apollo
0

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
Insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
  1. Home
  2. Medicine

  3. Combunex 800 Tablet 10's

Combunex 800 Tablet 10's, Pack of 10 TABLETS
Combunex 800 Tablet 10's, Pack of 10 TABLETS
Combunex 800 Tablet 10's, Pack of 10 TABLETS
Combunex 800 Tablet 10's, Pack of 10 TABLETS
Combunex 800 Tablet 10's, Pack of 10 TABLETS
Not for online sale
Written By ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
Know More
COD available

Online payment accepted

rxMedicinePrescription drug

Whats That

tooltip

Composition :

ETHAMBUTOL-800MG + ISONIAZID-300MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Combunex 800 Tablet

Combunex 800 Tablet belongs to the group of medications called ‘antituberculosis agents’ primarily used in the treatment of tuberculosis (TB). Tuberculosis is an infectious bacterial disease that mainly affects the lungs, but it can also spread to other body parts such as kidneys, brain, spine and bone marrow. Combunex 800 Tablet does not work against infections caused by the virus.

Combunex 800 Tablet contains Isoniazid and Ethambutol. They are bacteriostatic agents (stop the growth of bacteria) and have a similar mode of action. They work by preventing mycolic acid production (an enzyme produced by bacteria) essential for cell wall formation (protective coating). Thereby, bacteria get killed without a cell wall and burst due to disruption in their metabolism.

Take Combunex 800 Tablet exactly as prescribed by the doctor. Combunex 800 Tablet may cause side effects such as weakness, malaise (general discomfort), fatigue (feeling tired), loss of appetite, nausea or vomiting, dark urine, pale stools, jaundice (yellowing of the skin or whites of the eyes) and vision problems. Inform your doctor immediately if any of these side effects persist or get worse.

It is not recommended to take Combunex 800 Tablet if you are allergic to any contents of it. Combunex 800 Tablet is not recommended for patients with severe liver problems and sight problems. Before taking Combunex 800 Tablet , inform your doctor if you have kidney problems, epilepsy (fits), diabetes, alcohol abuse, psychosis, malnourishment, HIV infection, and extra-pulmonary TB (TB infection outside the lungs). Combunex 800 Tablet should be used with caution in pregnant and breastfeeding women. Dose adjustments may be required in children and elderly people. Combunex 800 Tablet may interact with alcohol and increase the risk of liver damage. Combunex 800 Tablet may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

Uses of Combunex 800 Tablet

Tuberculosis

Directions for Use

Take Combunex 800 Tablet on an empty stomach preferably at least one hour before breakfast or snack or after two hours of a meal. or take it as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Combunex 800 Tablet contains Isoniazid and Ethambutol, which is a fixed-dose combination used to treat tuberculosis (TB). Combination therapy reduces the development of drug resistance (reduction in the effectiveness of medication) as the bacteria causing TB develops drug resistance easily when monotherapy is given even for shorter periods. Combunex 800 Tablet helps to reduce the symptoms and control the disease effectively.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

It is advised to get your eyesight checked before taking Combunex 800 Tablet . If you notice any changes in your vision while using this medicine, stop taking this medicine and immediately inform your doctor. In most cases, the vision change is temporary and sight returns to normal. However, it might take a longer time for eyesight to recover in some cases or the change might be permanent. If you develop jaundice (yellowing of the skin and whites of the eyes), loss of appetite, nausea, vomiting, or malaise, inform your doctor immediately, as these effects may be a sign of hepatitis (liver disease). In these cases, the doctor may advise you to undergo liver function tests and provide the necessary treatment.

Drug-Drug Interactions

verifiedApollotooltip
IsoniazidRegorafenib
Critical
IsoniazidLomitapide
Critical

Drug-Drug Interactions

Login/Sign Up

IsoniazidRegorafenib
Critical
How does the drug interact with Combunex 800 Tablet:
When Combunex 800 Tablet is taken with Regorafenib, it can increase the levels of Regorafenib leading to side effects.

How to manage the interaction:
Taking Regorafenib with Combunex 800 Tablet is not recommended, it taken can be taken if prescribed by the doctor.
IsoniazidLomitapide
Critical
How does the drug interact with Combunex 800 Tablet:
When Lomitapide is taken with Combunex 800 Tablet, Combunex 800 Tablet may increase the blood levels of lomitapide which leads to side effects.

How to manage the interaction:
Taking Combunex 800 Tablet with Lomitapide is not recommended but can be taken if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor.
IsoniazidLovastatin
Critical
How does the drug interact with Combunex 800 Tablet:
When Lovastatin is taken with Combunex 800 Tablet, can increase the risk of myopathy (muscles problems), including rhabdomyolysis (a condition that causes your muscles to break down, which leads to muscle death).

How to manage the interaction:
Taking Combunex 800 Tablet with Lovastatin is not recommended but can be taken if a doctor has prescribed it.
EthambutolLomitapide
Severe
How does the drug interact with Combunex 800 Tablet:
Taking Lomitapide and Combunex 800 Tablet together can increase the risk of liver problems.

How to manage the interaction:
Although taking Combunex 800 Tablet and Lomitapide together can cause an interaction, it can be taken if your doctor has suggested it. However, consult a doctor if you experience fever, joint pain or swelling, skin rash, vomiting, abdominal pain, dark urine, or yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.
EthambutolMipomersen
Severe
How does the drug interact with Combunex 800 Tablet:
Coadministration of mipomersen with Combunex 800 Tablet can increase the risk of liver problems.

How to manage the interaction:
Although taking Combunex 800 Tablet and Mipomersen together can cause an interaction, it can be taken if your doctor has suggested it. However, contact your doctor immediately if you experience fever, joint pain or swelling, skin rash, vomiting, abdominal pain, dark urine, or yellowing of the skin or eyes. Do not discontinue any medications without consulting your doctor.
EthambutolKetoconazole
Severe
How does the drug interact with Combunex 800 Tablet:
Taking Ketoconazole with Combunex 800 Tablet can increase the risk of liver problems

How to manage the interaction:
Although there is an interaction, Ketoconazole can be taken with Combunex 800 Tablet if prescribed by the doctor. However, consult the doctor if you experience symptoms such as fever, joint pain or swelling, unusual bleeding or bruising, skin rash, nausea, vomiting, dark urine, skin or eye yellowing. Do not stop using any medications without talking to the doctor.
EthambutolTeriflunomide
Severe
How does the drug interact with Combunex 800 Tablet:
Coadministration of Combunex 800 Tablet with teriflunomide can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Combunex 800 Tablet with Teriflunomide can result in an interaction, but it can be taken if your doctor has advised it. However, contact your doctor if you experience fever, joint pain or swelling, skin rash, vomiting, abdominal pain, dark urine, or yellowing of the skin or eyes. Do not discontinue any medications without consulting your doctor.
EthambutolLeflunomide
Severe
How does the drug interact with Combunex 800 Tablet:
Coadministration of Combunex 800 Tablet with Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although taking Combunex 800 Tablet with Leflunomide can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor immediately if you experience fever, joint pain or swelling, skin rash, vomiting, abdominal pain, dark urine, or yellowing of the skin or eyes. Do not discontinue using any medications without consulting a doctor.
EthambutolVigabatrin
Severe
How does the drug interact with Combunex 800 Tablet:
Co-administration of Vigabatrin with Combunex 800 Tablet may increase the risk of serious side effects associated with vision loss, especially if used together for prolonged periods.

How to manage the interaction:
Co-administration of Combunex 800 Tablet with Vigabatrin can result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
IsoniazidRifabutin
Severe
How does the drug interact with Combunex 800 Tablet:
Co-administration of Rifabutin with Combunex 800 Tablet can increase the risk of liver problems.

How to manage the interaction:
Although taking Rifabutin and Combunex 800 Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, a skin rash or itching, appetite loss, nausea, vomiting, or yellowing of the skin or the whites of your eyes, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Diet & Lifestyle Advise

  • Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.
  • Vitamin C-rich foods such as kiwi, broccoli, and bell pepper help improve the immune system.
  • Avoid processed and fried foods.
  • Stay hydrated. Drink plenty of fluids.
  • Warm ginger tea or warm soup can help in providing relief from cough.
  • Avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, and fish such as tuna, salmon, mackerel, wine, and beer.
  • Quit smoking and avoid alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTI- TUBERCULOSIS

Combunex 800 Tablet Substitute

Substitutes safety advice

Product Substitutes

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

Login/Sign Up

FAQs

Combunex 800 Tablet contains Isoniazid and Ethambutol. They are bacteriostatic agents (stop the growth of bacteria) and have a similar mode of action. They work by preventing mycolic acid production (an enzyme produced by bacteria) essential for cell wall formation (protective coating, which is necessary for bacteria's survival).

It is advised to take Combunex 800 Tablet on an empty stomach. So, you should take this medicine at least 30 minutes before a meal or after 2 hours of taking a meal for better absorption.

You are recommended to avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, fish such as tuna, salmon and mackerel, wine and beer as they may interact with Combunex 800 Tablet and cause adverse effects such as sweating, headache, dizziness, flushing (reddening of the skin) and uneven heartbeat.

Combunex 800 Tablet may cause side-effects such as weakness, malaise (general discomfort), fatigue (feeling tired), loss of appetite, nausea or vomiting, dark urine, pale stools, jaundice (yellowing of the skin or whites of the eyes) and vision problems. Inform your doctor immediately if any of these side-effects persist or get worse.

Combunex 800 Tablet may affect liver function, so it is not prescribed in patients with severe liver problems and alcohol abuse unless clinically needed. Also, do not consume excessive amounts of alcohol while using Combunex 800 Tablet as it may increase the risk of liver damage.

Yes, ethambutol in Combunex 800 Tablet may rarely cause vision problems like blurred/decreased vision, color blindness. Consult your doctor immediately if there is a problem in vision.

Drug-Drug Interactions Checker List

  • ALUMINIUM HYDROXIDE
  • CARBAMAZEPINE
  • PHENYTOIN
  • PRIMIDONE
  • DISULFIRAM
  • RIFAMPICIN
  • PARA-AMINOSALICYLIC ACID
  • DIAZEPAM
  • LEVODOPA
  • ITRACONAZOLE
  • KETOCONAZOLE

Special Advise

  • Patients with kidney problems should undergo kidney function tests before taking Combunex 800 Tablet .
  • Your doctor may monitor liver function and eyesight during the treatment with Combunex 800 Tablet .
  • Please do not stop taking this medicine abruptly as it may lead to withdrawal reactions such as headache, difficulty sleeping, irritability and nervousness.
  • Complete the full course of therapy even if you feel better or your symptoms improve.

Disease/Condition Glossary

Tuberculosis (TB): It is an infectious bacterial disease that affects the lungs, but it could also spread to other body parts such as kidneys, brain, spine, and bone marrow. Tuberculosis is caused by bacteria named Mycobacterium tuberculosis. It is a contagious disease that can spread to others through small droplets released into the air by a person suffering from tuberculosis. Symptoms include a cough that lasts for a few weeks, pain while coughing or normal breathing, unexplained fatigue, fever, night sweats, and loss of appetite, and weight. People who smoke or consume alcohol, and people diagnosed with HIV and immune system problems are more likely at risk of developing active TB.

Have a query?

Buy best Infections & Infestation products by

whatsapp Floating Button