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Written By Divya L , PharmaD
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
COD available

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Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

INHALATION

Return Policy :

Not Returnable

Expires on or after :

About COMBITIDE 50MG INHALER

COMBITIDE 50MG INHALER is a respiratory medication primarily used to treat and prevent respiratory disorders like asthma attacks and chronic obstructive pulmonary diseases (COPD). Asthma is a breathing problem in which airways narrow, swell, and produce extra mucus, leading to difficulty breathing. COPD is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of your bronchial tubes).

COMBITIDE 50MG INHALER is a combination of two medicines, namely: Salmeterol (bronchodilator) and Fluticasone. Salmeterol is a long-acting bronchodilator that relaxes the muscles in the airways and increases airflow to the lungs. It makes breathing easier by widening the airways. Fluticasone belongs to the class of corticosteroids. It acts by blocking prostaglandins' production (chemical messengers) that cause inflammation (swelling) of the airways.

Your doctor will advise on how often you take COMBITIDE 50MG INHALER based on your medical condition. The common side effects of COMBITIDE 50MG INHALER include nausea, vomiting, respiratory tract infection, headache, sore throat, cough, bone, muscle or joint pain, increased heart rate, chills, black or tarry stools, and noisy breathing. Most of these side effects of COMBITIDE 50MG INHALER do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Brief your medical history to the doctor if you have heart, liver, kidney diseases, hypokalaemia (low potassium levels in the blood), hyperadrenocorticism (high levels of cortisol), eye disorders like cataract and glaucoma, seizure (fits), osteoporosis (weak and brittle bones), and diabetes before taking COMBITIDE 50MG INHALER. Therapy with nasal or inhaled corticosteroids like Fluticasone should be cautiously administered in patients with a fungal, bacterial, parasitic, or viral infection and tuberculosis since there are chances of developing a secondary infection. Please check with your doctor if you are pregnant, currently breastfeeding, or taking any other prescribed or non-prescribed medicines.

Uses of COMBITIDE 50MG INHALER

Chronic Obstructive Pulmonary Disease (COPD), Bronchitis, Asthma, and Emphysema.

Directions for Use

Inhaler: Hold the inhaler with the mouthpiece facing downwards. Form a tight seal by placing your lips around the mouthpiece. Start breathing slowly with your mouth and push down the inhaler once. Remove the inhaler and breathe normally.Rotacap/Transcap:Rotacap/Transcap is a capsule with powdered medication which is placed in Rotahaler. It is for inhalation only. Do not swallow the capsule. Rotahaler/Transhaler is a plastic inhalation device that releases the medication when you breathe. The capsule should be placed at the base of the rotahaler/transhaler and completely twist the mouthpiece until you hear a click sound. Then, breathe in through the mouthpiece deeply and hold your breath for 10 seconds. Remove the device and breathe out normally.Respicap/Instacaps: Please read the instruction leaflet before usage and use in the dose and duration suggested by your doctor.Autohaler: Autohaler is a breath-activated device that releases the medication when you inhale. Shake the autohaler well before using it. Hold it upright and push the lever up. Place the mouthpiece in your mouth and seal your lips around it. Breathe in slowly and deeply to release the medication from the device. Hold your breath for 10 seconds and breathe out normally. Push the lever down and replace the cap.Inhalation Capsule: The capsule is meant for inhalation only; do not swallow the capsule. Check the instructions leaflet before use. Place it at the base of the inhaler and twist the mouthpiece until you hear a click sound. Breathe deeply through the mouthpiece and hold your breath for 10 seconds.Oral inhalation (Powder): Check the label for directions to use. Inhale the powder by mouth using an inhaler.Rotadisk: Rotadisk is a silver-coloured aluminium foil disk that contains four blisters to place the medication. The medicine is to be inhaled through the mouth from the Rotadisk using a plastic device called Diskhaler.

Medicinal Benefits

COMBITIDE 50MG INHALER is used to treat and prevent respiratory disorders like asthma attacks and chronic obstructive pulmonary diseases (COPD). COMBITIDE 50MG INHALER improves pulmonary function and effectively treats and prevents the worsening of emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of your bronchial tubes). COMBITIDE 50MG INHALER is a combination of Salmeterol (bronchodilator) and Fluticasone (corticosteroid). Salmeterol relaxes the muscles in the airways and increases airflow to the lungs. It makes breathing easier by widening the airways. Fluticasone acts by blocking prostaglandins' production (chemical messengers) that cause inflammation (swelling) of the airways. Fluticasone has potent vasoconstrictive (narrowing of the blood vessels) and anti-inflammatory activity.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not stop taking this medicine of your own unless advised by your doctor. Before taking COMBITIDE 50MG INHALER, let your doctor know if have a history of heart, liver, kidney diseases, hyperadrenocorticism (high levels of cortisol), eye disorders like cataracts and glaucoma, seizure (fits), osteoporosis (weak and brittle bones), and diabetes. COMBITIDE 50MG INHALER causes hypokalemia (low potassium levels in the blood), therefore should be used with caution in patients with hypokalaemia to prevent any cardiovascular effects.  Special precautions should be taken in patients with a fungal, bacterial, parasitic, or viral infection and tuberculosis since nasal or inhaled corticosteroids like Fluticasone can cause secondary infections. COMBITIDE 50MG INHALER can cause a rise in blood glucose levels. Hence monitor your blood glucose levels regularly if you are diabetic. Please let your doctor know if you plan to become pregnant or are already pregnant and a lactating mother. Do not drive or operate machinery if you experience drowsiness and increased/uneven heart rate while using COMBITIDE 50MG INHALER. Avoid drinking alcohol while taking this medicine as it can worsen your side effects.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Combitide 50 Inhaler:
Co-administration of Combitide 50 Inhaler with Mifepristone may make Combitide 50 Inhaler less effective as a therapy.

How to manage the interaction:
Taking Combitide 50 Inhaler with Mifepristone is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Combitide 50 Inhaler:
When Ribociclib is taken with Combitide 50 Inhaler, it can increase the chance of a serious abnormal heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
There may be a possibility of interaction between Combitide 50 Inhaler and Ribociclib, but it can be taken if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
SalmeterolDelavirdine
Severe
How does the drug interact with Combitide 50 Inhaler:
The combined use of Delavirdine and Combitide 50 Inhaler can increase the risk of irregular heart rhythm.

How to manage the interaction:
Co-administration of Combitide 50 Inhaler with Delavirdine can result in an interaction, but it can be taken if a doctor has advised it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
How does the drug interact with Combitide 50 Inhaler:
Taking Voriconazole may significantly increase the blood levels of Combitide 50 Inhaler. High blood levels of Combitide 50 Inhaler can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although taking Voriconazole and Combitide 50 Inhaler together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience dizziness, shortness of breath, or heart palpitations (irregular heartbeat), contact a doctor right away. Do not discontinue any medications without consulting a doctor.
SalmeterolTelithromycin
Severe
How does the drug interact with Combitide 50 Inhaler:
Telithromycin may significantly increase the blood levels of Combitide 50 Inhaler. High blood levels of Combitide 50 Inhaler can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction between Combitide 50 Inhaler and Telithromycin, you can take these medicines together if prescribed by a doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
SalmeterolFosamprenavir
Severe
How does the drug interact with Combitide 50 Inhaler:
The combined use of Fosamprenavir and Combitide 50 Inhaler can increase the risk of irregular heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between Combitide 50 Inhaler and Fosamprenavir, but it can be taken if prescribed by a doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
SalmeterolNelfinavir
Severe
How does the drug interact with Combitide 50 Inhaler:
Nelfinavir may significantly increase the blood levels of Combitide 50 Inhaler. High blood levels of Combitide 50 Inhaler can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Co-administration of Combitide 50 Inhaler with Nelfinavir can result in an interaction, but it can be taken if your doctor has advised it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
SalmeterolCocaine
Severe
How does the drug interact with Combitide 50 Inhaler:
Using Combitide 50 Inhaler together with cocaine nasal may occasionally cause irregular heart rhythm.

How to manage the interaction:
Co-administration of Combitide 50 Inhaler with Cocaine can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
SalmeterolPenbutolol
Severe
How does the drug interact with Combitide 50 Inhaler:
The combined use of Penbutolol and Combitide 50 Inhaler can decrease the effect of both Combitide 50 Inhaler and Penbutolol. It may also increase the risk of severe asthma attacks or breathing problems.

How to manage the interaction:
Co-administration of Combitide 50 Inhaler with Penbutolol can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
SalmeterolBoceprevir
Severe
How does the drug interact with Combitide 50 Inhaler:
Co-administration of Boceprevir and Combitide 50 Inhaler together can increase the irregular heart rhythm.

How to manage the interaction:
Although taking Combitide 50 Inhaler and Boceprevir together can cause an interaction, it can be taken if a doctor has suggested it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals. Do not use other over the counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take COMBITIDE 50MG INHALER.
  • Know your triggers like allergens, such as pollen, dust, and food items that make your asthma severe.
  • Quit smoking and avoid passive smoking. Smoking also reduces the effectiveness of the medicine.
  • Eat a healthy diet and exercise regularly to strengthen your breathing muscles and boost your immune system.
  • Learning breathing exercises will help you move more air in and out of your lungs.

Habit Forming

No

Therapeutic Class

RESPIRATORY STIMULANTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Drug-Drug Interactions Checker List

  • FUROSEMIDE
  • BUDESONIDE
  • VILANTEROL
  • FORMOTEROL
  • ALBUTEROL
  • IPRATROPIUM
  • METOPROLOL

Special Advise

  • It is advised to undergo blood examination to keep a check on your potassium levels since COMBITIDE 50MG INHALER can cause low potassium levels in the blood (hypokalaemia).
  • Regularly monitor your blood sugar levels while using COMBITIDE 50MG INHALER since bronchodilators like Salmeterol can cause low blood glucose levels.
  • Consult your diabetologist if you have diabetes before using COMBITIDE 50MG INHALER so that your insulin or other diabetic medication can be adjusted accordingly to maintain your blood sugar levels.

Disease/Condition Glossary

Asthma: It is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty in breathing. The symptoms of asthma include wheezing (whistling sound while breathing), shortness of breath, chest tightness and cough, especially at night. The symptoms of mild persistent asthma may occur more than 2 times in a week and up to 4 nights in a month whereas, in case of severe persistent asthma, the symptoms occur several times every day and most nights. The treatment for asthma includes medication, breathing exercises and self-care.

Chronic obstructive pulmonary disease (COPD): It is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes). The major cause of COPD is smoking tobacco. Also, long-term exposure to fumes and chemicals may also lead to COPD. The symptoms include chronic cough, shortness of breath or wheezing (whistle sound while breathing).

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