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Written By Urvashi Bharti , MBBS
Reviewed By Sunny S , MBBS
Non returnable*
COD available

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Whats That

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Composition :

LAMOTRIGINE-50MG

Manufacturer/Marketer :

Cubit Healthcare

Consume Type :

ORAL

Return Policy :

Not Returnable

About Cugine 50mg Tablet DT

Cugine 50mg Tablet DT belongs to a group of anticonvulsants or anti-epileptics used to treat epilepsy/seizures/fits. Additionally, Cugine 50mg Tablet DT also treats bipolar disorder. Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures, sometimes leading to the unconscious state. Bipolar disorder is a severe brain disorder in which a person experiences extreme mood swings (variance in thinking) and frequent mood and behavioral changes.

Cugine 50mg Tablet DT contains 'Lamotrigine' that reduces the electrical impulses and subsequent firing of the nerve impulses that cause fits. Thus, Cugine 50mg Tablet DT decreases the excessive and abnormal nerve activity in the brain, thereby controlling seizures. 

You are advised to take Cugine 50mg Tablet DT for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as skin rash, headache, nausea, vomiting, dryness in the mouth, insomnia (difficulty in sleeping), sleepiness, dizziness, back pain, fatigue, abdominal pain, blurred vision, double vision, impaired coordination, nasal congestion (stuffy nose), infection. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

To treat your condition effectually, continue taking Cugine 50mg Tablet DT for as long as your doctor has prescribed. Please do not stop taking Cugine 50mg Tablet DT without consulting your doctor to avoid worsening of seizures. Do not take Cugine 50mg Tablet DT if you are pregnant or planning for pregnancy unless prescribed by the doctor as it could lead to serious congenital disabilities. If you are of child-bearing age, use effective contraception while taking Cugine 50mg Tablet DT. Consult your doctor before taking Cugine 50mg Tablet DT if you are breastfeeding. Contact your doctor if your child gets her first-period whilst on treatment with Cugine 50mg Tablet DT. Do not drive or operate machinery as Cugine 50mg Tablet DT causes drowsiness and dizziness. Avoid consuming alcohol along with Cugine 50mg Tablet DT as it could lead to increased dizziness and sleepiness. Consult your doctor immediately if you experience suicidal tendencies.

Uses of Cugine 50mg Tablet DT

Epilepsy (fits), and Bipolar disorder.

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it.Dispersible tablet: Check the label for directions before use. Disperse the tablet in the prescribed amount of water and swallow the contents. Do not crush, chew or swallow as a whole.

Medicinal Benefits

Cugine 50mg Tablet DT belongs to a group of anticonvulsants or anti-epileptics used to treat epilepsy and bipolar disorders. Cugine 50mg Tablet DT contains Lamotrigine, which reduces the electrical impulses and subsequent firing of the nerve impulses that cause fits. Cugine 50mg Tablet DT decreases the excessive and abnormal nerve activity in the brain, thereby helping in controlling seizures. It also suppresses the release of excitatory amino acid glutamate (a chemical messenger that acts as a nerve-exciting agent) in the brain, thereby preventing episodes of fits by stabilizing nerve cell's electrical activity in the brain. Cugine 50mg Tablet DT widely used in pediatric epilepsy because of its acceptable safety profile. Cugine 50mg Tablet DT is not associated with any psychological or physical dependence, and there is no potential for abuse.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Cugine 50mg Tablet DT

  • Skin rash
  • Headache
  • Nausea, vomiting
  • Aggression or irritability
  • Dryness in mouth
  • Insomnia (difficulty in sleeping)
  • Sleepiness
  • Shaking or tremors
  • Dizziness
  • Back pain
  • Fatigue
  • Abdominal pain
  • Blurred vision
  • Double vision
  • Impaired coordination
  • Nasal congestion (stuffy nose)
  • Infection
  • Pain in your back or joints, or elsewhere

Drug Warnings

If you are known to be allergic to Cugine 50mg Tablet DT or any other medicines, please tell your doctor. Please consult your doctor before taking Cugine 50mg Tablet DT if you are pregnant, planning for pregnancy, or breastfeeding. Using this medicine during pregnancy may cause harm to the unborn baby also affect cognitive ability (reasoning, intelligence, problem-solving) later in your child's life. Cugine 50mg Tablet DT should be used with caution in children. If you have depression, liver, kidney, or pancreas problems, urea cycle disorders, inflammation of the tissue that covers the brain and spinal cord, porphyria (a disorder in the formation of red blood pigment) or thrombocytopenia (low levels of platelets), inform your doctor before taking Cugine 50mg Tablet DT. Consult your doctor immediately if you experience suicidal tendencies or mood swings. Do not stop using Cugine 50mg Tablet DT without your doctor's advice. Stopping suddenly may cause a serious, life-threatening type of seizure. Cugine 50mg Tablet DT may cause a severe or life-threatening skin rash, especially in children and in people who take a very high starting dose or those who also take valproic acid. If you have a skin rash, hives, blistering, peeling, or sores in your mouth or around your eyes, please inform your doctor immediately. Cugine 50mg Tablet DT causes drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with Cugine 50mg Tablet DT as it could lead to increased dizziness and sleepiness. 

Drug-Drug Interactions

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LamotrigineDofetilide
Critical
LamotrigineEsketamine
Severe

Drug-Drug Interactions

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LamotrigineDofetilide
Critical
How does the drug interact with Cugine 50mg Tablet DT:
Taking Dofetilide with Cugine 50mg Tablet DT may significantly increase the blood levels of dofetilide. High blood levels of dofetilide can increase the risk of an irregular heart rhythm that may be serious

How to manage the interaction:
Taking Cugine 50mg Tablet DT with Dofetilide is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting and shortness of breath. Do not discontinue any medications without consulting a doctor.
LamotrigineEsketamine
Severe
How does the drug interact with Cugine 50mg Tablet DT:
Coadministration of Cugine 50mg Tablet DT with Esketamine can increase the risk of serious side effects.

How to manage the interaction:
There may be a possibility of interaction between Cugine 50mg Tablet DT and Esketamine, but it can be taken if prescribed by a doctor. Consult your doctor immediately if you feel drowsiness, trouble breathing, dizziness, loss of balance, or confusion, it is advised not to drive or use any hazardous machinery. Do not stop taking any medication without consulting your doctor.
LamotrigineBuprenorphine
Severe
How does the drug interact with Cugine 50mg Tablet DT:
When buprenorphine is used with Cugine 50mg Tablet DT, it may possibly lead to significant adverse effects such as respiratory difficulties, unconsciousness.

How to manage the interaction:
Concomitant administration of buprenorphine alongside Cugine 50mg Tablet DT can result in an interaction, it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. You should avoid driving or operating hazardous machinery until you're aware of how these medications effect you. Do not discontinue any medications without consulting a doctor.
LamotrigineKetamine
Severe
How does the drug interact with Cugine 50mg Tablet DT:
Using Ketamine and Cugine 50mg Tablet DT together can increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Ketamine and Cugine 50mg Tablet DT, you can take these medicines together if prescribed by your doctor. If you feel dizzy, sleepy, confused, have trouble focusing, or have trouble breathing, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
LamotrigineDivalproex
Severe
How does the drug interact with Cugine 50mg Tablet DT:
Coadministration of Divalproex and Cugine 50mg Tablet DT can increase the risk and severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Divalproex and Cugine 50mg Tablet DT, you can take these medicines together if prescribed by your doctor. However, contact your doctor if you experience restlessness, rash, or muscle weakness. Do not stop using any medications without a doctor's advice.
LamotrigineSodium oxybate
Severe
How does the drug interact with Cugine 50mg Tablet DT:
Taking Cugine 50mg Tablet DT with sodium oxybate can increase the risk and severity of side effects.

How to manage the interaction:
Taking Cugine 50mg Tablet DT with Sodium oxybate together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience drowsiness, dizziness, lightheadedness, confusion, depression, low blood pressure, slow or shallow breathing, and impairment in thinking, judgment contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilizing fat instead of glucose for the generation of energy.
  • Atkins diet (high fay and controlled carbohydrates) is recommended for adolescents and adults.
  • Rest well, get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Exercise, meditation, and yoga can help lower stress, decrease pain sensitivity, and improves coping skills.
  • Prepare your living area, small changes may reduce the risk of physical injury during a seizure.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Cugine 50mg Tablet DT Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Cugine 50mg Tablet DT decreases the excessive and abnormal nerve activity in the brain. It balances the brain's chemical messenger and prevents overactivity of the brain, thereby controlling seizure episodes.

Do not discontinue Cugine 50mg Tablet DT without consulting your doctor. To treat your condition effectually, continue taking Cugine 50mg Tablet DT for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Cugine 50mg Tablet DT, your doctor will reduce the dose gradually to avoid worsening of seizures.

Cugine 50mg Tablet DT may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.

Dry mouth could be a side-effect of Cugine 50mg Tablet DT. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Cugine 50mg Tablet DT helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA, this helps in blocking the nerve transmission across the brain and provides a calming effect.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • OXCARBAZEPINE
  • FELBAMATE
  • GABAPENTIN
  • LEVETIRACETAM
  • PREGABALIN
  • TOPIRAMATE
  • ZONISAMIDE
  • VALPROATE
  • CARBAMAZEPINE
  • PHENYTOIN
  • PRIMIDONE
  • PHENOBARBITONE
  • WARFARIN
  • ZIDOVUDINE
  • LOPINAVIR
  • RITONAVIR
  • MOCLOBEMIDE
  • SELEGILINE
  • LINEZOLID
  • AMITRIPTYLINE
  • SERTRALINE
  • UETIAPINE
  • DIAZEPAM
  • OLANZAPINE
  • QUETIAPINE
  • RISPERIDONE
  • PANIPENEM
  • IMIPENEM
  • MEFLOQUINE
  • ERYTHROMYCIN
  • RIFAMPICIN
  • TEMOZOLOMIDE
  • ESTROGEN
  • CHOLESTYRAMINE

Special Advise

  • Contact your doctor if your child gets her first-period whilst on treatment with Cugine 50mg Tablet DT.
  • If you are of child-bearing age, use effective contraception without interruptions during your entire treatment with Cugine 50mg Tablet DT.
  • Consult your doctor immediately if you become pregnant while taking Cugine 50mg Tablet DT.
  • After taking Cugine 50mg Tablet DT if you have thoughts of harming or killing yourself (suicidal behavior), stop taking Cugine 50mg Tablet DT and immediately contact your doctor.

Disease/Condition Glossary

Epilepsy: It is a brain-related problem in which there is a sudden rush of electricity in the brain. This sudden, uncontrolled disturbance in nerve cell's electrical activity in the brain results in recurrent seizures (fits), sometimes leading to the unconscious state. In patients with seizures, the typical brain electrical pattern is disrupted by sudden bursts of electrical impulses that affect an individual's consciousness, movements, or sensations. Seizures are of two types: generalized and partial seizures. Generalized seizures affect the entire brain, whereas partial seizures affect only a part of the brain. Seizures can cause uncontrollable muscle twitches and spasms. Stronger seizures may cause people to become confused or unconscious. Possible causes include high fever, trauma, genetic disorder, brain injury, or stroke.

Bipolar disorder: Bipolar disorder, also known as manic depression or bipolar disease, is a mental health disorder associated with episodes of mood swings ranging from manic highs to depressive lows.

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