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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
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Composition :

PANCREATIN-300MG

Manufacturer/Marketer :

Adlib Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Creact 25000 Capsule

Creact 25000 Capsule is a pancreatic enzyme supplement indicated for the treatment of exocrine pancreatic insufficiency (pancreatin enzyme deficiency) due to cystic fibrosis (an inherited disorder that damages the lungs and digestive system), chronic pancreatitis (inflammation of the pancreas), or other conditions. Exocrine pancreatic insufficiency occurs in people whose bodies do not make enough of their own enzymes.

Creact 25000 Capsule contains Pancreatin, which is a combination of digestive enzymes such as porcine-derived lipases, proteases, and amylases. These enzymes help in the digestion of food. Creact 25000 Capsule mixes thoroughly with the food and helps in digestion as it passes through the gut.

You are advised to take Creact 25000 Capsule for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, Creact 25000 Capsule may cause certain common side-effects such as nausea, mild stomach pain, diarrhoea, and mild skin rash. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Inform your doctor before taking Creact 25000 Capsule if you have gout, asthma, or any disease condition. Consult your doctor before taking Creact 25000 Capsule if you are pregnant or breastfeeding. Creact 25000 Capsule may cause dizziness, so drive with caution. It is unknown whether alcohol interacts with Creact 25000 Capsule ; please consult your doctor if you have any concerns regarding this. Creact 25000 Capsule can be given to children if prescribed by the doctor; the dose depends upon the child’s age and body weight.

Uses of Creact 25000 Capsule

Pancreatic insufficiency (pancreatin enzyme deficiency)

Directions for Use

Capsule/Minimicrospheres: Swallow it as a whole with a glass of water; do not chew or crush the capsule/minimicrospheres.Granules: Mix the granules in apple/pineapple/orange juice or yoghurt; swallow the mixture directly without chewing. Do not mix pancreatin with very hot food/liquids.

Medicinal Benefits

Creact 25000 Capsule is a pancreatic enzyme supplement indicated for the treatment of exocrine pancreatic insufficiency (pancreatin enzyme deficiency) due to cystic fibrosis (an inherited disorder that damages the lungs and digestive system), chronic pancreatitis (inflammation of the pancreas), or other conditions. Pancreatin is a combination of digestive enzymes such as porcine-derived lipases, proteases, and amylases. These enzymes help in the digestion of food. Creact 25000 Capsule mixes thoroughly with the food and helps in digestion as it passes through the gut. Creact 25000 Capsule may also be used to treat steatorrhea (oily, smelly stools due to lack of fat absorption). 

Storage

Store in a cool and dry place away from sunlight
Side effects of Creact 25000 Capsule
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Drug Warnings

Do not take Creact 25000 Capsule if you are allergic to pork (pig), cow or buffalo products. Consult your doctor if you experience stomach pain, swelling, constipation, and vomiting as patients taking Creact 25000 Capsule with cystic fibrosis may develop a rare bowel condition called fibrosing colonopathy. Inform your doctor before taking Creact 25000 Capsule if you have gout, asthma, or any disease condition. Consult your doctor before taking Creact 25000 Capsule if you are pregnant or breastfeeding. Creact 25000 Capsule may cause dizziness, so drive with caution. It is unknown whether alcohol interacts with Creact 25000 Capsule ; please consult your doctor if you have any concerns regarding this. Creact 25000 Capsule can be given to children if prescribed by the doctor; the dose depends upon the child’s age and body weight.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

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Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat small portions of meals 3-5 times a day as larger meals make the digestive system work overtime.
  • Include diet rich in fruits and vegetables.
  • Avoid processed, deep-fried foods as they are hard to digest.
  • Maintain a balanced diet which includes proteins, carbohydrates, and fats. 
  • Stay hydrated by drinking enough water as it helps the digestive system to function smoothly.
  • Avoid highly processed foods which contain trans-fat, hydrogenated fats, and saturated fats. Instead of include foods containing monounsaturated, polyunsaturated and omega-3 fatty acids. Include olive oil, peanut oil, seeds, nuts, salmon, and tuna fish as they contain healthy fats
  • Avoid foods rich in fibre such as brown rice, barley, lentils, and peas as they might interfere with the enzyme activity.
  • Avoid or limit alcohol consumption as it can cause increased damage to the pancreas.

Habit Forming

No

Therapeutic Class

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Author Details

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Drug-Diseases Interactions

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FAQs

Creact 25000 Capsule contains ‘pancreatin enzymes’ breakdown food and converts it into energy. Creact 25000 Capsule is a combination of amylase (to digest starch), protease (to digest protein) and lipase (to digest fat). Thus, together it fulfils the digestive enzymes requirements in the pancreatitis conditions (inflammation of the pancreas), pancreatic cancer, post-surgery of the pancreas, and steatorrhea (loose fatty stool due to poor fat absorption).  

Creact 25000 Capsule is a pancreatic enzyme derived from the pancreatic organs of pigs used for food. Consult your doctor before taking Creact 25000 Capsule if you are allergic to the pig (pork), cow products or buffalo products.

Creact 25000 Capsule might interfere with the absorption and reduce the effectiveness of folic acid and iron. To prevent this, maintain a minimum gap between both.

Diarrhoea might be a side-effect of Creact 25000 Capsule . Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience watery diarrhoea or if you find blood in stools. Do not take anti-diarrhoeal medicine on your own.

Mixing Creact 25000 Capsule with non-acidic food or liquids, chewing or crushing may cause irritation in the mouth. It might also change the way Creact 25000 Capsule works in the body. Do not hold Creact 25000 Capsule or its contents in your mouth.

To treat your condition effectually continue taking Creact 25000 Capsule for as long as your doctor has prescribed it. Many patients will need to take Creact 25000 Capsule for the rest of their lives. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Creact 25000 Capsule .

Drug-Drug Interactions Checker List

  • CALCIUM
  • CALCITRIOL
  • FERROUS SULPHATE
  • IRON

Special Advise

  • Try to avoid taking an antacid within 1 hour before or after you take Creact 25000 Capsule . Simultaneous use of antacids containing calcium carbonate and/or magnesium hydroxide may lead to pancreatin deficiency. 

Disease/Condition Glossary

Exocrine pancreatic insufficiency: Pancreas play an important role in the digestion of food. It produces enzymes which help in the breakdown of food and absorption of nutrients. Exocrine pancreatic insufficiency occurs in people whose bodies do not make enough of their own enzymes. This leads to the inability of proper food digestion due to the pancreas' lack of a digestive enzyme. Exocrine pancreatic insufficiency could occur due to various conditions such as cystic fibrosis (an inherited disorder that damages the lungs and digestive system), pancreatitis (inflammation of the pancreas), diabetes, celiac disease (inability to digest gluten), pancreatic cancer, inflammatory bowel disease, Zollinger-Ellison disease, pancreatic or stomach surgery. Exocrine pancreatic insufficiency symptoms include abdominal pain, bloating, diarrhoea, flatulence, weight loss, and steatorrhea (loose, fatty, smelly stools). 

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