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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

rxMedicinePrescription drug

Whats That

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Synonym :

COLISTIN

Manufacturer/Marketer :

Aishwarya Healthcare

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Colsimit 1000000IU Injection

Colsimit 1000000IU Injection belongs to the class of medications called ‘antibiotics’ used to treat bacterial infections. Bacterial infections are caused by the multiplication of harmful bacteria inside or on the body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. Symptoms of bacterial infection vary depending on the organ affected by bacteria.

Colsimit 1000000IU Injection contains Colistimethate Sodium. Colistimethate Sodium effectively solubilizes the bacterial cell membrane, resulting in bacterial cell death. As a result, Colsimit 1000000IU Injection destroys the bacteria and successfully treats the infection.

Colsimit 1000000IU Injection will be administered by a qualified healthcare professional. Sometimes, you may experience common side effects like injection site reactions, renal damage, visual disturbances, GI disturbances, dizziness, nausea, vomiting and muscle weakness. But these side effects are usually in the initial phase and resolve over time. However, if these side effects persist, let your doctor know.

Before receiving Colsimit 1000000IU Injection, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. And also, inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. Colsimit 1000000IU Injection can cause blurred vision and dizziness in some people; if this occurs, do not drive or operate tools or machinery. It is recommended not to consume any alcoholic beverages while on treatment with this medicine.

Uses of Colsimit 1000000IU Injection

Bacterial infections

Directions for Use

Colsimit 1000000IU Injection will be administered by a qualified healthcare professional. Do not self-administer.

Medicinal Benefits

Colsimit 1000000IU Injection contains Colistimethate Sodium. Colistimethate Sodium, also known as polymyxin E, is an antibiotic medication used as a last-resort treatment for multidrug-resistant Gram-negative infections. Colistimethate Sodium essentially solubilizes the bacterial cell membrane, resulting in bacterial cell death. As a result, Colsimit 1000000IU Injection kills the bacteria and effectively treats the infection. In addition, it can also treat infectious diarrhoea and urinary tract infections.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Colsimit 1000000IU Injection, please inform your physician. Inform your doctor about your medical history and other medications you are currently taking to rule out any potential negative effects. Inform your doctor if you are pregnant, planning to become pregnant, or are breastfeeding before receiving Colsimit 1000000IU Injection. Also, inform your doctor if you have chronic kidney disease, myasthenia gravis (muscle disorder), and porphyria (a blood disorder). Do not abruptly discontinue taking the prescription since this may result in antibiotic resistance, a condition in which bacteria develop resistance to antibiotics.

Drug-Drug Interactions

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ColistinBCG vaccine
Critical

Drug-Drug Interactions

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ColistinBCG vaccine
Critical
How does the drug interact with Colsimit 1000000IU Injection:
Coadministration of Colsimit 1000000IU Injection along with BCG vaccine can reduce the treatment outcomes.

How to manage the interaction:
Taking Colsimit 1000000IU Injection with BCG vaccine is avoided as it may lead to an interaction, please consult your doctor before taking it.
How does the drug interact with Colsimit 1000000IU Injection:
Coadministration of Colsimit 1000000IU Injection with Amikacin can increase the risk of developing side effects.

How to manage the interaction:
Although there is a possible interaction between Colsimit 1000000IU Injection and Amikacin, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Colsimit 1000000IU Injection:
Using Suxamethonium together with Colsimit 1000000IU Injection may increase the effects of Suxamethonium.

How to manage the interaction:
Although there is a possible interaction between Colsimit 1000000IU Injection and Suxamethonium, you can take these medicines together if prescribed by your doctor. However, if you experience an upset stomach, Rash Paresthesia (tingling or pricking sensation) Dizziness Slurred speech Vertigo, or Fever, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Colsimit 1000000IU Injection:
Coadministration of Colsimit 1000000IU Injection with Everolimus can increase the risk of developing kidney problems.

How to manage the interaction:
Although there is a possible interaction between Colsimit 1000000IU Injection and Everolimus, it can be taken if prescribed by a doctor. However, if you experience vomiting, irregular urination, sudden weight gain or loss, swelling, shortness of breath, or weakness, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Colsimit 1000000IU Injection:
Combining Colsimit 1000000IU Injection with Adefovir dipivoxil may decrease Colsimit 1000000IU Injection's excretion rate, which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Colsimit 1000000IU Injection and Adefovir dipivoxil, you can take these medicines together if prescribed by your doctor. However, if you experience any irregular urination, swelling, shortness of breath, muscle pain, dizziness, or palpitations call your doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Colsimit 1000000IU Injection:
Combining Colsimit 1000000IU Injection with Neomycin can increase the risk or severity of kidney problems.

How to manage the interaction:
Although there is a possible interaction between Colsimit 1000000IU Injection and Neomycin, you can take these medicines together if prescribed by your doctor. However, if you experience an upset stomach, Rash, Dizziness, or Fever, consult a doctor. Do not stop using any medications without a doctor's advice.
ColistinIohexol
Severe
How does the drug interact with Colsimit 1000000IU Injection:
Combining Colsimit 1000000IU Injection with Iohexol can increase the effect or side effects of Iohexol.

How to manage the interaction:
Although there is a possible interaction between Colsimit 1000000IU Injection and Iohexol, you can take these medicines if prescribed by your doctor. However, if you experience vomiting, loss of appetite, irregular urination, swelling, shortness of breath, muscle cramps, or weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Colsimit 1000000IU Injection:
Co-administration of Colsimit 1000000IU Injection with Gentamicin can increase the levels and risk of Colsimit 1000000IU Injection side effects.

How to manage the interaction:
Although there is a possible interaction between Colsimit 1000000IU Injection and Gentamicin, you can take these medicines together if prescribed by your doctor. However, if you experience weight gain or loss suddenly, muscle pain, dizziness, or palpitations, call your doctor right away. Do not stop using any medications without a doctor's advice.
ColistinCisatracurium
Severe
How does the drug interact with Colsimit 1000000IU Injection:
Coadministration of Cisatracurium with Colsimit 1000000IU Injection may increase the risk of side effects of Cisatracurium.

How to manage the interaction:
Although there is a possible interaction of Cisatracurium with Colsimit 1000000IU Injection, it can be taken if prescribed by your doctor. However, if you experience an upset stomach, Rash, Dizziness, Slurred speech, Vertigo, or Fever, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Colsimit 1000000IU Injection:
Combining Colsimit 1000000IU Injection with Tenofovir alafenamide may increase the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between Colsimit 1000000IU Injection and Tenofovir alafenamide, you can take these medicines together if prescribed by your doctor. However, consult a doctor if you experience an upset stomach, rash, dizziness, or fever. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • After taking the full course of Colsimit 1000000IU Injection, probiotics should be taken to restore some of the healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can restore the intestine's good bacteria stink.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Thus fibre foods may help restore healthy gut bacteria after taking a course of antibiotics. Whole grains, like whole-grain bread, and brown rice, should be included in your diet.
  • Avoid taking many calcium-enriched foods and drinks as it might affect the working of Colsimit 1000000IU Injection.
  • Avoid intake of alcoholic beverages with Colsimit 1000000IU Injection as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Colsimit 1000000IU Injection in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTI- BACTERIALS

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Drug-Drug Interactions Checker List

  • CYCLOBENZAPRINE
  • METAXALONE
  • AMPHOTERICIN B
  • CAPREOMYCIN
  • VANCOMYCIN

Special Advise

  • Regular blood tests are required to monitor kidney functions while taking Colsimit 1000000IU Injection.
  • A Healthcare professional should always give a Colsimit 1000000IU Injection to a hospital. Never self-administer.

Disease/Condition Glossary

Bacterial infections: A bacterial infection occurs when harmful bacteria enter the body, multiply, and infect it. It may attack any region of the body and multiply swiftly. Fever, chills, and tiredness are common symptoms. Bacteria come in a variety of shapes, including spherical, rod, and spiral-shaped bacteria. Bacterial infections range in severity from simple ailments such as sore throats and ear infections to serious brain infections such as meningitis and encephalitis. A bacterial infection can infect anyone at any time. People with a weakened immune system or who are on immunosuppressive medications, on the other hand, are more vulnerable to bacterial infection.

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