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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Santoshini Reddy G , M Pharmacy
Non returnable*
COD available

Online payment accepted

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Whats That

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Composition :

DACLATASVIR-30MG

Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Daclacure 30mg Tablet

Daclacure 30mg Tablet is an antiviral medicine used along with sofosbuvir, with or without ribavirin, to treat chronic hepatitis C viral genotype 1 or 3 infection. It is a serious infection caused by the hepatitis C virus. It is a contagious infection that spreads from person to person and affects the liver. Daclacure 30mg Tablet is only used in treating the infection. It does not cure or prevent further liver complications.

Daclacure 30mg Tablet contains Daclatasvir, which belongs to the class of hepatitis C virus (HCV) NS5A inhibitors. It works by blocking the activity of the hepatitis C virus in the liver cells. This causes viral DNA termination and reduces the amount of hepatitis C virus in the body.

Daclacure 30mg Tablet may cause certain side effects such as headache, fatigue, weakness, confusion, chest pain, nausea, diarrhoea, shortness of breath, dizziness and lightheadedness. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. Use it as suggested by your doctor. Your doctor will decide the duration of the medicine based on your health condition.

Daclacure 30mg Tablet should be avoided if you are allergic to it. If you are pregnant or breastfeeding, inform your doctor before starting treatment with this medicine. Daclacure 30mg Tablet is not recommended for children below 18 years of age as efficacy and safety have not been established. Inform your doctor if you have any underlying conditions like hepatitis B virus infection, liver cirrhosis, nephrotoxicity, liver transplant, heart problem, kidney problems, or HIV infection, as it may cause serious side effects. Daclacure 30mg Tablet may cause hepatitis B infection reactivation and bradycardia (slow heart rate) in some patients. Hence, patients should be monitored carefully for any changes.

Uses of Daclacure 30mg Tablet

Hepatitis C virus infection.

Directions for Use

Swallow the tablet as a whole with a glass of water. Do not chew, break or crush the tablet.

Medicinal Benefits

Daclacure 30mg Tablet contains Daclatasvir, which belongs to the class of hepatitis C virus (HCV) NS5A inhibitors. It works by blocking the activity of the hepatitis C virus in the liver cells. This causes viral DNA termination and, therefore, reduces the amount of hepatitis C virus in the body.

Storage

Store in a cool and dry place away from sunlight
Side effects of Daclacure 30mg Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Drug Warnings

Daclacure 30mg Tablet should be avoided if you are allergic to it. If you are pregnant or breastfeeding, inform your doctor before starting treatment with this medicine. Daclacure 30mg Tablet is not recommended for children below 18 years of age as efficacy and safety have not been established. Inform your doctor if you have any underlying conditions like hepatitis B virus infection, liver cirrhosis, nephrotoxicity, liver transplant, heart problem, other kidney problems, or HIV infection, as it may cause serious side effects. Daclacure 30mg Tablet may cause hepatitis B infection reactivation and bradycardia in some patients. Hence, patients should be monitored carefully for any changes.

Drug-Drug Interactions

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DaclatasvirCarbamazepine
Critical
DaclatasvirPrimidone
Critical

Drug-Drug Interactions

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DaclatasvirCarbamazepine
Critical
How does the drug interact with Daclacure 30mg Tablet:
When Daclacure 30mg Tablet is taken with Carbamazepine, it may decrease the blood levels of Daclacure 30mg Tablet, which may make Daclacure 30mg Tablet less effective in treating your Hepatitis C.

How to manage the interaction:
Taking Daclacure 30mg Tablet with Carbamazepine is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without a doctor's advice.
DaclatasvirPrimidone
Critical
How does the drug interact with Daclacure 30mg Tablet:
Coadministration of Daclacure 30mg Tablet with primidone may decrease the blood levels of Daclacure 30mg Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although there is an interaction between Primidone and Daclacure 30mg Tablet, they can be taken together if advised by your doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DaclatasvirCeritinib
Severe
How does the drug interact with Daclacure 30mg Tablet:
Taking Ceritinib with Daclacure 30mg Tablet can significantly increase the blood levels of Daclacure 30mg Tablet.

How to manage the interaction:
Taking Ceritinib with Daclacure 30mg Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as headache, weakness, nausea, and loose stools. Do not stop using any medications without a doctor's advice.
DaclatasvirMifepristone
Severe
How does the drug interact with Daclacure 30mg Tablet:
Co-administration of Daclacure 30mg Tablet with mifepristone may significantly increase the levels of Daclacure 30mg Tablet, which may increase the risk of side effects.

How to manage the interaction:
Taking Daclacure 30mg Tablet with mifepristone together can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience symptoms such as headache, fatigue, nausea, and diarrhea. Do not discontinue any medications without consulting a doctor.
DaclatasvirModafinil
Severe
How does the drug interact with Daclacure 30mg Tablet:
Combining Daclacure 30mg Tablet with Modafinil may significantly reduce the blood levels of Daclacure 30mg Tablet. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Daclacure 30mg Tablet with Modafinil together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any symptoms like Fatigue, Fever, Jaundice, Pain in the right upper abdomen, Abdominal swelling, or Dark urine make sure to contact your doctor right away. Do not stop using any medications without first talking to your doctor.
DaclatasvirVoriconazole
Severe
How does the drug interact with Daclacure 30mg Tablet:
Taking Daclacure 30mg Tablet with Voriconazole may significantly increase the blood levels of Daclacure 30mg Tablet which increases risk of side effects.

How to manage the interaction:
Although taking Daclacure 30mg Tablet and Voriconazole together may result in an interaction, they can be taken together if a doctor prescribes it. However, if you experience headache, nausea, and diarrhea, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
DaclatasvirRifampicin
Severe
How does the drug interact with Daclacure 30mg Tablet:
Taking Daclacure 30mg Tablet with rifampicin can decrease the blood levels of Daclacure 30mg Tablet, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Daclacure 30mg Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
DaclatasvirColchicine
Severe
How does the drug interact with Daclacure 30mg Tablet:
Coadministration of colchicine with Daclacure 30mg Tablet may increase the blood levels of colchicine, increasing the risk of side effects.

How to manage the interaction:
Although taking Colchicine and Daclacure 30mg Tablet together may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience nausea, vomiting, abdominal pain, numbness or tingling in your hands and legs, muscle pain, or weakness, contact your doctor immediately. Do not discontinue any medication without consulting your doctor.
DaclatasvirEfavirenz
Severe
How does the drug interact with Daclacure 30mg Tablet:
When Daclacure 30mg Tablet is taken with Efavirenz, the levels and effectiveness of Daclacure 30mg Tablet may be reduced.

How to manage the interaction:
Taking Daclacure 30mg Tablet with Efavirenz together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
DaclatasvirKetoconazole
Severe
How does the drug interact with Daclacure 30mg Tablet:
Coadministration of Ketoconazole and Daclacure 30mg Tablet can increase the blood level of Daclacure 30mg Tablet. This may increase the risk and/or severity of side effects (headache, fatigue, nausea, and diarrhea).

How to manage the interaction:
Although taking Ketoconazole and Daclacure 30mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience headache, fatigue, nausea, diarrhea more severely, consult a doctor. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat more vegetables, fruits, and whole grains such as brown rice, oats, quinoa, and barley.
  • Include healthy fats like avocados, olive oil, and nuts.
  • Drink plenty of water for better processing of food by the body.
  • Avoid sugary foods such as cake, cookies, packaged baked food, or soda. Also, avoid heavy salt foods.
  • Avoid foods containing saturated fats such as fried foods, fatty cuts of meat, sour cream, and butter.
  • Try to eat low-fat or non-fat dairy products to minimise damage to the liver.

Habit Forming

No

Therapeutic Class

ANTIVIRALS

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Daclacure 30mg Tablet contains Daclatasvir, which works by blocking the activity of the hepatitis C virus in the liver cells. This causes viral DNA termination and reduces the amount of hepatitis C virus in the body.

Avoid receiving Daclacure 30mg Tablet if you are allergic to it or other medicines of the same class. Also, this medicine should not be used along with CYP3A inducer drugs such as rifampicin, carbamazepine, phenytoin, etc., as it can cause serious adverse effects. Concomitant use of Daclacure 30mg Tablet along with amiodarone should be avoided due to the risk of severe bradycardia (slow heart rate).

Drug-Drug Interactions Checker List

  • AMIODARONE
  • KETOCONAZOLE
  • VORICONAZOLE
  • DABIGATRAN
  • WARFARIN
  • ATAZANAVIR
  • NELFINAVIR
  • NALOXONE
  • BUPRENORPHINE
  • ATORVASTATIN
  • PRAVASTATIN
  • PHENYTOIN
  • PHENOBARBITONE
  • RIFAMPICIN
  • CARBAMAZEPINE

Special Advise

  • Close monitoring of liver and kidney function tests is required while on treatment with Daclacure 30mg Tablet to monitor liver and kidney functions.
  • Sudden withdrawal of Daclacure 30mg Tablet should be avoided as it can cause severe acute exacerbations of hepatitis or other serious side effects.

Disease/Condition Glossary

Hepatitis C Virus Infection: It is a contagious infection caused by the hepatitis C virus affecting the liver. This infection spreads from person to person through blood contact (being pricked with a contaminated needle or using a razor), intimate contact with the infected person, direct contact with infected blood, or contact with any other personal items with leftovers of infected fluid or even from mother to baby during birth. The symptoms may not appear immediately. Some may take between 2 to 12 weeks to appear. Few people may have mild to moderate symptoms such as dark urine, loss of appetite, fever, joint pain, or stomach discomfort. The complications of untreated chronic hepatitis C include liver cancer or liver cirrhosis (scarring).

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