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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
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Consume Type :

ORAL

Return Policy :

Not Returnable

About Coxigo-P 60mg/500mg Tablet

Coxigo-P 60mg/500mg Tablet belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) used to relieve pain and inflammation in the conditions such as osteoarthritis, rheumatoid arthritis, gouty arthritis, ankylosing spondylitis, tooth pain, headache, nerve pain, muscular pain, back pain, fever, cold, and flu. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body.

Coxigo-P 60mg/500mg Tablet is a combination of two drugs, namely: Etoricoxib and Paracetamol. Coxigo-P 60mg/500mg Tablet works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes another chemical prostaglandin which causes pain and inflammation. By blocking the effect of COX enzymes, lesser prostaglandins are produced. This helps in reducing mild to moderate pain and inflammation at the injured or damaged site.

You are advised to take Coxigo-P 60mg/500mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as flatulence, constipation, nausea, diarrhoea, and swelling of hands and feet. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. Coxigo-P 60mg/500mg Tablet may cause sleepiness and dizziness, so drive with caution. Coxigo-P 60mg/500mg Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol as it could lead to increased dizziness; it might also increase stomach bleeding risk. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Coxigo-P 60mg/500mg Tablet

Pain relief, Osteoarthritis, Rheumatoid arthritis, Gouty arthritis, Ankylosing spondylitis

Directions for Use

Take Coxigo-P 60mg/500mg Tablet with or after food. Swallow Coxigo-P 60mg/500mg Tablet as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Coxigo-P 60mg/500mg Tablet is a combination of two Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), namely: Etoricoxib and Paracetamol. Coxigo-P 60mg/500mg Tablet is used to relieve pain in osteoarthritis, rheumatoid arthritis, gouty arthritis and ankylosing spondylitis, tooth pain, headache, nerve pain, muscular pain, back pain, fever, cold, and flu. Coxigo-P 60mg/500mg Tablet works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes another chemical prostaglandin. These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser prostaglandins are produced. This helps in reducing mild to moderate pain and inflammation at the injured or damaged site.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Coxigo-P 60mg/500mg Tablet if you are allergic to Coxigo-P 60mg/500mg Tablet or other NSAIDs. Inform your doctor if you have stomach ulcers, or have suffered bleeding problems, clotting problems, inflammatory bowel disease, heart failure, high blood pressure, diabetes, high cholesterol, severe heart, liver or kidney problems. If you have had any recent heart surgery, do not take Coxigo-P 60mg/500mg Tablet unless prescribed by the doctor, as Coxigo-P 60mg/500mg Tablet may increase the risk of heart attack or stroke. Consult your doctor if you are pregnant or breastfeeding. Coxigo-P 60mg/500mg Tablet may cause sleepiness and dizziness, so drive only if you are alert. Coxigo-P 60mg/500mg Tablet should not be given to children as safety has not been established. Avoid consuming alcohol along with Coxigo-P 60mg/500mg Tablet as it could lead to increased drowsiness and can increase the risk of stomach bleeding. Stop taking Coxigo-P 60mg/500mg Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take any other NSAIDs for pain relief along with Coxigo-P 60mg/500mg Tablet unless prescribed. 

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Coxigo-P 60mg/500mg Tablet:
Co-administration of Coxigo-P 60mg/500mg Tablet and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Coxigo-P 60mg/500mg Tablet and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Coxigo-P 60mg/500mg Tablet:
Co-administration of Coxigo-P 60mg/500mg Tablet may decrease the excretion rate of Oxazepam which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Oxazepam and Coxigo-P 60mg/500mg Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolLomitapide
Severe
How does the drug interact with Coxigo-P 60mg/500mg Tablet:
Co-administration of Lomitapide and Coxigo-P 60mg/500mg Tablet may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Coxigo-P 60mg/500mg Tablet and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Coxigo-P 60mg/500mg Tablet:
Co-administration of Teriflunomide with Coxigo-P 60mg/500mg Tablet may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Coxigo-P 60mg/500mg Tablet with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Coxigo-P 60mg/500mg Tablet:
Co-administration of Coxigo-P 60mg/500mg Tablet and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Coxigo-P 60mg/500mg Tablet and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ParacetamolMipomersen
Severe
How does the drug interact with Coxigo-P 60mg/500mg Tablet:
Co-administration of Mipomersen with Coxigo-P 60mg/500mg Tablet may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Coxigo-P 60mg/500mg Tablet and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ParacetamolValdecoxib
Severe
How does the drug interact with Coxigo-P 60mg/500mg Tablet:
Co-administration of Coxigo-P 60mg/500mg Tablet and Valdecoxib may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Coxigo-P 60mg/500mg Tablet and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.
How does the drug interact with Coxigo-P 60mg/500mg Tablet:
Co-administration of ketamine and Coxigo-P 60mg/500mg Tablet may decrease the effectiveness of Ketamine which could result in a higher blood level.

How to manage the interaction:
Although taking Ketamine and Coxigo-P 60mg/500mg Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy; apply a cold or hot compress on the joints for 15-20minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTI- INFLAMMATORY AGENTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Coxigo-P 60mg/500mg Tablet works by blocking the effect of chemical messengers that cause pain and inflammation.

Coxigo-P 60mg/500mg Tablet is used to reduce and relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, gouty arthritis and ankylosing spondylitis. Arthritis is the tenderness and swelling of the joints.

Avoid taking Coxigo-P 60mg/500mg Tablet if you have stomach ulcers, bleeding problems, or heart problems. Talk to your doctor regarding your concerns; he/she may prescribe alternate medicine.

Diarrhoea might be a side-effect of Coxigo-P 60mg/500mg Tablet. Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Coxigo-P 60mg/500mg Tablet might cause swelling of feet and hands due to fluid retention (oedema). While lying down, raise your legs above by putting a pillow below them. Follow a low-salt diet as it might help in reducing fluid build-up.

Coxigo-P 60mg/500mg Tablet along with birth control pills might increase the risk of side effects. Please consult your doctor, he/she may suggest an alternate method of contraception.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • WARFARIN
  • SALBUTAMOL
  • LITHIUM
  • ENALAPRIL
  • RAMIPRIL
  • LOSARTAN
  • VALSARTAN
  • MINOXIDIL
  • DIGOXIN
  • RIFAMPICIN
  • RANITIDINE
  • CYCLOSPORINE
  • TACROLIMUS
  • METOCLOPRAMIDE
  • DOMPERIDONE
  • CHOLESTYRAMINE

Special Advise

  • Coxigo-P 60mg/500mg Tablet might cause changes in blood tests. Inform the person doing the tests that you are taking Coxigo-P 60mg/500mg Tablet.

Disease/Condition Glossary

Pain: Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp; it might be constant or may come and go. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific area of the body). The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures, and arthritis.

Osteoarthritis: It is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering of cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms of osteoarthritis include pain, stiffness, inflammation and tenderness.

Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities and loss of joint function. 

Gouty arthritis: It is caused due to deposits of excess uric acid crystals in the joints, which leads to pain and inflammation in the joints. Symptoms include pain, swelling, and redness in the joints, mostly the big toe.

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