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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
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Composition :

NICORANDIL-5MG

Manufacturer/Marketer :

Prevento Pharma

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Cordil-5 Tablet

Cordil-5 Tablet belongs to a class of medication called 'vasodilators' used to prevent or treat angina pectoris (heart-related chest pain) in adults who cannot take beta-blockers (blood pressure-lowering pills). Angina pectoris is a kind of chest pain due to decreased blood flow to the heart. It is a symptom of coronary artery disease.

Cordil-5 Tablet contains Nicorandil, a potassium-channel activator that opens potassium channels present on the muscle cells within the walls of blood vessels and relaxes these muscle cells and widens blood vessels. Thereby, Cordil-5 Tablet reduces the heart's workload by making it easier for the heart to pump blood around the body and does not require much oxygen. Also, Cordil-5 Tablet helps to prevent angina by increasing oxygen and blood supply to the heart muscle by widening coronary arteries within the heart.

Take Cordil-5 Tablet as prescribed by your doctor. You are advised to take Cordil-5 Tablet for as long as your doctor has prescribed it for you based on your medical condition. Some people may experience headache, nausea, vomiting, dizziness, weakness, flushing (reddening of the skin) or very fast, forceful or uneven heartbeat. Most of these side effects of Cordil-5 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are allergic to Cordil-5 Tablet or any other medicines, please tell your doctor. Do not take Cordil-5 Tablet if you are pregnant or breastfeeding and consult a doctor. Cordil-5 Tablet is not recommended for children as the safety and effectiveness were not established. Drive only if you are alert as Cordil-5 Tablet may cause dizziness or weakness. Avoid alcohol consumption with Cordil-5 Tablet as it may cause severely low blood pressure. Avoid taking vardenafil, sildenafil, tadalafil and riociguat with Cordil-5 Tablet as it may affect blood pressure.

Uses of Cordil-5 Tablet

Angina pectoris (heart related chest pain)

Directions for Use

Take Cordil-5 Tablet with or without food as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Cordil-5 Tablet contains Nicorandil, a potassium-channel activator used to prevent or treat angina pectoris (chest pain). Cordil-5 Tablet works by opening potassium channels present on the muscle cells within the blood vessels' walls and relaxes these muscle cells and widens blood vessels. Thereby, Cordil-5 Tablet reduces the heart's workload by making it easier for the heart to pump blood around the body and does not require much oxygen. Also, Cordil-5 Tablet helps to prevent angina by increasing oxygen and blood supply to the heart muscle by widening coronary arteries within the heart. Cordil-5 Tablet is given to adults who cannot tolerate other heart medicines such as calcium antagonists or beta-blockers. 

Storage

Store in a cool and dry place away from sunlight
Side effects of Cordil-5 Tablet
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
  • Always wear loose-fitting clothes which are suitable for your activity.
  • Include the diet containing fruits like watermelon, grapes, bananas and green leafy vegetables.
  • Drink plenty of water stay hydrated.
  • Avoid moving more and staying in hot sun.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Drug Warnings

If you are allergic to Cordil-5 Tablet or any other medicines, please tell your doctor. Avoid taking Cordil-5 Tablet if you have hypotension (severe low blood pressure), low blood volume, pulmonary oedema (accumulation of fluid in the lungs) or any heart problems. Do not take Cordil-5 Tablet if you are pregnant or breastfeeding and consult a doctor. Cordil-5 Tablet is not recommended for children as the safety and effectiveness were not established. Drive only if you are alert as Cordil-5 Tablet may cause dizziness or weakness. Avoid alcohol consumption with Cordil-5 Tablet as it may cause severely low blood pressure. Avoid taking vardenafil, sildenafil, tadalafil and riociguat with Cordil-5 Tablet as it may affect blood pressure. If you notice in blood in stools while taking Cordil-5 Tablet , inform your doctor immediately as it may be due to ulcers in the stomach, intestines or back passage.

Drug-Drug Interactions

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RamiprilAliskiren
Critical
RamiprilIrbesartan
Severe

Drug-Drug Interactions

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RamiprilAliskiren
Critical
How does the drug interact with Cordil-5 Tablet:
Taking aliskiren together with Cordil-5 Tablet may increase the risk of serious side effects such as kidney problems, low blood pressure, and high potassium levels in the blood. High levels of potassium can develop into a condition known as hyperkalemia, which in severe cases can lead to kidney problems, muscle paralysis and irregular heart rhythm.

How to manage the interaction:
Taking Cordil-5 Tablet with Aliskiren is not recommended, but can be taken if prescribed by a doctor. However, consult your doctor if you feel nausea, vomiting, weakness, confusion, tingling in the hands and feet, a sensation of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. You must drink enough fluids while taking these medications. It is advised to reduce the intake of foods high in potassium, including tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes. Do not discontinue any medications without a doctor's advice.
RamiprilIrbesartan
Severe
How does the drug interact with Cordil-5 Tablet:
Taking Cordil-5 Tablet together with Irbesartan may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Irbesartan with Cordil-5 Tablet together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
RamiprilPotassium acetate
Severe
How does the drug interact with Cordil-5 Tablet:
Taking Cordil-5 Tablet with potassium acetate may significantly increase potassium levels in the blood. High levels of potassium can develop into a condition known as hyperkalemia, which in severe cases can lead to kidney problems, muscle paralysis and irregular heart rhythm

How to manage the interaction:
Although there is a interaction between Cordil-5 Tablet and Potassium acetate, but it can be taken if prescribed by a doctor. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.
RamiprilAllopurinol
Severe
How does the drug interact with Cordil-5 Tablet:
Co-administration of Allopurinol with Cordil-5 Tablet may increase the risk of severe allergic reactions and infections.

How to manage the interaction:
Although there is a possible interaction between Allopurinol and Cordil-5 Tablet, you can take these medicines together if prescribed by your doctor. However, if you develop throat tightness, shortness of breath, itching, rash, swelling of the face, lips, or tongue, fever, and/or muscle pain or weakness, contact your doctor immediately. Also, let your doctor know if you notice signs of infection or experience chills, fever, sore throat, extreme tiredness, body pains, or other flu-like symptoms. Do not discontinue the medication without consulting a doctor.
RamiprilPotassium citrate
Severe
How does the drug interact with Cordil-5 Tablet:
Taking Potassium citrate with Cordil-5 Tablet may increase potassium levels in the blood. High potassium levels can lead to kidney problems, muscle paralysis, and abnormal heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Potassium citrate and Cordil-5 Tablet, you can take these medicines together if prescribed by your doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. It is advised to reduce the intake of potassium-rich foods. Do not discontinue any medications without a doctor's advice.
RamiprilLeflunomide
Severe
How does the drug interact with Cordil-5 Tablet:
Taking leflunomide with Cordil-5 Tablet can increase the risk of liver problems.

How to manage the interaction:
Although taking Cordil-5 Tablet with Leflunomide can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RamiprilTelmisartan
Severe
How does the drug interact with Cordil-5 Tablet:
Taking Cordil-5 Tablet with telmisartan may increase the risk of side effects such as low blood pressure, kidney function impairment, and high blood potassium.

How to manage the interaction:
Although there is a possible interaction, telmisartan can be taken with Cordil-5 Tablet if prescribed by the doctor. Consult the prescriber if you experience symptoms of high potassium such as nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Maintain adequate fluid intake during treatment with these medications. Do not discontinue the medications without consulting a doctor.
RamiprilKetoconazole
Severe
How does the drug interact with Cordil-5 Tablet:
Coadministration of Cordil-5 Tablet with ketoconazole may increase the blood level of Cordil-5 Tablet.

How to manage the interaction:
Although taking Cordil-5 Tablet with Ketoconazole can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, tiredness, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue using any medications without consulting a doctor.
RamiprilPotassium iodide
Severe
How does the drug interact with Cordil-5 Tablet:
Taking Potassium Iodide with Cordil-5 Tablet may significantly increase potassium levels in the blood. High levels of potassium can develop into a condition known as hyperkalemia, which in severe cases can lead to kidney problems, muscle paralysis and irregular heart rhythm.

How to manage the interaction:
Although there is a interaction between Potassium iodide and Cordil-5 Tablet, you can take these medicines together if prescribed by a doctor. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.
RamiprilSpironolactone
Severe
How does the drug interact with Cordil-5 Tablet:
Using Cordil-5 Tablet together with spironolactone may cause hyperkalemia (increase the levels of potassium in your blood).

How to manage the interaction:
Although taking spironolactone and captopril together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as weakness, confusion, numbness or tingling, and uneven heartbeat. Do not stop using any medications without consulting doctor.

Drug-Food Interactions

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NICORANDIL-5MGPotassium rich foods
Moderate

Drug-Food Interactions

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NICORANDIL-5MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Consuming potassium-rich foods while using Cordil-5 Tablet may increase the potassium levels in your blood. It is recommended to avoid potassium-rich foods while using Cordil-5 Tablet. If you experience a fast heartbeat, shortness of breath, chest pain, nausea, or vomiting, consult your doctor immediately.

Diet & Lifestyle Advise

  • Follow a cholesterol-lowering diet.
  • Consume low-salt and a low-fat diet.
  • Exercise regularly. It helps in maintaining proper weight and lowers cholesterol.
  • Limit salt and sugar intake.
  • Avoid smoking and alcohol consumption.
  • Choose healthy fats and cut down on trans-fat.
  • Include omega-3 fatty acids, fibre-rich food, fruits and vegetables.
  • Get active by doing any physical activity such as swimming, brisk walking or jogging. Take the stairs instead of elevators/lifts.

Habit Forming

No

Therapeutic Class

VASODILATORS

Cordil-5 Tablet Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Cordil-5 Tablet contains Nicorandil that works by relaxing and widening blood vessels. Thereby, Cordil-5 Tablet reduces the workload of the heart by making it easier for heart to pump blood around the body and does not require much oxygen. Also, Cordil-5 Tablet helps to prevent angina by increasing oxygen and blood supply to the heart muscle by widening coronary arteries within the heart.

Cordil-5 Tablet may cause headache as a common side effect especially in the first few days of treatment. However, if the condition persist or worsens, please consult a doctor so that the dose may be reduced initially.

Cordil-5 Tablet is not recommended for patients with severe hypotension (low blood pressure) as it may increase the risk of worsening the condition. Therefore, inform your doctor if you have low blood pressure before taking Cordil-5 Tablet .

You are not recommended to take aspirin (pain reliever) with Cordil-5 Tablet as co-administration of these two medicines may increase the risk of ulcers or other adverse effects. However, please consult a doctor before taking other medicines with Cordil-5 Tablet .

You are recommended to avoid taking Cordil-5 Tablet if you have hypotension (severe low blood pressure), low blood volume, pulmonary oedema (accumulation of fluid in the lungs) or any heart problems such as left ventricular failure with low filling pressure, cardiac decompensation or cardiogenic shock.

You are not recommended to take more than the prescribed dose of Cordil-5 Tablet as it may cause Cordil-5 Tablet overdose resulting in symptoms such as weakness, dizziness (signs of low blood pressure), fast or irregular heartbeat. However, if you experience any of these symptoms while taking Cordil-5 Tablet , please consult a doctor immediately.

Drug-Drug Interactions Checker List

  • VARDENAFIL
  • SILDENAFIL
  • TADALAFIL
  • RIOCIGAUT
  • DAPOXETINE
  • ASPIRIN
  • PREDNISOLONE
  • LISINOPRIL
  • RAMIPRIL
  • LOSARTAN
  • VALSARTAN
  • CANDESARTAN

Special Advise

  • Avoid consumption of alcohol with name as it may cause severe low blood pressure.
  • Regular exercise is recommended along with Cordil-5 Tablet for effective results.

Disease/Condition Glossary

Angina pectoris: It is a kind of chest pain caused due to decreased blood flow to the heart, which means insufficient oxygen supply to the heart muscle. The chest pain is often triggered by emotional stress or physical activity. Angina is a symptom of coronary artery disease. The symptoms of angina include dizziness, shortness of breath, nausea, tiredness, anxiety or excessive sweating. The risk factors for angina include smoking, diabetes, overweight, high blood pressure, high cholesterol, not exercising, or a history of heart disease. 

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