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Reviewed By Sunny S , MBBS
Non returnable*
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Manufacturer/Marketer :

Innovative Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Cyclobrex 20mg/325mg Tablet

Cyclobrex 20mg/325mg Tablet is a combination drug primarily used in the treatment of spasmodic pain and discomfort due to biliary colic, intestinal colic, renal colic and spasmodic dysmenorrhea (painful irregular periods). It also helps alleviate the symptoms of irritable bowel syndrome (IBS). Colic is the intensive and uncontrollable crying in the babies for a prolonged period for no certain reason. Dysmenorrhea (Abdominal cramps) is an unpleasant sensory and emotional experience associated with irregular periods. It occurs just before or during menses. Irritable bowel syndrome is an intestinal disorder that causes stomach pain, wind, constipation, and diarrhoea.

Cyclobrex 20mg/325mg Tablet is composed of two medicines: Dicyclomine (antispasmodic/anticholinergic agent) and Paracetamol (analgesic). Dicyclomine/Dicycloverine helps in blocking the activity of certain natural substances that are responsible to cause pain. Paracetamol has both analgesic (pain reducer) and antipyretic (fever reducer) properties, which also decreases inflammation.

Your doctor will decide the dose and duration based on the severity of your pain. Common side effects of Cyclobrex 20mg/325mg Tablet include experience dizziness, nausea (feeling sick), digestion problems like constipation, flatulence, diarrhoea, and skin reactions like rashes, hives. Most of the side effects of Cyclobrex 20mg/325mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Let your doctor know if you are sensitive or allergic to Cyclobrex 20mg/325mg Tablet or any other medications. Before using Cyclobrex 20mg/325mg Tablet, let your doctor know if you have liver, kidney or heart diseases, and any other medical history. Some antacids may inhibit the absorption of Cyclobrex 20mg/325mg Tablet, hence consult your doctor. Cyclobrex 20mg/325mg Tablet may cause dizziness, hence do not drive or operate machinery until you feel better. Pregnant and breastfeeding women should consult their doctor before using Cyclobrex 20mg/325mg Tablet. Cyclobrex 20mg/325mg Tablet should be used in children only when recommended by a doctor.

Uses of Cyclobrex 20mg/325mg Tablet

Biliary colic, intestinal colic, renal colic, spasmodic dysmenorrhea, and symptoms of irritable bowel syndrome.

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Oral Syrup/Liquid/Pediatric drops: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Medicinal Benefits

Cyclobrex 20mg/325mg Tablet is composed of two medicines namely: Dicyclomine (antispasmodic) and Paracetamol (mild analgesic and fever reducer). Cyclobrex 20mg/325mg Tablet helps relieve spasmodic pain and discomfort due to biliary colic, intestinal colic, renal colic, and spasmodic dysmenorrhea (painful irregular menses/periods). Dicyclomine helps in blocking the activity of certain natural substances in the body responsible for causing pain. On the other hand, Paracetamol has analgesic (pain reducer) and antipyretic (fever reducer) properties, decreasing inflammation. Together, they effectively reduce pain and inflammation in conditions of intestine inflammation, spasm and painful menstruation.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Cyclobrex 20mg/325mg Tablet

  • Dizziness
  • Nausea (feeling sick)
  • Constipation
  • Flatulence
  • Diarrhoea
  • Rashes/hives

Drug Warnings

Let your doctor know if you are sensitive to Cyclobrex 20mg/325mg Tablet or its components. Cyclobrex 20mg/325mg Tablet should be used with caution and only under a doctor’s supervision if you have stomach/intestinal problems and diarrhoea due to intestine surgeries like ileostomy and colostomy. Pregnant and breastfeeding women should use Cyclobrex 20mg/325mg Tablet with proper consultation and caution. Cyclobrex 20mg/325mg Tablet may cause blurry vision and dizziness affecting your mental focus, hence do not drive or operate machinery until you feel better. Drinking alcohol may worsen the side effects; therefore, it is advised to avoid the alcohol intake while using Cyclobrex 20mg/325mg Tablet. Cyclobrex 20mg/325mg Tablet should be used in children only when prescribed by the doctor.

Drug-Drug Interactions

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DicyclominePotassium chloride
Critical
DicyclominePramlintide
Critical

Drug-Drug Interactions

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DicyclominePotassium chloride
Critical
How does the drug interact with Cyclobrex 20mg/325mg Tablet:
Co-administration of Cyclobrex 20mg/325mg Tablet with Potassium chloride can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Cyclobrex 20mg/325mg Tablet with Potassium chloride is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not discontinue the medication without consulting a doctor.
DicyclominePramlintide
Critical
How does the drug interact with Cyclobrex 20mg/325mg Tablet:
Co-administration of Pramlintide with Cyclobrex 20mg/325mg Tablet can increase the risk of reduced gastrointestinal movement.

How to manage the interaction:
Taking Cyclobrex 20mg/325mg Tablet with Pramlintide is not recommended, please consult your doctor before taking it. Do not discontinue the medication without consulting a doctor.
DicyclominePotassium citrate
Critical
How does the drug interact with Cyclobrex 20mg/325mg Tablet:
Taking Cyclobrex 20mg/325mg Tablet and Potassium citrate together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Cyclobrex 20mg/325mg Tablet with Potassium citrate is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
ParacetamolLeflunomide
Severe
How does the drug interact with Cyclobrex 20mg/325mg Tablet:
Co-administration of Cyclobrex 20mg/325mg Tablet and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Cyclobrex 20mg/325mg Tablet and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ParacetamolTeriflunomide
Severe
How does the drug interact with Cyclobrex 20mg/325mg Tablet:
Co-administration of Teriflunomide with Cyclobrex 20mg/325mg Tablet may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Cyclobrex 20mg/325mg Tablet with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
ParacetamolKetoconazole
Severe
How does the drug interact with Cyclobrex 20mg/325mg Tablet:
Co-administration of Cyclobrex 20mg/325mg Tablet and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Cyclobrex 20mg/325mg Tablet and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.
ParacetamolKetamine
Severe
How does the drug interact with Cyclobrex 20mg/325mg Tablet:
Co-administration of ketamine and Cyclobrex 20mg/325mg Tablet may decrease the effectiveness of Ketamine which could result in a higher blood level.

How to manage the interaction:
Although taking Ketamine and Cyclobrex 20mg/325mg Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
ParacetamolLomitapide
Severe
How does the drug interact with Cyclobrex 20mg/325mg Tablet:
Co-administration of Lomitapide and Cyclobrex 20mg/325mg Tablet may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Cyclobrex 20mg/325mg Tablet and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolMipomersen
Severe
How does the drug interact with Cyclobrex 20mg/325mg Tablet:
Co-administration of Mipomersen with Cyclobrex 20mg/325mg Tablet may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Cyclobrex 20mg/325mg Tablet and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ParacetamolOxazepam
Severe
How does the drug interact with Cyclobrex 20mg/325mg Tablet:
Co-administration of Cyclobrex 20mg/325mg Tablet may decrease the excretion rate of Oxazepam which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Oxazepam and Cyclobrex 20mg/325mg Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid or limit the intake of alcohol and caffeine.
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Limit taking high fibre foods, foods and drinks that contain chocolate, alcohol, caffeine, fructose, or sorbitol, carbonated drinks, fried, and fatty foods. 
  • Do not have large meals at a time, instead try having small and simpler meals at regular intervals, including fresh fruits and vegetables in your diet.
  • Practice yoga and recreation techniques to manage your emotional stress.
  • If you are lactose intolerant, avoid using dairy products since it can worsen your IBS.
  • If you cannot take dairy products, it is advised to include other calcium-rich foods like leafy greens, beans, nuts, and seeds.
  • Drink plenty of fluids and dress lightly to prevent heatstroke and dehydration.
  • Avoid overly sweating activities like hard exercises and using hot tubs.

Habit Forming

No

Therapeutic Class

ANTISPASMODICS/SPASMOLYTIC ANALGESICS

Cyclobrex 20mg/325mg Tablet Substitute

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Cyclobrex 20mg/325mg Tablet works by relaxing the muscles and inhibiting natural gut movements, thereby relieving muscle spasms and cramps in the stomach and intestine, abdominal pain, constipation and other GI discomforts.

Antacids may lower the absorption of Cyclobrex 20mg/325mg Tablet and reduce its efficacy. It is advised to take antacid and Cyclobrex 20mg/325mg Tablet at different times. If you take antacid after meals, please take Cyclobrex 20mg/325mg Tablet before meals.

If you suffer from IBS, limit taking high fibre foods, foods and drinks that contain chocolate, alcohol, caffeine, fructose, or sorbitol, carbonated drinks, fried, and fatty foods. Do not have large meals; instead, try having small and simpler meals at regular intervals, including fresh fruits and vegetables in your diet.

The use of Cyclobrex 20mg/325mg Tablet can cause diarrhea in some cases. In the case of diarrhea, increase the intake of fluids like drink plenty of water. If still diarrhea persists, inform your doctor and do as advised.

Yes, the use of Cyclobrex 20mg/325mg Tablet can cause dry mouth. If you feel excessively thirsty, increase fluid intake, and avoid spicy and salty food.

Drug-Drug Interactions Checker List

  • CHOLESTYRAMINE
  • DOMPERIDONE
  • ZIDOVUDINE
  • WARFARIN
  • TACROLIMUS
  • METHOTREXATE
  • POTASSIUM CITRATE

Disease/Condition Glossary

Colic: Colic is the intensive and uncontrollable crying in the babies for a prolonged period for no certain reason. Colicky babies usually have distended bellies, release gas, raise their legs to the chest, and bend or arch their backs.

Irritable Bowel Syndrome (IBS): It is also termed as IBS colitis, mucous colitis, spastic colon, nervous colon, and spastic bowel. It is an inflammatory bowel disease that affects the large intestine. Symptoms of an IBS include abdominal pain, bloating, diarrhoea, mucus in stools, wind, constipation, tiredness, anxiety, depression, heartburn, indigestion, and headaches.

Dysmenorrhea refers to abdominal cramps/pain and an unpleasant sensory/emotional experience associated with irregular periods. It occurs just before or during menses. 

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