CRUXOL 125MG SYRUP 60ML

Written By Bayyarapu Mahesh Kumar , M Pharmacy

Reviewed By Hari Kumar , MBBS

MRP ₹22.1

(Inclusive of all Taxes)

₹3.3 Cashback (15%)

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Prescription drug

Whats That

About CRUXOL 125MG SYRUP

CRUXOL 125MG SYRUP belongs to the group of medicines called analgesics (pain killers), and antipyretics (fever-reducing agents) used to reduce fever and treat mild to moderate pain. Also, it is used to relieve headaches, migraine, toothache, period pain, back pain, muscle pain and rheumatic pains. Pain and fever are caused by the activation of pain receptors due to the release of certain natural chemicals in the body, like prostaglandin.

CRUXOL 125MG SYRUP contains acetaminophen that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins. Thus, reducing pain. Also, CRUXOL 125MG SYRUP affects an area of the brain that regulates body temperature known as the hypothalamic heat-regulating centre. Thereby it reduces fever.

Take CRUXOL 125MG SYRUP as recommended. In some cases, CRUXOL 125MG SYRUP may cause side effects such as nausea, stomach pain and dark-coloured urine. Most of these side effects of CRUXOL 125MG SYRUP do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Do not take CRUXOL 125MG SYRUP if you're allergic to any ingredient in it. CRUXOL 125MG SYRUP is not recommended for children below six years of age. If you are pregnant or breastfeeding, please consult a doctor before using the CRUXOL 125MG SYRUP. Avoid alcohol consumption with CRUXOL 125MG SYRUP as it may increase the risk of liver damage. If you have an impaired nutritional state caused by anorexia (eating disorder), malnutrition or alcohol abuse or if you are dehydrated, inform your doctor before taking the CRUXOL 125MG SYRUP.

Uses of CRUXOL 125MG SYRUP

Fever, Pain relief.

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush, break or chew it.Chewable tablets: Chew the tablet completely and swallow. Do not swallow it as a whole.Orally disintegrating Tablet: Keep the tablet in the mouth and allow it to disintegrate. Do not swallow as a whole. Avoid handling the strip with wet hands.Oral Suspension/Paed drops: Shake the bottle well before each use. Take the recommended dose by mouth using the measuring cup/dosing syringe/dropper.Effervescent Tablets/Dispersible Tablets/Soluble Tablets: Check the label for directions before use. Disperse the tablet in the recommended amount of water and swallow the contents. Do not crush, chew or swallow as a whole.Powder/granules: Check the label for directions before use. Mix the powder/granules in water, mix well and drink immediately.

Medicinal Benefits

CRUXOL 125MG SYRUP contains acetaminophen, an analgesic (pain killer) and antipyretic (reduces fever). It inhibits the production of certain chemical messengers in the brain known as prostaglandins. Thus, reducing pain. Also, CRUXOL 125MG SYRUP affects an area of the brain that regulates body temperature known as the hypothalamic heat-regulating centre. Thereby, it reduces fever.

Storage

Keep CRUXOL 125MG SYRUP out of the sight and reach of children.

Side effects of Cruxol 125mg Syrup 60ml

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Abnormal Breath Sounds

Get urgent medical help if you notice abnormal lung sounds with symptoms, like bluish skin, flare-ups of your nostrils, or trouble breathing.
If you have asthma or allergies, managing these conditions with inhalers and bronchodilators can help prevent abnormal lung sounds.
Infections may need antibiotics or breathing therapy to help open your airways and make breathing easier.
Wash your hands regularly and take other steps to avoid getting sick and spreading germs.
Doing breathing exercises can help improve your lung function and make breathing easier.

Low Oxygen Levels In The Body

Contact your physician right away if you suffer from hypoxia symptoms including chest pain, disorientation, or shortness of breath.
Your doctor can monitor your progress and modify treatment programs with the help of routine follow-up sessions.
Omega-3 supplements may support the transport of oxygen to tissues.
Regular exercise improves cardiovascular health and boosts oxygen delivery to tissues.
Quit smoking, as it can worsen hypoxia.

Drug Warnings

Do not take CRUXOL 125MG SYRUP if you're allergic to any ingredient in it. Caution should be exercised while using CRUXOL 125MG SYRUP in children. If you are pregnant or breastfeeding, please consult a doctor before using CRUXOL 125MG SYRUP. Avoid alcohol consumption with CRUXOL 125MG SYRUP as it may increase the risk of liver damage. If you have an impaired nutritional state caused by anorexia (eating disorder), wrong nutrition or alcohol abuse or if you are dehydrated, inform your doctor before taking CRUXOL 125MG SYRUP. Avoid taking more than recommended doses as it may increase the risk of serious liver damage.

Drug-Drug Interactions

ParacetamolOxazepam

Severe

ParacetamolLeflunomide

Severe

Drug-Drug Interactions

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ParacetamolOxazepam

Severe

How does the drug interact with Cruxol 125mg Syrup 60ml:
Co-administration of Cruxol 125mg Syrup 60ml may decrease the excretion rate of Oxazepam which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Oxazepam and Cruxol 125mg Syrup 60ml, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.

ParacetamolLeflunomide

Severe

How does the drug interact with Cruxol 125mg Syrup 60ml:
Co-administration of Cruxol 125mg Syrup 60ml and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Cruxol 125mg Syrup 60ml and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

ParacetamolKetoconazole

Severe

How does the drug interact with Cruxol 125mg Syrup 60ml:
Co-administration of Cruxol 125mg Syrup 60ml and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Cruxol 125mg Syrup 60ml and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.

ParacetamolKetamine

Severe

How does the drug interact with Cruxol 125mg Syrup 60ml:
Co-administration of ketamine and Cruxol 125mg Syrup 60ml may decrease the effectiveness of Ketamine which could result in a higher blood level.

How to manage the interaction:
Although taking Ketamine and Cruxol 125mg Syrup 60ml together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.

ParacetamolLomitapide

Severe

How does the drug interact with Cruxol 125mg Syrup 60ml:
Co-administration of Lomitapide and Cruxol 125mg Syrup 60ml may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Cruxol 125mg Syrup 60ml and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.

ParacetamolMipomersen

Severe

How does the drug interact with Cruxol 125mg Syrup 60ml:
Co-administration of Mipomersen with Cruxol 125mg Syrup 60ml may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Cruxol 125mg Syrup 60ml and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.

ParacetamolValdecoxib

Severe

How does the drug interact with Cruxol 125mg Syrup 60ml:
Co-administration of Cruxol 125mg Syrup 60ml and Valdecoxib may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Cruxol 125mg Syrup 60ml and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.

ParacetamolTeriflunomide

Severe

How does the drug interact with Cruxol 125mg Syrup 60ml:
Co-administration of Teriflunomide with Cruxol 125mg Syrup 60ml may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Cruxol 125mg Syrup 60ml with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
Acupuncture, massage and physical therapy may also be helpful.
Eat foods rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
Foods containing flavonoids such as soy, berries, broccoli, grapes and green tea help in reducing inflammation.
Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
Avoid smoking and alcohol consumption.

Side Effects of CRUXOL 125MG SYRUP

Nausea
Stomach pain
Dark coloured urine

Habit Forming

No

Therapeutic Class

ANALGESIC AND ANTIPYRETIC AGENT

Author Details

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Reviewed By

Hari Kumar

MBBS

Last Updated

Jul 8, 2025 | 9:29 AM IST

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Drug-Diseases Interactions

ACETAMINOPHEN-125MGMental and behavioural disorders due to use of alcohol

Severe

ACETAMINOPHEN-125MGHepatic failure, not elsewhere classified

Severe

Drug-Diseases Interactions

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ACETAMINOPHEN-125MGMental and behavioural disorders due to use of alcohol

Severe

How does the disease interact with Cruxol 125mg Syrup 60ml:
Chronic alcoholics may have a higher risk of hepatotoxicity when using Cruxol 125mg Syrup 60ml. Patients using Cruxol 125mg Syrup 60ml may cause severe liver damage, including acute liver failure that required a liver transplant and resulted in death.

How to manage the interaction:
Cruxol 125mg Syrup 60ml should be used with caution in patients who consume three or more alcoholic drinks a day. Avoid alcohol consumption while taking Cruxol 125mg Syrup 60ml. If you have nausea, vomiting, fever, rash, anorexia (eating disorder), over-tiredness, upper right stomach pain, dark urine, and jaundice, contact your doctor as these may be signs and symptoms of liver injury.

ACETAMINOPHEN-125MGHepatic failure, not elsewhere classified

Severe

How does the disease interact with Cruxol 125mg Syrup 60ml:
The liver predominantly converts Cruxol 125mg Syrup 60ml to inactive forms. Patients with hepatic impairment may be more prone to toxicity because their minor metabolic pathways are more active.

How to manage the interaction:
Cruxol 125mg Syrup 60ml should be used with caution in patients with kidney insufficiency. Also, it is recommended to avoid drinking alcohol while taking Cruxol 125mg Syrup 60ml.

FAQs

How does CRUXOL 125MG SYRUP work?

CRUXOL 125MG SYRUP works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins. Thus, reducing pain. Also, CRUXOL 125MG SYRUP affects an area of the brain that regulates body temperature known as the hypothalamic heat-regulating centre. Thus, it reduces fever.

Can I take CRUXOL 125MG SYRUP with warfarin?

You are not recommended to take CRUXOL 125MG SYRUP with warfarin as co-administration of these two medicines may increase the risk of bleeding more easily. However, if you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted appropriately to use safely.

Does CRUXOL 125MG SYRUP affect laboratory tests?

CRUXOL 125MG SYRUP may affect how certain tests work such as blood sugar test and uric acid test. Therefore, if you are about to undergo blood test or any laboratory tests, inform your doctor or lab technician that you are taking CRUXOL 125MG SYRUP.

Can I take CRUXOL 125MG SYRUP with other paracetamol containing products?

You are not recommended to take CRUXOL 125MG SYRUP with other paracetamol containing products as it may cause paracetamol overdose.

What happens if i take more than the recommended dose of CRUXOL 125MG SYRUP?

If you take more than recommended doses of CRUXOL 125MG SYRUP, it may cause overdose and lead to serious liver damage. The symptoms of overdose include vomiting, loss of appetite, stomach pain, paleness and nausea. However, if you notice any of these symptoms while taking CRUXOL 125MG SYRUP, please consult a doctor immediately.

Does CRUXOL 125MG SYRUP can damage my liver?

Yes, excessive intake or prolonged intake of CRUXOL 125MG SYRUP can damage your liver. Do not exceed a daily dose of more than 4 gm.

Drug-Drug Interactions Checker List

WARFARIN
CHOLESTYRAMINE
ASPIRIN
METOCLOPRAMIDE
DOMPERIDONE
CHLORAMPHENICOL
RIFAMPICIN
PROBENECID
ISONIAZID
LAMOTRIGINE
CARBAMAZEPINE
PHENYTOIN

Special Advise

If you have a high fever or signs of infection after using CRUXOL 125MG SYRUP for more than three days or if pain persists after using CRUXOL 125MG SYRUP for more than five days, please consult a doctor.

Disease/Condition Glossary

Fever: Fever is an abnormal increase in body temperature due to infection, chemotherapy, or various disease condition. If the body temperature is 98.6°F, it is normal, and if it goes above 100.4°F (38℃), it is called fever or pyrexia. Body temperature increases in response to infection or varied problems to protect the body. Flu is one of the most common causes of fever.

Pain: Pain is a term used to describe any unpleasant feeling or discomfort. It occurs due to nerve damage (in cases of backache, toothache, or muscle pain) or persistent stimulation (in headaches or migraine). Pain may vary from mild to severe, depending on the underlying condition.