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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
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Manufacturer/Marketer :

Zydus Cadila

Consume Type :

NASAL

Return Policy :

Not Returnable

Expires on or after :

About Combinase AQ Nasal Spray 70 mdi

Combinase AQ Nasal Spray 70 mdi belongs to the class of medications called 'anti-allergic' primarily used to treat allergic symptoms like sneezing, runny nose, congestion, stuffy nose, or watery eyes. An allergy is a condition that occurs when the immune system reacts to a foreign substance that is typically not harmful to your body. These foreign substances are known as ‘allergens.’ Allergic condition varies from person to person. Some might be allergic to certain foods and seasonal allergies like hay fever, pollen, or pet dander. One of the main symptoms of allergy is cough, and it acts as a reflex action in the throat when there is any mucus or foreign irritant entry into the respiratory system.

Combinase AQ Nasal Spray 70 mdi is a combination of two drugs, namely: Fluticasone propionate (corticosteroid) and Azelastine (antihistamine/antiallergic). Fluticasone propionate belongs to the class of corticosteroids that works by acting inside cells of the nasal lining and stops the release of certain chemicals in the body that cause inflammatory reactions thereby relieving sneezing, runny or blocked nose, and sinus discomfort. On the other hand, Azelastine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness.

Use Combinase AQ Nasal Spray 70 mdi as prescribed. Your doctor will recommend how often you take Combinase AQ Nasal Spray 70 mdi based on your medical condition. Some people may experience headache, taste changes, or nose bleeds. Most of these side effects of Combinase AQ Nasal Spray 70 mdi do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Combinase AQ Nasal Spray 70 mdi or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Combinase AQ Nasal Spray 70 mdi. Combinase AQ Nasal Spray 70 mdi is not recommended for children below 6 years of age. If you experience any changes in vision, tiredness, nausea, vomiting, light-headedness, chills, fever, body pains, sores, redness or white patches in the mouth or throat, runny nose, severe nosebleeds, or increased drowsiness, stop taking Combinase AQ Nasal Spray 70 mdi and consult a doctor immediately. Avoid contact with people who have infections or who are sick as Combinase AQ Nasal Spray 70 mdi may weaken the immune system causing infections easily. If you have chickenpox, measles, tuberculosis, surgery or injury on the nose, glaucoma, cataracts, herpes infection of the eyes, ulcers or sores inside the nose, inform your doctor before taking Combinase AQ Nasal Spray 70 mdi.

Uses of Combinase AQ Nasal Spray 70 mdi

Allergic symptoms

Directions for Use

Use Combinase AQ Nasal Spray 70 mdi as prescribed by your doctor. Check the label for directions before using Combinase AQ Nasal Spray 70 mdi. Insert the tip of the bottle into a nostril while closing the other nostril and spray Combinase AQ Nasal Spray 70 mdi towards the sides of the nostril. Keep your head straight and breathe gently. Repeat the same process for another nostril.

Medicinal Benefits

Combinase AQ Nasal Spray 70 mdi is a combination of two drugs, namely: Fluticasone propionate and Azelastine used to treat allergic symptoms such as sneezing, runny nose, congestion, stuffy nose, or watery eyes. Fluticasone propionate belongs to the class of corticosteroids that works by acting inside cells of the nasal lining. It stops the release of certain chemicals in the body that cause inflammatory reactions, thereby providing relief from sneezing, runny or blocked nose, and sinus discomfort. Azelastine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness. Together Combinase AQ Nasal Spray 70 mdi relieves allergic symptoms, including seasonal allergies, and reduces inflammation of nasal passage.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Combinase AQ Nasal Spray 70 mdi or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Combinase AQ Nasal Spray 70 mdi. Combinase AQ Nasal Spray 70 mdi is not recommended for children below 6 years of age. If you experience any changes in vision, tiredness, nausea, vomiting, light-headedness, chills, fever, body pains, sores, redness or white patches in the mouth or throat, runny nose, severe nosebleeds, or increased drowsiness, stop taking Combinase AQ Nasal Spray 70 mdi and consult a doctor immediately. Avoid contact with people who have infections or who are sick as Combinase AQ Nasal Spray 70 mdi may weaken the immune system causing infections easily. If you have chickenpox, measles, tuberculosis, surgery or injury on the nose, glaucoma, cataracts, herpes infection of the eyes, ulcers or sores inside the nose, inform your doctor before taking Combinase AQ Nasal Spray 70 mdi.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Combinase AQ Nasal Spray 70 mdi:
Co-administration of Combinase AQ Nasal Spray 70 mdi with Mifepristone may make Combinase AQ Nasal Spray 70 mdi less effective as a therapy.

How to manage the interaction:
Taking Combinase AQ Nasal Spray 70 mdi with Mifepristone is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Combinase AQ Nasal Spray 70 mdi:
Taking Ceritinib together with Combinase AQ Nasal Spray 70 mdi may increase the blood levels of Combinase AQ Nasal Spray 70 mdi.

How to manage the interaction:
If you are supposed to take Combinase AQ Nasal Spray 70 mdi and Ceritinib together, your doctor may adjust the dose or monitor you more frequently to use both medications safely. However, if you experience side effects such as high blood pressure, swelling, muscle weakness, acne, depression, thinning skin, easy bruising, stretch marks, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, contact a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Combinase AQ Nasal Spray 70 mdi:
Indinavir may increase the absorption of Combinase AQ Nasal Spray 70 mdi into the bloodstream and increase the risk of side effects.

How to manage the interaction:
If you are supposed to take Combinase AQ Nasal Spray 70 mdi and Indinavir together, your doctor may adjust the dose or monitor you more frequently to use both medications safely. However, if you experience side effects such as weight gain, high blood pressure, swelling, muscle weakness, acne, depression, thinning skin, easy bruising, stretch marks, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, contact your doctor.
How does the drug interact with Combinase AQ Nasal Spray 70 mdi:
Co-administration of Combinase AQ Nasal Spray 70 mdi and Ritonavir may increase the blood levels of Combinase AQ Nasal Spray 70 mdi.

How to manage the interaction:
If you are supposed to take Combinase AQ Nasal Spray 70 mdi and Ritonavir together, your doctor may adjust the dose or monitor you more frequently to use both medications safely. However, if you experience side effects such as palpitations, swelling, high blood sugar, muscle weakness, acne, depression, thinning skin, easy bruising, stretch marks, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, contact a doctor. Do not discontinue the medication without consulting a doctor.
FluticasoneMibefradil
Severe
How does the drug interact with Combinase AQ Nasal Spray 70 mdi:
Co-administration of Mibefradil may significantly increase the absorption of Combinase AQ Nasal Spray 70 mdi into the bloodstream.

How to manage the interaction:
Taking Combinase AQ Nasal Spray 70 mdi with Mibefradil together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - swelling, weight gain, high blood pressure, high blood sugar, weak muscles, feeling down, acne, thinning skin, easy bruising, irregular periods, too much facial or body hair, unusual fat distribution, infection, injury, or a bad asthma attack - make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
FluticasoneDelavirdine
Severe
How does the drug interact with Combinase AQ Nasal Spray 70 mdi:
Co-administration of Delavirdine and Combinase AQ Nasal Spray 70 mdi may significantly increase the absorption of Combinase AQ Nasal Spray 70 mdi into the bloodstream.

How to manage the interaction:
Co-administration of Delavirdine and Combinase AQ Nasal Spray 70 mdi can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like swelling, weight gain, high blood pressure, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Combinase AQ Nasal Spray 70 mdi:
Co-administration of Combinase AQ Nasal Spray 70 mdi with Voriconazole may increase the absorption of Combinase AQ Nasal Spray 70 mdi into the bloodstream and increase the risk of side effects.

How to manage the interaction:
Although Combinase AQ Nasal Spray 70 mdi and Voriconazole can cause an interaction, they can be taken if prescribed by a doctor. However, if you experience swelling, muscle weakness, excessive growth of facial or body hair contact a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Combinase AQ Nasal Spray 70 mdi:
Co-administration of Cladribine with Combinase AQ Nasal Spray 70 mdi can increase the risk of developing serious infections.

How to manage the interaction:
Although taking Combinase AQ Nasal Spray 70 mdi and Cladribine together can evidently cause an interaction, it can be taken if a doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Combinase AQ Nasal Spray 70 mdi:
Co-administration of Combinase AQ Nasal Spray 70 mdi with posaconazole may increase the level of Combinase AQ Nasal Spray 70 mdi in the blood and increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Combinase AQ Nasal Spray 70 mdi and posaconazole, they can be taken together if prescribed by a doctor. However, if you experience muscle weakness, acne, thinning skin, easy bruising, stretch marks, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, contact a doctor. Do not discontinue the medication without consulting a doctor.
FluticasoneConivaptan
Severe
How does the drug interact with Combinase AQ Nasal Spray 70 mdi:
When Conivaptan is taken with Combinase AQ Nasal Spray 70 mdi, it can make Conivaptan break down faster in the body.

How to manage the interaction:
Co-administration of Conivaptan and Combinase AQ Nasal Spray 70 mdi can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like swelling, weight gain, high blood pressure, high blood glucose, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Add ginger to foods or tea as it contains some anti-inflammatory compounds that can relax membranes in the airways and reduce cough, irritation and swelling in nasal passages.
  • Staying hydrated is vital for those with a cough or cold. Drink liquids at room temperature to get relief from a runny nose, cough, and sneezing.
  • The immune system is affected by stress and raises the risk of being sick. Do meditation, deep breathing, regular exercise and try progressive muscle relaxation techniques to get relief from stress.
  • It is advised to avoid contact with known allergens (allergy-causing agents) such as pollen, dust, etc. Certain food items are known to cause allergies to you.
  • Maintain personal hygiene and keep your surroundings clean.

Habit Forming

No

Therapeutic Class

ANTIALLERGIC

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Combinase AQ Nasal Spray 70 mdi contains Fluticasone propionate and Azelastine. Fluticasone propionate is a corticosteroid that works by acting inside cells of the nasal lining and stops the release of certain chemicals in the body that cause inflammatory reactions. Thereby, provides relief from sneezing, runny or blocked nose and sinus discomfort. Azelastine is an antihistamine (anti-allergic drug) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness.

You are recommended to avoid taking grapefruit juice with Combinase AQ Nasal Spray 70 mdi as they may lead to adrenal insufficiency and Cushing’s syndrome.

No, you are not recommended to consume alcohol with Combinase AQ Nasal Spray 70 mdi as it may cause increased drowsiness, dizziness, impairment of judgement and thinking. However, please consult a doctor before consuming alcohol with Combinase AQ Nasal Spray 70 mdi.

Combinase AQ Nasal Spray 70 mdi is not recommended for children below 6 years as the safety and effectiveness were not established. However, please consult a doctor before using Combinase AQ Nasal Spray 70 mdi in children.

Yes, Combinase AQ Nasal Spray 70 mdi may cause drowsiness in some people, especially in people consuming alcohol with Combinase AQ Nasal Spray 70 mdi. It is not necessary for everyone taking Combinase AQ Nasal Spray 70 mdi to experience this side effect. Therefore, avoid driving if you feel drowsy after taking Combinase AQ Nasal Spray 70 mdi.

You are not recommended to take more than the prescribed dose of Combinase AQ Nasal Spray 70 mdi or for a prolonged time as it may cause adverse effects such as changes in body fat (especially in the back, waist, neck and face), easy bruising, skin thinning, increased facial hair or acne, loss of interest in sex, impotence or menstrual problems. However, if you experience any of these symptoms while taking Combinase AQ Nasal Spray 70 mdi, please consult a doctor immediately.

No, Combinase AQ Nasal Spray 70 mdi is not used to treat asthma attacks. Combinase AQ Nasal Spray 70 mdi is used to prevent allergic symptoms that can cause asthma. Therefore, it is recommended to carry a rescue inhaler always to treat asthma attacks.

No, you are not recommended to stop taking Combinase AQ Nasal Spray 70 mdi without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Combinase AQ Nasal Spray 70 mdi for as long as your doctor has prescribed it, and if you experience any difficulty while taking Combinase AQ Nasal Spray 70 mdi, please consult your doctor.

You should avoid taking Combinase AQ Nasal Spray 70 mdi and consult a doctor before using Combinase AQ Nasal Spray 70 mdi if you have had any recent nose problems (like nose bleed, nose injury, nose ulcers, or nose surgery), infections like tuberculosis (TB), eye problems like herpes eye infection, glaucoma, or cataracts.

Drug-Drug Interactions Checker List

  • DULOXETINE
  • ESCITALOPRAM
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  • RITONAVIR
  • KETOCONAZOLE
  • FLUCONAZOLE
  • ITRACONAZOLE
  • CETIRIZINE

Special Advise

Certain blood tests are recommended while taking Combinase AQ Nasal Spray 70 mdi to monitor serum cortisol levels as Combinase AQ Nasal Spray 70 mdi may increase these levels.

Disease/Condition Glossary

Allergy: It is a condition that occurs when the immune system reacts to a foreign substance that is typically not harmful to your body. These foreign substances are known as ‘allergens.’ Allergic condition varies from person to person. Some might be allergic to certain foods and seasonal allergies like hay fever, pollen, or pet dander. One of the main symptoms of allergy is cough, and it acts as a reflex action in the throat when there is any mucus or foreign irritant entry into the respiratory system.

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