Combisaf Tablet 1's belongs to the class of 'antibiotics', primarily used to treat vaginal infections, such as bacterial vaginosis (BV), candidiasis, trichomoniasis, and mixed infections with chlamydia and Neisseria. Bacterial vaginosis is caused by the change in the normal balance of vaginal bacteria. Vaginal yeast infection or Candidiasis is the infection of the vagina and tissues at the opening of the vagina (vulva). Trichomoniasis is a sexually transmitted infection caused by a parasite. Chlamydia is a sexually transmitted infection caused by bacteria. Symptoms of a vaginal infection include itching, odour and abnormal vaginal discharge.

Combisaf Tablet 1's comprises three medicines: Azithromycin (antibiotic), Fluconazole (antifungal), and Secnidazole (antibiotic). Azithromycin belongs to the class of 'macrolide antibiotics'. It works by inhibiting bacterial protein synthesis, which inhibits bacterial growth. Fluconazole belongs to the class of 'azole antifungal' agents. It stops the growth of fungi by causing damage and leakage to the fungal cell membrane. Secnidazole is an antibiotic that belongs to the class of 'amoebicides'. It works by stopping the growth of infection-causing bacteria.

Use Combisaf Tablet 1's as prescribed by the doctor. Common side effects of Combisaf Tablet 1's include taste changes, vomiting, headache, dizziness, stomach pain, nausea, indigestion, diarrhoea, and loss of appetite. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Inform your doctor if you are allergic to Combisaf Tablet 1's or any of its components. It is essential to tell your doctor if you use any other azole antifungal agents before using Combisaf Tablet 1's. Let your doctor know if you have any liver, kidney, gastrointestinal diseases (diarrhoea and colitis, inflammation of the colon), allergic conditions, ulcers or blisters, and urination problems. Pregnant and breastfeeding women should consult their doctor before starting Combisaf Tablet 1's. It is advised to avoid alcohol intake while using Combisaf Tablet 1's to prevent any undesirable effects.

Combisaf Tablet 1's is used to treat vaginal infections, such as bacterial vaginosis (BV), candidiasis, trichomoniasis, and mixed infections with chlamydia and Neisseria. It comprises three medicines: Azithromycin, Fluconazole, and Secnidazole. Azithromycin is an antibiotic that works by inhibiting bacterial protein synthesis, which further inhibits bacterial growth. Fluconazole is an antifungal drug that stops fungi growth by causing damage and leakage to the fungal cell membrane. Secnidazole is an antibiotic works by stopping the growth of infection-causing bacteria. It effectively treats vaginal infection (bacterial vaginosis).

• Taste changes
• Vomiting
• Headache
• Dizziness
• Stomach pain
• Nausea
• Indigestion
• Diarrhoea
• Loss of appetite 

Please inform your doctor if you use any prescription, non-prescription medicines, including vitamin and herbal supplements before using Combisaf Tablet 1's. Do not use Combisaf Tablet 1's if you are allergic to Combisaf Tablet 1's or any of its components. Let your doctor know if you have any liver, kidney, gastrointestinal diseases (diarrhea and colitis, an inflammation of the colon), allergic conditions, ulcers or blisters, and urination problems. Combisaf Tablet 1's is not recommended in case of severe renal impairment. It is advised to use Combisaf Tablet 1's under your doctor's supervision if you use other azole antifungal medicines. It is better to avoid Combisaf Tablet 1's during the first trimester of pregnancy. Combisaf Tablet 1's should be used with caution and only under a doctor's advice if you are a nursing mother. Do not drive or operate machinery if you experience dizziness or other side effects that may affect your mental ability to drive. Avoid alcohol consumption along with Combisaf Tablet 1's to avoid undesirable effects like flushing, increased heartbeat, nausea, thirst, chest pain, and low blood pressure. Do not take any antacids containing magnesium or aluminum for up to two hours after using Combisaf Tablet 1's.

Drug-Drug Interaction: Combisaf Tablet 1's may interact with magnesium or aluminium-containing antacids, heart-related medicines (digoxin), insomnia-treating drugs (triazolam), immunosuppressants (cyclosporine, tacrolimus), fits medicines (carbamazepine, phenytoin), antibiotics (rifampicin, rifabutin), respiratory drugs (theophylline), anti-allergy drugs (astemizole), and blood thinners.

Drug-Food Interaction: Avoid alcohol intake while using Combisaf Tablet 1's.

Drug-Disease Interaction: Before taking Combisaf Tablet 1's, let your doctor know if have any liver, kidney, gastrointestinal diseases (diarrhea and colitis, an inflammation of the colon), allergic conditions, ulcers or blisters, and urination problems.

• DIGOXIN
• TRIAZOLAM
• CYCLOSPORINE
• TACROLIMUS
• CARBAMAZEPINE
• PHENYTOIN
• RIFAMPICIN
• RIFABUTIN
• THEOPHYLLINE
• ASTEMIZOLE

• Avoid frequent douching to maintain the natural moisture in the vagina.
• Use mild soap while taking baths and prefer warm baths.
• Avoid harsh products on your skin.
• Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
• Avoid or limit the intake of alcohol and caffeine.

It is advised to reach out to your doctor if the infection symptoms persist or worsen after two weeks of treatment. 

Bacterial vaginosis: It is a type of vaginal infection caused by the change in the normal balance of vaginal bacteria.

Vaginal yeast infection or Candidiasis is the infection of the vagina and tissues at the opening of the vagina (vulva). 

Trichomoniasis is a sexually transmitted infection caused by a parasite. Symptoms of a vaginal infection include itching, odor, and abnormal vaginal discharge.