apollo
0

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
Insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
  1. Home
  2. Medicine

  3. Comtrix O 200 mg Tablet 10's

Comtrix O 200 mg Tablet 10's, Pack of 10 IndiaS
Not for online sale
Written By Veda Maddala , M Pharmacy
Reviewed By Sureshvarma D , MPharma
Non returnable*
Know More
COD available

Online payment accepted

rxMedicinePrescription drug

Whats That

tooltip

Composition :

CEFIXIME-200MG + LACTOBACILLUS-60MILLIONS SPORES

Manufacturer/Marketer :

Comed Chemicals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Comtrix O 200 mg Tablet

Comtrix O 200 mg Tablet belongs to a class of medication called antibiotics used in the treatment of several bacterial infections of the urinary tract, ears, nose, throat, chest, lungs, etc. The bacterial infection is a condition in which harmful bacteria grows in the body and cause infection. It can infect any part of the body and multiple very quickly. Comtrix O 200 mg Tablet does not work against infections caused by the virus.

Comtrix O 200 mg Tablet is a combination of two drugs, namely: Cefixime (antibiotic) and Lactobacillus (probiotic). Cefixime belongs to the class of antibiotics that works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Thereby damages the bacterial cell wall and kills bacteria. Lactobacillus belongs to the class of probiotics (live micro-organisms that keeps the body healthy) that helps to restore good bacteria in the intestines. Thereby, it prevents diarrhoea and loss of beneficial bacteria due to the prolonged intake of Comtrix O 200 mg Tablet .

Take Comtrix O 200 mg Tablet as prescribed by your doctor. You are advised to take Comtrix O 200 mg Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience dizziness, nausea, vomiting, diarrhoea, stomach pain, indigestion, gas, bloating, headache or vaginal itching. Most of these side effects of Comtrix O 200 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Comtrix O 200 mg Tablet , penicillins, cephalosporin antibiotics or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, consult a doctor before taking Comtrix O 200 mg Tablet . Comtrix O 200 mg Tablet is not recommended for children below 10 years as the safety and effectiveness were not established. Drive only if you are alert as Comtrix O 200 mg Tablet may decrease alertness, cause confusion, unusual muscle movements or stiffness. You are recommended to complete the full course of Comtrix O 200 mg Tablet as prescribed by your doctor for effective results.

Uses of Comtrix O 200 mg Tablet

Bacterial infections

Directions for Use

Tablet: Swallow it as a whole with a glass of water. Do not crush, chew or break it. Syrup: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Medicinal Benefits

Comtrix O 200 mg Tablet is a combination of two drugs, namely: Cefixime and Lactobacillus used in the treatment of several bacterial infections. Cefixime is a broad-spectrum antibiotic that acts against both aerobic (grow in the presence of oxygen) and anaerobic (grow in the absence of oxygen) gram-negative and gram-positive bacteria. It interferes with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Thereby damages the bacterial cell wall and kills bacteria. Lactobacillus is a probiotic (live micro-organisms that keeps the body healthy) that helps to restore good bacteria in the intestines. Thereby, it prevents diarrhoea and loss of beneficial bacteria due to the prolonged intake of Comtrix O 200 mg Tablet .

Storage

Store in a cool and dry place away from sunlight
Side effects of Comtrix O 200 mg Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Avoid trigger foods that can cause allergic reactions, such as nuts, shellfish, or dairy products.
  • Keep a food diary to track potential food allergens.
  • Include omega-3 rich foods like salmon and walnuts to reduce inflammation.
  • Wear loose, comfortable clothing made from soft fabrics like cotton.
  • Apply cool compresses or take cool baths to reduce itching.
  • Use gentle soaps and avoid harsh skin products.
  • Reduce stress through relaxation techniques like meditation or deep breathing.
  • Notify your doctor about the fever caused by medication and follow their guidance to adjust or stop the medication.
  • Drink plenty of fluids, like water or electrolyte-rich beverages, and eat healthy food.
  • Get plenty of rest to help your body recover or adjust to the medication.
  • Track your temperature and report changes to your doctor.
  • Use fever-reducing medications like acetaminophen if recommended.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
Here are the steps to manage angioedema (Swelling Under The Skin) as a side effect of medication:
  • If you experience angioedema, inform your doctor immediately. Treatment can help keep the swelling under control.
  • Seek medical attention if symptoms are severe, such as difficulty breathing or swallowing.
  • Follow your doctor's instructions to manage symptoms, which may include stopping or adjusting the medication that triggered angioedema.
  • Your doctor may also recommend antihistamines, steroids, or other treatments to reduce swelling and inflammation.
  • Make dietary and lifestyle changes as recommended, such as avoiding trigger foods or reducing stress.
  • Monitor your condition closely and track your symptoms to report them to your doctor.
  • Consult your doctor again if symptoms worsen or do not improve or if you experience any new or concerning symptoms.
  • Let your doctor know if there are unsual symptoms after taking the medication, such as red patches on your skin.
  • Your doctor may change your medication, lower the dose, or stop the treatment to help manage the symptoms.
  • Avoid heavy physical activity and get plenty of rest to prevent further worsening of the symptoms.
  • Apply cold packs to the affected areas for relief.
  • Keep yourself hydrated or take supplements to get enough vitamins.
  • Over-the-counter pain relievers can help with discomfort.

Drug Warnings

If you are allergic to Comtrix O 200 mg Tablet , penicillins, cephalosporin antibiotics or any other medicines, please tell your doctor. If you have kidney or liver problems, weak immune system or inflammation of the large intestine, inform your doctor before taking Comtrix O 200 mg Tablet . If you are pregnant or breastfeeding, consult a doctor before taking Comtrix O 200 mg Tablet . Comtrix O 200 mg Tablet is not recommended for children below 10 years as the safety and effectiveness were not established. Drive only if you are alert as Comtrix O 200 mg Tablet may decrease alertness, cause confusion, unusual muscle movements or stiffness. You are recommended to complete the full course of Comtrix O 200 mg Tablet as prescribed by your doctor for effective results. Comtrix O 200 mg Tablet may interact with certain blood or urine tests giving false-positive results. Therefore, inform your doctor that you are taking Comtrix O 200 mg Tablet before undergoing any tests.

Drug-Drug Interactions

verifiedApollotooltip
CefiximeCholera, live attenuated
Severe

Drug-Drug Interactions

Login/Sign Up

CefiximeCholera, live attenuated
Severe
How does the drug interact with Comtrix O 200 mg Tablet:
Co-administration of Comtrix O 200 mg Tablet with Cholera vaccine may reduce the effectiveness of the vaccine.

How to manage the interaction:
Talk to your doctor before receiving the cholera vaccine if you are currently being treated with Comtrix O 200 mg Tablet or have been treated within the last 14 days. To ensure adequate vaccine response, you should not receive cholera vaccine until at least 14 days after you complete your antibiotic therapy. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Diet & Lifestyle Advise

  • Take probiotics after completing the full course of Comtrix O 200 mg Tablet to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhea.
  • Certain fermented foods like cheese, yogurt, kombucha, sauerkraut, and kimchi can help to restore the good bacteria of the intestine.
  • Include fiber-rich foods, as they can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fiber-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains such as brown rice and whole-grain bread should be included in your diet.
  • Make sure you drink plenty of water or other fluids every day while you are taking Comtrix O 200 mg Tablet .
  • Avoid alcohol consumption as it may increase adverse effects.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Comtrix O 200 mg Tablet Substitute

Substitutes safety advice

Product Substitutes

Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Sureshvarma D

Reviewed By

Sureshvarma D

MPharma

Last Updated

Jul 8, 2025 | 9:36 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
CEFIXIME-200MG+LACTOBACILLUS-60MILLIONS SPORESOther bacterial intestinal infections
Severe
CEFIXIME-200MG+LACTOBACILLUS-60MILLIONS SPORESDisorders resulting from impaired renal tubular function
Moderate

Drug-Diseases Interactions

Login/Sign Up

CEFIXIME-200MG+LACTOBACILLUS-60MILLIONS SPORESOther bacterial intestinal infections
Severe
How does the disease interact with Comtrix O 200 mg Tablet:
Almost all antibacterial medications have been associated to reports of Clostridioides difficile-associated diarrhoea (CDAD), formerly known as pseudomembranous colitis. It can vary from mild diarrhoea to deadly colitis. Clindamycin and lincomycin are two of the most frequent offenders.

How to manage the interaction:
Antibiotics may cause Clostridioides difficile-associated diarrhoea (CDAD), which may range from mild diarrhoea to fatal colitis. Appropriate fluid and electrolyte management, protein supplementation, antibacterial treatment of C difficile, and surgical evaluation is advised.
CEFIXIME-200MG+LACTOBACILLUS-60MILLIONS SPORESDisorders resulting from impaired renal tubular function
Moderate
How does the disease interact with Comtrix O 200 mg Tablet:
The kidneys remove the majority of beta-lactam antibiotics as unaltered drugs and, in certain situations, as metabolites as well. In individuals with poor renal function, the blood concentrations of beta-lactam antibiotics and their metabolites may rise and their half-lives may be prolonged. According to the particular product package labelling, dosage modifications may be required. These alterations should be based on the severity of the infection as well as the degree of renal impairment. Renal function tests should be carried out on a regular basis during extended and/or high-dose therapy since these medicines have occasionally been linked to nephrotoxicity and changes in renal function.

How to manage the interaction:
The serum concentration may be increased in patients with impaired kidney function as most beta-lactam antibiotics are eliminated by the kidney. Dose adjustment may be necessary for patients with kidney dysfunction. Regular renal function tests are advised.
CEFIXIME-200MG+LACTOBACILLUS-60MILLIONS SPORESAbnormal serum enzyme levels
Moderate
How does the disease interact with Comtrix O 200 mg Tablet:
Hepatitis cases have been associated to the usage of several cephalosporins. Alkaline phosphatase, AST, and ALT levels have all shown a brief spike. When these medications are provided to people with hepatic problems, caution and close observation are advised.

How to manage the interaction:
Caution and monitoring is recommended in patients with liver disorders.
CEFIXIME-200MG+LACTOBACILLUS-60MILLIONS SPORESEpilepsy
Moderate
How does the disease interact with Comtrix O 200 mg Tablet:
It has been suggested that cephalosporins can cause seizures. In particular in patients with a history of epilepsy and/or where prescribed doses of cephalosporins were exceeded because of renal impairment, cephalosporins have been associated with nonconvulsive status epilepticus (NCSE), encephalopathy, coma, asterixis, neuromuscular excitability, and myoclonia. Depending on the creatinine clearance, change the dosage. In individuals with known seizure disorders, anticonvulsant medication should be maintained. Patients should get a neurological exam to see if medication should be stopped if CNS side effects like seizures happen.

How to manage the interaction:
Cephalosporin antibiotics may trigger seizures. Dose adjustment may be needed.

FAQs

Drug-Drug Interactions Checker List

  • WARFARIN
  • FUROSEMIDE
  • DEXAMETHASONE
  • METHYLPREDNISOLONE
  • PREDNISONE
  • TACROLIMUS
  • CICLOSPORIN

Special Advise

If you are about to undergo any blood or urine tests, inform your doctor that you are taking Comtrix O 200 mg Tablet as it may interfere with these tests.

Disease/Condition Glossary

Bacterial infection: It is a condition in which harmful bacteria grows in the body and cause infection. It can target any part of the body and multiple very quickly. Bacteria come in three basic shapes, namely spherical, rod or spiral-shaped. Bacteria may be gram-positive (have thick cell wall) or gram-negative (do not have cell wall). Appropriate tests are done to identify bacterial strains and based on the results, proper medication is prescribed. Some common symptoms of bacterial infection include cough, fever and tiredness.

Have a query?

whatsapp Floating Button