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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS

Composition :

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Consume Type :

Oral

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About Combantrin A Suspension

 Combantrin A Suspension belongs to a group of antiparasitic drugs called 'anthelmintic' used to treat parasites worm infections like neurocysticercosis (infection caused by pork tapeworm) and cystic hydatid disease (infection caused by dog tapeworm). Additionally, Combantrin A Suspension is also used to treat infections caused by roundworms, hookworms, threadworms, whipworms, pinworms, flukes, and other parasites. 

Combantrin A Suspension contains ‘Albendazole’, which works by inhibiting tubulin polymerisation. This causes metabolic disruption and energy depletion in the parasite, which leads to its immobilisation. Thereby, Combantrin A Suspension kills the susceptible helminth and treats the infection. 

Take Combantrin A Suspension as prescribed. You are advised to take Combantrin A Suspension for as long as your doctor has prescribed it for you, depending on your medical condition. You may experience certain common side effects, such as stomach pain, nausea, vomiting, headache, and dizziness in some cases. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Combantrin A Suspension might increase the chances of getting an infection; maintain proper hygiene, and try to stay away from people with infections, flu or colds. Consult your doctor if you notice unusual bleeding or bruising, as you may bleed or bruise easily while taking Combantrin A Suspension. Do not take Combantrin A Suspension if you are pregnant or planning for pregnancy as it may cause foetal harm. Do not breastfeed during and for a minimum of 5 days after treatment with Combantrin A Suspension. Combantrin A Suspension may cause dizziness, so be cautious while driving. Combantrin A Suspension can be given to children if prescribed by the doctor. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Combantrin A Suspension

Parasitic worm infections

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Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew or crush the tablet/capsule. Syrup/Suspension/Drops: Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper; shake the pack well before each use. Chewable tablet: Chew the tablet completely and swallow. Do not swallow it as a whole.

Key Benefits

Combantrin A Suspension belongs to a group of medicines called anthelmintic used to treat worm infections such as neurocysticercosis (infection caused by pork tapeworm) and cystic hydatid disease (infection caused by dog tapeworm). Combantrin A Suspension is also used to treat infections caused by roundworms, hookworms, threadworms, whipworms, pinworms, flukes, and other parasites. Combantrin A Suspension is a broad-spectrum anthelmintic drug which is highly effective against a wide range of intestinal helminths, including cestodes, nematodes, and trematodes. It is also effective against tissue helminth infections like cutaneous larva migrans (parasitic skin infections). Combantrin A Suspension exhibits ovicidal, larvicidal and vermicidal activity. Combantrin A Suspension inhibits tubulin polymerisation, which causes metabolic disruption and energy depletion in the parasite. This leads to the immobilisation of the parasite. Thereby, Combantrin A Suspension kills the susceptible helminth and treats the infection.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Combantrin A Suspension if you are allergic to any of its contents. Combantrin A Suspension may cause bone marrow suppression, aplastic anaemia, and agranulocytosis. Inform your doctor if you have/had liver disease; if you have any surgery, including dental surgery. Consult your doctor immediately if you experience seizures, vomiting, headache, extreme tiredness, or behaviour changes while taking Combantrin A Suspension. Regular blood cell count and liver function monitoring is advised during treatment with Combantrin A Suspension. Combantrin A Suspension might increase the chances of getting an infection; maintain proper hygiene, and try to stay away from people with infections, flu or cold. Consult your doctor if you notice unusual bleeding or bruising, as you may bleed or bruise easily while taking Combantrin A Suspension. Do not take Combantrin A Suspension if you are pregnant or planning for pregnancy as it may cause foetal harm. Do not breastfeed during and for minimum of 5 days after treatment with Combantrin A Suspension. Combantrin A Suspension may cause dizziness, so be cautious while driving. Combantrin A Suspension can be given to children if prescribed by the doctor.

Diet & Lifestyle Advise

  • Regularly wash your hands with soap and water, especially after using the toilet and while eating.
  • Avoid eating raw fish and meat.
  • Thoroughly cook meat before eating.
  • Wash all fruits and vegetables properly before consuming.
  • Wash or reheat food that has been around for a long time.
  • Avoid contact with soil that may be contaminated with faeces.
  • Avoid foods that have been kept open in the markets as they can be contaminated.
  • Drink boiled and purified water.

Habit Forming

No

Therapeutic Class

[ANTIHELMINTICS]

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Alcohol

Safe if prescribed

It is unknown whether alcohol interacts with Combantrin A Suspension. Please consult your doctor.

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Pregnancy

Consult your doctor

Combantrin A Suspension belongs to pregnancy category C. Do not take Combantrin A Suspension if you are pregnant or planning for pregnancy as it may cause foetal harm. Please consult your doctor if you have any concerns regarding this.

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Breast Feeding

Consult your doctor

Do not breastfeed during and for minimum 5 days after treatment with Combantrin A Suspension. Please consult your doctor if you have any concerns regarding this.

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Driving

Safe if prescribed

Combantrin A Suspension may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Consult your doctor

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Safe if prescribed

Combantrin A Suspension can be given to children if prescribed by the doctor. Please consult your doctor. Your doctor will prescribe the dose of this medicine based on the age and body weight of your child.

FAQs

Combantrin A Suspension causes metabolic disruption and energy depletion in the parasite, which leads to its immobilisation. Thereby, Combantrin A Suspension kills the susceptible helminth and treats the infection.

For neurocysticercosis, Combantrin A Suspension is usually prescribed for 8-30 days. For cystic hydatid disease, Combantrin A Suspension is usually prescribed for 28 days, followed by a 14 day break, and repeated for a total of 3 cycles.

Do not discontinue Combantrin A Suspension without consulting your doctor. To treat your condition effectually continue taking Combantrin A Suspension for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Combantrin A Suspension.

You are recommended to avoid planning for pregnancy while taking Combantrin A Suspension as it may cause foetal harm. A pregnancy test should be done before starting the treatment with Combantrin A Suspension, and women must use effective birth-control while taking Combantrin A Suspension and for at least 1month after cessation of treatment.

Regular monitoring of blood count at the beginning of each cycle therapy and for every 2weeks while taking Combantrin A Suspension is advised for all patients. Treatment with Combantrin A Suspension should be discontinued if a significant decrease in blood cell count is observed.

Treatment with Combantrin A Suspension has been associated with mild to moderate elevations of liver enzymes. These elevations generally return to normal upon discontinuation of Combantrin A Suspension. Liver function tests should be performed before each treatment cycle and for every 2weeks during the treatment. Treatment with Combantrin A Suspension should be discontinued if the liver enzymes exceed twice the upper limit of normal.

Combantrin A Suspension might increase the chances of getting an infection. Maintain proper hygiene and try to stay away from people with infections, flu or cold.

You may bleed or bruise easily while taking Combantrin A Suspension. Be cautious while using sharp objects and try to avoid injuries. Consult your doctor if you notice unusual bleeding or bruising.

Country of origin

India

Manufacturer/Marketer address

The Capital, 1802, 18Th Floor , Plot No. C-70, €˜G’ Block , Bandra Kurla Complex, Bandra East , Mumbai €“ 400051
Other Info - COM0001

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