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  3. Dacoplice 30 mg Tablet 30's

Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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COD available

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Composition :

DACOMITINIB-30MG

Manufacturer/Marketer :

Pfizer Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Dacoplice 30 mg Tablet

Dacoplice 30 mg Tablet is an anti-cancer medicine used in the treatment of non-small cell lung cancer (NSCLC). It is a common form of lung cancer in which abnormal cells grow in the lung tissues. Dacoplice 30 mg Tablet is used as a first-line therapy in the treatment of metastatic NSCLC with epidermal growth factor receptor (EGFR) exon 19 deletion or exon 21 L858R substitution mutations.

Dacoplice 30 mg Tablet consists of Dacominitib, which belongs to the class of medicines known as kinase inhibitors. It works by stopping the action of an enzyme (tyrosine kinase) that causes the multiplication of cancerous cells. This prevents the abnormal growth of cancer cells and thus reduces the further spread to other parts of the body.

Dacoplice 30 mg Tablet may cause certain side effects such as diarrhea, rash, nausea, vomiting, dry skin, mouth sores, nail inflammation, ache, cough, abdominal pain, hair loss, decreased appetite, decreased weight loss, and itching. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Dacoplice 30 mg Tablet should be taken as advised by your doctor. Do not take more than the recommended dose. Your doctor will decide the dose of Dacoplice 30 mg Tablet based on the severity of your condition.

Avoid taking Dacoplice 30 mg Tablet if you are allergic to it or any other components of it. Before taking Dacoplice 30 mg Tablet , inform your doctor if you have/had liver or kidney disease and lung disease other than lung cancer. This medicine is known to cause embryo-fetal toxicity. It is not recommended for use in pregnancy and breastfeeding. Elderly people are more sensitive to medicine, so the dose may have to be adjusted according to their condition.

Uses of Dacoplice 30 mg Tablet

Non-small cell lung cancer (NSCLC).

Directions for Use

Take Dacoplice 30 mg Tablet as prescribed by the doctor. Swallow it as a whole with a glass of water. Do not crush, break, or chew it.

Medicinal Benefits

Dacoplice 30 mg Tablet contains Dacominitib, which belongs to the class of medicines known as kinase inhibitors. It works by stopping the action of a tyrosine kinase enzyme that causes the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body. In this way, Dacoplice 30 mg Tablet stops the body's production, spread and growth of cancerous cells.

Storage

Store in a cool and dry place away from sunlight
Side effects of Dacoplice 30 mg Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Soak the infected nail in warm water for 10 to 20 minutes, a few times a day.
  • Apply topical antibiotic ointment as advised by the doctor.
  • Avoid irritants and excessive moisture.
  • Consume more protein-rich foods and healthy fats like beans, avocados, cheese, nuts and lean meats to minimize appetite.
  • Prefer foods high in fiber to help feel full for a long time.
  • If you have decreased appetite, eat only when you are hungry.
  • Eat several small meals or snacks all day.
  • Try to take only small sips of fluids while eating.
  • Apply moisturizer immediately after showering or bathing.
  • Use a moisturizer containing lanolin, petroleum jelly, glycerine, hyaluronic acid or jojoba oil.
  • Do not use hot water for bathing. Instead use warm water and limit showers and bath to 5 to 10 minutes.
  • Apply a sunscreen with SPF-30 or higher.
  • Avoid harsh soaps, detergents and perfumes.
  • Do not scratch or rub the skin.
  • Drink adequate water to prevent dehydration.
  • Wear pants, full sleeves and a wide-brimmed hat while going out in the sun.
  • Weight loss without physical activity needs immediate medical attention.
  • Get a physical examination and blood tests done to identify factors causing weight loss that could be related to metabolism and thyroid function.
  • Avoid smoking and alcohol intake as it can alter your liver condition and increase your weight loss.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes of weight loss.
  • Talk to your dietician and consume food which can maintain ideal weight.
  • Eat protein-rich foods like fish, poultry, eggs, and legumes.
  • Include foods with minerals and vitamins essential for hair health.
  • Join a support group to connect with others experiencing hair loss.
  • Openly discuss your feelings about hair loss.
  • Consider covering up with wigs, hats, or scarves.
  • Be patient and avoid seeking miracle cures.

Drug Warnings

To treat your condition effectually, continue taking Dacoplice 30 mg Tablet for the period that your doctor has prescribed. Avoid taking Dacoplice 30 mg Tablet if you are allergic to it or any other components present in it. Caution should be exercised if you have/had liver or kidney disease, eye problems, lung disease other than lung cancer, severe cough, and breathing difficulty. This medicine is known to cause embryo-fetal toxicity. Hence, inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment. Effective birth control pills should be used for at least 17 days after the last dose of the medicine. Dacoplice 30 mg Tablet may cause severe diarrhea, severe skin conditions, and Interstitial lung disease in some patients. Hence, inform your doctor about your complete medication and medical history before taking Dacoplice 30 mg Tablet . Breastfeeding should be discontinued in nursing mothers during the treatment as it passes into breast milk and may cause a possible risk to the infant. Avoid driving and operating machines, as this medicine may cause visual disturbances. This medicine is not recommended for use in children as the safety and efficacy are not established.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Dacoplice 30 mg Tablet:
Taking Atomoxetine and Dacoplice 30 mg Tablet may significantly increase the blood levels of atomoxetine. This can increase side effects (dizziness, dry mouth, loss of appetite, sleep disturbances, and heart palpitations).

How to manage the interaction:
Although taking Atomoxetine and Dacoplice 30 mg Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience dizziness, dry mouth, loss of appetite, sleep disturbances, and rapid heartbeats, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Dacoplice 30 mg Tablet:
Taking Pantoprazole can make Dacoplice 30 mg Tablet less effective by reducing its absorption in the body.

How to manage the interaction:
Taking Pantoprazole with Dacoplice 30 mg Tablet together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dacoplice 30 mg Tablet:
Esomeprazole can make Dacoplice 30 mg Tablet less effective by reducing its absorption and lowering its concentration in the blood.

How to manage the interaction:
Co-administration of Esomeprazole with Dacoplice 30 mg Tablet can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
How does the drug interact with Dacoplice 30 mg Tablet:
Co-administration of Lansoprazole can make Dacoplice 30 mg Tablet less effective by reducing its absorption and lowering its concentration in the blood.

How to manage the interaction:
Co-administration of Lansoprazole with Dacoplice 30 mg Tablet can result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • After your treatment begins, several dietary adjustments can help you control side effects.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • Plant-based proteins are among the greatest meals during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans and legumes.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Dacoplice 30 mg Tablet contains Dacominitib, which works by stopping the action of a tyrosine kinase enzyme that causes the multiplication of cancerous cells.

The most common sign of lung cancer is a cough that lasts long and gets worse with time. Sometimes, a patient may notice blood in the cough. Chest pain is also a sign of lung cancer, followed by coughing.

Drug-Drug Interactions Checker List

  • ESOMEPRAZOLE
  • RABEPRAZOLE
  • PANTOPRAZOLE
  • LANSOPRAZOLE
  • CODEINE
  • HALOPERIDOL
  • ARIPIPRAZOLE
  • NORTRIPTYLINE

Special Advise

  • Avoid being under the sun for a long time, as prolonged duration of sun exposure may cause serious hypersensitivity reactions.
  • Your doctor may suggest blood tests to check for any changes in the patient during the treatment period.

Disease/Condition Glossary

Non-Small Cell Lung Cancer (NSCLC): Lung cancer is defined as an Uncontrollable growth of abnormal cells in one or both lungs. These abnormal cells do not carry out normal lung cell functions and do not develop into healthy lung tissue. There are different forms of lung cancer. The most common form of lung cancer is non-small cell lung cancer (NSCLC). It happens when cells that form the lining of the lung start growing uncontrollably. Cancerous cells of the lung spread off and travel through the bloodstream to distant regions of the body and grow. It is mostly seen in persons who smoke. Symptoms may include chest pain, weight loss, hoarseness, and difficulty breathing.

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