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About Coversyl Plus Tablet

Coversyl Plus Tablet belongs to a class of medication called 'anti-hypertensive agents' prescribed alone or with other drugs to lower the raised blood pressure. Hypertension (High blood pressure) is a condition in which the force exerted by the blood against the artery walls becomes so high that it causes health problems, such as heart disease.

Coversyl Plus Tablet contains two medicines: Perindopril (blood pressure-lowering agent) and Indapamide (diuretics or water pills). Perindopril is an angiotensin-converting enzyme or ACE inhibitor that lower increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). It allows these constricted blood vessels to relax and helps lower high blood pressure. On the other hand, Indapamide (diuretic) increases the amount of urine passed out from the kidneys. But unlike other water pills, it does not increase urine output. It effectively reduces excess fluid overload in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, both help lower high blood pressure, reducing heart attack or stroke chances.

Coversyl Plus Tablet is taken with or without food in a dose and duration as advised by the doctor. The doctor will adjust your dose according to your condition and response to the medicine. Sometimes, you may experience headaches, tiredness, slow heart rate, and nausea. Most of these side effects of Coversyl Plus Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Even if your blood pressure becomes normal, you should not stop using Coversyl Plus Tablet . Doing so may worsen your condition. Tell your doctor if you have had or currently have liver, kidney, or heart problems. In pregnancy and lactation, Coversyl Plus Tablet should only be taken after consulting your doctor. You should regularly monitor your blood pressure and heart rate. Please tell your doctor if you are taking any other medicines or are allergic to Coversyl Plus Tablet . Reducing the amount of table salt (sodium chloride) in your food often relieves the body's swelling.

Uses of Coversyl Plus Tablet

Hypertension (high blood pressure)

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Coversyl Plus Tablet is primarily used to treat hypertension (high blood pressure), reduce the heart's workload, and reduce the risk of any future heart attack or stroke. It contains two medicines: Perindopril (blood pressure-lowering agent) and Indapamide (diuretics or water pills). Perindopril lowers the increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). It allows these constricted blood vessels to relax and helps lower high blood pressure. On the other hand, Indapamide (diuretic) increases the amount of urine passed out from the kidneys. But unlike other water pills, it does not increase urine output too much. Thus, both help lower high blood pressure, reducing heart attack or stroke chances.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Coversyl Plus Tablet should not be given to people allergic to Coversyl Plus Tablet , have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease, liver disease, pregnant women or planning to get pregnant and breastfeeding women. Coversyl Plus Tablet is not recommended in neonates and children with worse kidney functioning (glomerular filtration rate <30 mL/min). The raised bilirubin level has been reported in some cases, so patients with liver diseases (like cirrhosis, jaundice, yellowing of skin/eye, etc.) should take the Coversyl Plus Tablet with caution. Coversyl Plus Tablet contains perindopril, which is a category D pregnancy drug, it can cause harm to the baby, so it is not recommended to be taken during pregnancy. Do not take Coversyl Plus Tablet with alcohol as it may cause low blood pressure (hypotension) with symptoms of dizziness, drowsiness, weariness, or sleepiness. Tell your doctor you are using Coversyl Plus Tablet before undergoing dental or other surgery. Your doctor might stop this medicine before the surgery. Coversyl Plus Tablet contains Indapamide, which positively reacts to drug tests, so if you are an athlete, be aware if you are taking Coversyl Plus Tablet and are undergoing a drug test.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Coversyl Plus Tablet:
Combining Aliskiren with Coversyl Plus Tablet can increase the risk of low blood pressure, high potassium levels, and kidney damage.

How to manage the interaction:
Taking Coversyl Plus Tablet with Aliskiren is not recommended, but can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Coversyl Plus Tablet:
Taking Coversyl Plus Tablet with Thioridazine can increase the risk of heart problems.

How to manage the interaction:
Taking Thioridazine with Coversyl Plus Tablet is not recommended, but can be taken if prescribed by the doctor.
IndapamideDroperidol
Critical
How does the drug interact with Coversyl Plus Tablet:
Taking Droperidol with Coversyl Plus Tablet can lead to severe heart problems.

How to manage the interaction:
Taking Droperidol with Coversyl Plus Tablet is not recommended, but can be taken if prescribed by the doctor.
IndapamideProtriptyline
Critical
How does the drug interact with Coversyl Plus Tablet:
Taking Protriptyline along with Coversyl Plus Tablet can lead to serious heart problems.

How to manage the interaction:
Taking Protriptyline with Coversyl Plus Tablet is not recommended, but can be taken if prescribed by the doctor.
How does the drug interact with Coversyl Plus Tablet:
Taking ketoconazole with Coversyl Plus Tablet can increase the risk of liver damage.

How to manage the interaction:
Although taking Ketoconazole and Coversyl Plus Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Coversyl Plus Tablet:
Co-administration of Allopurinol with Coversyl Plus Tablet may increase the risk of severe allergic reactions and infections.

How to manage the interaction:
Although there is a possible interaction between Allopurinol and Coversyl Plus Tablet, you can take these medicines together if prescribed by your doctor. However, if you develop throat tightness, shortness of breath, itching, rash, swelling of the face, lips, or tongue, fever, and/or muscle pain or weakness, signs of infection or experience chills, fever, sore throat, extreme tiredness, body pains, or other flu-like symptoms, contact your doctor immediately . Do not discontinue any medications without consulting a doctor.
How does the drug interact with Coversyl Plus Tablet:
Using Coversyl Plus Tablet together with piroxicam may reduce the effects of Coversyl Plus Tablet in lowering blood pressure, they may also increase the risk of kidney problems.

How to manage the interaction:
Co-administration of Piroxicam with Coversyl Plus Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, breathing difficulty, muscle pain, and irregular heart rhythm, contact a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Coversyl Plus Tablet:
Coversyl Plus Tablet when taken together with lithium may significantly increase the blood levels of lithium.

How to manage the interaction:
Although there is drug interaction between Coversyl Plus Tablet and lithium, but can be taken together if advised by a doctor. if experience dizziness, confusion, diarrhea, vomiting, muscle weakness, tremor (shaking of hand & legs) blurred vision, ringing in the ear, excessive thirst, and/or increased urination consult a doctor immediately. Do not discontinue medications without consulting a doctor.
PerindoprilPotassium hydrogencarbonate
Severe
How does the drug interact with Coversyl Plus Tablet:
Using Coversyl Plus Tablet together with potassium hydrogencarbonate may significantly increase potassium levels in the blood.

How to manage the interaction:
Co-administration of Coversyl Plus Tablet with Potassium hydrogencarbonate can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat contact your doctor immediately. Do not stop using any medications without a doctor's advice. Do not discontinue any medications without first consulting your doctor.
PerindoprilPotassium acetate
Severe
How does the drug interact with Coversyl Plus Tablet:
Taking potassium acetate with Coversyl Plus Tablet can increase the risk of kidney problems and abnormal heart rhythm.

How to manage the interaction:
Although taking Coversyl Plus Tablet and Potassium acetate together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat contact your doctor immediately. Do not stop using any medications without a doctor's advice. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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INDAPAMIDE-1.25MG+PERINDOPRIL-4MGPotassium rich foods
Moderate

Drug-Food Interactions

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INDAPAMIDE-1.25MG+PERINDOPRIL-4MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Tomatoes, Sweet Potatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Consuming Potassium containing food with Perindopril and Indapamide can increase the risk of high levels of potassium in your blood. Avoid consuming Potassium-containing food with Perindopril and Indapamide.

Diet & Lifestyle Advise

  • Create a well-balanced and healthy diet that includes vegetables, fruits, whole grains, legumes, omega-3-rich foods, and lean protein sources.
  • Keep your weight under control with a BMI of 19.5-24.9.
  • Avoid chronic stress, as it can raise your blood pressure.
  • Spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Be mindful of salt; consume no more than 2,300 mg each day.
  • Limit or avoid alcohol consumption.
  • Quitting smoking is the best strategy to lower the risk of heart disease.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Coversyl Plus Tablet Substitute

Substitutes safety advice
  • Perigard D Tablet 10's

    by Others

    10.72per tablet

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Coversyl Plus Tablet contains two medicines: Perindopril (blood pressure-lowering agent) and Indapamide (diuretics or water pills). Perindopril is an angiotensin-converting enzyme or ACE inhibitor that lower increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). Indapamide (diuretic) increases the amount of urine passed out from the kidneys. Thus, both help lower high blood pressure, reducing heart attack or stroke chances.

It is advised to continue your medicine even after your blood pressure is under control or becomes normal, as blood pressure can shoot up at any time. If you have any discomfort, please consult your doctor immediately.

Usually, Coversyl Plus Tablet is prescribed for a long-term treatment ranging from months to years for treating heart-related conditions and disorders. However, taking it on your own for years without a doctor's consent can be fatal. Hence, only take it as long as your doctor prescribes it.

Before surgery, you should inform your doctor that you are taking Coversyl Plus Tablet to reduce your blood pressure when used along with anaesthesia, which is given before a major operation.

Coversyl Plus Tablet contains Indapamide, which gives a positive reaction to drug tests. If you are an athlete, be aware if you are taking Coversyl Plus Tablet and are undergoing a drug test.

Drug-Drug Interactions Checker List

  • NITROGLYCERIN
  • ALISKIREN
  • LOSARTAN
  • VALSARTAN
  • OLMESARTAN
  • CANDESARTAN
  • CAPTOPRIL
  • ENALAPRIL
  • IBUPROFEN
  • NAPROXEN
  • LITHIUM
  • ESTRAMUSTINE
  • AMILORIDE
  • TRIAMTERENE

Special Advise

  • Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.

Disease/Condition Glossary

Hypertension: The blood exerts increased pressure on the walls of blood vessels leading to hypertension. High blood pressure is expressed as systolic/diastolic pressure. Systolic pressure is the pressure in the arteries when the heart beats or pumps out blood. Diastolic pressure is the pressure in the arteries between the heartbeats. Blood pressure is measured in millimetres of mercury (mmHg) by a blood pressure monitor called a sphygmomanometer. Some of the symptoms are headache, dizziness, nosebleeds, altered vision, chest pain, weakness, and shortness of breath. However, most of the time, the signs and symptoms of hypertension are none.

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