COLIGAN TABLET

Written By Santoshini Reddy G , M Pharmacy

Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Prescription drug

MRP ₹12

(Inclusive of all Taxes)

₹1.8 Cashback (15%)

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Whats That

About COLIGAN TABLET

COLIGAN TABLET is a combination medicine used to treat abdominal pain, dysmenorrhea (period pain), and colicky pain. Abdominal (tummy) pain occurs between the chest and pelvic region (below the belly button and leg). Menstrual cramps, also known as dysmenorrhea, are characterised by cramps and pain during menstruation. Colic is a form of pain that starts and stops abruptly.

COLIGAN TABLET is a combination of two drugs: Dicyclomine (anti-spasmodic) and Mefenamic acid (NSAID). Dicyclomine works by relieving contractions associated with the smooth muscles of the abdomen. Mefenamic acid works by blocking the effect of chemical messengers called prostaglandins. This helps reduces mild to moderate pain and inflammation at the injured or damaged site. Together, COLIGAN TABLET helps in relieving pain.

You are advised to take COLIGAN TABLET for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, COLIGAN TABLET may cause common side effects such as nausea, vomiting, diarrhoea, dry mouth, and weakness. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor if you are pregnant or breastfeeding. COLIGAN TABLET may cause dizziness and drowsiness, so drive with caution. COLIGAN TABLET is not recommended for children as safety and efficacy have not been established. Avoid consuming alcohol with COLIGAN TABLET as it could lead to increased drowsiness and dizziness, it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side-effects/interactions.

Uses of COLIGAN TABLET

Abdominal pain, dysmenorrhea (period pain), colicky pain

Directions for Use

Take COLIGAN TABLET with food to prevent stomach upset. Swallow COLIGAN TABLET as a whole with a glass of water, do not chew or break it.

Medicinal Benefits

COLIGAN TABLET is a combination of two drugs, namely: Dicyclomine (anti-spasmodic) and Mefenamic acid (NSAID). COLIGAN TABLET is used to treat abdominal pain, dysmenorrhea (period pain), and colicky pain. Dicyclomine works by relieving contractions associated with the smooth muscles of the abdomen. Mefenamic acid works by blocking the effect of chemical messengers called prostaglandins. This helps reduce mild to moderate pain and inflammation at the injured or damaged site. Together, COLIGAN TABLET helps in relieving pain.

Storage

Keep COLIGAN TABLET out of reach and sight of children.

Side effects of Coligan Tablet

Dry Mouth

Here are the steps to Dry Mouth (xerostomia) caused by medication:

Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Dizziness

Here are the 7 steps to manage Dizziness caused by medication:

Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
When standing up, do so slowly and carefully to avoid sudden dizziness.
Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Drowsiness

Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.

Weakness

Rest well; get enough sleep.
Eat a balanced diet and drink enough water.
Manage stress with yoga and meditation.
Limit alcohol and caffeine.
Physical activities like walking or jogging might help boost energy and make you feel less tired.

Nervousness

Here are the steps to manage medication-triggered Nervousness:

Tell your doctor immediately if you experience symptoms of Nervousness, such as anxiety, jitteriness, or an increased heart rate, after taking medication or adjusting your medication regimen.
Your doctor may adjust your medication regimen to alleviate symptoms of Nervousness. This can include switching to a different medication, reducing the dosage, or temporarily stopping the medication. Your doctor may also recommend alternative techniques like relaxation, mindfulness meditation, or journaling. These techniques can help reduce anxiety and Nervousness.
Practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling, to help manage Nervousness.
Engage in regular physical activity, such as walking or jogging, to help reduce anxiety and improve mood.
Your doctor may advise considering cognitive-behavioural therapy (CBT) or other forms of talk therapy to address underlying anxiety or Nervousness.
You should maintain regular follow-up appointments with your doctor to monitor nervousness symptoms, adjust treatment plans as needed, and discuss any concerns or questions.

Stomach Pain

Drink water or other clear fluids.
To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
Include bland foods like rice, toast, crackers, and rice in your diet.
Avoid lying down immediately after eating as it may cause indigestion or heartburn.
Avoid acidic and spicy food as it may cause indigestion.

Drug Warnings

Do not take COLIGAN TABLET if you are allergic to any of its contents, if you have severe heart failure, or have suffered bleeding problems such as bleeding from the stomach or bowels while taking any painkillers. Inform your doctor if you have/had asthma, glaucoma, myasthenia gravis, high blood pressure, inflammatory bowel disease, paralytic ileus, intestinal atony, heart, kidney, or liver problems. Consult your doctor if you are pregnant or breastfeeding. COLIGAN TABLET may cause dizziness and drowsiness, so drive only if you are alert. COLIGAN TABLET should not be given to children as safety has not been established. Avoid consuming alcohol with COLIGAN TABLET as it could lead to increased drowsiness and can increase the risk of stomach bleeding. Stop taking COLIGAN TABLET and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take any other NSAIDs for pain relief along with COLIGAN TABLET unless prescribed.

Drug-Drug Interactions

Mefenamic acidMeloxicam

Critical

Mefenamic acidKetorolac

Critical

Drug-Drug Interactions

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Mefenamic acidMeloxicam

Critical

How does the drug interact with Coligan Tablet:
Co-administration of Coligan Tablet with Meloxicam together can increase the risk or severity of bleeding.

How to manage the interaction:
Taking Coligan Tablet with Meloxicam together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking a doctor.

Mefenamic acidKetorolac

Critical

How does the drug interact with Coligan Tablet:
Coadministration of Coligan Tablet with Ketorolac can increase the risk or severity of gastric bleeding and ulcers.

How to manage the interaction:
Taking Coligan Tablet with Ketorolac together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.

DicyclominePramlintide

Critical

How does the drug interact with Coligan Tablet:
Co-administration of Pramlintide with Coligan Tablet can increase the risk of reduced gastrointestinal movement.

How to manage the interaction:
Taking Coligan Tablet with Pramlintide is not recommended, please consult your doctor before taking it. Do not discontinue the medication without consulting a doctor.

DicyclominePotassium citrate

Critical

How does the drug interact with Coligan Tablet:
Taking Coligan Tablet and Potassium citrate together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Coligan Tablet with Potassium citrate is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.

DicyclominePotassium chloride

Critical

How does the drug interact with Coligan Tablet:
Co-administration of Coligan Tablet with Potassium chloride can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Coligan Tablet with Potassium chloride is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not discontinue the medication without consulting a doctor.

Mefenamic acidDasatinib

Severe

How does the drug interact with Coligan Tablet:
Co-administration of Coligan Tablet with Dasatinib can increase the risk or severity of bleeding.

How to manage the interaction:
Taking Coligan Tablet with Dasatinib together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness, lightheadedness, red or black tarry stools, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Mefenamic acidIndometacin

Severe

How does the drug interact with Coligan Tablet:
The combined use of Indometacin and Coligan Tablet can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
Taking Indometacin with Coligan Tablet together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.

Mefenamic acidFlurbiprofen

Severe

How does the drug interact with Coligan Tablet:
Co-administration of Coligan Tablet with Flurbiprofen can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Coligan Tablet with Flurbiprofen together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of dizziness, lightheadedness, unusual bleeding or bruising, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Mefenamic acidTenofovir alafenamide

Severe

How does the drug interact with Coligan Tablet:
The combined use of Coligan Tablet and Tenofovir alafenamide can increase the risk of kidney problems.

How to manage the interaction:
Taking Coligan Tablet and Tenofovir alafenamide together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Mefenamic acidIbrutinib

Severe

How does the drug interact with Coligan Tablet:
Co-administration of Coligan Tablet with Ibrutinib can increase the risk or severity of bleeding, leading to serious blood loss.

How to manage the interaction:
Taking Coligan Tablet with Ibrutinib together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any symptoms of unusual bleeding or bruising, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
Massages can also be helpful.
Avoid freezing and hot temperatures.
Avoid wearing tight-fitting clothes, instead, wear loose garments.
Rest well, and get plenty of sleep.
To avoid developing pressure sores, change your position every two hours.
Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.
Stay hydrated, drink plenty of water.

Side Effects of COLIGAN TABLET

Nausea
Vomiting
Diarrhoea
Dizziness
Headache
Dry mouth
Weakness
Nervousness
Loss of appetite

Habit Forming

No

Therapeutic Class

ANTISPASMODICS

COLIGAN TABLET Substitute

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Author Details

Written By

Santoshini Reddy G

M Pharmacy

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 8, 2025 | 9:34 AM IST

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does COLIGAN TABLET work?

COLIGAN TABLET contains Dicyclomine and Mefenamic acid. Dicyclomine works by relieving contractions associated with the smooth muscles of the abdomen. Mefenamic acid works by blocking the action of certain chemical messengers that cause pain.

Does COLIGAN TABLET cause diarrhoea?

Diarrhoea might be a side-effect of COLIGAN TABLET. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience severe diarrhoea or if you find blood in your stools.

Is COLIGAN TABLET used to treat colicky pain?

COLIGAN TABLET is used to treat colicky pain. Colic is a pain that is usually intestinal or urinary in nature that comes and goes and intensifies and eases gradually.

How to cope with dry mouth?

Dry mouth could be a side-effect of COLIGAN TABLET. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help stimulate saliva and thereby prevents drying of the mouth.

Can I take COLIGAN TABLET for longer durations?

COLIGAN TABLET should not be taken for more than 7days. Do not take COLIGAN TABLET for longer durations as it might increase the risk of heart problems and stomach bleeding.

Is COLIGAN TABLET used to treat period pain?

COLIGAN TABLET is used to treat dysmenorrhea (period pain), pain due to heavy bleeding during periods, and menstrual cramps. Take COLIGAN TABLET only as prescribed, and do not overdose.

Drug-Drug Interactions Checker List

ASPIRIN
FUROSEMIDE
LITHIUM
QUINIDINE
PHENOTHIAZINE
METHOTREXATE
WARFARIN
CLOPIDOGREL
DIGOXIN
GLIMEPIRIDE
GLICLAZIDE
GLIBENCLAMIDE
GENTAMICIN
TOBRAMYCIN
AMIKACIN
CYCLOSPORINE
MIFEPRESTONE
TACROLIMUS
ZIDOVUDINE
METOCLOPRAMIDE

Special Advise

COLIGAN TABLET may prolong prothrombin time (blood test to measure blood clotting time). Therefore, frequent monitoring of prothrombin time is advised while taking COLIGAN TABLET.
COLIGAN TABLET may cause a false-positive reaction for urinary bile test. Inform the person doing the test that you are taking COLIGAN TABLET.

Disease/Condition Glossary

Abdominal pain and cramps: Abdominal pain occurs between the chest and pelvic region, generally known as stomach or tummy pain. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms. The common causes of abdominal pain include inflammation, infections, intestinal disorders, and obstruction/blockage.

Dysmenorrhea: Menstrual cramps, also known as dysmenorrhea, is characterised by cramps and pain during menstruation due to heavy flow. Pain, cramps, and discomfort during periods are normal. However, excessive pain during periods is not normal and requires medication. Menstrual cramps cause throbbing, aching pain in the lower belly that occurs before or during the periods.