apollo
0
Written By ,
Reviewed By Sunny S , MBBS
Non returnable*
COD available

Online payment accepted

rxMedicinePrescription drug

Whats That

tooltip

Manufacturer/Marketer :

Scott Edil Pharmacia Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Combipain Tablet

Combipain Tablet belongs to a class of painkillers called non-steroidal anti-inflammatory drugs (NSAIDs). It relieves symptoms of muscle pain, arthritis pain, dysmenorrhea (painful periods or menstrual cramps), and dental pain and reduces fever. Pain can be temporary (acute) or long-lasting (chronic). Acute pain is for a short time caused by damage to the tissues of the muscle, bone, or other organs. In contrast, chronic pain lasts for a long duration and is caused due to pathologies like nerve damage, osteoarthritis etc. Besides this, it is also useful for dental pain, which can occur due to damage to the tooth nerve, infection, decay, extraction or injury.

Combipain Tablet is composed of two medicines, namely Ibuprofen and Paracetamol. Ibuprofen is known to have an analgesic and anti-inflammatory effect for reducing mild to moderate pain. It works by blocking the effect of a chemical known as prostaglandin, responsible for inducing pain and inflammation in our body. Paracetamol acts as a mild analgesic and antipyretic (fever reducer). It lowers the elevated body temperature and mild pain by inhibiting the synthesis of a chemical messenger (prostaglandin) and promoting heat loss (through sweating) that helps reset the hypothalamic thermostat. Together, these two medicines help reduce mild to moderate pain in a shorter duration.

Combipain Tablet is available in both oral tablet and syrup dosage forms. You should take the syrup form of Combipain Tablet with food or as your doctor advises. The tablet form of Combipain Tablet should be swallowed whole with a glass of water. Do not crush, chew or break it. Do not take Combipain Tablet if your pain lasts more than ten days or your fever lasts more than three days. Do not take a double dose if you missed one dose. Like all medicines, Combipain Tablet may cause side effects, although not everybody gets them. Stop taking this medicine if you experience symptoms like the tightness of the chest, breathing difficulties, fever, skin rashes, increased heart rate and or in case of any signs of hypersensitivity.

Do not take Combipain Tablet if you are allergic to painkillers like aspirin, ibuprofen, naproxen, or diclofenac. It is not recommended for use in children, people with liver disease, heart disease or gastric ulcers/bleeding problems. Combipain Tablet may be associated with a small increase in the risk of heart attack (myocardial infarction). Avoid consumption of alcohol as it may damage your liver and cause increased side effects on taking this drug. Consult your doctor if your pain, inflammation, and fever symptoms do not disappear even after ten days.

Uses of Combipain Tablet

Muscle pain, Arthritis pain, Headache, Migraine, Backache, Dental pain, Fever.

Directions for Use

Tablet: Use Combipain Tablet as prescribed by your doctor. Take Combipain Tablet with food to avoid stomach upset and swallow the whole tablet with a glass of water. Do not break, crush or chew it.Syrup: Shake the bottle well before use. Check the label for directions and take Combipain Tablet in doses as prescribed by your doctor with the help of a measuring cup.

Medicinal Benefits

Combipain Tablet comprises Ibuprofen and Paracetamol primarily used to treat mild to moderate pain. Combipain Tablet is prescribed mainly to treat pain and relieve discomfort caused by conditions like tooth pain, arthritis, period pain and other types of short-term pains. It helps treat pain by blocking the chemical messenger (prostaglandin) in the brain responsible for causing pain. Ibuprofen works by blocking the effect of a chemical known as prostaglandin, responsible for inducing pain and inflammation in our body. On the other hand, Paracetamol lowers the elevated body temperature and mild pain by inhibiting the synthesis of prostaglandin by promoting heat loss (through sweating) that helps reset the hypothalamic thermostat. Paracetamol has the advantage of producing less gastric irritation than other painkillers like aspirin.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Combipain Tablet

  • Nausea
  • Vomiting
  • Diarrhoea
  • Flatulence
  • Constipation
  • Thrombocytopenia (low level of platelets)
  • Neutropenia/leucopenia (low white blood cells)
  • Skin rashes (urticaria)
  • Peptic ulcers
  • Gastrointestinal bleeding
  • Dyspepsia
  • Abdominal pain
  • Colitis (inflammation of the intestine)
  • Inflammatory bowel disorder

Drug Warnings

Caution is advised in people with underlying sensitivity to aspirin and other pain killers. Combipain Tablet is contraindicated in children below 12 years of age under 40 kg of weight. If treatment is required for more than three days, consult your doctor. Combipain Tablet should be taken with caution if you have an allergy to paracetamol, ibuprofen, aspirin, or other pain killers, highly sensitive reactions (asthma, lip/face/throat swelling), existing stomach ulcer or bleeding associated pain killers, blood clotting disorder, heart diseases (like congestive heart failure), kidney disease, peptic ulcer, another active bleeding (like brain stroke bleeding), and severe dehydration (due to vomiting, diarrhoea). Liver damage might occur if taken for a longer duration as it contains paracetamol. The skin should be closely monitored as skin allergic reactions like Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) have been reported with Combipain Tablet . Blood pressure and cardiovascular (heart) status should be monitored closely during the treatment with Combipain Tablet , especially in people affected with high blood pressure and who have a history of heart failure.

Drug-Drug Interactions

verifiedApollotooltip
IbuprofenKetorolac
Critical
IbuprofenMeloxicam
Critical

Drug-Drug Interactions

Login/Sign Up

IbuprofenKetorolac
Critical
How does the drug interact with Combipain Tablet:
Taking Ketorolac and Combipain Tablet can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding and ulceration.

How to manage the interaction:
Taking Ketorolac and Combipain Tablet together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, red or black, dark stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenMeloxicam
Critical
How does the drug interact with Combipain Tablet:
Combining Meloxicam and Combipain Tablet can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
Taking Meloxicam and Combipain Tablet together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, red or black, dark stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenVorapaxar
Severe
How does the drug interact with Combipain Tablet:
The combined use of Vorapaxar and Combipain Tablet can increase the risk of bleeding, including severe and sometimes haemorrhage.

How to manage the interaction:
Co-administration of Vorapaxar and Combipain Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache; and weakness. consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenMethotrexate
Severe
How does the drug interact with Combipain Tablet:
Coadministration of methotrexate with Combipain Tablet can increase the effect and side effects of methotrexate.

How to manage the interaction:
Although there is a possible interaction between methotrexate and Combipain Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth sores or ulcers, nausea, vomiting, diarrhea, rash, appetite loss, joint pain or swelling, yellowing of the skin or eyes, dark urine, shortness of breath, a dry cough, pallor, dizziness or fainting, unusual bruising or bleeding, seizures, infection; as well as flu-like signs (fever, chills, body pains, sore throat, and weakening of the muscles), consult a doctor immediately. Do not stop using medications without a doctor's advice.
IbuprofenCelecoxib
Severe
How does the drug interact with Combipain Tablet:
Coadministration of Celecoxib and Combipain Tablet can increase the risk of gastrointestinal bleeding and ulcers.

How to manage the interaction:
Although there is a interaction between Combipain Tablet and Celecoxib, but it can be taken if your doctor has advised it. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Do not discontinue any medication without consulting a doctor.
IbuprofenPrasugrel
Severe
How does the drug interact with Combipain Tablet:
Co-administration of Prasugrel and Combipain Tablet can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Prasugrel and Combipain Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenEnoxaparin
Severe
How does the drug interact with Combipain Tablet:
The combined use of Enoxaparin and Combipain Tablet can increase the risk of bleeding problems.

How to manage the interaction:
Co-administration of Enoxaparin and Combipain Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenPhenylbutazone
Severe
How does the drug interact with Combipain Tablet:
The combined use of Phenylbutazone and Combipain Tablet can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
Co-administration of Phenylbutazone and Combipain Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenMetrizamide
Severe
How does the drug interact with Combipain Tablet:
The combined use of Metrizamide and Combipain Tablet can cause kidney damage.

How to manage the interaction:
Co-administration of Metrizamide and Combipain Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, irregular heart rhythm, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenTinzaparin
Severe
How does the drug interact with Combipain Tablet:
The combined use of Tinzaparin and Combipain Tablet can increase the risk of bleeding complications.

How to manage the interaction:
Co-administration of Tinzaparin and Combipain Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulphate, vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help reduce inflammation in the tissue.
  • Please do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do low-impact aerobic exercises like walking on the treadmill, bike riding and swimming. You can also strengthen your muscles by lifting light weights.
  • In the chronic condition of arthritis or joint pain, try to include fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that minimum level of chemical called cytokines, which ramp up inflammation.
  • Your sitting posture is important, especially when you have pain and inflammation. Try to sit as little as possible and only for a short time. Long-term immobility is harmful in conditions like arthritis. Use back support like a rolled-up towel to minimise pain at the back of your spine curve. Keep your knees and hips at a right angle. Besides this, you can also use a footrest if required.

Habit Forming

No

Therapeutic Class

ANALGESIC AND ANTIPYRETIC AGENT

Combipain Tablet Substitute

Substitutes safety advice
  • Combiflam Tablet 20's

    by Others

    2.50per tablet
  • Flexon Tablet 15's

    by Others

    2.04per tablet
  • Ibugesic Plus Tablet 20's

    by AYUR

    1.65per tablet
  • Brufen P Tablet 20's

    by Others

    1.60per tablet
  • Brustan Tablet 10's

    by Others

    1.54per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

Login/Sign Up

FAQs

Combipain Tablet is comprised of two medications, Ibuprofen and Paracetamol. Combipain Tablet  has analgesic and anti-inflammatory properties that help relieve mild to moderate pain. Combipain Tablet functions by inhibiting the production of specific chemical messengers that induce fever, discomfort, and inflammation (redness and swelling).

No, it is not advisable to take Combipain Tablet with depression medication. Please inform your doctor if you are taking depression medicine before starting Combipain Tablet .

Yes, Combipain Tablet is a short term medication and if you feel better you can stop taking Combipain Tablet , but only after consulting your doctor.

Combipain Tablet is known to be contra-indicated in patients with allergy to painkillers (NSAIDs) or any of the components or excipients of this medicine. Its use should also be avoided in patients with history of stomach ulcer and kidney/liver disease.

Yes, Combipain Tablet is known to cause dizziness. If you feel dizzy, please take rest and also avoid driving while you take Combipain Tablet as it can be harmful.

No, Combipain Tablet is not indicated for stomach pain. Also, If you have stomach pain post ingestion it may be a sign of stomach ulcer, or gastric bleeding. Do not take Combipain Tablet in this condition. It is better to inform your doctor in case of stomach pain post ingestion of this medication.

It depends on whether your cough and cold pills contain ibuprofen and paracetamol or not. If it contains these two medicines, do not take it. It may lead to overdosage, thereby producing unpleasant side effects. Consult your doctor before taking it in such cases.

Combipain Tablet is known to cause stomach upset in some cases. So, please take Combipain Tablet with a meal or a glass of milk to avoid upset stomach.

No, Combipain Tablet should not be taken as a long-term medication as it may lead to stomach ulcers/bleeding and kidney problems. For best results of Combipain Tablet , please take it in doses and duration mentioned by your doctor.

Drug-Drug Interactions Checker List

  • WARFARIN
  • TICLOPIDINE
  • METHOTREXATE
  • METOCLOPRAMIDE
  • DOMPERIDONE
  • FUROSEMIDE
  • PREDNISONE
  • CIPROFLOXACIN
  • THEOPHYLLINE
  • EPHEDRINE
  • CHOLESTYRAMINE
  • DULOXETINE

Special Advise

  • Let your doctor know if you are suffering from stomach ulcers as the Combipain Tablet may enhance the same.

Disease/Condition Glossary

Pain: Pain can be short-term (acute) or long-term (chronic). Acute pain is for a short time caused by damage to the tissues of the muscle, bone, or organs. In contrast, chronic pain lasts for a longer duration. It is caused due to pathologies like nerve damage, Osteoarthritis, and dental pain due to damage to the tooth nerve, infection, decay, extraction, or injury. Many women have painful periods known as dysmenorrhea, most often menstrual cramps. On the other hand, Osteoarthritis is a degenerative disease that results in chronic pain in joints (especially the knee) and stiffness making daily tasks difficult.

Fever: Fever is not a disease but a sign that your body is trying to fight an infection or illness in which your body's immune system gets activated to fight infections caused by bacteria or viruses. A normal temperature is around 98.6 F but may vary from person to person. Fever is caused due to the 'pyrogen' released by the hypothalamus part of the brain. This pyrogen causes heat-generating effects to match a new higher temperature set point to fight infection.

whatsapp Floating Button