apollo
logo
0Login
Introducing Our Latest Arrival!
CRIZALK 250MG CAPSULE

CRIZALK 250MG CAPSULE

Consult Doctor
Prescription drug
 Trailing icon

Composition

CRIZOTINIB-250MG

Manufacturer/Marketer

Pfizer Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Aug-2024

for this medicine

About CRIZALK CAPSULE

CRIZALK CAPSULE belongs to the group of medicines called anti-cancer medicines. It is used to treat lung cancer called non-small cell lung cancer (NSCLC) in adults. Non-small cell lung cancer is a condition in which malignant (cancer) cells develop in the lung tissues. Non-small cell lung cancer is classified into numerous categories. The most important risk factor for non-small cell lung cancer is smoking.

CRIZALK CAPSULE contains the active substance Crizotinib, a medicine used to treat adults with lung cancer called non-small cell lung cancer (NSCLC). It works by inhibiting a type of enzyme called tyrosine kinase and slowing down or stopping cancer cell growth. CRIZALK CAPSULE is only given to patients whose disease is due to an alteration in the gene for ALK tyrosine kinase.

Always use this medicine exactly as your doctor has told you. You must keep to your doctor's instructions to get the maximum benefit. Sometimes, you may experience specific common side effects, such as visual disturbances or stomach upset, including vomiting, diarrhoea, nausea, tiredness, and dizziness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not take CRIZALK CAPSULE if you are allergic to CRIZALK CAPSULE or any of its ingredients. CRIZALK CAPSULE may cause tiredness and dizziness, so drive with caution. Avoid consuming alcohol with CRIZALK CAPSULE as it could lead to increased dizziness. CRIZALK CAPSULE is not recommended for children as safety and effectiveness have not been established. Inform your healthcare professional if you are a pregnant or breastfeeding woman so that your doctor decides whether CRIZALK CAPSULE can be taken or not. Keep your doctor informed about your health condition and medicines to rule out any side effects. While on CRIZALK CAPSULE treatment, you should avoid eating grapefruit or consuming grapefruit juice since they may alter the amount of CRIZALK CAPSULE in your body.

Uses of CRIZALK CAPSULE

Non-small cell lung cancer (NSCLC)

Medicinal Benefits

CRIZALK CAPSULE contains the active substance Crizotinib, a medicine used to treat adults with non-small cell lung cancer (NSCLC). CRIZALK CAPSULE is only given to patients whose disease is due to an alteration in the gene for ALK tyrosine kinase. It works by inhibiting a type of enzyme called tyrosine kinase and slowing down or stopping cancer cell growth.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of CRIZALK CAPSULE

  • Visual disturbance
  • Stomach upset
  • Vomiting
  • Diarrhoea
  • Nausea
  • Constipation
  • Decreased appetite
  • Tiredness
  • Dizziness
  • Metallic taste
  • Abdomen pain

Drug Warnings

Do not take CRIZALK CAPSULE if you are allergic to CRIZALK CAPSULE or any of its ingredients. CRIZALK CAPSULE may cause tiredness and dizziness, so drive with caution. Avoid consuming alcohol along with CRIZALK CAPSULE as it could lead to increased dizziness. CRIZALK CAPSULE is not recommended for children as safety and effectiveness have not been established. Consult your doctor if you are a pregnant or breastfeeding woman; your doctor will decide whether the CRIZALK CAPSULE can be taken or not. Keep your doctor informed about your health condition and medicines to rule out any side effects. It is essential to take CRIZALK CAPSULE every day, as long as your doctor prescribes it. Contact your doctor immediately if you cannot take medicine as your doctor prescribed or feel you do not need it anymore. Do not stop taking this medicine on your own. People with liver, kidney or heart disorders, lung inflammation, stomach or intestine problems, and vision disorders should consult the doctor before taking the CRIZALK CAPSULE.

Drug Interactions

Drug-Drug Interactions: CRIZALK CAPSULE may interact with various medications, including medicines used to treat fungal infections (e.g. ketoconazole, itraconazole, posaconazole, and voriconazole), medicines used to treat bacterial infections (e.g. clarithromycin, telithromycin, and erythromycin), medicines used to treat AIDS/HIV (e.g. atazanavir, ritonavir, and cobicistat), medicines used to treat seizures or fits (e.g. phenytoin, carbamazepine or phenobarbital), medications used to treat tuberculosis (e.g. rifabutin, rifampicin), and a herbal product used to treat depression (e.g. St. John's wort).

Drug-Food Interactions: You must not drink alcohol or grapefruit juice or eat grapefruit while on treatment.

Drug-Disease Interactions: CRIZALK CAPSULE should be used with caution in patients with liver, kidney or heart disorders, lung inflammation, stomach or intestine problems, and vision disorders.

Drug-Drug Interactions Checker List

  • KETOCONAZOLE
  • ITRACONAZOLE
  • POSACONAZOLE
  • VORICONAZOLE
  • CLARITHROMYCIN
  • TELITHROMYCIN
  • ERYTHROMYCIN
  • ATAZANAVIR
  • RITONAVIR
  • COBICISTAT
  • CARBAMAZEPINE
  • PHENOBARBITAL
  • RIFABUTIN
  • RIFAMPICIN
  • ST JOHN'S WORT

Habit Forming

No

Diet & Lifestyle Advise

  • Watch out for triggers that worsen the cough, such as smoke, foods, air-conditioning, high altitude, etc.
  • Exercise moderately. Eat healthily.
  • Follow a pulmonary rehabilitation program. It includes exercise, disease education, and group therapy.
  • Quit smoking and alcohol.
  • Get ample rest.
  • Include green leafy vegetables, sweet potatoes, broccoli, tomatoes, carrots, mangoes, citrus fruits, berries, and cocoa.
  • Lean proteins such as fish, meat, and poultry are the best.
  • Hydration is important. Drink plenty of water, herbal tea, and vegetable and fruit juices.
  • Avoid processed and refined foods.

Special Advise

  • If you have a fever or an infection, call your doctor. Your doctor may perform blood tests, and if the findings are abnormal, your doctor may opt to cut the dose of CRIZALK CAPSULE.
  • Inform your doctor as soon as possible if you notice any vision loss or changes in your vision, such as difficulties seeing out of one or both eyes.
  • During your therapy with CRIZALK CAPSULE, your doctor may recommend electrocardiograms to ensure that your heart is not causing any difficulties.

Disease/Condition Glossary

Non-small cell lung cancer (NSCLC): Non-small cell lung cancer is a condition in which malignant (cancer) cells develop in the lung tissues. Non-small cell lung cancer is classified into numerous categories. The most important risk factor for non-small cell lung cancer is smoking. There are various forms of non-small cell lung cancer. Different types of cancer cells are found in non-small cell lung cancer. Cancer cells of different types grow and spread in different ways. The several types of non-small cell lung cancer are called after the types of cells found in cancer and how the cells appear under a microscope.

Country of origin

India

Manufacturer/Marketer address

The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051.
Other Info - CRI0067

FAQs

Crizotinib is the active ingredient in CRIZALK CAPSULE. It works by inhibiting an enzyme called tyrosine kinase and causing cancer cells to die. CRIZALK CAPSULE is only provided to individuals whose condition is caused by an ALK tyrosine kinase gene mutation.
In elderly patients, the risk of side effects is more if you take the CRIZALK CAPSULE. For the elderly, it might require dose adjustment, or your doctor might prescribe any other medication safe for the elderly.
No, avoid smoking before starting the treatment and while taking CRIZALK CAPSULE as smoking might alter the effectiveness of CRIZALK CAPSULE.
Take the missed dose as soon as you remember. Skip the missing dose and return to your regular dosing plan if it is time for the next dose. Do not take a double dose to make up for a missing dose.
CRIZALK CAPSULE may cause visual disturbances such as flashes of light, blurred vision, or double vision as a temporary side effect. If it continues or worsens your condition, seek medical advice immediately.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
bannner image

Alcohol

Caution

Consuming alcohol while using CRIZALK CAPSULE is not recommended since it may produce side effects or make you more sensitive to the effects of alcohol.

bannner image

Pregnancy

Caution

CRIZALK CAPSULE is not typically recommended during the pregnancy. Please consult the healthcare professional if you have any concerns regarding this.

bannner image

Breast Feeding

Caution

CRIZALK CAPSULE is not typically recommended if you are a nursing woman. Please consult the healthcare professional if you have any concerns regarding this.

bannner image

Driving

Caution

Do not drive, or you should take special care when driving and using machines as patients taking CRIZALK CAPSULE may experience visual disturbances, dizziness, and tiredness.

bannner image

Liver

Caution

Caution should be taken while using CRIZALK CAPSULE in patients with liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Kidney

Caution

Caution should be taken while using CRIZALK CAPSULE in patients with kidney impairment. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Children

Unsafe

It is not recommended for children as the safety and efficacy have not been established.

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

Add to Cart