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Written By ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
COD available

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Composition :

CYCLOSERINE-250MG

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Coxerin Capsule

Coxerin Capsule belongs to the group of medicines called antibiotic drugs primarily used to treat tuberculosis. It is also used to treat kidney infections. Tuberculosis is an infectious disease that mainly affects the lungs. Coxerin Capsule should not be used alone and must be given in combination with other tuberculosis medications. Coxerin Capsule does not work against infections caused by the virus, including cold and flu.

Coxerin Capsule consists of a medicine called 'Cycloserine' that works by inhibiting bacteria's cell-wall biosynthesis in susceptible strains of bacteria that causes tuberculosis (Mycobacterium tuberculosis).

Coxerin Capsule should be taken as prescribed by the doctor. The dose and duration of Coxerin Capsule can vary depending on your condition and the severity of the infection. Sometimes, you may experience certain common side effects, such as dizziness, drowsiness, mood changes, headache, numbness, and tingling. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not stop taking Coxerin Capsule despite symptomatic relief. Treat your condition effectually, and continue taking Coxerin Capsule for as long as it has been prescribed. Do not take Coxerin Capsule if you have a seizure disorder, severe kidney disease, depression, anxiety or mental illness. Also, do not take Coxerin Capsule if you are an alcoholic. Consult your doctor before taking Coxerin Capsule if you are pregnant. Avoid breastfeeding while taking Coxerin Capsule as it passes into breast milk. Coxerin Capsule may cause dizziness and mood changes, so drive with caution if you experience these signs. Avoid consuming alcohol with Coxerin Capsule as it might increase your risk of seizures. Inform your doctor immediately if you experience/notice confusion, seizure, or trouble speaking after taking Coxerin Capsule .

Uses of Coxerin Capsule

Tuberculosis (TB)

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Coxerin Capsule contains 'Cycloserine' that works by inhibiting bacteria's cell-wall biosynthesis in susceptible strains of bacteria that causes tuberculosis (Mycobacterium tuberculosis).

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Before starting Coxerin Capsule , please inform your doctor if you have a history of seizure disorder and kidney problems. Consult your doctor before taking Coxerin Capsule if you are pregnant. Avoid breastfeeding while taking Coxerin Capsule as it passes into breast milk. Coxerin Capsule may cause dizziness, drowsiness or mood changes, so drive cautiously. Avoid consuming alcohol with Coxerin Capsule as it might increase the risk of seizures. Before taking Coxerin Capsule , inform your doctor if you are already taking medicines like ethionamide or isoniazid. Seek medical help immediately if you notice overactive reflexes, tremors or shaking, rapid weight gain, severe drowsiness, dizziness or spinning sensation while on this medication.

Drug-Drug Interactions

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Severe

Drug-Drug Interactions

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How does the drug interact with Coxerin Capsule:
Bupropion can cause seizures (fits) in rare cases but combining Bupropion with Coxerin Capsule may enhance that risk.

How to manage the interaction:
Co-administration of bupropion along with Coxerin Capsule can lead to an interaction, but it can be taken if recommended by a doctor. However, if you experience Memory loss, Confusion, Insomnia (difficulty in sleeping), Retching, Difficulty, speaking, Dizziness, Headache, or Convulsion consult a doctor. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Coxerin Capsule:
Using Coxerin Capsule together with alcohol may increase the risk or severity of central nervous system side effects.

How to manage the interaction:
There may be a possibility of interaction between Coxerin Capsule and Ethanol, but it can be taken if prescribed by a doctor. However, if you experience feeling dizzy or sleepy, depressed, having trouble remembering things, feeling confused, or having convulsions, contact a doctor right away. Do not stop using any medications without talking to a doctor.
CycloserineCholera, live attenuated
Severe
How does the drug interact with Coxerin Capsule:
The effects of Cholera, live attenuated can be decreased when used in combination with Coxerin Capsule.

How to manage the interaction:
Co-administration of Cholera, live attenuated along with Coxerin Capsule can lead to an interaction, but it can be taken if recommended by a doctor. However, if you experience any unusual side effects, consult a doctor. Do not discontinue any medications without first consulting your doctor.
CycloserineIopamidol
Severe
How does the drug interact with Coxerin Capsule:
Combining Coxerin Capsule with Iopamidol can increase the risk of seizures (fits).

How to manage the interaction:
There may be a possibility of interaction between Coxerin Capsule and Iopamidol, but it can be taken if prescribed by a doctor. If you are elderly, going through alcohol or drug withdrawal, have a history of seizures (fits), or have a brain related condition, you may be more vulnerable. If you experience symptoms like confusion, a gazing spell, or Uncontrollable twitching movements of the arms and legs, loss of awareness or consciousness, alterations in emotions, consult a doctor. They will be able to help you and provide the necessary care. Do not discontinue any medications without first consulting your doctor.
Severe
How does the drug interact with Coxerin Capsule:
Combining Coxerin Capsule with Iohexol can increase the risk of seizures (fits).

How to manage the interaction:
There may be a possibility of interaction between Coxerin Capsule and Iohexol, but it can be taken if prescribed by a doctor. If you experience symptoms like confusion, a gazing spell, or Uncontrollable twitching movements of the arms and legs, loss of awareness or consciousness, alterations in emotions, consult a doctor. They will be able to help you and provide the necessary care. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Coxerin Capsule:
Combining Coxerin Capsule with Tramadol can increase the risk of seizures (fits).

How to manage the interaction:
There may be a possibility of interaction between Coxerin Capsule and Tramadol, but it can be taken if prescribed by a doctor. If you are elderly, going through alcohol or drug withdrawal, have a history of seizures (fits), or have a brain related condition, you may be more vulnerable. If you experience symptoms like confusion, a gazing spell, or Uncontrollable twitching movements of the arms and legs, loss of awareness or consciousness, alterations in emotions, consult a doctor. They will be able to help you and provide the necessary care. Do not discontinue any medications without first consulting your doctor.
CycloserineIomeprol
Severe
How does the drug interact with Coxerin Capsule:
Combining Coxerin Capsule with Iomeprol can increase the risk of seizures (fits).

How to manage the interaction:
There may be a possibility of interaction between Coxerin Capsule and Iomeprol, but it can be taken if prescribed by a doctor. If you are elderly, going through alcohol or drug withdrawal, have a history of seizures (fits), or have a brain related condition, you may be more vulnerable. If you experience symptoms like confusion, a gazing spell, or Uncontrollable twitching movements of the arms and legs, loss of awareness or consciousness, alterations in emotions, consult a doctor. They will be able to help you and provide the necessary care. Do not discontinue any medications without first consulting your doctor.
CycloserineMetrizamide
Severe
How does the drug interact with Coxerin Capsule:
Combining Coxerin Capsule with Metrizamide can increase the risk of seizures (fits).

How to manage the interaction:
There may be a possibility of interaction between Coxerin Capsule and Metrizamide, but it can be taken if prescribed by a doctor. If you are elderly, going through alcohol or drug withdrawal, have a history of seizures (fits), or have a brain related condition, you may be more vulnerable. If you experience symptoms like confusion, a gazing spell, or Uncontrollable twitching movements of the arms and legs, loss of awareness or consciousness, alterations in emotions, consult a doctor. They will be able to help you and provide the necessary care. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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CYCLOSERINE-250MGCaffeine containing foods/drinks
Severe

Drug-Food Interactions

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CYCLOSERINE-250MGCaffeine containing foods/drinks
Severe
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Co-administration of Cyclosporine and caffeine containing products can lead to increased risk of negative effects. Avoid consumption of caffeine containing products while on Cyclosporine. If you experience symptoms like sleeplessness, irritability, shaking, anxiety, psychoses, and seizures(fits), consult a doctor. Do no stop taking the medication without consulting a doctor.

Diet & Lifestyle Advise

  • Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.
  • Foods rich in vitamin C, such as kiwi, broccoli and bell pepper, help improve the immune system.
  • Avoid processed and fried foods.
  • Warm ginger tea or warm soup can help relieve a cough.
  • Avoid foods and drinks containing histamine or tyramine, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine and beer.
  • To help prevent certain side effects (such as nerve problems) from this medication, your doctor may advise you to take vitamin B6 (pyridoxine).
  • Quit smoking and avoid alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTI- TUBERCULOSIS

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Cycloserine is a broad-spectrum antibiotic, which may be bacteriostatic or bactericidal. It works by blocking peptidoglycan's formation (a substance important for forming the cell walls of bacteria). Eventually, the walls of the bacteria become weak and lead to the death of the bacteria.

Do not stop taking Coxerin Capsule despite symptomatic relief. Treat your condition effectually, continue taking Coxerin Capsule for as long as it has been prescribed for you.

Coxerin Capsule might decrease the effectiveness of oral contraceptives (birth control pills). This could lead to an unplanned pregnancy. Instead, use a reliable barrier method of contraception such as condoms or the coil while taking Coxerin Capsule . Consult your doctor if you have any concerns regarding this, your doctor may suggest an alternate contraception method.

After taking Coxerin Capsule , one may rarely experience mood changes like confusion, depressed mood, unusual thoughts or behaviour. Inform your doctor right away if you notice/experience any of these symptoms.

Cycloserine might interfere with live bacterial vaccines and cause them not to work as well. Do not have any immunizations /vaccinations while on this medication unless you say to.

Coxerin Capsule has been associated in a few instances with vitamin B12 and/or folic acid deficiency, megaloblastic anaemia and sideroblastic anaemia. Consult your doctor for further advice.

Drug-Drug Interactions Checker List

  • CETIRIZINE
  • DIPHENHYDRAMINE
  • ALPRAZOLAM
  • ZOLPIDEM
  • CODEINE
  • ETHIONAMIDE
  • ISONIAZID

Special Advise

  • You may need frequent blood tests to check your kidney and liver function.
  • Coxerin Capsule may cause live bacterial vaccines (such as typhoid) not to work. Do not have any immunization/vaccinations while using this medication unless your doctor tells you to.

Disease/Condition Glossary

Tuberculosis (TB): Tuberculosis is an infectious disease that affects the lungs, but it can also spread to other body parts such as kidneys, brain, spine and bone marrow. Tuberculosis is caused by a bacteria named Mycobacterium tuberculosis. It is a contagious disease that can spread to others through small droplets released into the air by a person suffering from tuberculosis. Symptoms include a cough that lasts for a few weeks, pain while coughing or normal breathing, unexplained fatigue, fever, night sweats, and loss of appetite and weight. People who smoke or consume alcohol, people diagnosed with HIV, and immune system problems are more likely at risk of developing active TB.

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