teriflunomide may interfere with the effectiveness of teriflunomide.

How to manage the interaction:
Although taking Clostran Sachet 9gm and teriflunomide together can result in an interaction, they can be taken together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
CholestyramineMycophenolate Mofetil
Severe
How does the drug interact with Clostran Sachet 9gm:
Co-administration of Clostran Sachet 9gm and mycophenolate mofetil may interfere with the action of mycophenolate mofetil.

How to manage the interaction:
Although taking Clostran Sachet 9gm and mycophenolate mofetil together can result in an interaction, they can be taken together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Clostran Sachet 9gm:
Concomitant use of Clostran Sachet 9gm with calcitriol may decrease the effects of calcitriol.

How to manage the interaction:
Although there is an interaction, calcitriol can be taken with Clostran Sachet 9gm if prescribed by the doctor. However, calcitriol should be taken at least 4 hours before Clostran Sachet 9gm.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a low-fat diet. Limit your intake of dairy products made with whole milk and red meat. Prefer skim milk and fat-free or low-fat dairy products.
  • Eat a healthy diet that includes fruits, vegetables, fish, poultry, whole grains, nuts and cut down beverages, processed and sugary foods.
  • Do regular exercise such as swimming, cycling, walking or dancing and focus on losing weight as obesity also raises bad cholesterol and lowers good cholesterol.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

BILE ACID SEQUESTRANTS

Clostran Sachet 9gm Substitute

Substitutes safety advice

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Clostran Sachet 9gm contains Cholestyramine that binds to bile acids (help in the digestion of fats consumed in the diet) in the intestine and removes them from the body. This makes the liver to produce more bile acids from the cholesterol in the blood and decreases cholesterol levels. Also, Clostran Sachet 9gm reduces the risk of stroke or heart attack by reducing the excess cholesterol deposition in the major blood vessels of brain and heart.

You are not recommended to take Clostran Sachet 9gm with levothyroxine at the same time as it may reduce the absorption of levothyroxine and decrease its effectiveness. Therefore, you are recommended to take levothyroxine after 4 hours of taking Clostran Sachet 9gm. However, please consult a doctor before taking Clostran Sachet 9gm with any other medicines.

Clostran Sachet 9gm may be used to treat certain types of diarrhoea such as bile acid diarrhoea in which excess bile acids spill into the large intestine and trigger watery and loose stools. However, please consult a doctor before taking Clostran Sachet 9gm.

Clostran Sachet 9gm decreases the absorption of certain vitamins such as fat-soluble vitamins (A, D and K) by the body especially when taken in high doses or for long period. Therefore, your doctor may recommend you to take vitamin supplements with Clostran Sachet 9gm.

You are not recommended to stop taking Clostran Sachet 9gm without consulting your doctor as it may worsen the condition and increase the risk of heart attack and stroke. Therefore, take Clostran Sachet 9gm for as long as your doctor has recommended it, and if you experience any difficulty while taking Clostran Sachet 9gm, please consult your doctor so that the dose may be gradually reduced.

Clostran Sachet 9gm may cause constipation as a common adverse effect. You are advised to drink plenty of fluids while taking Clostran Sachet 9gm to prevent constipation. However, if the condition persists or worsens, please consult a doctor.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • LEVOTHYROXINE
  • ACETAMINOPHEN
  • CHOLECALCIFEROL

Special Advise

Regular blood tests are recommended while taking Clostran Sachet 9gm to monitor cholesterol levels in the blood and kidney functioning.

Disease/Condition Glossary

High cholesterol: Also known as hyperlipidemia or dyslipidemia occurs when there is an excess of the unhealthy balance of cholesterol in the blood. When there is a high cholesterol level in the blood, your arteries get narrowed and clogged that finally contributing to heart diseases, like stroke and heart attack. Eating high-fat or high-cholesterol-containing food/drinks and genetic factors are the primary causes of high cholesterol. There are two types of cholesterol found in our body: good cholesterol (high-density lipoprotein) and bad cholesterol (low-density lipoprotein). Good cholesterol is good for our heart and helps in reducing the bad cholesterol in our body. On the other hand, excess bad cholesterol (LDL) leads to the risk of heart diseases like heart attack and stroke.

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