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About Clotak MR Tablet

Clotak MR Tablet belongs to the class of drugs known as 'non-steroidal anti-inflammatory drug' (NSAID). Clotak MR Tablet is used in the reduction of musculoskeletal pain due to tissue injury, resolution of post surgery inflammation and oedema (swollen tissue with fluid). Pain can be temporary (acute) or long term(chronic) in nature. Musculoskeletal pain can be caused due to soft tissues (muscle, tendon, and ligaments) injury. Extreme tissue pain and inflammation caused due to sprains, strains or trauma or post-surgery may require a prolonged amount of time to heal.

Clotak MR Tablet is a fixed-dose combination composed of three medicines namely: Diclofenac, Paracetamol and Chlorzoxazone. Diclofenac works by blocking the action of a chemical messenger known as cyclo-oxygenase (COX) which causes pain and swelling at the injured or damaged tissue site. Paracetamol acts as a mild analgesic (mild pain reducer) and antipyretic (fever reducer) which enhances the pain relief action of Diclofenac. Third medicine i.e. Chlorzoxazone is a muscle relaxant, helps by blocking nerve impulses or pain sensations sent by the brain and causes relaxation of muscles.

Clotak MR Tablet can be taken with or after the meal. To avoid stomach upset Clotak MR Tablet can be taken with food or milk. It should be swallowed whole with a glass of water. Do not take Clotak MR Tablet if your pain lasts for more than ten days or fever lasting for more than three days. Do not take a double dose if you missed one dose. Like all medicines, Clotak MR Tablet may cause side effects, although not everybody gets them. Most of the side effects of Clotak MR Tablet are drowsiness, constipation, diarrhoea, stomach upset, slight discolouration of urine, and ringing or buzzing sounds in the ears. In case of any discomfort, speak with your doctor. 

Do not take Clotak MR Tablet if you are allergic to painkillers like aspirin, paracetamol, naproxen or diclofenac. It is not recommended for use in children, people with liver disease, heart disease or gastric ulcers/bleeding problems. Clotak MR Tablet may be associated with a small increase in the risk of heart attack (myocardial infarction). Avoid consumption of alcohol as it may damage your liver and cause even more side effects on taking this drug. Consult your doctor if your symptoms of pain, inflammation and fever do not disappear even after ten days.

Uses of Clotak MR Tablet

Musculoskeletal pain.

Directions for Use

Take Clotak MR Tablet as advised by your doctor. Preferably take it with a light meal. Swallow it as a whole, do not chew or crush it.

Medicinal Benefits

Clotak MR Tablet is composed of three medicines namely: Diclofenac, Paracetamol and Chlorzoxazone. Diclofenac works by blocking the action of a chemical messenger known as cyclo-oxygenase (COX) which causes pain and swelling at the injured or damaged tissue site. Paracetamol acts as a mild analgesic (mild pain reducer) and antipyretic (fever reducer) which enhances the pain relief action of Diclofenac. Third medicine i.e. Chlorzoxazone is a muscle relaxant, helps by blocking nerve impulses or pain sensations sent by the brain and causes relaxation of muscles.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Intake of Clotak MR Tablet should be avoided in liver disease (like jaundice) and cardiovascular disease (like coronary heart disease). Contact your doctor if you have signs of liver disease like feeling exhausted, dark urine, not feeling hungry, stomach pain or upset, light coloured stools or yellow skin/eyes. After taking if you have possible allergic symptoms like difficulty in breathing, difficulty in swallowing, lips/face/throat swelling, chest tightness, or skin rash, contact the doctor immediately. Ensure your doctor is aware if you are pregnant or planning to get pregnant, breastfeeding, allergic to Clotak MR Tablet or any other painkillers like aspirin, the problem of stomach ulcer or gastric bleeding, or taking any other OTC multivitamins, multi-minerals supplements.

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
ParacetamolKetamine
Severe

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
How does the drug interact with Clotak MR Tablet:
Co-administration of Clotak MR Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Clotak MR Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
ParacetamolKetamine
Severe
How does the drug interact with Clotak MR Tablet:
Co-administration of ketamine and Clotak MR Tablet may decrease the effectiveness of Ketamine which could result in a higher blood level.

How to manage the interaction:
Although taking Ketamine and Clotak MR Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
ParacetamolLomitapide
Severe
How does the drug interact with Clotak MR Tablet:
Co-administration of Lomitapide and Clotak MR Tablet may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Clotak MR Tablet and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolMipomersen
Severe
How does the drug interact with Clotak MR Tablet:
Co-administration of Mipomersen with Clotak MR Tablet may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Clotak MR Tablet and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ParacetamolOxazepam
Severe
How does the drug interact with Clotak MR Tablet:
Co-administration of Clotak MR Tablet may decrease the excretion rate of Oxazepam which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Oxazepam and Clotak MR Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolKetoconazole
Severe
How does the drug interact with Clotak MR Tablet:
Co-administration of Clotak MR Tablet and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Clotak MR Tablet and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.
ParacetamolLeflunomide
Severe
How does the drug interact with Clotak MR Tablet:
Co-administration of Clotak MR Tablet and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Clotak MR Tablet and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ParacetamolTeriflunomide
Severe
How does the drug interact with Clotak MR Tablet:
Co-administration of Teriflunomide with Clotak MR Tablet may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Clotak MR Tablet with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
ParacetamolValdecoxib
Severe
How does the drug interact with Clotak MR Tablet:
Co-administration of Clotak MR Tablet and Valdecoxib may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Clotak MR Tablet and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.
ChlorzoxazoneTapentadol
Severe
How does the drug interact with Clotak MR Tablet:
Taking Tapentadol with Clotak MR Tablet can increase the risk or severity of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.

How to manage the interaction:
Taking Clotak MR Tablet with Tapentadol can result in an interaction, it can be taken if your doctor has advised it. Contact a doctor immediately if you experience signs such as drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Clotak MR Tablet is commonly prescribed for relieving pain in both acute and chronic conditions and in cases of fever. Do not take the drug beyond its suggested dose and frequency.
  • Avoid driving while consuming Clotak MR Tablet as it can cause dizziness in some individuals and hamper your focus and reflexes.
  • Avoid concomitant consumption of drugs containing the same chemicals as Clotak MR Tablet as it can lead to overdosage and unwanted side effects.
  • Immediately consult your doctor in case of persistent side effects like stomach pain on consumption of Clotak MR Tablet.
  • Avoid consuming alcohol while you are on Clotak MR Tablet.

Habit Forming

No

Therapeutic Class

ANALGESICS

Clotak MR Tablet Substitute

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

No, Clotak MR Tablet should not be taken as a long term medication as it may lead to stomach ulcers/bleeding and kidney problems. For best results of Clotak MR Tablet, take it in doses and duration mentioned by your doctor.

No, it is not advisable to take Clotak MR Tablet with depression medication. Please inform your doctor if you are taking depression medicine before starting Clotak MR Tablet.

Yes, Clotak MR Tablet is a short term medication and if you feel better you can stop taking Clotak MR Tablet, but only after consulting your doctor.

Clotak MR Tablet is known to be contra-indicated in patients with allergy to painkillers (NSAIDs) or any of the components or excipients of this medicine. Its use should also be avoided in patients with history of stomach ulcer and kidney/liver disease.

Yes, Clotak MR Tablet is known to cause dizziness. If you feel dizzy, please take rest and also avoid driving while you take Clotak MR Tablet as it can be harmful.

No, Clotak MR Tablet is not indicated for stomach pain. Also, If you have stomach pain post ingestion it may be a sign of stomach ulcer or gastric bleeding. Do not take Clotak MR Tablet in this condition. It is better to inform your doctor in case of stomach pain post ingestion of this medication.

It depends on whether your cough and cold pills contains diclofenac, paracetamol and Chlorzoxazone or not. If it contains these three medicines, do not take it. It may lead to overdosage, thereby producing unpleasant side effects. Consult your doctor before taking it in such cases.

No, do not take Clotak MR Tablet until prescribed by your doctor. For example, your shoulder pain may be due to lungs, spleen or gallbladder problem. Your back pain may be due to kidney stone, pancreas swelling, or in women, pelvic disorders. Your arm pain (especially left arm) may be due to heart attack (myocardial infarction).

Drug-Drug Interactions Checker List

  • NAPROXEN
  • ASPIRIN
  • IBUPROFEN
  • TRAMADOL
  • HYDROCODONE
  • OXYCODONE
  • LISINOPRIL
  • HYDROCHLOROTHIAZIDE
  • RIVAROXABAN
  • WARFARIN
  • DULOXETINE
  • CIMETIDINE
  • PREDNISONE

Special Advise

  • Clotak MR Tablet is prescribed for relief from muscle pain and spasms.
  • It can cause drowsiness and hence activities involving focus and attention like driving must be avoided while on this medication.
  • Concomitant usage of alcohol with this medicine increase the risk of damage to liver and other side effects and hence alcohol consumption should be avoided while consuming this medication
  • Avoid simultaneous consumption of other painkillers or cough and cold medicines with this Clotak MR Tablet as it may lead to overdose.

Disease/Condition Glossary

Musculoskeletal pain is generally caused by disorders of bones, joints, muscles, tendons, ligaments, or a combination. Injuries (mostly sports related injury) are the most common cause of musculoskeletal pain. Muscle pain (myalgia) can be caused due to injury, infection, loss of blood flow to the muscle, infection, or a tumour. Extreme tissue pain and inflammation caused due to sprains, strains, or trauma or post-surgery may require a prolonged amount of time to heal

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